Subcategory (RNA class) for XIST Gene
Quality Score for this RNA gene is
Aliases for XIST Gene
Previous Symbols for XIST Gene
X inactivation is an early developmental process in mammalian females that transcriptionally silences one of the pair of X chromosomes, thus providing dosage equivalence between males and females. The process is regulated by several factors, including a region of chromosome X called the X inactivation center (XIC). The XIC comprises several non-coding and protein-coding genes, and this gene was the first non-coding gene identified within the XIC. This gene is expressed exclusively from the XIC of the inactive X chromosome, and is essential for the initiation and spread of X-inactivation. The transcript is a spliced RNA. Alternatively spliced transcript variants have been identified, but their full length sequences have not been determined. Mutations in the XIST promoter cause familial skewed X inactivation. [provided by RefSeq, Apr 2012]
GeneCards Summary for XIST Gene
XIST (X Inactive Specific Transcript (Non-Protein Coding)) is an RNA Gene, and belongs to the lncRNA class. Diseases associated with XIST include x-inactivation, familial skewed.
fRNAdb sequence ontologies for XIST Gene
ncRNA: An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product.