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Aliases for WT1-AS Gene

Subcategory (RNA class) for WT1-AS Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for WT1-AS Gene

  • WT1 Antisense RNA 2 3 5
  • WT1 Antisense RNA (Non-Protein Coding) 2 3
  • Wilms Tumor Upstream Neighbor 1 2 3
  • Wilms Tumor Associated Protein 2 3
  • WIT-1 3 4
  • WIT1 3 4
  • Wilms Tumor-Associated Antisense RNA 4
  • WT1-AS1 3
  • WT1AS 3

External Ids for WT1-AS Gene

Previous HGNC Symbols for WT1-AS Gene

  • WIT1

Previous GeneCards Identifiers for WT1-AS Gene

  • GC11P032459
  • GC11P032438
  • GC11P032445
  • GC11P032449
  • GC11P032454
  • GC11P032461

Summaries for WT1-AS Gene

Entrez Gene Summary for WT1-AS Gene

  • This gene is located upstream of the Wilms tumor 1 (WT1) gene; these two genes are bi-directionally transcribed from the same promoter region. This gene is imprinted in kidney, with preferential expression from the paternal allele. Imprinting defects at chromosome 11p13 may contribute to tumorigenesis. [provided by RefSeq, May 2014]

GeneCards Summary for WT1-AS Gene

WT1-AS (WT1 Antisense RNA) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with WT1-AS include Ovarian Clear Cell Adenocarcinoma.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WT1-AS Gene

Genomics for WT1-AS Gene

Regulatory Elements for WT1-AS Gene

Enhancers for WT1-AS Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G032374 1.1 ENCODE dbSUPER 11.7 -61.1 -61119 0.1 ELF3 CTCF ATF1 CBX3 RB1 TBL1XR1 MAX RAD21 E2F1 CBX5 WT1-AS WT1 EIF3M THEM7P
GH11G032333 0.9 Ensembl ENCODE 11 -101.8 -101811 1.1 CTCF MAX NR3C1 RAD21 POLR2A HDAC2 ZNF24 HNF4A WT1-AS WT1 CCDC73 THEM7P PIR50067
GH11G032405 0.8 dbSUPER 12 -29.5 -29499 1.0 HDAC1 ATF1 RB1 AGO1 ETV6 CREM NCOA1 ZNF592 NFIC IKZF1 WT1 WT1-AS CCDC73 THEM7P
GH11G032404 0.8 dbSUPER 11.5 -30.7 -30723 1.3 HDAC1 CTCF ATF1 RB1 SUZ12 AGO1 JUN NCOR1 CREM EZH2 WT1 WT1-AS CSTF3 THEM7P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around WT1-AS on UCSC Golden Path with GeneCards custom track

Genomic Location for WT1-AS Gene

32,435,518 bp from pter
32,458,769 bp from pter
23,252 bases
Plus strand

Genomic View for WT1-AS Gene

Genes around WT1-AS on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
WT1-AS Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for WT1-AS Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WT1-AS Gene

Proteins for WT1-AS Gene

  • Protein details for WT1-AS Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative Wilms tumor upstream neighbor 1 gene protein
    Protein Accession:
    Secondary Accessions:
    • Q4KMY0
    • Q96A27

    Protein attributes for WT1-AS Gene

    92 amino acids
    Molecular mass:
    10039 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAA49572.1; Type=Frameshift; Positions=83; Evidence={ECO:0000305};

neXtProt entry for WT1-AS Gene

Post-translational modifications for WT1-AS Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for WT1-AS Gene

Domains & Families for WT1-AS Gene

Gene Families for WT1-AS Gene

Protein Domains for WT1-AS Gene


Suggested Antigen Peptide Sequences for WT1-AS Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with WT1-AS: view

No data available for UniProtKB/Swiss-Prot for WT1-AS Gene

Function for WT1-AS Gene

Gene Ontology (GO) - Molecular Function for WT1-AS Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with WT1-AS: view
genes like me logo Genes that share phenotypes with WT1-AS: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for WT1-AS Gene

