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Aliases for WSCD1 Gene

Aliases for WSCD1 Gene

  • WSC Domain Containing 1 2 3
  • KIAA0523 4

External Ids for WSCD1 Gene

Previous GeneCards Identifiers for WSCD1 Gene

  • GC17P005915
  • GC17P005676

Summaries for WSCD1 Gene

GeneCards Summary for WSCD1 Gene

WSCD1 (WSC Domain Containing 1) is a Protein Coding gene. GO annotations related to this gene include sulfotransferase activity. An important paralog of this gene is WSCD2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WSCD1 Gene

Genomics for WSCD1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for WSCD1 Gene

Start:
5,772,234 bp from pter
End:
6,124,427 bp from pter
Size:
352,194 bases
Orientation:
Plus strand

Genomic View for WSCD1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for WSCD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WSCD1 Gene

Proteins for WSCD1 Gene

  • Protein details for WSCD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q658N2-WSCD1_HUMAN
    Recommended name:
    WSC domain-containing protein 1
    Protein Accession:
    Q658N2
    Secondary Accessions:
    • A8K0N8
    • D3DTM3
    • O60276
    • Q96G45

    Protein attributes for WSCD1 Gene

    Size:
    575 amino acids
    Molecular mass:
    65694 Da
    Quaternary structure:
    No Data Available

neXtProt entry for WSCD1 Gene

Proteomics data for WSCD1 Gene at MOPED

Post-translational modifications for WSCD1 Gene

  • Glycosylation at Asn257 and Asn348
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for WSCD1 Gene

Domains for WSCD1 Gene

Protein Domains for WSCD1 Gene

Suggested Antigen Peptide Sequences for WSCD1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q658N2

UniProtKB/Swiss-Prot:

WSCD1_HUMAN :
  • Q658N2
Domain:
  • Contains 2 WSC domains.
Family:
  • Belongs to the WSCD family.
genes like me logo Genes that share domains with WSCD1: view

No data available for Gene Families for WSCD1 Gene

Function for WSCD1 Gene

Gene Ontology (GO) - Molecular Function for WSCD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008146 sulfotransferase activity IEA --
genes like me logo Genes that share ontologies with WSCD1: view

Animal Model Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for WSCD1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for WSCD1 Gene

Localization for WSCD1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for WSCD1 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for WSCD1 Gene COMPARTMENTS Subcellular localization image for WSCD1 gene
Compartment Confidence
extracellular 2
golgi apparatus 2
cytosol 1
endoplasmic reticulum 1
lysosome 1
nucleus 1

Gene Ontology (GO) - Cellular Components for WSCD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with WSCD1: view

Pathways for WSCD1 Gene

SuperPathways for WSCD1 Gene

No Data Available

Interacting Proteins for WSCD1 Gene

Gene Ontology (GO) - Biological Process for WSCD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with WSCD1: view

No data available for Pathways by source for WSCD1 Gene

Transcripts for WSCD1 Gene

Unigene Clusters for WSCD1 Gene

WSC domain containing 1:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for WSCD1

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for WSCD1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12
SP1:
SP2: -
SP3: -
SP4:
SP5: - -

Relevant External Links for WSCD1 Gene

GeneLoc Exon Structure for
WSCD1
ECgene alternative splicing isoforms for
WSCD1

Expression for WSCD1 Gene

mRNA expression in normal human tissues for WSCD1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for WSCD1 Gene

This gene is overexpressed in Brain - Cerebellum (4.3) and Brain - Cerebellar Hemisphere (4.2).

Protein differential expression in normal tissues for WSCD1 Gene

This gene is overexpressed in Synovial fluid (69.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for WSCD1 Gene

SOURCE GeneReport for Unigene cluster for WSCD1 Gene Hs.370166

genes like me logo Genes that share expressions with WSCD1: view

Expression partners for WSCD1 Gene

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for WSCD1 Gene

Orthologs for WSCD1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for WSCD1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia WSCD1 35
  • 88.93 (n)
  • 92.87 (a)
WSCD1 36
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia WSCD1 35
  • 85.68 (n)
  • 89.22 (a)
WSCD1 36
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Wscd1 35
  • 82.4 (n)
  • 85.84 (a)
Wscd1 16
Wscd1 36
  • 86 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia WSCD1 35
  • 98.33 (n)
  • 97.4 (a)
WSCD1 36
  • 97 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Wscd1 35
  • 82.98 (n)
  • 85.66 (a)
oppossum
(Monodelphis domestica)
Mammalia WSCD1 36
  • 76 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia WSCD1 36
  • 69 (a)
OneToOne
chicken
(Gallus gallus)
Aves WSCD1 35
  • 70.41 (n)
  • 71.4 (a)
WSCD1 36
  • 70 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 62 (a)
OneToMany
-- 36
  • 68 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia wscd1 35
  • 62.56 (n)
  • 65.54 (a)
zebrafish
(Danio rerio)
Actinopterygii Dr.12914 35
si:ch211-55a7.1 35
  • 55.83 (n)
  • 50.89 (a)
CABZ01007222.1 36
  • 65 (a)
OneToMany
WSCD1 (1 of 3) 36
  • 38 (a)
OneToMany
WSCD1 (2 of 3) 36
  • 49 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG9164 36
  • 32 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SLG1 38
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 26 (a)
OneToMany
Species with no ortholog for WSCD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for WSCD1 Gene

ENSEMBL:
Gene Tree for WSCD1 (if available)
TreeFam:
Gene Tree for WSCD1 (if available)

Paralogs for WSCD1 Gene

Paralogs for WSCD1 Gene

Selected SIMAP similar genes for WSCD1 Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with WSCD1: view

Variants for WSCD1 Gene

Sequence variations from dbSNP and Humsavar for WSCD1 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs916622 -- 6,071,286(-) ACGTA(C/T)GCTCC intron-variant
rs916625 -- 6,071,723(-) CTTTA(C/T)ATCTC intron-variant
rs1465193 -- 6,068,182(-) TCCAT(A/G)CCATC upstream-variant-2KB
rs1465194 -- 6,068,124(-) GGAAC(A/G)CCATA upstream-variant-2KB
rs1811167 -- 6,071,980(-) CCACC(A/G)CCAAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for WSCD1 Gene

Variant ID Type Subtype PubMed ID
esv26217 CNV Loss 19812545
nsv1959 CNV Loss 18451855

Relevant External Links for WSCD1 Gene

HapMap Linkage Disequilibrium report
WSCD1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WSCD1 Gene

Disorders for WSCD1 Gene

Relevant External Links for WSCD1

Genetic Association Database (GAD)
WSCD1

No disorders were found for WSCD1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for WSCD1 Gene

Publications for WSCD1 Gene

  1. Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9628581) Nagase T. … Ohara O. (DNA Res. 1998) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication. (PMID: 19460752) Yeung M.L. … Jeang K.T. (J. Biol. Chem. 2009) 3
  4. Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis. (PMID: 23740775) Xie G. … Siminovitch K.A. (Arthritis Rheum. 2013) 3
  5. Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study. (PMID: 17903297) Seshadri S. … Wolf P.A. (BMC Med. Genet. 2007) 48

Products for WSCD1 Gene

Sources for WSCD1 Gene

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