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Aliases &
Descriptions
for XAGE2
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases |
|---|
| CT12.2 1, 2, 3 | | GAGED3 2, 3 | | OTTHUMP00000023313 2 | | XAGE-2 1, 2 |
| | | Descriptions |
|---|
| Cancer/testis antigen 12.2 3 | | G antigen, family D, 3 1, 2 | | Protein XAGE-2 3 | | X antigen family, member 2 2 | | XAGE-2 protein 2 | | cancer/testis antigen family 12, member 2 2 |
|
| |
Search outside databases for aliases for XAGE2 genePrevious GC identifer: GC0XP051946 |
Summaries
for XAGE2(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| EntrezGene summary for XAGE2:
This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are
expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly
expressed in normal testis, and in Ewing's sarcoma, rhabdomyosarcoma, a breast cancer and a
germ cell tumor. The protein encoded by this gene shares a sequence similarity with other
GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein
also belongs to a family of CT (cancer-testis) antigens. [provided by RefSeq]
UniProtKB/Swiss-Prot: GAGD3_HUMAN, Q96GT9Function: Unknown |
Genomic Location
for XAGE2
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences)
About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xp11.22 Ensembl cytogenetic band: Xp11.22 HGNC cytogenetic band: Xp11.22-p11.21XAGE2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM052397:
(about GC identifiers)
Start:
|
52,397,076 bp from pter |
End:
|
52,403,821 bp from pter |
Size:
|
6,746 bases |
Orientation:
|
minus strand |
1 alternative location:
| ChrX+ 52,128,793-52,135,535 |
RefSeq DNA sequence:- NC_000023.9 NT_011638.12
| Proteins
for XAGE2
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: GAGD3_HUMAN, Q96GT9 (See
protein sequence)Recommended Name: G antigen family D member 3 Size: 111 amino acids; 12354 Da
Secondary accessions: Q5HYR4REFSEQ proteins: NP_570133.1
ENSEMBL proteins: ENSP00000286049
Human Recombinant Proteins  Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
Antibodies for XAGE2:
Assays for XAGE2: | Protein
Domains/
Families
for XAGE2(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q96GT9
ProtoNet protein and cluster: Q96GT9 1 Blocks protein family: IPB008625 GAGE
UniProtKB/Swiss-Prot: GAGD3_HUMAN, Q96GT9Similarity: Belongs to the GAGE family | Gene Function
for XAGE2
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_130777
 Applied Biosystems Silencer® siRNAs for XAGE2
 Sigma-Aldrich siRNA for XAGE2
Sigma-Aldrich shRNA for XAGE2
Explore Sigma-Aldrich super-pooled esiRNAs
OriGene GFP tagged cDNA clone in CMV expression vector: NM_130777
Myc/DDK tagged cDNA clone in CMV expression vector: NM_130777
untagged cDNA clone in CMV expression vector: NM_130777
Primers:  Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
OriGene genome-wide validated SYBR primer pairs: NM_130777
UniProtKB/Swiss-Prot: GAGD3_HUMAN, Q96GT9Function: Unknown | Pathways & Interactions
for XAGE2
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
2 Interacting proteins for XAGE2 (Q96GT92) via UniProtKB, MINT, and/or STRINGAbout this table
|
Drugs & Compounds
for XAGE2(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for XAGE2
|
Transcripts
for XAGE2(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene,
Expression Assays from Applied Biosystems)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_130777
Sigma-Aldrich siRNA for XAGE2
Sigma-Aldrich shRNA for XAGE2
Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer® siRNAs: NM_130777 REFSEQ mRNAs for XAGE2 gene: NM_130777.1
Applied Biosystems TaqMan ® Gene Expression Assays: NM_130777
OriGene GFP tagged cDNA clone in CMV expression vector: NM_130777
Myc/DDK tagged cDNA clone in CMV expression vector: NM_130777
untagged cDNA clone in CMV expression vector: NM_130777
Additional cDNA sequence: AJ318880.1 BC009232.2 BC066311.1 2 DOTS entries: DT.214881 DT.95070869 24/50 AceView cDNA sequences (see all 50
):BC066311 NM_130777 W93043 BX103525 AI189715 AJ318880 N30289 AA505794 AI186558 AI128458 AI149003 H00523 AA722699 BE734431 T87105 BG336384 BG623213 AA993199 AA039331 BE281431 H00469 BC009232 BE903565 AI740470
 highest scoring ESTs for XAGE2:AA039250 AJ318880 BC009232 BC066311 BE281431 BE733225 BE734431 BE900651 BE903565 BG336384 Unigene Cluster for XAGE2: X antigen family, member 2 Hs.522654 [show with all ESTs]Unigene Representative Sequence: BE900651
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation: ENST00000286049
|
Expression
for XAGE2
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| XAGE2 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for XAGE2
1 / 2 / 3 3 probe-sets matching XAGE2 gene Data from
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.522654
|
Orthologs
for XAGE2
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
| ENSEMBL Gene Tree for XAGE2 | Paralogs
for XAGE2(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for XAGE2 gene
- CTD-2267G17.31 XAGE32 GAGE2D2 GAGE102 GAGE12H2 ENSG000001691642 XAGE52 XAGE2B2
- GAGE12C2 GAGE12E2 GAGE2E2 GAGE12 GAGE2C2 GAGE12F2 GAGE132 PAGE12
- GAGE12G2 GAGE2B2 GAGE2A2 GAGE12J2
|
SNPs/Variants
for XAGE2(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
| -- |
Disorders & Mutations
for XAGE2
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 300416
|
Medical News
for XAGE2(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for XAGE2 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 7 PubMed articles for XAGE2 gene: |
Search for XAGE2
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing XAGE2
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing XAGE2
(According to HUGE)
About This Section
| -- |
Specialized Databases showing XAGE2(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| About This Section
| --
| Services
for XAGE2(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section
| 
Products for XAGE2:
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