Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

XG Gene

protein-coding   GIFtS: 47
GCID: GC0XP002663

Xg blood group

(Previous name: Xg blood group (pseudoautosomal boundary-divided on the...)
(Previous symbol: PBDX)
 Explore 13 diseases affiliated with
XG via our new
 Human Malady Compendium 
Biological research products
for XG
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Xg Blood Group1 2
PBDX1 2 3
Xg Blood Group (Pseudoautosomal Boundary-Divided On The X Chromosome)1 2
Glycoprotein Xg2
XG Glycoprotein2
Protein PBDX3

External Ids:    HGNC: 128061   Entrez Gene: 74992   Ensembl: ENSG000001243437   OMIM: 3008795   UniProtKB: P558083   

Export aliases for XG gene to outside databases

Previous GC identifers: GC0XU990234 GC0XM001839 GC0XP002200 GC0XP002265


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for XG:
This gene encodes the XG blood group antigen, and is located at the pseudoautosomal boundary on the short (p) arm of
chromosome X. The three 5' exons reside in the pseudoautosomal region and the remaining exons within the X-specific
end. A truncated copy of this gene is found on the Y chromosome at the pseudoautosomal boundary. It is transcribed,
but not expected to make a Y-chromosome specific gene product. Alternatively spliced transcript variants encoding
different isoforms have been found for this gene. (provided by RefSeq, Nov 2008)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.1  NT_167197.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the XG gene promoter:
         NF-1/L   NF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidXG promoter sequence
   Search SABiosciences Chromatin IP Primers for XG

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat XG


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp22.33   Ensembl cytogenetic band:  Xp22.33   HGNC cytogenetic band: Xp22.32

XG Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
XG gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP002663:  view genomic region     (about GC identifiers)

Start:
2,670,091 bp from pter      End:
2,734,541 bp from pter
Size:
64,451 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: XG_HUMAN, P55808 (See protein sequence)
Recommended Name: Glycoprotein Xg precursor  
Size: 180 amino acids; 19723 Da
Subcellular location: Cell membrane; Single-pass type I membrane protein
Miscellaneous: The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y
chromosomes
Secondary accessions: E9PCH1 Q496N8 Q496N9 Q496P0 Q71BZ5
Alternative splicing: 3 isoforms:  P55808-1   P55808-2   P55808-3   (No experimental confirmation available. Ref.5 (AAI00766) sequence is in conflict in position: 131:L->P)

Explore the universe of human proteins at neXtProt for XG: NX_P55808

Post-translational modifications:

  • O-glycosylated (Probable)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P55808

  • XG Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001135391.1  NP_001135392.1  NP_780778.1  

    ENSEMBL proteins: 
     ENSP00000370566   ENSP00000411004   ENSP00000430005   ENSP00000398503  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom Protein Services for XG 
    GenScript Custom Purified and Recombinant Proteins Services for XG
    Novus Biologicals XG Protein
    Novus Biologicals XG Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for XG

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005887integral to plasma membrane IDA7533029


    XG for ontologies           About GeneDecksing



    XG Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    R&D Systems Antibodies for XG
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for XG 
    GenScript Custom Superior Antibodies Services for XG
    Novus Biologicals XG Antibodies
    Search for Antibodies for XG at Abcam  
    Uscn Antibodies for XG
    Search ThermoFisher Antibodies for XG

    Assay Products for XG: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for XG
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for XG


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    XG for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR022078 CD99L2

    Graphical View of Domain Structure for InterPro Entry P55808

    ProtoNet protein and cluster: P55808

    UniProtKB/Swiss-Prot: XG_HUMAN, P55808
    Similarity: Belongs to the CD99 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    miRNA
    Products:
        
    OriGene 3'-UTR Clone (see all 3): XG
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat XG
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate XG
    SwitchGear 3'UTR luciferase reporter plasmidXG 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for XG
    OriGene shRNA RFP: XG
    OriGene siRNA: XG
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat XG

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for XG

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for XG (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for XG (see all 3)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: XG (NM_005249)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for XG
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat XG 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for XG
    Search LifeMap BioReagents cell lines for XG

