Aliases for WNT6 Gene
Aliases for WNT6 Gene
External Ids for WNT6 Gene
- HGNC: 12785
- Entrez Gene: 7475
- Ensembl: ENSG00000115596
- OMIM: 604663
- UniProtKB: Q9Y6F9
Previous GeneCards Identifiers for WNT6 Gene
- GC02P217740
- GC02P218445
- GC02P219688
- GC02P219927
- GC02P219548
- GC02P219432
- GC02P219724
- GC02P211579
Summaries for WNT6 Gene
-
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level. [provided by RefSeq, Jul 2008]
GeneCards Summary for WNT6 Gene
WNT6 (Wnt Family Member 6) is a Protein Coding gene. Among its related pathways are LncRNA-mediated mechanisms of therapeutic resistance and Wnt Signaling Pathways: beta-Catenin-independent Wnt/Ca2+ Signaling and Other Non-canonical Wnt Signaling Pathways. GO annotations related to this gene include receptor binding and frizzled binding. An important paralog of this gene is WNT1.
UniProtKB/Swiss-Prot for WNT6 Gene
-
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Together with CAV1 may promote chemoresistance of gastric cancer cells to DNA-damaging anthracycline drugs through the activation of the canonical Wnt receptor signaling pathway.
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WNT6 Gene
Genomics for WNT6 Gene
Regulatory Elements for WNT6 Gene
Enhancers for WNT6 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around WNT6 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the WNT6 gene promoter:
Regulatory Element Products
Genomic Location for WNT6 Gene
- Chromosome:
- 2
- Start:
- 218,859,821 bp from pter
- End:
- 218,874,233 bp from pter
- Size:
- 14,413 bases
- Orientation:
- Plus strand
Genomic View for WNT6 Gene
Genes around WNT6 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q35 by Ensembl
- 2q35 by Entrez Gene
- 2q35 by HGNC
WNT6 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for WNT6 Gene
Proteins for WNT6 Gene
-
Protein details for WNT6 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y6F9-WNT6_HUMAN
- Recommended name:
- Protein Wnt-6
- Protein Accession:
- Q9Y6F9
- Q9H1J6
- Q9H238
Protein attributes for WNT6 Gene
- Size:
- 365 amino acids
- Molecular mass:
- 39721 Da
- Quaternary structure:
-
- Interacts with PORCN.
Protein Expression for WNT6 Gene
Post-translational modifications for WNT6 Gene
- Palmitoleylation is required for efficient binding to frizzled receptors. Depalmitoleylation leads to Wnt signaling pathway inhibition.
- Glycosylation at isoforms=86 and posLast=311311
- Modification sites at PhosphoSitePlus
Other Protein References for WNT6 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for WNT6 (Wnt-6)
-
Custom Antibody ServicesOriGene Antibodies for WNT6
- Novus Biologicals Antibodies for WNT6
- Invitrogen Antibodies for WNT6
- antibodies-online Antibodies for WNT6: See all 62
- GeneTex WNT6 antibody for WNT6
Protein Products
-
OriGene Purified Proteins for WNT6
- Search Origene for MassSpec and Protein Over-expression Lysates for WNT6
- Origene Custom Protein Services for WNT6
- antibodies-online Proteins for WNT6: See all 3
- Search antibodies-online for peptides
- Search GeneTex for Proteins for WNT6
Assay Products
- antibodies-online Kits for WNT6: See all 4
No data available for DME Specific Peptides for WNT6 Gene
Domains & Families for WNT6 Gene
Gene Families for WNT6 Gene
- HGNC:
Protein Domains for WNT6 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for WNT6 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9Y6F9- Family:
-
- Belongs to the Wnt family.
Function for WNT6 Gene
Molecular function for WNT6 Gene
- GENATLAS Biochemistry:
- wingless-type MMTV integration site 6,Drosophila wingless (wg) segment polarity gene homolog,expressed in ectoderm,somites,limb and mammary gland in mice,involved in short-range signaling during embryonic patterning
- UniProtKB/Swiss-Prot Function:
- Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Together with CAV1 may promote chemoresistance of gastric cancer cells to DNA-damaging anthracycline drugs through the activation of the canonical Wnt receptor signaling pathway.
