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Aliases for XAGE1D Gene

Aliases for XAGE1D Gene

  • X Antigen Family Member 1D 2
  • Cancer/Testis Antigen Family 12, Member 1d 2
  • XAGE1A XAGE1B XAGE1C XAGE1D XAGE1E 4
  • G Antigen Family D Member 2 4
  • X Antigen Family, Member 1D 2
  • Cancer/Testis Antigen 12.1 4
  • GAGED2 4
  • CT12.1 4
  • XAGE-1 4
  • XAGE1 4

External Ids for XAGE1D Gene

Previous GeneCards Identifiers for XAGE1D Gene

  • GC0XU900701
  • GC0XM052545

Summaries for XAGE1D Gene

GeneCards Summary for XAGE1D Gene

XAGE1D (X Antigen Family Member 1D) is a Protein Coding gene.

Gene Wiki entry for XAGE1D Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for XAGE1D Gene

Genomics for XAGE1D Gene

Genomic Location for XAGE1D Gene

No location information available

Genomic View for XAGE1D Gene


Cytogenetic band:

No data available for Regulatory Elements and RefSeq DNA sequence for XAGE1D Gene

Proteins for XAGE1D Gene

  • Protein details for XAGE1D Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9HD64-XAGE1_HUMAN
    Recommended name:
    X antigen family member 1
    Protein Accession:
    Q9HD64
    Secondary Accessions:
    • A6NJ94
    • Q5JPN8
    • Q5JPP0
    • Q5JPP3
    • Q8WWG5
    • Q8WWG6
    • Q969J6

    Protein attributes for XAGE1D Gene

    Size:
    81 amino acids
    Molecular mass:
    9078 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • According to PubMed:11992404, the transcription of XAGE1A is regulated by methylation of the CpG island in the promoter, and four alternative RNA splicing variants, XAGE-1a, b, c have been identified.
    SequenceCaution:
    • Sequence=AAG01401.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=AAH09538.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=CAC82986.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=CAI40888.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI40895.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI41526.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI41531.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI41534.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for XAGE1D Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for XAGE1D Gene

Post-translational modifications for XAGE1D Gene

  • Ubiquitination at Lys12
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for XAGE1D Gene

Domains & Families for XAGE1D Gene

Protein Domains for XAGE1D Gene

InterPro:
Blocks:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q9HD64

UniProtKB/Swiss-Prot:

XAGE1_HUMAN :
  • Belongs to the GAGE family.
Family:
  • Belongs to the GAGE family.
genes like me logo Genes that share domains with XAGE1D: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for XAGE1D Gene

Function for XAGE1D Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for XAGE1D Gene

Localization for XAGE1D Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for XAGE1D Gene

Pathways & Interactions for XAGE1D Gene

SuperPathways for XAGE1D Gene

No Data Available

Gene Ontology (GO) - Biological Process for XAGE1D Gene

None

No data available for Pathways by source and SIGNOR curated interactions for XAGE1D Gene

Transcripts for XAGE1D Gene

Alternative Splicing Database (ASD) splice patterns (SP) for XAGE1D Gene

No ASD Table

Relevant External Links for XAGE1D Gene

ECgene alternative splicing isoforms for
XAGE1D

Expression for XAGE1D Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for XAGE1D Gene

Protein differential expression in normal tissues from HIPED for XAGE1D Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (32.2), Colon muscle (27.6), and Testis (6.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for XAGE1D Gene



Protein tissue co-expression partners for XAGE1D Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of XAGE1D Gene:

XAGE1D

mRNA Expression by UniProt/SwissProt for XAGE1D Gene:

Q9HD64-XAGE1_HUMAN
Tissue specificity: In normal tissues, highly expressed in testis. Expressed also in many different types of cancers: highly expressed in breast cancer, prostate cancer and many types of lung cancers, including squamous cell carcinoma, small cell carcinoma, non-small cell carcinoma, and adenocarcinoma, as well as in Ewings cell lines, in some Ewings sarcoma patient samples, and in one of one alveolar rhabdomyosarcoma patient sample.
genes like me logo Genes that share expression patterns with XAGE1D: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for XAGE1D Gene

Orthologs for XAGE1D Gene

No data available for Orthologs and Evolution for XAGE1D Gene

Paralogs for XAGE1D Gene

(1) SIMAP similar genes for XAGE1D Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with XAGE1D: view

No data available for Paralogs for XAGE1D Gene

Variants for XAGE1D Gene

Relevant External Links for XAGE1D Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
XAGE1D

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for XAGE1D Gene

Disorders for XAGE1D Gene

No disorders were found for XAGE1D Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for XAGE1D Gene

Publications for XAGE1D Gene

  1. Identification of XAGE-1 isoforms: predominant expression of XAGE-1b in testis and tumors. (PMID: 17335148) Sato S. … Nakayama E. (Cancer Immun. 2007) 4 22 64
  2. Characterization of overlapping XAGE-1 transcripts encoding a cancer testis antigen expressed in lung, breast, and other types of cancers. (PMID: 12479262) Egland K.A. … Pastan I. (Mol. Cancer Ther. 2002) 4 22 64
  3. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 64
  4. mRNA expression of the XAGE-1 gene in human acute leukemia. (PMID: 20178013) Ji Y. … Gu L. (Int. J. Hematol. 2010) 22 64
  5. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 4 64

Products for XAGE1D Gene

Sources for XAGE1D Gene

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