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for XG

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--


    XG for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for XG

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--


    XG for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for XG
    Search CenterWatch for drugs/clinical trials and news about XG 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for XG gene (3 alternative transcripts): 
    NM_001141919.1  NM_001141920.1  NM_175569.2  

    Unigene Cluster for XG:

    Xg blood group
    Hs.179675  [show with all ESTs]
    Unigene Representative Sequence: NM_001141919
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000381174 ENST00000419513(uc010ndb.2) ENST00000509484 ENST00000503018
    ENST00000519244 ENST00000426774(uc004cqp.3 uc011mhg.2)

    miRNA
    Products:
         
    OriGene 3'-UTR Clone (see all 3): XG
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat XG
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate XG
    SwitchGear 3'UTR luciferase reporter plasmidXG 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for XG
    OriGene shRNA RFP: XG
    OriGene siRNA: XG
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat XG
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for XG (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for XG (see all 3)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: XG (NM_005249)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for XG
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat XG 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for XG
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat XG
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat XG
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat XG

    Additional cDNA sequence: 

    AF380356.1 AF534880.1 AK304164.1 BC100764.2 BC100765.2 BC100766.2 BC100767.1 NR_003254.1 
    Z48517.1 Z48518.1 Z48519.1 

    14 DOTS entries:

    DT.97835036  DT.121282475  DT.431733  DT.121282484  DT.300477  DT.95133671  DT.121282487  DT.100643907 
    DT.121282478  DT.40258841  DT.120652297  DT.308496  DT.91918877  DT.97782142 

    24/40 AceView cDNA sequences (see all 40):

    CD172101 CA390062 BX098030 BF515810 BX379565 AA336889 NM_175569 AI168338 
    AF380356 Z48518 T96594 BU626184 BF718591 AW369156 AW449679 AI183456 
    BX403244 BM723344 BX107166 BQ014345 H63758 BF507402 AA708174 BE693663 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    XG expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AGCTTAATTA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See XG Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for XG

    SOURCE GeneReport for Unigene cluster: Hs.179675

    UniProtKB/Swiss-Prot: XG_HUMAN, P55808
    Tissue specificity: Expressed in erythroid tissues, including thymus, bone marrow and fetal liver, and in several
    nonerythroid tissues, such as heart, placenta, skeletal muscle, thyroid and trachea, as well as in skin fibroblasts.
    Expression is low or undetectable in other tissues

        SABiosciences Custom PCR Arrays for XG
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for XG
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat XG
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat XG
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat XG
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for XG

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for XG gene from 1/3 species (see all 3)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves XG6
    Uncharacterized protein
    38(a)
    1 ↔ 1
    1(132633051-132655159)
            Species with no ortholog for XG

    ENSEMBL Gene Tree for XG (if available)
    TreeFam Gene Tree for XG (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for XG gene

    XG for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for XG
    PGOHUM00000233746


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    UniProtKB/Swiss-Prot: XG_HUMAN, P55808
    Polymorphism: XG is responsible for the Xg blood group system


    10/11409 NCBI SNPs in XG are shown (see all 11409    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs3111651,2
    C,F,A,H,--2699555(+) CATATA/CTCCAC 3 -- int16Minor allele frequency- C:0.40NA WA CSA 10
    rs1860099751,2
    --2699559(+) TCTCCA/GCATAG 3 -- int10--------
    rs66550381,2
    C,--2699625(+) tttccA/Gggcct 3 -- int10--------
    rs285794191,2
    C,--2699645(+) AACAGG/TTTGCA 3 -- int10--------
    rs600754871,2
    C,--2699676(+) CCCCAA/GTTCAT 3 -- int14Minor allele frequency- G:0.14WA CSA 7
    rs1480347301,2
    --2699683(+) TCATCA/GGTGTT 3 -- int10--------
    rs1908190591,2
    --2699739(+) CAGAAC/GGTTTG 3 -- int10--------
    rs1995041331,2
    --2699898(+) AAACC-/TTTTTT 3 -- int10--------
    rs32149871,2
    --2699899(-) AAAAA-/AGGTTT 3 -- int1 trp30--------
    rs602337601,2
    C--2699899(+) TTTTT-/TAAGTT 3 -- int10--------

