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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

WNT9A Gene

protein-coding   GIFtS: 62
GCID: GC01M228106

Wingless-Type MMTV Integration Site Family, Member 9A

(Previous names: wingless-type MMTV integration site family, member 14)
(Previous symbol: WNT14)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Wingless-Type MMTV Integration Site Family, Member 9A1 2
WNT141 2 3 5
Wingless-Type MMTV Integration Site Family, Member 141 2
Protein Wnt-9a2
Protein Wnt-143

External Ids:    HGNC: 127781   Entrez Gene: 74832   Ensembl: ENSG000001438167   OMIM: 6028635   UniProtKB: O149043   

Export aliases for WNT9A gene to outside databases

Previous GC identifers: GC01M223847 GC01M224494 GC01M225083 GC01M224415 GC01M226172 GC01M198625


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for WNT9A Gene:
The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins
have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and
patterning during embryogenesis. This gene is a member of the WNT gene family. It is expressed in gastric cancer
cell lines. The protein encoded by this gene shows 75% amino acid identity to chicken Wnt14, which has been shown
to play a central role in initiating synovial joint formation in the chick limb. This gene is clustered with
another family member, WNT3A, in the chromosome 1q42 region. (provided by RefSeq, Jul 2008)

GeneCards Summary for WNT9A Gene: 
WNT9A (wingless-type MMTV integration site family, member 9A) is a protein-coding gene. Diseases associated with WNT9A include gastric cancer, and syndactyly, and among its related super-pathways are Wnt signaling pathway and Basal cell carcinoma. GO annotations related to this gene include extracellular matrix structural constituent and G-protein coupled receptor binding. An important paralog of this gene is WNT8B.

UniProtKB/Swiss-Prot: WNT9A_HUMAN, O14904
Function: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental
protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to
signal over only few cell diameters (By similarity)

Gene Wiki entry for WNT9A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_167186.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the WNT9A gene promoter:
         E2F-4   E2F-3a   E2F-5   E2F-1   E2F   MyoD   E2F-2   Tal-1beta   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidWNT9A promoter sequence
   Search SABiosciences Chromatin IP Primers for WNT9A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WNT9A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q42   Ensembl cytogenetic band:  1q42.13   HGNC cytogenetic band: 1q42

WNT9A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WNT9A gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M228106:  view genomic region     (about GC identifiers)

Start:
228,106,357 bp from pter      End:
228,135,676 bp from pter
Size:
29,320 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: WNT9A_HUMAN, O14904 (See protein sequence)
Recommended Name: Protein Wnt-9a precursor  
Size: 365 amino acids; 40320 Da
Subcellular location: Secreted, extracellular space, extracellular matrix
Secondary accessions: A6NLW2 Q2M2J3 Q5VWU0 Q96S50

Explore the universe of human proteins at neXtProt for WNT9A: NX_O14904

Explore proteomics data for WNT9A at MOPED 

Post-translational modifications:

  • UniProtKB: Palmitoylation at Ser-221 is required for efficient binding to frizzled receptors. It is also required for
    subsequent palmitoylation at Cys-93. Palmitoylation is necessary for proper trafficking to cell surface (By
    similarity)
  • View neXtProt modification sites for NX_O14904

  • WNT9A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    WNT9A Protein Expression
    REFSEQ proteins: NP_003386.1  
    ENSEMBL proteins: 
     ENSP00000272164  
    Reactome Protein details: O14904
    Human Recombinant Protein Products for WNT9A: 
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    Novus Biologicals WNT9A Protein
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    Browse Sino Biological Cell Lysates 
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    Cloud-Clone Corp. Proteins for WNT9A 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005578proteinaceous extracellular matrix IEA--
    GO:0005615extracellular space IBA--

    WNT9A for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    WNT: Wingless-type MMTV integration sites

    4 InterPro protein domains:
     IPR026535 Wnt9
     IPR013303 Wnt9a
     IPR005817 Wnt
     IPR018161 Wnt_CS

    Graphical View of Domain Structure for InterPro Entry O14904

    ProtoNet protein and cluster: O14904

    1 Blocks protein domain: IPB005816 Secreted growth factor Wnt protein

    UniProtKB/Swiss-Prot: WNT9A_HUMAN, O14904
    Similarity: Belongs to the Wnt family


    WNT9A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: WNT9A_HUMAN, O14904
    Function: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental
    protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to
    signal over only few cell diameters (By similarity)

         Summary:

    During embryonic development, WNT9A as signaling molecule is secreted from the following cells: Interzone Cells in Autopod Synovial Joint, Interzone Cells in Stylopod Synovial Joint (see all 3).

