Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

XCL2 Gene

protein-coding   GIFtS: 47
GCID: GC01M168510

Chemokine (C Motif) Ligand 2

(Previous names: small inducible cytokine subfamily C, member 2)
(Previous symbol: SCYC2)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Chemokine (C Motif) Ligand 21 2     XC Chemokine Ligand 22 3
SCYC21 2 3 5     SCM1B2 5
Small Inducible Cytokine Subfamily C, Member 21 2     SCM-1b2
C Motif Chemokine 22 3     Cytokine SCM-1 Beta2

External Ids:    HGNC: 106461   Entrez Gene: 68462   Ensembl: ENSG000001431857   OMIM: 6048285   UniProtKB: Q9UBD33   

Export aliases for XCL2 gene to outside databases

Previous GC identifers: GC01M166145 GC01M164161 GC01M165206 GC01M165697 GC01M165242 GC01M166776 GC01M139756


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for XCL2 Gene: 
XCL2 (chemokine (C motif) ligand 2) is a protein-coding gene. Diseases associated with XCL2 include osteoarthritis, and tuberculosis, and among its related super-pathways are Chemokine signaling pathway and Signaling by GPCR. GO annotations related to this gene include chemokine activity. An important paralog of this gene is XCL1.

UniProtKB/Swiss-Prot: XCL2_HUMAN, Q9UBD3
Function: Chemotactic activity for lymphocytes but not for monocytes or neutrophils (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the XCL2 gene promoter:
         SRF   HFH-3   C/EBPbeta   AML1a   E47   GATA-2   FOXI1   c-Myb   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for XCL2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat XCL2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q24.2   Ensembl cytogenetic band:  1q24.2   HGNC cytogenetic band: 1q24.2

XCL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
XCL2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M168510:  view genomic region     (about GC identifiers)

Start:
168,510,003 bp from pter      End:
168,513,235 bp from pter
Size:
3,233 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: XCL2_HUMAN, Q9UBD3 (See protein sequence)
Recommended Name: Cytokine SCM-1 beta precursor  
Size: 114 amino acids; 12567 Da
Subcellular location: Secreted

Explore the universe of human proteins at neXtProt for XCL2: NX_Q9UBD3

Explore proteomics data for XCL2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9UBD3

  • XCL2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    XCL2 Protein Expression
    REFSEQ proteins: NP_003166.1  
    ENSEMBL proteins: 
     ENSP00000356793  
    Reactome Protein details: Q9UBD3
    Human Recombinant Protein Products for XCL2: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for XCL2
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for XCL2
    GenScript Custom Purified and Recombinant Proteins Services for XCL2
    Novus Biologicals XCL2 Lysate
    Sino Biological Recombinant Protein for XCL2
    Sino Biological Cell Lysate for XCL2 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for XCL2 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005615extracellular space IEA--

    XCL2 for ontologies           About GeneDecksing



    XCL2 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for XCL2
    GenScript Custom Superior Antibodies Services for XCL2
    Search for Antibodies for XCL2 at Abcam
    Cloud-Clone Corp. Antibodies for XCL2 
    Search ThermoFisher Antibodies for XCL2
    Search LSBio for Antibodies for XCL2 

    Assay Products for XCL2: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for XCL2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for XCL2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for XCL2 
    Cloud-Clone Corp. CLIAs for XCL2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ENDOLIG: Endogenous ligands

    2 InterPro protein domains:
     IPR001811 Chemokine_IL8-like_dom
     IPR008105 Chemokine_XCL1

    Graphical View of Domain Structure for InterPro Entry Q9UBD3

    ProtoNet protein and cluster: Q9UBD3

    1 Blocks protein domain: IPB008105 Lymphotactin precursor signature

    UniProtKB/Swiss-Prot: XCL2_HUMAN, Q9UBD3
    Similarity: Belongs to the intercrine gamma family


    XCL2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: XCL2_HUMAN, Q9UBD3
    Function: Chemotactic activity for lymphocytes but not for monocytes or neutrophils (By similarity)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008009chemokine activity IEA--
         
    XCL2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for XCL2:
     Decreased viability 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for XCL2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for XCL2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for XCL2 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for XCL2 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat XCL2
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate XCL2
    SwitchGear 3'UTR luciferase reporter plasmidXCL2 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for XCL2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat XCL2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for XCL2
    Sirion Biotech Customized adenovirus for overexpression of XCL2

