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Aliases & Descriptions for XAGE1E
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section
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Aliases CT12.1 3 GAGED2 3 XAGE1A 3
Descriptions Cancer/testis antigen 12.1 3 Protein XAGE-1 3 X antigen family member 1E 2 X antigen family, member 1E 2 xage-1 p16 2
Search outside databases for aliases for XAGE1E genePrevious GC identifers: GC0XU900700 GC0XM052559 GC0XM052273
Summaries for XAGE1E (According to Entrez Gene ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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EntrezGene summary for XAGE1E : XAGE1E is 1 of 5 copies of the XAGE1 gene (see XAGE1D; MIM 300289) (Chen et al., 2006 [PubMed16382448]).[supplied by OMIM] UniProtKB/Swiss-Prot: GAGD2_HUMAN, Q9HD64 Function : Unknown
Genomic Location for XAGE1E
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 36) ,
and/or miRBase ,
Genomic Views according to
UCSC and
Ensembl ,
Transcription factor binding sites according to
SABiosciences )About This Section
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Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: Xp11.22 Ensembl cytogenetic band: Xp11.22 HGNC cytogenetic band: Xp11.22 XAGE1E Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome X GeneLoc Exon Structure
GeneLoc location for GC0XP052257:
(about GC identifiers )
Start:
52,255,543 bp from pter
End:
52,260,679 bp from pter
Size:
5,137 bases
Orientation:
plus strand
1 alternative location : Chr X- 52,557,778-52,562,914
Proteins for XAGE1E
(According to
1 UniProtKB ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Enzo Life Sciences ,
Abnova ,
OriGene and/or,
Abcam ,
Biochemical Assays by
Invitrogen ,
Millipore ,
R&D Systems ,
Cell Signaling Technology , and/or
Enzo Life Sciences ,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene ,
Antibodies by Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Cell Signaling Technology ,
Abcam ,
Abnova , and/or
Novus Biologicals )
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UniProtKB/Swiss-Prot: GAGD2_HUMAN, Q9HD64 (See
protein sequence )Recommended Name: G antigen family D member 2 Size : 160 amino acids; 17751 Da
Secondary accessions : A6NJ94 Q5JPP0 Q5JPP3 Q8WWG5 Q8WWG6 Q969J6Alternative splicing : 3 isoforms : Q9HD64-3 Q9HD64-2 Q9HD64-4
REFSEQ proteins (3 alternative transcripts):
NP_001091072.1 NP_001091073.1 NP_001091074.1 ENSEMBL proteins: ENSP00000364720 ENSP00000364717 ENSP00000364713 Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells Antibodies for XAGE1E: Assays for XAGE1E:
Protein
Domains/ Families for XAGE1E(According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Graphical View of Domain Structure for InterPro Entry Q9HD64 ProtoNet protein and cluster: Q9HD64
1 Blocks protein family : IPB008625 GAGE UniProtKB/Swiss-Prot: GAGD2_HUMAN, Q9HD64 Similarity : Belongs to the GAGE family
Gene Function for XAGE1E
(According to MGI Jun 06 2009, UniProtKB ,
IUBMB ,and/or Genatlas ,
shRNA from
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Sigma-Aldrich , RNAi from
Sigma-Aldrich ,
RNAi Products ,
Clones , and
Q-PCR Products
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OriGene , and/or
Abnova ,
siRNAs from
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SYBR primers from OriGene ,
Cell-based Assays from Millipore ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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                 Browse Origene for 29mer shRNA kit in GFP-retroviral vector Applied Biosystems Silencer ® siRNAs for XAGE1E Browse siRNA at Sigma-Aldrich Browse shRNA at Sigma-Aldrich Explore Sigma-Aldrich super-pooled esiRNAs                OriGene GFP tagged cDNA clones in CMV expression vector (see all 3 ): NM_001097603                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 3 ): NM_001097603                                  untagged cDNA clones in CMV expression vector (see all 3 ): NM_001097603  Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_001097603 UniProtKB/Swiss-Prot: GAGD2_HUMAN, Q9HD64 Function : Unknown
Pathways & Interactions for XAGE1E
(Pathways according to Invitrogen
(maps by GeneGo ),
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Proteins Network according to
SABiosciences ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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Drugs & Compounds for XAGE1E (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
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Browse Tocris compounds for XAGE1E
Transcripts for XAGE1E(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
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                 Browse Origene for 29mer shRNA kit in GFP-retroviral vector Browse siRNA at Sigma-Aldrich Browse shRNA at Sigma-Aldrich Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer ® siRNAs: NM_001097603 NM_001097604 NM_001097605
REFSEQ mRNAs for XAGE1E gene (3 alternative transcripts): NM_001097603.1 NM_001097604.1 NM_001097605.1
Applied Biosystems TaqMan ® Gene Expression Assays: NM_001097603 NM_001097604 NM_001097605
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 3 ): NM_001097603                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 3 ): NM_001097603                                  untagged cDNA clones in CMV expression vector (see all 3 ): NM_001097603   GeneLoc Exon Structure 3 Ensembl transcripts including schematic representations : ENST00000375570
ENST00000375567
ENST00000375563
Expression for XAGE1E
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Expression Assays from
Applied Biosystems
)
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XAGE1E expression in normal and diseased human tissues Applied Biosystems TaqMan ® Gene Expression Assays for XAGE1E 1 / 2
3 probe-sets matching XAGE1E gene Data from
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: --UniProtKB/Swiss-Prot: GAGD2_HUMAN, Q9HD64 Tissue specificity : In normal tissues, highly expressed in testis. Expressed also in many differenttypes of cancers: highly expressed in breast cancer, prostate cancer and many types of lungcancers, including squamous cell carcinoma, small cell carcinoma, non-small cell carcinoma, andadenocarcinoma, as well as in Ewing's cell lines, in some Ewing's sarcoma patient samples, and inone of one alveolar rhabdomyosarcoma patient sample
Orthologs for XAGE1E
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
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Orthologs for XAGE1E gene from 1 species
Organism
Gene
Locus
Description
Human Similarity
NCBI accessions
chimpanzee (Pan troglodytes)
XAGE1A1
--
X antigen family, member 1A
98.75(n) 96.87(a)
741118 XM_001143525.1 XP_001143525.1
About this table Species with no ortholog for XAGE1E ENSEMBL Gene Tree for XAGE1E Paralogs for XAGE1E (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section
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Paralogs for XAGE1E gene XAGE1D 1 2 XAGE1B 2 XAGE1A 2 XAGE1C 2
SNPs/Variants for XAGE1E (According to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Genotyping Reagents from
Applied Biosystems )
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Disorders & Mutations for XAGE1E
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
HGMD, GAD ,
HuGE Navigator ,
BCGD ,
and/or TGDB .)
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OMIM: 300745
Medical News for XAGE1E (Possibly Related Articles in
Doctor's Guide )
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Publications for XAGE1E (in
PubMed .
Associations of this gene to articles via
1 Novoseek ,
2 HGNC ,
3 Entrez Gene ,
4 UniProtKB/Swiss-Prot ,
5 UniProtKB/TrEMBL ,
6 GAD , and/or
7 PharmGKB )
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6 PubMed articles for XAGE1E gene :
Search for XAGE1E
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing XAGE1E
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
and/or
H-InvDB )
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Other Databases showing XAGE1E
(According to HUGE )
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Specialized Databases showing XAGE1E (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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