    It affects the following cells: Articular Cartilage Cells in Autopod Articular Cartilage, Articular Cartilage Cells in Stylopod Articular Cartilage (see all 9).

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005102receptor binding ----
    GO:0005109frizzled binding IBA--
    GO:0005201extracellular matrix structural constituent NAS--
    GO:0005515protein binding ----
         
    WNT9A for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for WNT9A:
     Decreased influenza A H1N1 (A/  Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r  Synthetic lethal with Ras 

         4 MGI mutant phenotypes (inferred from 4 alleles(MGI details for Wnt9a):
     craniofacial  mortality/aging  no phenotypic analysis  skeleton 

    WNT9A for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for WNT9A: Wnt9atm1.1Chha Wnt9atm1Lex

       inGenious Targeting Laboratory - Custom generated mouse model solutions for WNT9A 
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for WNT9A About   (see all 11)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Wnt signaling pathway
    Wnt signaling pathway0.40
    Wnt Signaling Pathway NetPath0.37
    Wnt Signaling Pathway0.40
    2Basal cell carcinoma
    Hedgehog signaling pathway0.43
    Wnt Pathway0.39
    Basal cell carcinoma0.43
    Melanogenesis0.32
    3Signaling by GPCR
    Signaling by GPCR0.90
    Signal Transduction0.55
    4Asparagine N-linked glycosylation
    WNT ligand biogenesis and trafficking0.77
    Signaling by Wnt0.62
    5Transcription Androgen Receptor nuclear signaling
    Translation Non-genomic (rapid) action of Androgen Receptor0.49
    Transcription Androgen Receptor nuclear signaling0.49

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    2 EMD Millipore Pathways for WNT9A
        Transcription Androgen Receptor nuclear signaling
    Translation Non-genomic (rapid) action of Androgen Receptor

    1 R&D Systems Pathway for WNT9A
        Wnt Signaling Pathway


    1 Tocris Bioscience Pathway for WNT9A
        Wnt Pathway

    2 GeneGo (Thomson Reuters) Pathways for WNT9A
        Transcription Androgen Receptor nuclear signaling
    Translation Non-genomic (rapid) action of Androgen Receptor

    1 BioSystems Pathway for WNT9A
        Wnt Signaling Pathway NetPath


    5/6        Reactome Pathways for WNT9A (see all 6)
        Signaling by Wnt
    Signal Transduction
    Signaling by GPCR
    WNT ligand biogenesis and trafficking
    GPCR ligand binding


    5/8         Kegg Pathways  (Kegg details for WNT9A) (see all 8):
        Wnt signaling pathway
    Hedgehog signaling pathway
    Hippo signaling pathway
    Melanogenesis
    HTLV-I infection


    WNT9A for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for WNT9A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

    5/20 Interacting proteins for WNT9A (O149043 ENSP000002721644) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CTNNB1P352223I2D: score=1 
    IFIT3O148793I2D: score=1 
    WNT4P567053I2D: score=1 
    CER1ENSP000003702974STRING: ENSP00000370297
    FZD1ENSP000002879344STRING: ENSP00000287934
    About this table

    Gene Ontology (GO): 5/21 biological process terms (GO ID links to tree view) (see all 21):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007093mitotic cell cycle checkpoint IMP17351820
    GO:0007267cell-cell signaling NAS9441749
    GO:0007275multicellular organismal development NAS9441749
    GO:0008285negative regulation of cell proliferation IMP17351820
    GO:0016055Wnt receptor signaling pathway IBA--

    WNT9A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    EMD Millipore small molecules for WNT9A:
    Small Molecule - inhibitor
    Browse drugs & compounds from Enzo Life Sciences

