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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

WNT8B Gene

protein-coding   GIFtS: 61
GCID: GC10P102212

Wingless-Type MMTV Integration Site Family, Member 8B

Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Wingless-Type MMTV Integration Site Family, Member 8B1 2
Protein Wnt-8b2

External Ids:    HGNC: 127891   Entrez Gene: 74792   Ensembl: ENSG000000752907   OMIM: 6013965   UniProtKB: Q930983   

Export aliases for WNT8B gene to outside databases

Previous GC identifers: GC10P101116 GC10P101456 GC10P102354 GC10P101887 GC10P095851


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for WNT8B Gene:
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These
proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell
fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein
which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins,
respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the
developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial
epilepsy. (provided by RefSeq, Jul 2008)

GeneCards Summary for WNT8B Gene: 
WNT8B (wingless-type MMTV integration site family, member 8B) is a protein-coding gene. Diseases associated with WNT8B include polydactyly, and basal cell carcinoma, and among its related super-pathways are Basal cell carcinoma and Wnt signaling pathway. GO annotations related to this gene include G-protein coupled receptor binding. An important paralog of this gene is WNT8A.

UniProtKB/Swiss-Prot: WNT8B_HUMAN, Q93098
Function: Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role
in the development and differentiation of certain forebrain structures, notably the hippocampus

Gene Wiki entry for WNT8B Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NC_018921.2  NT_030059.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the WNT8B gene promoter:
         Oct-B1   POU2F2 (Oct-2.1)   oct-B3   oct-B2   GATA-3   POU2F2   POU2F2C   POU2F1   POU2F1a   POU2F2B   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidWNT8B promoter sequence
   Search SABiosciences Chromatin IP Primers for WNT8B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WNT8B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q24   Ensembl cytogenetic band:  10q24.31   HGNC cytogenetic band: 10q24

WNT8B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WNT8B gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P102212:  view genomic region     (about GC identifiers)

Start:
102,222,798 bp from pter      End:
102,243,501 bp from pter
Size:
20,704 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: WNT8B_HUMAN, Q93098 (See protein sequence)
Recommended Name: Protein Wnt-8b precursor  
Size: 351 amino acids; 38721 Da
Subcellular location: Secreted, extracellular space, extracellular matrix
Secondary accessions: O00771 Q5VX55 Q8WYK9

Explore the universe of human proteins at neXtProt for WNT8B: NX_Q93098

Explore proteomics data for WNT8B at MOPED 

WNT8B Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

WNT8B Protein Expression

REFSEQ proteins: NP_003384.2  
ENSEMBL proteins: 
 ENSP00000340677  
Reactome Protein details: Q93098
Human Recombinant Protein Products for WNT8B: 
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Novus Biologicals WNT8B Lysate
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Browse Sino Biological Cell Lysates 
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for WNT8B 

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005576extracellular region TAS--
GO:0005578proteinaceous extracellular matrix IEA--
GO:0005615extracellular space IBA--

WNT8B for ontologies           About GeneDecksing



WNT8B Antibody Products: 
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Cloud-Clone Corp. ELISAs for WNT8B 
Cloud-Clone Corp. CLIAs for WNT8B


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
HGNC Gene Families: 
WNT: Wingless-type MMTV integration sites

3 InterPro protein domains:
 IPR013301 Wnt8
 IPR005817 Wnt
 IPR018161 Wnt_CS

Graphical View of Domain Structure for InterPro Entry Q93098

ProtoNet protein and cluster: Q93098

1 Blocks protein domain: IPB005816 Secreted growth factor Wnt protein

UniProtKB/Swiss-Prot: WNT8B_HUMAN, Q93098
Similarity: Belongs to the Wnt family


WNT8B for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: WNT8B_HUMAN, Q93098
Function: Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role
in the development and differentiation of certain forebrain structures, notably the hippocampus

     Genatlas biochemistry entry for WNT8B:
wingless-type MMTV integration site 8B,member of the WNT family encoding intercellular signaling
molecules,expressed in the developing forebrain,Drosophila wingless (Wg) segment polarity gene homolog,modulating
cell fate and cell behavior during vertebrate development

     Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005102receptor binding ----
GO:0005109frizzled binding IBA--
     
WNT8B for ontologies           About GeneDecksing


Phenotypes:
     1 MGI mutant phenotype (inferred from 1 allele(MGI details for Wnt8b):
 nervous system 

WNT8B for phenotypes           About GeneDecksing

Animal Models:
     MGI mouse knock-out Wnt8btm1Jmas for WNT8B

   inGenious Targeting Laboratory - Custom generated mouse model solutions for WNT8B 
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miRNA
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Inhib. RNA
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Gene Editing
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Sirion Biotech Customized adenovirus for overexpression of WNT8B

Clone
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OriGene clones in human, mouse for WNT8B (see all 7)
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GenScript: all cDNA clones in your preferred vector: WNT8B (NM_003393)
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Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WNT8B


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for WNT8B About   (see all 17)                                                                                              See pathways by source

SuperPathContained pathways About
1Basal cell carcinoma
Hedgehog signaling pathway0.43
Wnt Pathway0.39
Basal cell carcinoma0.43
Melanogenesis0.32
2Wnt signaling pathway
Wnt signaling pathway0.40
Wnt Signaling Pathway0.40
3Signaling by GPCR
Signaling by GPCR0.90
Signal Transduction0.55
4Asparagine N-linked glycosylation
WNT ligand biogenesis and trafficking0.77
Signaling by Wnt0.62
5Nanog in Mammalian ESC Pluripotency
Nanog in Mammalian ESC Pluripotency0.61
GSK3 Signaling0.61

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways

2 EMD Millipore Pathways for WNT8B
    Transcription Androgen Receptor nuclear signaling
Translation Non-genomic (rapid) action of Androgen Receptor

1 R&D Systems Pathway for WNT8B
    Wnt Signaling Pathway

5/8 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for WNT8B (see all 8)
    GSK3 Signaling
Factors Promoting Cardiogenesis in Vertebrates
Presenilin-Mediated Signaling
Human Embryonic Stem Cell Pluripotency
Colorectal Cancer Metastasis

1 Tocris Bioscience Pathway for WNT8B
    Wnt Pathway

2 GeneGo (Thomson Reuters) Pathways for WNT8B
    Transcription Androgen Receptor nuclear signaling
Translation Non-genomic (rapid) action of Androgen Receptor

5/6        Reactome Pathways for WNT8B (see all 6)
    Signaling by Wnt
Signal Transduction
Signaling by GPCR
WNT ligand biogenesis and trafficking
GPCR ligand binding


5/8         Kegg Pathways  (Kegg details for WNT8B) (see all 8):
    Wnt signaling pathway
Hedgehog signaling pathway
Hippo signaling pathway
Melanogenesis
HTLV-I infection


WNT8B for pathways           About GeneDecksing

Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for WNT8B

STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

5/17 Interacting proteins for WNT8B (ENSP000003406774) via UniProtKB, MINT, STRING, and/or I2D (see all 17)
InteractantInteraction Details
GeneCardExternal ID(s)
CER1ENSP000003702974STRING: ENSP00000370297
FZD1ENSP000002879344STRING: ENSP00000287934
FZD10ENSP000002290304STRING: ENSP00000229030
FZD2ENSP000003239014STRING: ENSP00000323901
FZD3ENSP000002400934STRING: ENSP00000240093
About this table

Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0007165signal transduction TAS9536085
GO:0007275multicellular organismal development ----
GO:0007369gastrulation ISS7635061
GO:0007399nervous system development TAS9536085
GO:0010628positive regulation of gene expression IEA--

WNT8B for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
EMD Millipore small molecules for WNT8B:
Small Molecule - inhibitor
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for WNT8B

Search CenterWatch for drugs/clinical trials and news about WNT8B

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for WNT8B gene: 
NM_003393.3  

Unigene Cluster for WNT8B:

