Aliases for XKR8 Gene
External Ids for XKR8 Gene
Previous GeneCards Identifiers for XKR8 Gene
GeneCards Summary for XKR8 Gene
XKR8 (XK Related 8) is a Protein Coding gene. An important paralog of this gene is XKR4.
UniProtKB/Swiss-Prot for XKR8 Gene
Promotes phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment. Has no effect on calcium-induced exposure of phosphatidylserine. Activated upon caspase cleavage, suggesting that it does not act prior the onset of apoptosis.