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    Search CenterWatch for drugs/clinical trials and news about WNT9A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for WNT9A gene: 
    NM_003395.2  

    Unigene Cluster for WNT9A:

    Wingless-type MMTV integration site family, member 9A
    Hs.149504  [show with all ESTs]
    Unigene Representative Sequence: AK131041
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000272164(uc001hri.2) ENST00000497852
    miRNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WNT9A
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    Additional mRNA sequence: 

    AB060283.1 AK131041.1 BC111960.1 BC113431.1 

    2 DOTS entries:

    DT.75100574  DT.95208502 

    18 AceView cDNA sequences:

    CB850782 AI280246 AI206806 AW628030 BE220265 AI914125 BP342331 AI784076 
    AB060283 AI989854 AK131041 BX118140 BF222744 AW470939 NM_003395 BE218087 
    AW628384 AA211273 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    WNT9A expression in normal human tissues (normalized intensities)      WNT9A embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CGCTTCTCTT
    WNT9A Expression
    About this image


    WNT9A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/13 selected tissues (see all 13) fully expand
     
     Cartilage (Muscoskeletal System)    fully expand to see all 9 entries
             Central Intermediate Lamina Cells Zeugopod Synovial Joint
     
     Limb (Muscoskeletal System)    fully expand to see all 8 entries
             Central Intermediate Lamina Cells Zeugopod Synovial Joint
             limb/hindlimb   
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
             brain/midbrain   
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             Mesencephalic Floor Plate
     
     Hypoblast (Extraembryonic Tissues)
             Hypoblast Cells Hypoblast

    See WNT9A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for WNT9A

    SOURCE GeneReport for Unigene cluster: Hs.149504
        SABiosciences Expression via Pathway-Focused PCR Arrays including WNT9A: 
              Hedgehog Signaling Pathway in human mouse rat
              WNT Signaling Targets in human mouse rat
              WNT Signaling Pathway in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WNT9A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for WNT9A gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Wnt9a1 , 5 wingless-type MMTV integration site 9A1, 5 89.13(n)1
    98.08(a)1
      11 (37.55 cM)5
    2167951  NM_139298.21  NP_647459.11 
     593069285 
    chicken
    (Gallus gallus)
    Aves WNT9A1 wingless-type MMTV integration site family, member more 77.87(n)
    85.22(a)
      395829  NM_204981.1  NP_990312.1 
    lizard
    (Anolis carolinensis)
    Reptilia WNT9A6
    Protein Wnt
    81(a)
    1 ↔ 1
    GL343853.1(113172-126817)
    zebrafish
    (Danio rerio)
    Actinopterygii wnt9a1 wingless-type MMTV integration site family, member more 73.21(n)
    74.54(a)
      751644  NM_001045363.1  NP_001038828.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Wnt46
    Wnt oncogene analog 4
    19(a)
    1 → many
    2L(7255460-7277168)


    ENSEMBL Gene Tree for WNT9A (if available)
    TreeFam Gene Tree for WNT9A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for WNT9A gene
    WNT8B2  WNT8A2  WNT9B2  
    15 SIMAP similar genes for WNT9A using alignment to 2 protein entries:     WNT9A_HUMAN (see all proteins):
    WNT9B    WNT4    WNT2B    WNT7B    WNT8B    WNT2
    WNT16    WNT5A    WNT1    WNT7A    WNT8A    WNT5B
    WNT6    WNT11    WNT3

