XAGE2B Gene
protein-coding GIFtS: 32
GCID: GC0XP052112
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X antigen family, member 2B
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Aliases
for XAGE2B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| X Antigen Family, Member 2B1 2 | | Cancer/Testis Antigen 12.22 3 | | Protein XAGE-22 3 | | CT12.22 3 | | G Antigen Family D Member 32 | | GAGED33 |
Export aliases for XAGE2B gene to outside databasesPrevious GC identifers: GC00U922420 GC0XP052130 |
Summaries
for XAGE2B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for XAGE2B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the XAGE2B gene promoter:
NF-1 PPAR-gamma1 PPAR-gamma2 Evi-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for XAGE2B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat XAGE2B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xp11.22 Ensembl cytogenetic band: Xp11.22 HGNC cytogenetic band: Xp11.22XAGE2B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP052112: view genomic region
(about GC identifiers)
Start:
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52,112,173 bp from pter |
End:
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52,118,823 bp from pter |
Size:
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6,651 bases |
Orientation:
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plus strand |
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Proteins
for XAGE2B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: GAGD3_HUMAN, Q96GT9 (See
protein sequence)Recommended Name: G antigen family D member 3 Size: 111 amino acids; 12354 Da
Secondary accessions: Q5HYR4Explore the universe of human proteins at neXtProt for XAGE2B: NX_Q96GT9
XAGE2B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001073006.1
ENSEMBL proteins: ENSP00000286049
Human Recombinant Protein Products:
XAGE2B Antibody Products:
Assay Products for XAGE2B: |
Protein
Domains /
Families
for XAGE2B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
XAGE2B for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96GT9ProtoNet protein and cluster: Q96GT9 1 Blocks protein family: IPB008625 GAGE
UniProtKB/Swiss-Prot: GAGD3_HUMAN, Q96GT9Similarity: Belongs to the GAGE family |
Function
for XAGE2B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for XAGE2B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for XAGE2B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: XAGE2B (NM_001079538) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for XAGE2B | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat XAGE2B |
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Pathways & Interactions
for XAGE2B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for XAGE2B
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for XAGE2B (Q96GT92, 3 ENSP000002860494) via UniProtKB, MINT, STRING, and/or I2DAbout this table
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Drugs & Compounds
for XAGE2B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for XAGE2B
Search CenterWatch for drugs/clinical trials and news about XAGE2B / GAGD3
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Transcripts
for XAGE2B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for XAGE2B gene: NM_001079538.1 1 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000286049(uc004dqe.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for XAGE2B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for XAGE2B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: XAGE2B (NM_001079538) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for XAGE2B | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat XAGE2B |
GeneLoc Exon Structure
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Expression
for XAGE2B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| XAGE2B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTCACTGGGC
About this image
See XAGE2B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for XAGE2B
SABiosciences Custom PCR Arrays for XAGE2B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for XAGE2B
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat XAGE2B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat XAGE2B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat XAGE2B |
Orthologs
for XAGE2B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for XAGE2B (if available)
TreeFam Gene Tree for XAGE2B (if available) |
Paralogs
for XAGE2B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for XAGE2B gene
- PAGE22 GAGE2D2 GAGE42 XAGE32 GAGE102 GAGE12H2 GAGE12I2 PAGE32
- XAGE52 PAGE52 GAGE12C2 GAGE12E2 GAGE12D2 PAGE2B2 GAGE12 GAGE2E2
- GAGE2C2 GAGE12F2 PAGE12 GAGE132 XAGE22 GAGE12G2 GAGE2A2 GAGE2B2
- PAGE42 GAGE12J2
18/31 SIMAP similar genes for XAGE2B using alignment to 1 protein entry: GAGD3_HUMAN(see all similar genes):XAGE3 XAGE5 XAGE-4 PAGE3 GAGE2D GAGE2E
GAGE8 GAGE13 GAGE2A GAGE2B GAGE2C GAGE5
GAGE6 PAGE2 PAGE2B GAGE4 GAGE10 GAGE12B
XAGE2B for paralogs About GeneDecksing
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Genomic Variants
for XAGE2B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for XAGE2B (52112173 - 52118823 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for XAGE2B: -- | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for XAGE2B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
XAGE2B for disorders About GeneDecksing
3  diseases for XAGE2B: About MalaCardshydrocele sarcoma melanoma
1 disease from the University of Copenhagen DISEASES database for XAGE2B:Hydrocele Export disorders for XAGE2B gene to outside databases
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Publications
for XAGE2B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for XAGE2B gene integrated from 9 sources:
(articles sorted by number of sources associating them with XAGE2B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The XAGE family of cancer/testis-associated genes: alignment and expression profile in normal tissues, melanoma lesions and Ewing's sarcoma. (PubMed id 11992404)1, 2 Zendman A.J.W....van Muijen G.N.P. (2002)
- Novel genes in the PAGE and GAGE family of tumor antigens found by homology walking in the dbEST database. (PubMed id 10197611)1, 2 Brinkmann U.... Pastan I. (1999)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- The sequence of the human genome. (PubMed id 11181995)1 Venter J.C.... Zhu X. (2001)
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External Searches for XAGE2B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing XAGE2B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing XAGE2B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing XAGE2B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for XAGE2B | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for XAGE2B gene:
Search GeneIP for patents involving XAGE2B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for XAGE2B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for XAGE2B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for XAGE2B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for XAGE2B | | | OriGene Protein Over-expression Lysate for XAGE2B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for XAGE2B | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for XAGE2B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for XAGE2B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for XAGE2B | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for XAGE2B | | OriGene Custom Protein Services for XAGE2B | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat XAGE2B | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing XAGE2B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat XAGE2B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat XAGE2B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat XAGE2B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat XAGE2B |
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| | | | Search Tocris compounds for XAGE2B |
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 | | | | |  |  |  | | | | Search ThermoFisher Antibodies for XAGE2B |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat XAGE2B |
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