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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

XIRP1 Gene

protein-coding   GIFtS: 47
GCID: GC03M039200

Xin Actin-Binding Repeat Containing 1

(Previous name: cardiomyopathy associated 1)
(Previous symbol: CMYA1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Xin Actin-Binding Repeat Containing 11 2     XIN3 5
CMYA11 2 3 5     Xin2
Cardiomyopathy Associated 11 2     Xin Actin-Binding Repeat-Containing Protein 12
Cardiomyopathy-Associated Protein 12 3     

External Ids:    HGNC: 143011   Entrez Gene: 1659042   Ensembl: ENSG000001683347   OMIM: 6097775   UniProtKB: Q702N83   

Export aliases for XIRP1 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for XIRP1 Gene: 
XIRP1 (xin actin-binding repeat containing 1) is a protein-coding gene. Diseases associated with XIRP1 include myofibrillar myopathy, and myopathy. GO annotations related to this gene include actin binding. An important paralog of this gene is XIRP2.

UniProtKB/Swiss-Prot: XIRP1_HUMAN, Q702N8
Function: Protects actin filaments from depolymerization




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_022517.18  NC_018914.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the XIRP1 gene promoter:
         CHOP-10   MyoD   aMEF-2   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidXIRP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for XIRP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat XIRP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p22.2   Ensembl cytogenetic band:  3p22.2   HGNC cytogenetic band: 3p21.33

XIRP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
XIRP1 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M039200:  view genomic region     (about GC identifiers)

Start:
39,224,701 bp from pter      End:
39,234,087 bp from pter
Size:
9,387 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: XIRP1_HUMAN, Q702N8 (See protein sequence)
Recommended Name: Xin actin-binding repeat-containing protein 1  
Size: 1843 amino acids; 198561 Da
Subunit: Interacts with CTNNB1 (By similarity). Interacts with F-actin, FLNC and VASP
Subcellular location: Cell junction. Note=Colocalizes with actin stress fibers
Miscellaneous: 'Xin' means 'heart' in Chinese
Sequence caution: Sequence=BAC86519.1; Type=Erroneous initiation; Sequence=CAC81057.1; Type=Frameshift;
Positions=1594; Sequence=CAD28459.1; Type=Erroneous initiation;
Secondary accessions: A0JP25 A4QPE2 Q68DF2 Q6ZTR3 Q702N9 Q8IVN7 Q8N1N3 Q8N904 Q8TCG7
Alternative splicing: 3 isoforms:  Q702N8-1   Q702N8-2   Q702N8-3   

Explore the universe of human proteins at neXtProt for XIRP1: NX_Q702N8

Explore proteomics data for XIRP1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q702N8

  • XIRP1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    XIRP1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001185550.1  NP_919269.2  

    ENSEMBL proteins: 
     ENSP00000379550   ENSP00000343140   ENSP00000391645  

    Human Recombinant Protein Products for XIRP1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Custom Protein Services for XIRP1
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for XIRP1 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005913cell-cell adherens junction ----
    GO:0005916fascia adherens IEA--
    GO:0014704intercalated disc ----
    GO:0030054cell junction ----

    XIRP1 for ontologies           About GeneDecksing



    XIRP1 Antibody Products: 
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    Novus Biologicals XIRP1 Antibodies
    Abcam antibodies for XIRP1
    Cloud-Clone Corp. Antibodies for XIRP1 
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    Assay Products for XIRP1: 
    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for XIRP1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for XIRP1 
    Cloud-Clone Corp. CLIAs for XIRP1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR012510 Actin-binding_Xin_repeat

    Graphical View of Domain Structure for InterPro Entry Q702N8

    ProtoNet protein and cluster: Q702N8

    1 Blocks protein domain: IPB012510 Actin Binding Sixteen Amino Acid

    UniProtKB/Swiss-Prot: XIRP1_HUMAN, Q702N8
    Domain: Xin repeats bind F-actin
    Similarity: Belongs to the Xin family
    Similarity: Contains 17 Xin repeats


    XIRP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: XIRP1_HUMAN, Q702N8
    Function: Protects actin filaments from depolymerization

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding IEA--
         
    XIRP1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for XIRP1:
     Increased cell number in G2M,  

         3 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Xirp1):
     cardiovascular system  growth/size  muscle 