    WNT9A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/584 SNPs in WNT9A are shown (see all 584)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1127031571,2
    C,Funtested1228109696(-) GTGATC/TAAGGC 2 I syn14Minor allele frequency- T:0.02NS WA NA EU 5041
    rs1418094101,2
    --228108687(+) GCCCCA/GACGTG 1 -- ds50010--------
    rs109162441,2
    C,F,A,H--228108703(+) AAAGCC/TTCTCA 1 -- ds5001 ese319Minor allele frequency- T:0.25NS EA NA WA 2814
    rs776251741,2
    C,F--228108709(+) TCTCAG/TTCCTT 1 -- ds50016Minor allele frequency- T:0.09CSA NS WA NA EA 818
    rs1133995061,2
    C,F--228108779(-) TCCCCG/AGGCCT 1 -- ds50011Minor allele frequency- A:0.01NS 428
    rs1816917721,2
    --228108780(+) GGCCCA/GGGGAC 1 -- ds50010--------
    rs1860387751,2
    --228108796(+) CCTTGC/TAGGTG 1 -- ds50010--------
    rs1128494051,2
    C,F--228108897(-) CACACG/AGTGTG 1 -- ds50012Minor allele frequency- A:0.01NS WA 548
    rs37957671,2
    C,F,A--228108932(+) GGCTGG/ACTGGG 1 -- ds500110Minor allele frequency- A:0.38NA CSA NS WA EA 795
    rs1998474561,2
    --228109070(+) ATGCA-/GGTGTA 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for WNT9A (228106357 - 228135676 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for WNT9A:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv523935CNV Loss19592680
    nsv516409CNV Loss19592680
    nsv826931CNV Loss20364138
    nsv873249CNV Loss21882294
    nsv873250CNV Loss21882294
    nsv873251CNV Loss21882294
    nsv826920CNV Gain20364138
    nsv826942CNV Gain20364138
    esv32853CNV Gain17666407
    nsv826908CNV Gain20364138

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 602863    OMIM disorders: --

    7 diseases for WNT9A:    About MalaCards
    gastric cancer    syndactyly    basal cell carcinoma    chronic lymphocytic leukemia
    pancreatic cancer    leukemia    pancreatitis


    WNT9A for disorders           About GeneDecksing

    6 Novoseek inferred disease relationships for WNT9A gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    gastric cancer 49.7 4 11713592 (2), 11414706 (1), 15809769 (1)
    pancreatic cancer 49.2 3 11713592 (2), 15809769 (1)
    breast cancer 19.3 4 11713592 (3), 15809769 (1)
    cancer 16.1 6 11713592 (3), 11414706 (1), 15809769 (1)
    necrosis 2.93 1 11713592 (1)
    tumors 0 1 11713592 (1)

    Genetic Association Database (GAD): WNT9A
    Human Genome Epidemiology (HuGE) Navigator: WNT9A (3 documents)

    Export disorders for WNT9A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for WNT9A gene, integrated from 9 sources (see all 24):
    (articles sorted by number of sources associating them with WNT9A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation of two novel WNT genes, WNT14 and WNT15, one of which (WNT15) is closely linked to WNT3 on human chromosome 17q21. (PubMed id 9441749)1, 2, 3 Bergstein I.... Brown A.M.C. (1997)
    2. Molecular cloning and characterization of WNT3a and WNT14 clustered in human chromosome 1q42 region. (PubMed id 11414706)1, 2, 9 Saitoh T.... Katoh M. (2001)
    3. Association between polymorphisms in Wnt signaling pa thway genes and bone mineral density in postmenopausal Korean women. (PubMed id 20613673)1, 4 Lee D.Y....Kim J.G. (2010)
    4. High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. (PubMed id 19453261)1, 4 Yerges L.M....Zmuda J.M. (2009)
    5. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Comparative genomics on Wnt9a orthologs. (PubMed id 15809769)1, 9 Katoh Y. and Katoh M. (2005)
    8. Molecular cloning and expression of mouse Wnt14, and structural comparison between mouse Wnt14-Wnt3a gene cluster and human WNT14-WNT3A gene cluster. (PubMed id 11836627)1, 9 Katoh M. (2002)
    9. Expression patterns of Wnt genes during development of an anterior part of the chicken eye. (PubMed id 16258938)1, 9 Fokina V.M. and Frolova E.I. (2006)
    10. Distinct requirements for wnt9a and irf6 in extension and integration mechanisms during zebrafish palate morphogenesis. (PubMed id 23154410)1 Dougherty M....Liao E.C. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7483 HGNC: 12778 AceView: WNT9A Ensembl:ENSG00000143816 euGenes: HUgn7483
    ECgene: WNT9A Kegg: 7483 H-InvDB: WNT9A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for WNT9A Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for WNT9A Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for WNT9A gene:
    Search GeneIP for patents involving WNT9A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

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