    HapMap Linkage Disequilibrium report for XG (2670091 - 2734541 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 8 variations for XG
         8 CNVs: 3260 34412 8293 4142 8291 52978 8292 23329
    Locus Specific Mutation Databases (LSDB): XG
    Blood Group Antigen Gene Mutation Database (BGMUT) blood group system

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing XG
    DNA2.0 Custom Variant and Variant Library Synthesis for XG

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    XG for disorders           About GeneDecksing

    OMIM gene information: 300879    OMIM disorders: --

    13 diseases for XG:    About MalaCards
    x-linked ichthyosis    glucosephosphate dehydrogenase deficiency    chondrodysplasia punctata    color blindness
    ocular albinism    anosmia    chondrodysplasia    ichthyosis
    kallmann syndrome    hypogonadotropism    albinism    hypogonadism
    blindness

    4 diseases from the University of Copenhagen DISEASES database for XG:
    Color blindness     X-linked ichthyosis     Ocular albinism     Glucosephosphate dehydrogenase deficiency
    Genatlas disease: XG
    Xg blood group


    Export disorders for XG gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for XG gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with XG)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning of PBDX, an MIC2-related gene that spans the pseudoautosomal boundary on chromosome Xp. (PubMed id 8054981)1, 2, 3 Ellis N.A.... Weller P. (1994)
    2. A study of the coregulation and tissue specificity of XG and MIC2 gene expression in eukaryotic cells. (PubMed id 10688843)1, 2 Fouchet C....Lopez C. (2000)
    3. PBDX is the XG blood group gene. (PubMed id 7533029)1, 2 Ellis N.A....Banting G. (1994)
    4. Quantitative analysis of XG blood group and CD99 antigens on human red cells. (PubMed id 10941840)1, 9 Fouchet C....Lopez C. (2000)
    5. [Xg gene frequencies in Tunisia] (PubMed id 18789743)1 Gandouz R....Skouri H. (2008)
    6. The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (2005)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    9. The human Y chromosome homologue of XG: transcription of a naturally truncated gene. (PubMed id 7633446)1 Weller P.A....Ellis N.A. (1995)
    10. X-linked ichthyosis, due to steroid sulphatase deficiency, associated with Kallmann syndrome (hypogonadotropic hypogonadism and anosmia): linkage relationships with Xg and cloned DNA sequences from the distal short arm of the X chromosome. (PubMed id 3007328)1 Ballabio A....Andria G. (1986)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7499 HGNC: 12806 AceView: XG Ensembl:ENSG00000124343 euGenes: HUgn7499
    ECgene: XG H-InvDB: XG

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for XG Pharmacogenomics, SNPs, Pathways
    dbRBC/BGMUThttp://www.ncbi.nlm.nih.gov/gv/mhc/xslcgi.cgi?cmd=bgmut/systems_info&system=xg

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for XG gene:
    Search GeneIP for patents involving XG

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Antibodies for XG (Xg)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for XG  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for XG   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for XG  
     Browse OriGene Protein Over-expression Lysates   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for XG   OriGene 3'-UTR Clone for XG  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for XG   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for XG  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for XG   OriGene Custom Protein Services for XG  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat XG
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing XG
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat XG
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat XG
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat XG
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat XG
     GenScript Custom Purified and Recombinant Proteins Services for XG GenScript cDNA clones with any tag delivered in your preferred vector for XG
     GenScript Custom Assay Services for XG GenScript Custom Superior Antibodies Services for XG
     GenScript Custom overexpressing Cell Line Services for XG CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in XG promoter
     Search Chromatin IP Primers for XG
     RT2 qPCR Primer Assay in human, mouse / rat XG
     GNC Network for XG
     SABiosciences Custom PCR Arrays for XG
     Search Tocris compounds for XG
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     XG antibodies
     XG proteins
     XG lysates
     Search for Antibodies for XG at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for XG
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     XG Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for XG
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for XG
     SwitchGear 3'UTR luciferase reporter plasmids for XG
     SwitchGear Promoter luciferase reporter plasmids for XG
     Search ThermoFisher Antibodies for XG
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat XG
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      XG gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4