Wingless-type MMTV integration site family, member 8B
Hs.421281  [show with all ESTs]
Unigene Representative Sequence: Y11094
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000343737(uc001krb.3)

miRNA
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Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for WNT8B
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat WNT8B
Clone
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GenScript: all cDNA clones in your preferred vector: WNT8B (NM_003393)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for WNT8B
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WNT8B
Sirion Biotech Customized lentivirus for stable overexpression of WNT8B 
                     Customized lentivirus expression plasmids for stable overexpression of WNT8B 
Primer
Products:
    
OriGene qPCR primer pairs and template standards for WNT8B
OriGene qSTAR qPCR primer pairs in human, mouse for WNT8B
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat WNT8B
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WNT8B
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WNT8B

Additional mRNA sequence: 

AB073637.1 X91940.1 Y11094.1 

1 DOTS entry:

DT.91705411 

7 AceView cDNA sequences:

AB073637 BF732616 X91940 Y11094 BF354999 NM_003393 BX279669 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

WNT8B expression in normal human tissues (normalized intensities)      WNT8B embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: AATGGACTTT
WNT8B Expression
About this image


WNT8B expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database 
 5/6 selected tissues (see all 6) fully expand
 
 Brain (Nervous System)    fully expand to see all 20 entries
         Choroid Plexus Progenitor Cells Choroid Plexus
         Thalamus
         Olfactory Bulb   
 
 Neural Tube (Nervous System)    fully expand to see all 4 entries
         Telencephalon
 
 Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
         Mononuclear Myocytes Hyoid Arch Muscles
 
 Spinal Cord (Nervous System)
         Dorsal Horn   
 
 Choroid Plexus (Nervous System)
         Choroid Plexus Progenitor Cells Choroid Plexus

See WNT8B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for WNT8B

SOURCE GeneReport for Unigene cluster: Hs.421281

UniProtKB/Swiss-Prot: WNT8B_HUMAN, Q93098
Tissue specificity: Expression is restricted to the brain, and more specifically to the forebrain

    SABiosciences Expression via Pathway-Focused PCR Arrays including WNT8B: 
          Hedgehog Signaling Pathway in human mouse rat
          WNT Signaling Pathway in human mouse rat

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QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WNT8B
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WNT8B

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for WNT8B gene from 7/14 species (see all 14)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Wnt8b1 , 5 wingless related MMTV integration site 8b1, 5 89.08(n)1
96.55(a)1
  19 (37.98 cM)5
224231  NM_011720.31  NP_035850.21 
 444934725 
chicken
(Gallus gallus)
Aves WNT8B1 wingless-type MMTV integration site family, member more 81.24(n)
91.74(a)
  428953  XM_426508.2  XP_426508.2 
lizard
(Anolis carolinensis)
Reptilia WNT8B6
wingless-type MMTV integration site family, member...
84(a)
1 ↔ 1
GL343388.1(202405-226057)
African clawed frog
(Xenopus laevis)
Amphibia Xwnt-8b2 Xwnt-8b protein 78.21(n)    U22173.1 
zebrafish
(Danio rerio)
Actinopterygii wnt8b2 wnt8b 82.19(n)   30144  U10870.1 
fruit fly
(Drosophila melanogaster)
Insecta wntD6
wnt inhibitor of Dorsal
24(a)
1 → many
3R(9117774-9118920)
worm
(Caenorhabditis elegans)
Secernentea lin-446
Abnormal cell lineage protein 44
23(a)
1 → many
I(4126056-4129307)


ENSEMBL Gene Tree for WNT8B (if available)
TreeFam Gene Tree for WNT8B (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for WNT8B gene
WNT8A2  WNT9B2  WNT9A2  
16 SIMAP similar genes for WNT8B using alignment to 1 protein entry:     WNT8B_HUMAN:
WNT8A    WNT2    WNT4    WNT5B    WNT2B    WNT5A
WNT9A    WNT7B    WNT9B    WNT1    WNT16    WNT11
WNT7A    WNT3    WNT3A    WNT6