LifeMap Function Summary for WNT6 Gene
During embryonic development, WNT6 as signaling molecule is secreted from the following cells
- Surface Ectoderm
It affects the following cells:
- Brain
- Paraxial Mesoderm
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005102 | receptor binding | IEA | -- |
| GO:0005109 | frizzled binding | IBA | -- |
Phenotypes for WNT6 Gene
- MGI mutant phenotypes for WNT6:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for WNT6:
Animal Model Products
-
Taconic Biosciences Mouse Models for WNT6
- Cyagen custom Knockout/knockin (KOKI) mouse models for WNT6
-
-
ViGene Biosciences lentiviral particle packaged cDNA for WNT6 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for WNT6 gene
- Search ViGene Biosciences for WNT6
CRISPR Products
-
OriGene CRISPR knockouts for WNT6
-
Santa Cruz Biotechnology (SCBT) CRISPR for WNT6
- GenScript: Design CRISPR guide RNA sequences for WNT6
miRNA for WNT6 Gene
- miRTarBase miRNAs that target WNT6
miRNA Products
- Search ViGene Biosciences for WNT6
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for WNT6
- Browse OriGene Inhibitory RNA Products For WNT6
-
ViGene Biosciences ready-to-package AAV shRNAs for WNT6 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for WNT6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for WNT6
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for WNT6
-
ViGene Biosciences adenoviral particle packaged cDNA for WNT6 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for WNT6 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for WNT6 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for WNT6 Gene
Localization for WNT6 Gene
Subcellular locations from UniProtKB/Swiss-Prot for WNT6 Gene
- Secreted, extracellular space, extracellular matrix.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| golgi apparatus | 5 |
| plasma membrane | 4 |
| endoplasmic reticulum | 4 |
| nucleus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005578 | proteinaceous extracellular matrix | IEA | -- |
| GO:0005615 | extracellular space | IBA | -- |
| GO:0005788 | endoplasmic reticulum lumen | TAS | -- |
| GO:0005796 | Golgi lumen | TAS | -- |
Pathways & Interactions for WNT6 Gene
Pathways by source for WNT6 Gene
2 Sino Biological pathways for WNT6 Gene
2 GeneTex pathways for WNT6 Gene
4 BioSystems pathways for WNT6 Gene
6 Reactome pathways for WNT6 Gene
10 KEGG pathways for WNT6 Gene
2 GeneGo (Thomson Reuters) pathways for WNT6 Gene
4 R&D Systems pathways for WNT6 Gene
1 Tocris pathway for WNT6 Gene
7 Qiagen pathways for WNT6 Gene
Interacting Proteins for WNT6 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001658 | branching involved in ureteric bud morphogenesis | IEA | -- |
| GO:0007275 | multicellular organism development | IEA | -- |
| GO:0009798 | axis specification | IEA | -- |
| GO:0010628 | positive regulation of gene expression | IMP | 20113781 |
| GO:0016055 | Wnt signaling pathway | TAS | -- |
Transcripts for WNT6 Gene
mRNA/cDNA for WNT6 Gene
- (1) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (28) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for WNT6 Gene
CRISPR Products
-
OriGene CRISPR knockouts for WNT6
-
Santa Cruz Biotechnology (SCBT) CRISPR for WNT6
- GenScript: Design CRISPR guide RNA sequences for WNT6
miRNA Products
- Search ViGene Biosciences for WNT6
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for WNT6
- Browse OriGene Inhibitory RNA Products For WNT6
-
ViGene Biosciences ready-to-package AAV shRNAs for WNT6 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for WNT6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for WNT6
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for WNT6 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Tooth (Integumentary System)
- Dental Placode Cells Dental Placode
- Primary Enamel Knot Cells Enamel Knot
- Inner Enamel Epithelial Cells Dental Enamel
- Outer Enamel Epithelial Cells Dental Enamel
- Dental Enamel
-
Epithelial Cells
- Dental Placode Cells Dental Placode
- Inner Enamel Epithelial Cells Dental Enamel
- Outer Enamel Epithelial Cells Dental Enamel
- Primary Hair Placode Cells Hair Follicle
- Intermediate Keratinocytes Embryonic Epidermis
-
Kidney (Urinary System)
- Ureteric Bud Tip Cells Ureteric Bud
- Ureteric Bud
-
Hair (Integumentary System)
- Primary Hair Placode Cells Hair Follicle
- Basal Keratinocytes Embryonic Epidermis
-
Epidermis (Integumentary System)
- Intermediate Keratinocytes Embryonic Epidermis
- Basal Keratinocytes Embryonic Epidermis
-
Limb (Muscoskeletal System)
- Apical Ectodermal Ridge Cells Limb Ectoderm
-
Ectoderm (Gastrulation Derivatives)
- Apical Ectodermal Ridge Cells Limb Ectoderm
-
Peripheral Nervous System (Nervous System)
- Immature Schwann Cells Peripheral Nerve Domain
-
Hypoblast (Extraembryonic Tissues)
- Hypoblast Cells Hypoblast
- Gut Tube (Gastrointestinal Tract)
- Dermis (Integumentary System)
-
Heart (Cardiovascular System)
mRNA differential expression in normal tissues according to GTEx for WNT6 Gene
This gene is overexpressed in Nerve - Tibial (x8.4).
This gene is overexpressed in Spinal cord (27.6), Testis (19.1), Placenta (9.8), and Ovary (7.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for WNT6 Gene
NURSA nuclear receptor signaling pathways regulating expression of WNT6 Gene:
WNT6SOURCE GeneReport for Unigene cluster for WNT6 Gene:
Hs.29764mRNA Expression by UniProt/SwissProt for WNT6 Gene:
Q9Y6F9-WNT6_HUMAN
Tissue specificity:
Expressed in gastric cancer cell lines and gastric cancer tissues (at protein level). Detected in the apical gland region of the gastric foveolar epithelium (at protein level).