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for XCL2 (see all 6)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: XCL2 (NM_002089)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for XCL2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat XCL2
    Sirion Biotech Customized lentivirus for stable overexpression of XCL2 
                         Customized lentivirus expression plasmids for stable overexpression of XCL2 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for XCL2
    Search LifeMap BioReagents cell lines for XCL2
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for XCL2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for XCL2 About   (see all 7)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Chemokine Signaling
    Chemokine Signaling0.33
    Chemokine signaling pathway0.33
    2Signaling by GPCR
    Signaling by GPCR0.90
    Signal Transduction0.55
    GPCR downstream signaling0.90
    3Class A/1 (Rhodopsin-like receptors)
    Class A/1 (Rhodopsin-like receptors)0.71
    Peptide ligand-binding receptors0.60
    GPCR ligand binding0.71
    4G alpha (q) signalling events
    Gastrin-CREB signalling pathway via PKC and MAPK0.90
    G alpha (q) signalling events0.90
    5PEDF Induced Signaling
    Cytokine-cytokine receptor interaction0.43

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for XCL2
        Chemokine Signaling
    Transendothelial Migration of Leukocytes


    5/9        Reactome Pathways for XCL2 (see all 9)
        GPCR downstream signaling
    Peptide ligand-binding receptors
    Gastrin-CREB signalling pathway via PKC and MAPK
    Signaling by GPCR
    GPCR ligand binding


    2         Kegg Pathways  (Kegg details for XCL2):
        Cytokine-cytokine receptor interaction
    Chemokine signaling pathway


    XCL2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for XCL2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

    5/18 Interacting proteins for XCL2 (Q9UBD33 ENSP000003567934) via UniProtKB, MINT, STRING, and/or I2D (see all 18)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    XCR1P460943, ENSP000003104054I2D: score=1 STRING: ENSP00000310405
    CCR1ENSP000002961404STRING: ENSP00000296140
    CCR10ENSP000003325044STRING: ENSP00000332504
    CCR2ENSP000002923014STRING: ENSP00000292301
    CCR3ENSP000003500034STRING: ENSP00000350003
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006935chemotaxis IEA--
    GO:0006955immune response IEA--
    GO:0007165signal transduction TAS7875320
    GO:0008015blood circulation TAS7875320

    XCL2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for XCL2

    Search CenterWatch for drugs/clinical trials and news about XCL2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for XCL2 gene: 
    NM_003175.3  

    Unigene Cluster for XCL2:

    Chemokine (C motif) ligand 2
    Hs.458346  [show with all ESTs]
    Unigene Representative Sequence: BC070308
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000367819(uc001gfn.4)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat XCL2
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate XCL2
    SwitchGear 3'UTR luciferase reporter plasmidXCL2 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for XCL2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat XCL2
    Clone
    Products:
         
    OriGene clones in human, mouse for XCL2 (see all 6)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: XCL2 (NM_002089)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for XCL2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat XCL2
    Sirion Biotech Customized lentivirus for stable overexpression of XCL2 
                         Customized lentivirus expression plasmids for stable overexpression of XCL2 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for XCL2
    OriGene qSTAR qPCR primer pairs in human, mouse for XCL2
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat XCL2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat XCL2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat XCL2

    Additional mRNA sequence: 

    BC069360.1 BC070308.1 

    4 DOTS entries:

    DT.100735017  DT.305525  DT.109036  DT.91854396 

    14 AceView cDNA sequences:

    NM_003175 BC069360 AI057377 CD521967 U23772 BC070308 BE218461 AW467190 
    AW050525 AA650495 AA420635 AI821666 AA420679 AI915168 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    XCL2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    XCL2 Expression
    About this image


    See XCL2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for XCL2

    SOURCE GeneReport for Unigene cluster: Hs.458346
        SABiosciences Expression via Pathway-Focused PCR Array including XCL2: 
              Chemokines & Receptors in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for XCL2
    OriGene qSTAR qPCR primer pairs in human, mouse for XCL2
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat XCL2
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat XCL2
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat XCL2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for XCL2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for XCL2 gene from 1/7 species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves SCYC16
    lymphotactin precursor
    29(a)
    1 → many
    1(83400070-83404445)
            Species with no ortholog for XCL2

    ENSEMBL Gene Tree for XCL2 (if available)
    TreeFam Gene Tree for XCL2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for XCL2 gene
    XCL12  
    14 SIMAP similar genes for XCL2 using alignment to 1 protein entry:     XCL2_HUMAN:
    XCL1    CCL8    CCL13    CCL11    CCL3L1    CCL3L3
    CCL26    CCL14    CCL24    CCL4L1    CCL4L2    LOC728835
    CCL7    MCP-3

    XCL2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/212 SNPs in XCL2 are shown (see all 212)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1822698671,2
    C--168509524(+) CACCAA/GAATAA 1 -- int10--------
    rs4707331,2
    C,F,A,H--168510122(-) CTGAGT/ATTATA 1 -- ut311Minor allele frequency- A:0.48MN 184
    rs1869362671,2
    --168510195(+) CTAGCC/TAGTCA 2 S G mis10--------
    rs1493724181,2
    F--168510202(+) GTCAGG/AGTCAC 2 /T syn11Minor allele frequency- A:0.00NA 4552
    rs1485006451,2
    C--168510213(+) AGCTGT/AATTGG 2 /T /S mis11Minor allele frequency- A:0.00NA 4552
    rs1926449151,2
    C--168510254(+) GGATCA/GTGTTA 2 T M mis10--------
    rs1439518661,2
    C,F--168510297(+) GACCAC/TGTCTC 2 M V mis12Minor allele frequency- T:0.00NA EU 5873
    rs6697531,2
    C,F,A,H--168510310(-) GCCACA/GTGGGT 2 T syn1 ese35Minor allele frequency- G:0.05EA NS NA 302
    rs1179520251,2
    C--168510314(+) ACGTGC/G/TCTTGT 3 D A G mis11EA 120
    rs1126743941,2
    C,F--168510366(+) GTAACG/ACAAGG 1 -- int12Minor allele frequency- A:0.00CSA EU 1325

    HapMap Linkage Disequilibrium report for XCL2 (168510003 - 168513235 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for XCL2: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing XCL2
    DNA2.0 Custom Variant and Variant Library Synthesis for XCL2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604828    OMIM disorders: --

    2 diseases for XCL2:    About MalaCards
    osteoarthritis    tuberculosis


    XCL2 for disorders           About GeneDecksing


    Export disorders for XCL2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for XCL2 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with XCL2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (2004)
    4. Structure and expression of two highly related genes encoding SCM- 1/human lymphotactin. (PubMed id 8849694)1, 2 Yoshida T....Yoshie O. (1996)
    5. Molecular cloning of a novel C or gamma type chemokine, SCM-1. (PubMed id 7875320)1, 3 Yoshida T.... Yoshie O. (1995)
    6. Mycobacterium tuberculosis antigen Wag31 induces expression of C-chemokine XCL2 in macrophages. (PubMed id 18618175)1 Cao W....Lu H. (2008)
    7. Association of the -2510A/G chemokine (C-C motif) ligand 2 polymorphism with knee osteoarthritis in a Korean population. (PubMed id 17763208)1 Park H.J....Hong S.J. (2007)
    8. Stable association between G alpha(q) and phospholipase C beta 1 in living cells. (PubMed id 16754659)1 Dowal L....Scarlata S. (2006)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. The sequence of the human genome. (PubMed id 11181995)1 Venter J.C.... Zhu X. (2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6846 HGNC: 10646 AceView: XCL2 Ensembl:ENSG00000143185 euGenes: HUgn6846
    ECgene: XCL2 Kegg: 6846 H-InvDB: XCL2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for XCL2 Pharmacogenomics, SNPs, Pathways
    Wikipedia http://en.wikipedia.org/wiki/XCL2

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for XCL2 gene:
    Search GeneIP for patents involving XCL2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for XCL2  
     OriGene qPCR primer pairs and template standards for XCL2   OriGene Protein Over-expression Lysate for XCL2  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for XCL2  
     OriGene qSTAR qPCR primer pairs in human, mouse for XCL2   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for XCL2   OriGene Custom Protein Services for XCL2  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat XCL2
     QIAGEN SeqTarget long-range PCR primers for resequencing XCL2
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat XCL2
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat XCL2
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat XCL2
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat XCL2
     GenScript Custom Purified and Recombinant Proteins Services for XCL2 GenScript cDNA clones with any tag delivered in your preferred vector for XCL2
     GenScript Custom Assay Services for XCL2 GenScript Custom Superior Antibodies Services for XCL2
     GenScript Custom overexpressing Cell Line Services for XCL2 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in XCL2 promoter
     Search Chromatin IP Primers for XCL2
     RT2 qPCR Primer Assay in human, mouse / rat XCL2
     Search GNC Networks for XCL2
     SABiosciences PCR Arrays including human, mouse / rat XCL2
     Search Tocris compounds for XCL2
     Proteins and Antibodies for XCL2
     Cell Lysates for XCL2
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     XCL2 lysates
     Search for Antibodies for XCL2 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for XCL2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for XCL2
     Antibodies for XCL2
     ELISAs for XCL2
     CLIAs for XCL2
     Search LifeMap BioReagents cell lines for XCL2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for XCL2
     SwitchGear 3'UTR luciferase reporter plasmids for XCL2
     Browse SwitchGear Promoter luciferase reporter plasmids for XCL2
     Search ThermoFisher Antibodies for XCL2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat XCL2
     inGenious Targeting Laboratory - Custom generated mouse model solutions for XCL2
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for XCL2
    Customized:
     lentivirus for stable overexpression of XCL2
     lentivirus expression plasmids for stable overexpression of XCL2
     adenovirus for overexpression of XCL2
     Search LSBio for Antibodies for XCL2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      XCL2 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4