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Aliases & Descriptions for XAGE5
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| CT12.5 1, 2, 3 | | GAGED5 2, 3 | | MGC119799 2 | | MGC119800 2 | | OTTHUMP00000023321 2 | | XAGE-5 1, 2 |
| | | Descriptions |
|---|
| Cancer/testis antigen 12.5 3 | | G antigen, family D, 5 1, 2 | | Protein XAGE-5 3 | | X antigen family, member 5 2 | | cancer/testis antigen family 12, member 5 2 |
|
| | Search outside databases for aliases for XAGE5 genePrevious GC identifer: GC0XP052726 |
Summaries for XAGE5(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| EntrezGene summary for XAGE5: This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. [provided by RefSeq] UniProtKB/Swiss-Prot: GAGD5_HUMAN, Q8WWM1Function: Unknown |
Genomic Location for XAGE5
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the XAGE5 gene 
Entrez Gene cytogenetic band: Xp11.22 Ensembl cytogenetic band: Xp11.22 HGNC cytogenetic band: Xp11.23XAGE5 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP052857:
(about GC identifiers)
Start:
|
52,857,953 bp from pter |
End:
|
52,864,050 bp from pter |
Size:
|
6,098 bases |
Orientation:
|
plus strand |
RefSeq DNA sequence:- NC_000023.9 NT_011630.14
| Proteins for XAGE5
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: GAGD5_HUMAN, Q8WWM1 (See
protein sequence)Recommended Name: G antigen family D member 5 Size: 108 amino acids; 12077 Da
Secondary accessions: Q5JS81REFSEQ proteins: NP_570131.1
ENSEMBL proteins: ENSP00000364653 ENSP00000364651 ENSP00000342240
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
Antibodies for XAGE5: Assays for XAGE5: | Protein
Domains/ Families for XAGE5(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q8WWM1
ProtoNet protein and cluster: Q8WWM1 1 Blocks protein family: IPB008625 GAGE
UniProtKB/Swiss-Prot: GAGD5_HUMAN, Q8WWM1Similarity: Belongs to the GAGE family | Gene Function for XAGE5
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_130775
Applied Biosystems Silencer® siRNAs for XAGE5
Sigma-Aldrich siRNA for XAGE5  Sigma-Aldrich shRNA for XAGE5  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_130775                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_130775                                  untagged cDNA clone in CMV expression vector: NM_130775 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_130775
UniProtKB/Swiss-Prot: GAGD5_HUMAN, Q8WWM1Function: Unknown | Pathways & Interactions for XAGE5
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| -- |
Drugs & Compounds for XAGE5(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for XAGE5
|
Transcripts for XAGE5(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_130775
Sigma-Aldrich siRNA for XAGE5  Sigma-Aldrich shRNA for XAGE5  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_130775 REFSEQ mRNAs for XAGE5 gene: NM_130775.2
Applied Biosystems TaqMan ® Gene Expression Assays: NM_130775               OriGene GFP tagged cDNA clone in CMV expression vector: NM_130775                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_130775                                  untagged cDNA clone in CMV expression vector: NM_130775  Additional cDNA sequence: BC069129.1 BC103962.1 BC103963.1 BC103964.1 2 DOTS entries: DT.121305250 DT.99947034 3 AceView cDNA sequences:NM_130775 BC069129 AI123309
highest scoring ESTs for XAGE5:BC069129 AI123309 NM_130775 BC103962 BC103963 BC103964 CR747243 Unigene Cluster for XAGE5: X antigen family, member 5 Hs.356874 [show with all ESTs]Unigene Representative Sequence: BC103962
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for XAGE5
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | |
| SP1: | |   | |   | |   | - |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | - |   | - |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   |
About this scheme
ECgene alternative splicing isoforms for XAGE5
3 Ensembl transcripts including schematic representations: ENST00000375503
ENST00000375501
ENST00000351072
|
Expression for XAGE5
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| XAGE5 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for XAGE5
1 Data from GNF BioGPS About these images About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.356874
|
Orthologs for XAGE5
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
| ENSEMBL Gene Tree for XAGE5 | Paralogs for XAGE5(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for XAGE5 gene
- XAGE32 GAGE2D2 GAGE102 GAGE12H2 ENSG000001691642 XAGE2B2 GAGE12C2 GAGE12E2
- GAGE2E2 GAGE12 GAGE2C2 GAGE12F2 GAGE132 PAGE12 XAGE22 GAGE12G2
- GAGE2B2 GAGE2A2 GAGE12J2
|
SNPs/Variants for XAGE5(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for XAGE5 (up to first 250kb)
|
Disorders & Mutations for XAGE5
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
| -- |
Medical News for XAGE5(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for XAGE5 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 4 PubMed articles for XAGE5 gene: |
Search for XAGE5
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing XAGE5
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing XAGE5
(According to HUGE)
About This Section
| -- |
Specialized Databases showing XAGE5(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for XAGE5(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for XAGE5:

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GeneCards Homepage - Last full update: 2 Jul 2009
Incremental update: 13 Oct 2009
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