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Aliases for WT1-AS Gene

Subcategory (RNA class) for WT1-AS Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for WT1-AS Gene

  • WT1 Antisense RNA 2 3 5
  • WT1 Antisense RNA (Non-Protein Coding) 2 3
  • Wilms Tumor Upstream Neighbor 1 2 3
  • Wilms Tumor Associated Protein 2 3
  • WIT-1 3 4
  • WIT1 3 4
  • Wilms Tumor-Associated Antisense RNA 4
  • WT1-AS1 3
  • WT1AS 3

External Ids for WT1-AS Gene

Previous HGNC Symbols for WT1-AS Gene

  • WIT1

Previous GeneCards Identifiers for WT1-AS Gene

  • GC11P032459
  • GC11P032438
  • GC11P032445

Summaries for WT1-AS Gene

Entrez Gene Summary for WT1-AS Gene

  • This gene is located upstream of the Wilms tumor 1 (WT1) gene; these two genes are bi-directionally transcribed from the same promoter region. This gene is imprinted in kidney, with preferential expression from the paternal allele. Imprinting defects at chromosome 11p13 may contribute to tumorigenesis. [provided by RefSeq, May 2014]

GeneCards Summary for WT1-AS Gene

WT1-AS (WT1 Antisense RNA) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WT1-AS Gene

Genomics for WT1-AS Gene

Regulatory Elements for WT1-AS Gene

Enhancers for WT1-AS Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around WT1-AS on UCSC Golden Path with GeneCards custom track

Promoters for WT1-AS Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around WT1-AS on UCSC Golden Path with GeneCards custom track

Genomic Location for WT1-AS Gene

32,435,518 bp from pter
32,458,769 bp from pter
23,252 bases
Plus strand

Genomic View for WT1-AS Gene

Genes around WT1-AS on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
WT1-AS Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for WT1-AS Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WT1-AS Gene

Proteins for WT1-AS Gene

  • Protein details for WT1-AS Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative Wilms tumor upstream neighbor 1 gene protein
    Protein Accession:
    Secondary Accessions:
    • Q4KMY0
    • Q96A27

    Protein attributes for WT1-AS Gene

    92 amino acids
    Molecular mass:
    10039 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAA49572.1; Type=Frameshift; Positions=83; Evidence={ECO:0000305};

neXtProt entry for WT1-AS Gene

Proteomics data for WT1-AS Gene at MOPED

Post-translational modifications for WT1-AS Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for WT1-AS Gene

Domains & Families for WT1-AS Gene

Gene Families for WT1-AS Gene

Protein Domains for WT1-AS Gene


Suggested Antigen Peptide Sequences for WT1-AS Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with WT1-AS: view

No data available for UniProtKB/Swiss-Prot for WT1-AS Gene

Function for WT1-AS Gene

Phenotypes for WT1-AS Gene

genes like me logo Genes that share phenotypes with WT1-AS: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for WT1-AS Gene

Localization for WT1-AS Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for WT1-AS Gene

Pathways & Interactions for WT1-AS Gene

SuperPathways for WT1-AS Gene

No Data Available

Gene Ontology (GO) - Biological Process for WT1-AS Gene


No data available for Pathways by source and SIGNOR curated interactions for WT1-AS Gene

Drugs & Compounds for WT1-AS Gene

No Compound Related Data Available

Transcripts for WT1-AS Gene

Unigene Clusters for WT1-AS Gene

WT1 antisense RNA:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for WT1-AS Gene

No ASD Table

Relevant External Links for WT1-AS Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for WT1-AS Gene

mRNA expression in normal human tissues for WT1-AS Gene

mRNA differential expression in normal tissues according to GTEx for WT1-AS Gene

This gene is overexpressed in Ovary (x13.7), Uterus (x8.7), Fallopian Tube (x6.2), and Cervix - Ectocervix (x4.2).

SOURCE GeneReport for Unigene cluster for WT1-AS Gene Hs.567499

genes like me logo Genes that share expression patterns with WT1-AS: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for WT1-AS Gene

Orthologs for WT1-AS Gene

Evolution for WT1-AS Gene

Gene Tree for WT1-AS (if available)
Gene Tree for WT1-AS (if available)

No data available for Orthologs for WT1-AS Gene

Paralogs for WT1-AS Gene

No data available for Paralogs for WT1-AS Gene

Variants for WT1-AS Gene

Sequence variations from dbSNP and Humsavar for WT1-AS Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs6508 - 32,438,918(+) ATGTG(A/G)CGTTG intron-variant, nc-transcript-variant, downstream-variant-500B
rs3087923 - 32,439,078(-) GCAGC(C/G/T)CAGCT intron-variant, nc-transcript-variant, downstream-variant-500B
rs975665 -- 32,441,830(-) ATTTA(G/T)CCAGA intron-variant
rs2073187 -- 32,442,314(-) CTAAG(C/G)TTGAT intron-variant
rs7115617 -- 32,457,329(+) gtggc(A/G)tgatc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for WT1-AS Gene

Variant ID Type Subtype PubMed ID
nsv832108 CNV Loss 17160897

Relevant External Links for WT1-AS Gene

Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for WT1-AS Gene

Disorders for WT1-AS Gene

Relevant External Links for WT1-AS

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for WT1-AS Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for WT1-AS Gene

Publications for WT1-AS Gene

  1. Sequence of the WT1 upstream region including the Wit-1 gene. (PMID: 8406502) Gassler M. … Bruns G.A.P. (Genomics 1993) 2 3 4 67
  2. A CTCF-binding silencer regulates the imprinted genes AWT1 and WT1-AS and exhibits sequential epigenetic defects during Wilms' tumourigenesis. (PMID: 17210670) Hancock A.L. … Malik K. (Hum. Mol. Genet. 2007) 2 3
  3. Restriction landmark genome scanning for aberrant methylation in primary refractory and relapsed acute myeloid leukemia; involvement of the WIT-1 gene. (PMID: 10340388) Plass C. … Caligiuri M.A. (Oncogene 1999) 3 23
  4. Cloning of novel Wilms tumor gene (WT1) cDNAs; evidence for antisense transcription of WT1. (PMID: 8208551) Eccles M.R. … Reeve A.E. (Oncogene 1994) 3 23
  5. Tissue, developmental, and tumor-specific expression of divergent transcripts in Wilms tumor. (PMID: 2173145) Huang A. … Williams B.R. (Science 1990) 2 3

Products for WT1-AS Gene

Sources for WT1-AS Gene