Primer Products
-
OriGene qPCR primer pairs and template standards for WNT6
-
OriGene qPCR primer pairs for WNT6
No data available for Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for WNT6 Gene
Orthologs for WNT6 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | WNT6 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | WNT6 35 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | WNT6 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | WNT6 34 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | WNT6 35 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Wnt6 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Wnt6 34 |
|
||
| chicken (Gallus gallus) |
Aves | WNT6 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | WNT6 35 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | wnt6b 34 35 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP009733 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | Wnt6 36 34 35 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | cwn-1 35 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
ManyToMany |
- Species where no ortholog for WNT6 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Paralogs for WNT6 Gene
Paralogs for WNT6 Gene
(18) SIMAP similar genes for WNT6 Gene using alignment to 2 proteins:
Variants for WNT6 Gene
| SNP ID | Clin | Chr 02 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs786205888 | Likely benign | 218,871,753(+) | GCGCG(A/G)CACAA | reference, synonymous-codon | |
| rs1000805740 | -- | 218,870,565(+) | CTTGT(G/T)GTCCA | intron-variant | |
| rs1000900154 | -- | 218,861,142(+) | CCCCA(C/G)ATTTG | intron-variant | |
| rs1000925958 | -- | 218,861,510(+) | GACCT(C/T)AGGAG | intron-variant | |
| rs1000939744 | -- | 218,870,300(+) | CAACA(A/G)TGCTT | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv7296n54 | CNV | loss | 21841781 |
| nsv1072496 | CNV | deletion | 25765185 |
| nsv834542 | CNV | gain | 17160897 |
| nsv954838 | CNV | deletion | 24416366 |
Gene Damage Index Score:
3.13;
51.35% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for WNT6 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WNT6 Gene
Disorders for WNT6 Gene
Relevant External Links for WNT6
No disorders were found for WNT6 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for WNT6 Gene
Publications for WNT6 Gene
- WNT10A and WNT6, clustered in human chromosome 2q35 region with head- to-tail manner, are strongly co-expressed in SW480 cells. (PMID: 11350055) Kirikoshi H. … Katoh M. (Biochem. Biophys. Res. Commun. 2001) 2 3 4 22 64
- Partial cloning and assignment of WNT6 to human chromosome band 2q35 by in situ hybridization. (PMID: 10343101) Rankin J. … Lindsay S. (Cytogenet. Cell Genet. 1999) 2 3 4 64
- WNT6 is a novel target gene of caveolin-1 promoting chemoresistance to epirubicin in human gastric cancer cells. (PMID: 22370641) Yuan G. … Burgermeister E. (Oncogene 2013) 3 4 64
- Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. (PMID: 20634891) Jugessur A. … Murray J.C. (PLoS ONE 2010) 3 46 64
- Analysis of candidate genes on chromosome 2 in oral cleft case-parent trios from three populations. (PMID: 16953426) Beaty T.H. … Scott A.F. (Hum. Genet. 2006) 3 46 64
Products for WNT6 Gene
- R&D Systems Antibodies for WNT6 (Wnt-6)
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for WNT6
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for WNT6
- Search Origene for MassSpec and Protein Over-expression Lysates for WNT6
- Origene Custom Protein Services for WNT6
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for WNT6
- Browse OriGene Inhibitory RNA Products For WNT6
- OriGene qPCR primer pairs and template standards for WNT6
- OriGene qPCR primer pairs for WNT6
- OriGene CRISPR knockouts for WNT6
- OriGene ORF clones in human for WNT6
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For WNT6
- GenScript: Next-day shipping cDNA ORF clone for WNT6 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for WNT6
- GenScript Custom Assay Services for WNT6
- GenScript Custom overexpressing Cell Line Services for WNT6
- GenScript: Design CRISPR guide RNA sequences for WNT6
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for WNT6
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for WNT6
- Novus Biologicals proteins and lysates for WNT6
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Taconic Biosciences Mouse Models for WNT6
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for WNT6
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- antibodies-online Antibodies for WNT6: See all 62
- antibodies-online Kits for WNT6: See all 4
- antibodies-online Proteins for WNT6: See all 3
- Search antibodies-online for peptides
- GeneTex WNT6 antibody for WNT6
- Search GeneTex for Proteins for WNT6
- ViGene Biosciences adenoviral particle packaged cDNA for WNT6 gene
- ViGene Biosciences lentiviral particle packaged cDNA for WNT6 gene
- ViGene Biosciences ready-to-package AAV shRNAs for WNT6 gene
- Search ViGene Biosciences for WNT6
- Horizon Cell Lines for WNT6
- Cyagen custom Knockout/knockin (KOKI) mouse models for WNT6
- VectorBuilder custom plasmid, inducible vectors for WNT6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for WNT6
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for WNT6 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer