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Aliases for WTAPP1 Gene

Aliases for WTAPP1 Gene

  • Wilms Tumor 1 Associated Protein Pseudogene 1 2 3 5

External Ids for WTAPP1 Gene

Previous GeneCards Identifiers for WTAPP1 Gene

  • GC11P102618

Summaries for WTAPP1 Gene

GeneCards Summary for WTAPP1 Gene

WTAPP1 (Wilms Tumor 1 Associated Protein Pseudogene 1) is a Pseudogene. Diseases associated with WTAPP1 include Wilms Tumor 1.

Additional gene information for WTAPP1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WTAPP1 Gene

Genomics for WTAPP1 Gene

GeneHancer (GH) Regulatory Elements for WTAPP1 Gene

Promoters and enhancers for WTAPP1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11I102759 Enhancer 1.2 FANTOM5 Ensembl ENCODE 0.4 +15.0 15025 4.1 HDAC1 NFIB PLRG1 RFX5 ZNF366 ZNF350 RCOR1 ATF7 FOS CEBPB DYNC2H1 C11orf70 MMP1 MMP8 MMP3 MMP27 MMP7 BIRC2 ENSG00000225678 LOC100421658
GH11I102780 Promoter/Enhancer 1.3 EPDnew Ensembl ENCODE 0.3 +33.8 33846 1 CTCF JUND FOXA2 JUN SMC3 FOSL2 RAD21 TRIM28 MMP10 MMP3 MMP1 WTAPP1
GH11I102727 Enhancer 0.9 FANTOM5 Ensembl ENCODE 0.4 -18.8 -18842 1.5 JUND JUN FOS MMP8 MMP27 MMP10 MMP1 MMP3 RNU7-159P BIRC2 TMEM123 BIRC3 WTAPP1
GH11I102757 Enhancer 0.8 Ensembl ENCODE 0.4 +11.5 11484 0.9 JUN CEBPB CEBPG EP300 ATF2 RFX5 ZNF629 IKZF1 FOS ATF7 MMP27 ENSG00000225678 LOC100421658 WTAPP1
GH11I102733 Enhancer 0.7 ENCODE 0.4 -13.5 -13523 0.2 MEIS2 CTCF PKNOX1 RAD21 ARID2 SCRT2 SMC3 ZNF143 RUNX3 SCRT1 MMP10 MMP27 MMP1 MMP3 RNU7-159P MMP8 WTAPP1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around WTAPP1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for WTAPP1 Gene

Genomic Locations for WTAPP1 Gene
chr11:102,746,968-102,836,766
(GRCh38/hg38)
Size:
89,799 bases
Orientation:
Plus strand
chr11:102,617,699-102,707,497
(GRCh37/hg19)

Genomic View for WTAPP1 Gene

Genes around WTAPP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
WTAPP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for WTAPP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WTAPP1 Gene

Proteins for WTAPP1 Gene

Post-translational modifications for WTAPP1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for WTAPP1 Gene

Domains & Families for WTAPP1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for WTAPP1 Gene

Function for WTAPP1 Gene

Phenotypes From GWAS Catalog for WTAPP1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for WTAPP1 Gene

Localization for WTAPP1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for WTAPP1 Gene

Pathways & Interactions for WTAPP1 Gene

SuperPathways for WTAPP1 Gene

No Data Available

Interacting Proteins for WTAPP1 Gene

Gene Ontology (GO) - Biological Process for WTAPP1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for WTAPP1 Gene

Drugs & Compounds for WTAPP1 Gene

No Compound Related Data Available

Transcripts for WTAPP1 Gene

mRNA/cDNA for WTAPP1 Gene

(2) Additional mRNA sequences :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for WTAPP1 Gene

Wilms tumor 1 associated protein pseudogene 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for WTAPP1 Gene

No ASD Table

Relevant External Links for WTAPP1 Gene

GeneLoc Exon Structure for
WTAPP1
ECgene alternative splicing isoforms for
WTAPP1

Expression for WTAPP1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for WTAPP1 Gene

mRNA differential expression in normal tissues according to GTEx for WTAPP1 Gene

This gene is overexpressed in Minor Salivary Gland (x14.0) and Testis (x5.7).

NURSA nuclear receptor signaling pathways regulating expression of WTAPP1 Gene:

WTAPP1

SOURCE GeneReport for Unigene cluster for WTAPP1 Gene:

Hs.661772
genes like me logo Genes that share expression patterns with WTAPP1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for WTAPP1 Gene

Orthologs for WTAPP1 Gene

Evolution for WTAPP1 Gene

ENSEMBL:
Gene Tree for WTAPP1 (if available)
TreeFam:
Gene Tree for WTAPP1 (if available)

No data available for Orthologs for WTAPP1 Gene

Paralogs for WTAPP1 Gene

No data available for Paralogs for WTAPP1 Gene

Variants for WTAPP1 Gene

Sequence variations from dbSNP and Humsavar for WTAPP1 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs10488 benign, not specified 102,797,291(+) C/G/T intron_variant
rs1051121 benign, not specified 102,795,242(+) C/T intron_variant
rs1144391 benign, not specified 102,792,751(+) A/T intron_variant
rs17884110 benign, not specified 102,792,746(+) G/GG intron_variant
rs470558 benign, not specified 102,795,585(+) T/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for WTAPP1 Gene

Variant ID Type Subtype PubMed ID
esv1010986 CNV deletion 20482838
esv1277207 CNV deletion 17803354
esv2745001 CNV deletion 23290073
esv2745002 CNV deletion 23290073

Additional Variant Information for WTAPP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
WTAPP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for WTAPP1 Gene

Disorders for WTAPP1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for WTAPP1 Gene - From: GeneCards

Disorder Aliases PubMed IDs
wilms tumor 1
  • wt1
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for WTAPP1

genes like me logo Genes that share disorders with WTAPP1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for WTAPP1 Gene

Publications for WTAPP1 Gene

  1. Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation. (PMID: 25340798) Kauwe JS … Goate AM (PLoS genetics 2014) 3 58
  2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 58
  3. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PMID: 19913121) Talmud PJ … BRIGHT Consortium (American journal of human genetics 2009) 3 58
  4. Genome-wide association scan identifies variants near Matrix Metalloproteinase (MMP) genes on chromosome 11q21-22 strongly associated with serum MMP-1 levels. (PMID: 20031604) Cheng YC … Pollin TI (Circulation. Cardiovascular genetics 2009) 3 58
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58

Products for WTAPP1 Gene

Sources for WTAPP1 Gene

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