Free for academic non-profit institutions. Other users need a Commercial license

Aliases for XAGE1C Gene

Aliases for XAGE1C Gene

  • X Antigen Family Member 1C 2
  • Cancer/Testis Antigen Family 12, Member 1c 2
  • XAGE1A XAGE1B XAGE1C XAGE1D XAGE1E 4
  • G Antigen Family D Member 2 4
  • X Antigen Family, Member 1C 2
  • Cancer/Testis Antigen 12.1 4
  • GAGED2 4
  • CT12.1 4
  • XAGE-1 4
  • XAGE1 4

External Ids for XAGE1C Gene

Previous GeneCards Identifiers for XAGE1C Gene

  • GC0XU900703
  • GC0XP052529
  • GC0XP052511

Summaries for XAGE1C Gene

GeneCards Summary for XAGE1C Gene

XAGE1C (X Antigen Family Member 1C) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for XAGE1C Gene

Genomics for XAGE1C Gene

Regulatory Elements for XAGE1C Gene


Genomic Location for XAGE1C Gene

No location information available

Genomic View for XAGE1C Gene


Cytogenetic band:

No data available for RefSeq DNA sequence for XAGE1C Gene

Proteins for XAGE1C Gene

  • Protein details for XAGE1C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9HD64-XAGE1_HUMAN
    Recommended name:
    X antigen family member 1
    Protein Accession:
    Q9HD64
    Secondary Accessions:
    • A6NJ94
    • Q5JPN8
    • Q5JPP0
    • Q5JPP3
    • Q8WWG5
    • Q8WWG6
    • Q969J6

    Protein attributes for XAGE1C Gene

    Size:
    81 amino acids
    Molecular mass:
    9078 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • According to PubMed:11992404, the transcription of XAGE1A is regulated by methylation of the CpG island in the promoter, and four alternative RNA splicing variants, XAGE-1a, b, c have been identified.
    SequenceCaution:
    • Sequence=AAG01401.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=AAH09538.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=CAC82986.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=CAI40888.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI40895.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI41526.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI41531.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI41534.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for XAGE1C Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for XAGE1C Gene

Post-translational modifications for XAGE1C Gene

  • Ubiquitination at Lys 12
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for XAGE1C Gene

Domains & Families for XAGE1C Gene

Protein Domains for XAGE1C Gene

InterPro:
Blocks:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q9HD64

UniProtKB/Swiss-Prot:

XAGE1_HUMAN :
  • Belongs to the GAGE family.
Family:
  • Belongs to the GAGE family.
genes like me logo Genes that share domains with XAGE1C: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for XAGE1C Gene

Function for XAGE1C Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for XAGE1C Gene

Localization for XAGE1C Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for XAGE1C Gene

Pathways & Interactions for XAGE1C Gene

SuperPathways for XAGE1C Gene

No Data Available

Gene Ontology (GO) - Biological Process for XAGE1C Gene

None

No data available for Pathways by source and SIGNOR curated interactions for XAGE1C Gene

Drugs & Compounds for XAGE1C Gene

No Compound Related Data Available

Transcripts for XAGE1C Gene

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for XAGE1C Gene

No ASD Table

Relevant External Links for XAGE1C Gene

ECgene alternative splicing isoforms for
XAGE1C

No data available for mRNA/cDNA for XAGE1C Gene

Expression for XAGE1C Gene

mRNA expression in normal human tissues for XAGE1C Gene

Protein differential expression in normal tissues from HIPED for XAGE1C Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (32.2), Colon muscle (27.6), and Testis (6.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for XAGE1C Gene



Protein tissue co-expression partners for XAGE1C Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of XAGE1C Gene:

XAGE1C

mRNA Expression by UniProt/SwissProt for XAGE1C Gene:

Q9HD64-XAGE1_HUMAN
Tissue specificity: In normal tissues, highly expressed in testis. Expressed also in many different types of cancers: highly expressed in breast cancer, prostate cancer and many types of lung cancers, including squamous cell carcinoma, small cell carcinoma, non-small cell carcinoma, and adenocarcinoma, as well as in Ewings cell lines, in some Ewings sarcoma patient samples, and in one of one alveolar rhabdomyosarcoma patient sample.
genes like me logo Genes that share expression patterns with XAGE1C: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for XAGE1C Gene

Orthologs for XAGE1C Gene

No data available for Orthologs and Evolution for XAGE1C Gene

Paralogs for XAGE1C Gene

(1) SIMAP similar genes for XAGE1C Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with XAGE1C: view

No data available for Paralogs for XAGE1C Gene

Variants for XAGE1C Gene

Relevant External Links for XAGE1C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
XAGE1C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for XAGE1C Gene

Disorders for XAGE1C Gene

No disorders were found for XAGE1C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for XAGE1C Gene

Publications for XAGE1C Gene

  1. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 65
  2. Identification of XAGE-1 isoforms: predominant expression of XAGE-1b in testis and tumors. (PMID: 17335148) Sato S. … Nakayama E. (Cancer Immun. 2007) 4 65
  3. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 4 65
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 65
  5. The XAGE family of cancer/testis-associated genes: alignment and expression profile in normal tissues, melanoma lesions and Ewing's sarcoma. (PMID: 11992404) Zendman A.J.W. … van Muijen G.N.P. (Int. J. Cancer 2002) 4 65

Products for XAGE1C Gene

Sources for XAGE1C Gene

Content
Loading form....