    XIRP1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for XIRP1: Xirp1tm1Dofr Xirp1tm1Jl

       inGenious Targeting Laboratory - Custom generated mouse model solutions for XIRP1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for XIRP1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for XIRP1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for XIRP1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat XIRP1
    6 QIAGEN miScript miRNA Assays for microRNAs that regulate XIRP1:
    hsa-miR-3678-3p hsa-miR-133a hsa-miR-342-5p hsa-miR-133b hsa-miR-759 hsa-miR-1910
    SwitchGear 3'UTR luciferase reporter plasmidXIRP1 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for XIRP1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat XIRP1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for XIRP1
    Sirion Biotech Customized adenovirus for overexpression of XIRP1

    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for XIRP1 (see all 7)
    OriGene ORF clones in mouse, rat for XIRP1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): XIRP1 (NM_194293)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat XIRP1

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    Search LifeMap BioReagents cell lines for XIRP1
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for XIRP1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for XIRP1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for XIRP1 (Q702N83 ENSP000003431404) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACTA1P681333, ENSP000003556454I2D: score=1 STRING: ENSP00000355645
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008285negative regulation of cell proliferation IEA--
    GO:0030036actin cytoskeleton organization ----
    GO:0042391regulation of membrane potential IEA--
    GO:0045214sarcomere organization IEA--
    GO:0055013cardiac muscle cell development IEA--

    XIRP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for XIRP1

    Search CenterWatch for drugs/clinical trials and news about XIRP1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for XIRP1 gene (2 alternative transcripts): 
    NM_001198621.1  NM_194293.2  

    Unigene Clusters for XIRP1:

    Xin actin-binding repeat containing 1
    Hs.447868  [show with all ESTs], Hs.737550
    Unigene Representative Sequences: AJ626900, AL832459
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000396251(uc003cji.3 uc003cjj.3) ENST00000340369(uc003cjk.2)
    ENST00000421646
    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat XIRP1
    6 QIAGEN miScript miRNA Assays for microRNAs that regulate XIRP1:
    hsa-miR-3678-3p hsa-miR-133a hsa-miR-342-5p hsa-miR-133b hsa-miR-759 hsa-miR-1910
    SwitchGear 3'UTR luciferase reporter plasmidXIRP1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for XIRP1
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    Clone
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    OriGene clones in human, mouse for XIRP1 (see all 7)
    OriGene ORF clones in mouse, rat for XIRP1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): XIRP1 (NM_194293)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for XIRP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat XIRP1
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for XIRP1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat XIRP1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat XIRP1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat XIRP1

    Additional mRNA sequence: 

    AK122723.1 AL831956.1 AL832020.1 AL832459.1 

    5 DOTS entries:

    DT.95345262  DT.453185  DT.100750081  DT.100019592  DT.120911400 

    24/53 AceView cDNA sequences (see all 53):

    AI239637 AW755250 AY375160 AK096421 AJ626900 BF839758 N74291 AJ626899 
    BX116988 AK126299 F36825 AK095941 AL831956 NM_194293 AL596797 W04392 
    BM728386 AL832020 AL596801 BF835132 AJ706929 CR749430 AA885028 BF507675 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for XIRP1    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b
    SP1:                        
    SP2:        -               
    SP3:                        


    ECgene alternative splicing isoforms for XIRP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    XIRP1 expression in normal human tissues (normalized intensities)      XIRP1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACTGTCCCCC
    XIRP1 Expression
    About this image


    XIRP1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Heart (Cardiovascular System)    fully expand to see all 2 entries
             Cardiomyocyte-like progenitor cells ( Derivation of cardiomyocytes from pluripotent...
             heart muscle ; myocytes   
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             vastus lateralis   
     
     Bone (Muscoskeletal System)
             Human Mesenchymal Stem Cell-bone marrow (HMSC-Bone Marrow)   
     
     Blood (Muscoskeletal System)
             Human Mesenchymal Stem Cell-bone marrow (HMSC-Bone Marrow)   
     
     Mesenchymal Stem Cells
             Human Mesenchymal Stem Cell-bone marrow (HMSC-Bone Marrow)   

    See XIRP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for XIRP1

    SOURCE GeneReport for Unigene clusters: Hs.447868 Hs.737550

    UniProtKB/Swiss-Prot: XIRP1_HUMAN, Q702N8
    Tissue specificity: Isoform A, isoform B and isoform C are expressed in heart

