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Aliases for XAGE1E Gene

Aliases for XAGE1E Gene

  • X Antigen Family Member 1E 2
  • XAGE1A XAGE1B XAGE1C XAGE1D XAGE1E 4
  • G Antigen Family D Member 2 4
  • X Antigen Family, Member 1E 2
  • Cancer/Testis Antigen 12.1 4
  • GAGED2 4
  • CT12.1 4
  • XAGE-1 4
  • XAGE1 4

External Ids for XAGE1E Gene

Previous GeneCards Identifiers for XAGE1E Gene

  • GC0XU900700
  • GC0XM052559
  • GC0XM052273
  • GC0XP052257
  • GC0XP052259
  • GC0XM052512

Summaries for XAGE1E Gene

GeneCards Summary for XAGE1E Gene

XAGE1E (X Antigen Family Member 1E) is a Protein Coding gene.

Additional gene information for XAGE1E Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for XAGE1E Gene

Genomics for XAGE1E Gene

GeneHancer (GH) Regulatory Elements for XAGE1E Gene


Top Transcription factor binding sites by QIAGEN in the XAGE1E gene promoter:

Genomic Locations for XAGE1E Gene

No location information available

Genomic View for XAGE1E Gene


Cytogenetic band:

No data available for RefSeq DNA sequence for XAGE1E Gene

Proteins for XAGE1E Gene

  • Protein details for XAGE1E Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9HD64-XAGE1_HUMAN
    Recommended name:
    X antigen family member 1
    Protein Accession:
    Q9HD64
    Secondary Accessions:
    • A6NJ94
    • Q5JPN8
    • Q5JPP0
    • Q5JPP3
    • Q8WWG5
    • Q8WWG6
    • Q969J6

    Protein attributes for XAGE1E Gene

    Size:
    81 amino acids
    Molecular mass:
    9078 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • According to PubMed:11992404, the transcription of XAGE1A is regulated by methylation of the CpG island in the promoter, and four alternative RNA splicing variants, XAGE-1a, b, c have been identified.
    SequenceCaution:
    • Sequence=AAG01401.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=AAH09538.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=CAC82986.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=CAI40888.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI40895.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI41526.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI41531.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI41534.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for XAGE1E Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for XAGE1E Gene

Post-translational modifications for XAGE1E Gene

No data available for DME Specific Peptides for XAGE1E Gene

Domains & Families for XAGE1E Gene

Protein Domains for XAGE1E Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for XAGE1E Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9HD64

UniProtKB/Swiss-Prot:

XAGE1_HUMAN :
  • Belongs to the GAGE family.
Family:
  • Belongs to the GAGE family.
genes like me logo Genes that share domains with XAGE1E: view

No data available for Gene Families for XAGE1E Gene

Function for XAGE1E Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for XAGE1E Gene

Localization for XAGE1E Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for XAGE1E Gene

Pathways & Interactions for XAGE1E Gene

SuperPathways for XAGE1E Gene

No Data Available

Gene Ontology (GO) - Biological Process for XAGE1E Gene

None

No data available for Pathways by source and SIGNOR curated interactions for XAGE1E Gene

Drugs & Compounds for XAGE1E Gene

No Compound Related Data Available

Transcripts for XAGE1E Gene

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for XAGE1E Gene

No ASD Table

Relevant External Links for XAGE1E Gene

ECgene alternative splicing isoforms for
XAGE1E

No data available for mRNA/cDNA for XAGE1E Gene

Expression for XAGE1E Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for XAGE1E Gene

mRNA differential expression in normal tissues according to GTEx for XAGE1E Gene

This gene is overexpressed in Testis (x53.0).

Protein differential expression in normal tissues from HIPED for XAGE1E Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (32.2), Colon muscle (27.6), and Testis (6.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for XAGE1E Gene



Protein tissue co-expression partners for XAGE1E Gene

NURSA nuclear receptor signaling pathways regulating expression of XAGE1E Gene:

XAGE1E

mRNA Expression by UniProt/SwissProt for XAGE1E Gene:

Q9HD64-XAGE1_HUMAN
Tissue specificity: In normal tissues, highly expressed in testis. Expressed also in many different types of cancers: highly expressed in breast cancer, prostate cancer and many types of lung cancers, including squamous cell carcinoma, small cell carcinoma, non-small cell carcinoma, and adenocarcinoma, as well as in Ewings cell lines, in some Ewings sarcoma patient samples, and in one of one alveolar rhabdomyosarcoma patient sample.
genes like me logo Genes that share expression patterns with XAGE1E: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for XAGE1E Gene

Orthologs for XAGE1E Gene

No data available for Orthologs and Evolution for XAGE1E Gene

Paralogs for XAGE1E Gene

(1) SIMAP similar genes for XAGE1E Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with XAGE1E: view

No data available for Paralogs for XAGE1E Gene

Variants for XAGE1E Gene

Structural Variations from Database of Genomic Variants (DGV) for XAGE1E Gene

Variant ID Type Subtype PubMed ID
esv1003754 CNV loss 20482838
esv991419 CNV loss 20482838
esv994563 CNV loss 20482838

Additional Variant Information for XAGE1E Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
XAGE1E

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for XAGE1E Gene

Disorders for XAGE1E Gene

Additional Disease Information for XAGE1E

No disorders were found for XAGE1E Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for XAGE1E Gene

Publications for XAGE1E Gene

  1. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 58
  2. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H … Mohammed S (Journal of proteome research 2013) 4 58
  3. Identification of XAGE-1 isoforms: predominant expression of XAGE-1b in testis and tumors. (PMID: 17335148) Sato S … Nakayama E (Cancer immunity 2007) 4 58
  4. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross MT … Bentley DR (Nature 2005) 4 58
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58

Products for XAGE1E Gene

Sources for XAGE1E Gene

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