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Aliases for XKR7 Gene

Aliases for XKR7 Gene

  • XK, Kell Blood Group Complex Subunit-Related Family, Member 7 2 3
  • X Kell Blood Group Precursor-Related Family, Member 7 2 3
  • C20orf159 3 4
  • Chromosome 20 Open Reading Frame 159 2
  • XK-Related Protein 7 3
  • DJ310O13.4 3
  • XRG7 4

External Ids for XKR7 Gene

Previous HGNC Symbols for XKR7 Gene

  • C20orf159

Previous GeneCards Identifiers for XKR7 Gene

  • GC20P030020
  • GC20P030555
  • GC20P027344

Summaries for XKR7 Gene

GeneCards Summary for XKR7 Gene

XKR7 (XK, Kell Blood Group Complex Subunit-Related Family, Member 7) is a Protein Coding gene. An important paralog of this gene is XKR9.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for XKR7 Gene

Genomics for XKR7 Gene

Regulatory Elements for XKR7 Gene

Genomic Location for XKR7 Gene

31,968,002 bp from pter
32,003,387 bp from pter
35,386 bases
Plus strand

Genomic View for XKR7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for XKR7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for XKR7 Gene

Proteins for XKR7 Gene

  • Protein details for XKR7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    XK-related protein 7
    Protein Accession:
    Secondary Accessions:
    • Q9NUG5

    Protein attributes for XKR7 Gene

    579 amino acids
    Molecular mass:
    63826 Da
    Quaternary structure:
    No Data Available

neXtProt entry for XKR7 Gene

Proteomics data for XKR7 Gene at MOPED

Post-translational modifications for XKR7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for XKR7 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for XKR7 Gene

Domains for XKR7 Gene

Protein Domains for XKR7 Gene

Suggested Antigen Peptide Sequences for XKR7 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the XK family.
  • Belongs to the XK family.
genes like me logo Genes that share domains with XKR7: view

Function for XKR7 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for XKR7 Gene

Localization for XKR7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for XKR7 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for XKR7 Gene COMPARTMENTS Subcellular localization image for XKR7 gene
Compartment Confidence
plasma membrane 3
cytosol 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for XKR7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with XKR7: view

Pathways for XKR7 Gene

SuperPathways for XKR7 Gene

No Data Available

Interacting Proteins for XKR7 Gene

Gene Ontology (GO) - Biological Process for XKR7 Gene


No data available for Pathways by source for XKR7 Gene

Transcripts for XKR7 Gene

mRNA/cDNA for XKR7 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for XKR7 Gene

XK, Kell blood group complex subunit-related family, member 7:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for XKR7 Gene

No ASD Table

Relevant External Links for XKR7 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for XKR7 Gene

mRNA expression in normal human tissues for XKR7 Gene

mRNA differential expression in normal tissues according to GTEx for XKR7 Gene

This gene is overexpressed in Brain - Cerebellum (17.4), Brain - Cerebellar Hemisphere (15.2), and Pituitary (6.8).

Protein differential expression in normal tissues for XKR7 Gene

This gene is overexpressed in Cerebrospinal fluid (51.4) and Fetal Brain (15.2).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for XKR7 Gene

SOURCE GeneReport for Unigene cluster for XKR7 Gene Hs.666444

genes like me logo Genes that share expressions with XKR7: view

Expression partners for XKR7 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for XKR7 Gene

Orthologs for XKR7 Gene

This gene was present in the common ancestor of animals.

Orthologs for XKR7 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia XKR7 35
  • 91.25 (n)
  • 92.23 (a)
XKR7 36
  • 92 (a)
(Canis familiaris)
Mammalia XKR7 35
  • 92.63 (n)
  • 93.76 (a)
XKR7 36
  • 93 (a)
(Mus musculus)
Mammalia Xkr7 35
  • 88.08 (n)
  • 91.19 (a)
Xkr7 16
Xkr7 36
  • 91 (a)
(Pan troglodytes)
Mammalia XKR7 35
  • 99.42 (n)
  • 99.14 (a)
XKR7 36
  • 86 (a)
(Rattus norvegicus)
Mammalia Xkr7 35
  • 88.31 (n)
  • 91.19 (a)
(Monodelphis domestica)
Mammalia XKR7 36
  • 77 (a)
(Gallus gallus)
Aves XKR7 35
  • 78.05 (n)
  • 77.16 (a)
XKR7 36
  • 74 (a)
(Anolis carolinensis)
Reptilia XKR7 36
  • 74 (a)
(Danio rerio)
Actinopterygii zgc:198371 35
  • 65.82 (n)
  • 62.23 (a)
xkr7 36
  • 63 (a)
XKR7 (2 of 2) 36
  • 58 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG32579 36
  • 20 (a)
(Caenorhabditis elegans)
Secernentea ced-8 36
  • 22 (a)
Species with no ortholog for XKR7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for XKR7 Gene

Gene Tree for XKR7 (if available)
Gene Tree for XKR7 (if available)

Paralogs for XKR7 Gene

Paralogs for XKR7 Gene

(3) SIMAP similar genes for XKR7 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with XKR7: view

Variants for XKR7 Gene

Sequence variations from dbSNP and Humsavar for XKR7 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs714604 -- 31,997,959(+) ATGGC(A/G)TGGCT utr-variant-3-prime
rs714605 -- 31,998,221(+) GATGA(A/G)GTTCC utr-variant-3-prime
rs752390 -- 31,992,415(-) GCTCC(A/G)GGTCT intron-variant
rs754568 -- 31,982,062(-) TCCAG(A/C)AATGC intron-variant
rs2004822 -- 31,991,981(+) GCATG(A/G)TGGCG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for XKR7 Gene

Variant ID Type Subtype PubMed ID
nsv833952 CNV Gain 17160897
nsv3348 CNV Loss 18451855
esv2637856 CNV Loss 19546169
esv29218 CNV Loss 19812545

Relevant External Links for XKR7 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for XKR7 Gene

Disorders for XKR7 Gene

No disorders were found for XKR7 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for XKR7 Gene

Publications for XKR7 Gene

  1. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4

Products for XKR7 Gene

Sources for XKR7 Gene

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