        SABiosciences Custom PCR Arrays for XIRP1
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat XIRP1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for XIRP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for XIRP1 gene from 4/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Xirp11 , 5 xin actin-binding repeat containing 11, 5 80.39(n)1
    78.48(a)1
      9 (71.36 cM)5
    224371  NM_011724.31  NP_035854.31 
     1200137555 
    chicken
    (Gallus gallus)
    Aves XIRP16
    xin actin-binding repeat-containing protein 1
    24(a)
    1 ↔ 1
    2(4944068-4977259)
    lizard
    (Anolis carolinensis)
    Reptilia XIRP16
    Uncharacterized protein
    24(a)
    1 ↔ 1
    6(716883-722630)
    zebrafish
    (Danio rerio)
    Actinopterygii xirp16
    CU638714.16
    (see all 3)
    Uncharacterized protein
    (see all 3)
    20(a)
    14(a)
    (see all 3)
    many → 1
    many → 1
    (see all 3)
    2(24106798-24114653)
    24(20439860-20459129)


    ENSEMBL Gene Tree for XIRP1 (if available)
    TreeFam Gene Tree for XIRP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for XIRP1 gene
    XIRP22  

    XIRP1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/494 SNPs in XIRP1 are shown (see all 494)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0384474
    A breast cancer sample4--see VAR_0384472 R K mis40--------
    VAR_0384424
    A breast cancer sample4--see VAR_0384422 L H mis40--------
    rs1450946291,2
    C,Funtested139229856(+) CTCTTC/TGTCCC 4 K E mis11Minor allele frequency- T:0.00NA 4548
    rs1430077251,2
    C--39224456(+) AGCAC-/TGTG  
            
    TGTGT
    2 -- ds5001 int10--------
    rs680428941,2
    C--39224498(-) CCCAT-/CA    
       
    /CACA
    CACAC
    2 -- ds5001 int12NA 4
    rs1383552471,2
    C--39224510(+) GGGAT-/AGGGGC 2 -- ds5001 int10--------
    rs1844540111,2
    --39224592(+) AGCCTG/TCCCAC 2 -- ds5001 int10--------
    rs1893409081,2
    --39224637(+) TTGTGA/GCTGTT 2 -- ds5001 int10--------
    rs1448208731,2
    --39224640(+) GGCTG-/GGTTTTTC 2 -- cds10--------
    rs1812073291,2
    --39224649(+) TCTCCC/TCCTGC 2 -- ds5001 int10--------

    HapMap Linkage Disequilibrium report for XIRP1 (39224701 - 39234087 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for XIRP1: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing XIRP1
    DNA2.0 Custom Variant and Variant Library Synthesis for XIRP1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609777    OMIM disorders: --

    3 diseases for XIRP1:    About MalaCards
    myofibrillar myopathy    myopathy    squamous cell carcinoma


    XIRP1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): XIRP1

    Export disorders for XIRP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for XIRP1 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with XIRP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Xin repeats define a novel actin-binding motif. (PubMed id 15454575)1, 2, 3, 9 Pacholsky D....van der Ven P.F. (2004)
    2. Unusual splicing events result in distinct Xin isoforms that associate differentially with filamin c and Mena/VASP. (PubMed id 16631741)1, 2, 9 van der Ven P.F.M.... Fuerst D.O. (2006)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Localization of the novel Xin protein to the adherens junction complex in cardiac and skeletal muscle during development. (PubMed id 12203715)1, 3 Sinn H.W....Lin J.J. (2002)
    5. Multiple tumor-suppressor genes on chromosome 3p cont ribute to head and neck squamous cell carcinoma tumorigenesis. (PubMed id 20657180)1 Lee D.J....Su G.H. (2010)
    6. Differential involvement of sarcomeric proteins in myofibrillar myopathies: a morphological and immunohistochemical study. (PubMed id 19151983)1 Claeys K.G....FA1rst D.O. (2009)
    7. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    9. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 165904 HGNC: 14301 AceView: CMYA1 Ensembl:ENSG00000168334 euGenes: HUgn165904
    ECgene: XIRP1 H-InvDB: XIRP1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for XIRP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for XIRP1 gene:
    Search GeneIP for patents involving XIRP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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