Aliases for XCR1 Gene
External Ids for XCR1 Gene
Previous Symbols for XCR1 Gene
The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for XCR1 Gene
XCR1 (Chemokine (C Motif) Receptor 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Akt Signaling. GO annotations related to this gene include chemokine receptor activity. An important paralog of this gene is CCR7.
UniProtKB/Swiss-Prot for XCR1 Gene
Receptor for chemokines SCYC1 and SCYC2. Subsequently transduces a signal by increasing the intracellular calcium ions level