Localization for WT1-AS Gene

Gene Ontology (GO) - Cellular Components for WT1-AS Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with WT1-AS: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for WT1-AS Gene

Pathways & Interactions for WT1-AS Gene

SuperPathways for WT1-AS Gene

No Data Available

Gene Ontology (GO) - Biological Process for WT1-AS Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with WT1-AS: view

No data available for Pathways by source and SIGNOR curated interactions for WT1-AS Gene

Drugs & Compounds for WT1-AS Gene

No Compound Related Data Available

Transcripts for WT1-AS Gene

Unigene Clusters for WT1-AS Gene

WT1 antisense RNA:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for WT1-AS Gene

No ASD Table

Relevant External Links for WT1-AS Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for WT1-AS Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for WT1-AS Gene

mRNA differential expression in normal tissues according to GTEx for WT1-AS Gene

This gene is overexpressed in Ovary (x13.7), Uterus (x8.7), Fallopian Tube (x6.2), and Cervix - Ectocervix (x4.2).

SOURCE GeneReport for Unigene cluster for WT1-AS Gene:

genes like me logo Genes that share expression patterns with WT1-AS: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for WT1-AS Gene

Orthologs for WT1-AS Gene

Evolution for WT1-AS Gene

Gene Tree for WT1-AS (if available)
Gene Tree for WT1-AS (if available)

No data available for Orthologs for WT1-AS Gene

Paralogs for WT1-AS Gene

No data available for Paralogs for WT1-AS Gene

Variants for WT1-AS Gene

Sequence variations from dbSNP and Humsavar for WT1-AS Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs121907911 Pathogenic 32,434,815(-) CGCTA(A/C)GGGCC upstream-variant-2KB, reference, stop-gained
rs776155094 Likely pathogenic 32,435,210(+) CTCGG(-/C)GGCGC upstream-variant-2KB, reference, frameshift-variant
rs2234581 Likely benign 32,435,180(-) AGGGC(A/C/G)GGAGG upstream-variant-2KB, reference, synonymous-codon
rs2234583 Likely benign 32,434,752(-) CCTAA(C/T)GCGCC upstream-variant-2KB, reference, synonymous-codon
rs536728682 Likely benign 32,434,848(+) AACTG(G/T)CCGGA upstream-variant-2KB, reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for WT1-AS Gene

Variant ID Type Subtype PubMed ID
esv3625863 CNV loss 21293372
nsv1044547 CNV gain 25217958
nsv1051559 CNV gain 25217958
nsv832108 CNV loss 17160897
nsv951598 CNV deletion 24416366

Relevant External Links for WT1-AS Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for WT1-AS Gene

Disorders for WT1-AS Gene

MalaCards: The human disease database

(1) MalaCards diseases for WT1-AS Gene - From: GeneCards

Disorder Aliases PubMed IDs
ovarian clear cell adenocarcinoma
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for WT1-AS

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with WT1-AS: view

No data available for UniProtKB/Swiss-Prot and Genatlas for WT1-AS Gene

Publications for WT1-AS Gene

  1. Sequence of the WT1 upstream region including the Wit-1 gene. (PMID: 8406502) Gassler M. … Bruns G.A.P. (Genomics 1993) 2 3 4 64
  2. Tissue, developmental, and tumor-specific expression of divergent transcripts in Wilms tumor. (PMID: 2173145) Huang A. … Williams B.R. (Science 1990) 2 3 4 64
  3. A CTCF-binding silencer regulates the imprinted genes AWT1 and WT1-AS and exhibits sequential epigenetic defects during Wilms' tumourigenesis. (PMID: 17210670) Hancock A.L. … Malik K. (Hum. Mol. Genet. 2007) 2 3 64
  4. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 3 4 64
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64

Products for WT1-AS Gene

Sources for WT1-AS Gene

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