WNT8B for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/438 SNPs in WNT8B are shown (see all 438)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 10 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
VAR_0362884
A colorectal cancer sample4--see VAR_0362882 E Q mis40--------
rs1926215501,2
--102220935(+) TGCCCA/GAATCT 1 -- us2k10--------
rs1505154431,2
--102220950(+) TACCTC/TCCAAT 1 -- us2k10--------
rs1855746111,2
--102220967(+) TTGCAC/TCCCTT 1 -- us2k10--------
rs49194641,2
C,F,A--102221195(+) CAAATA/GAAGAC 1 -- us2k111Minor allele frequency- G:0.16NA CSA WA EA 510
rs1383096331,2
--102221217(+) GATTCC/TATGTG 1 -- us2k10--------
rs1904803861,2
--102221271(+) TAAATC/TGTCTG 1 -- us2k10--------
rs1496496591,2
--102221375(+) TAAAAC/GAAAAG 1 -- us2k10--------
rs1930884741,2
--102221380(+) GAAAAG/TAACAA 1 -- us2k10--------
rs1847204021,2
--102221401(+) CTCAGA/GGAGAC 1 -- us2k10--------

HapMap Linkage Disequilibrium report for WNT8B (102222798 - 102243501 bp)

Structural Variations
     Database of Genomic Variants (DGV) 10 variations for WNT8B:    About this table     
Variant IDTypeSubtypePubMed ID
nsv819434CNV Loss19587683
nsv831963CNV Loss17160897
dgv811n71CNV Loss21882294
nsv895957CNV Gain21882294
nsv818783CNV Gain17921354
esv34217CNV Gain17911159
nsv831962CNV Gain17160897
nsv8723CNV Gain18304495
essv24916CNV CNV17122850
dgv318e1CNV Complex17122850

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SeqTarget long-range PCR primers for resequencing WNT8B
DNA2.0 Custom Variant and Variant Library Synthesis for WNT8B

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 601396    OMIM disorders: --

6 diseases for WNT8B:    About MalaCards
polydactyly    basal cell carcinoma    gastric cancer    alzheimer's disease
colorectal cancer    neuronitis


WNT8B for disorders           About GeneDecksing


Congresses - knowledge worth sharing:  
Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
Genetic Association Database (GAD): WNT8B
Human Genome Epidemiology (HuGE) Navigator: WNT8B (3 documents)

Export disorders for WNT8B gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for WNT8B gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with WNT8B)
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  1. Isolation and characterization of WNT8B, a novel human Wnt gene that maps to 10q24. (PubMed id 8661156)1, 2, 3, 9 Lako M.... Lindsay S. (1996)
  2. Up-regulation of WNT8B mRNA in human gastric cancer. (PubMed id 11788899)1, 2, 9 Saitoh T.... Katoh M. (2002)
  3. A novel mammalian Wnt gene, WNT8B, shows brain-restricted expression in early development, with sharply delimited expression boundaries in the developing forebrain. (PubMed id 9536085)1, 2, 9 Lako M.... Strachan T. (1998)
  4. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (2006)
  5. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
  6. Genome-wide association study identifies novel loci as sociated with concentrations of four plasma phospholipid fatty acids in the de n ovo lipogenesis pathway: results from the Cohorts for Heart and Aging Research i n Genomic Epidemiology (CHARGE) consortium. (PubMed id 23362303)1 Wu J.H....Mozaffarian D. (2013)
  7. Single-nucleotide polymorphisms, acute rejection, and severity of tubulitis in kidney transplantation, accounting for center-to-center variation. (PubMed id 21085059)4 Israni A....Oetting W.S. (2010)
  8. [Mutation and expression of WNT8b gene and SHH gene i n Hirschprung disease]. (PubMed id 20972907)1 Gao H....Wang W.L. (2010)
  9. Conserved POU/OCT- and GATA-binding sites in 5'-flanking promoter region of mammalian WNT8B orthologs. (PubMed id 17390031)1 Katoh M. and Katoh M. (2007)
  10. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 7479 HGNC: 12789 AceView: WNT8B Ensembl:ENSG00000075290 euGenes: HUgn7479
ECgene: WNT8B Kegg: 7479 H-InvDB: WNT8B

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for WNT8B Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for WNT8B Genetics and Cytogenetics in Oncology and Haematology

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for WNT8B gene:
Search GeneIP for patents involving WNT8B

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