WISP3 Gene
protein-coding GIFtS: 53
GCID: GC06P112375
|
|
WNT1 inducible signaling pathway protein 3
| |
Aliases
for WISP3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| WNT1 Inducible Signaling Pathway Protein 31 2 | | PPAC2 5 | | CCN61 2 3 | | PPD2 5 | | WISP-32 3 | | LIBC2 | | CCN Family Member 62 3 | | WNT1-Inducible-Signaling Pathway Protein 32 |
Export aliases for WISP3 gene to outside databasesPrevious GC identifers: GC06P112210 GC06P112398 GC06P112420 GC06P112481 GC06P109950 |
Summaries
for WISP3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for WISP3:
This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to theconnective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signalingproteins that mediate diverse developmental processes. The CTGF family members are characterized by four conservedcysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondindomain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream inthe WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated withprogressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene isessential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encodingdifferent isoforms have been found for this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: WISP3_HUMAN, O95389Function: Appears to be required for normal postnatal skeletal growth and cartilage homeostasis
Gene Wiki entry for WISP3 (WNT1-inducible-signaling pathway protein 3)
|
Genomic Views
for WISP3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_025741.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the WISP3 gene promoter:
Pbx1a GCNF GCNF-1 SEF-1 (1) GCNF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for WISP3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WISP3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6q21 Ensembl cytogenetic band: 6q21 HGNC cytogenetic band: 6q21WISP3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P112375: view genomic region
(about GC identifiers)
Start:
|
112,375,275 bp from pter |
End:
|
112,392,171 bp from pter |
Size:
|
16,897 bases |
Orientation:
|
plus strand |
|
Proteins
for WISP3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: WISP3_HUMAN, O95389 (See
protein sequence)Recommended Name: WNT1-inducible-signaling pathway protein 3 precursor Size: 354 amino acids; 39293 Da
Subcellular location: Secreted (Probable)
Secondary accessions: Q3KR29 Q5H8W4 Q6UXH6Alternative splicing: 2 isoforms: O95389-1 O95389-2 Explore the universe of human proteins at neXtProt for WISP3: NX_O95389
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O95389
WISP3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_003871.1 NP_937882.1
ENSEMBL proteins: ENSP00000357655 ENSP00000395928 ENSP00000357653 ENSP00000357652 ENSP00000386467 ENSP00000354734 ENSP00000230529
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
WISP3 for ontologies About GeneDecksing
WISP3 Antibody Products:
Assay Products for WISP3: |
Protein
Domains /
Families
for WISP3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
WISP3 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry O95389ProtoNet protein and cluster: O95389 2 Blocks protein families: IPB006207 Cystine knot IPB006208 Cystine knot domain
UniProtKB/Swiss-Prot: WISP3_HUMAN, O95389Similarity: Belongs to the CCN familySimilarity: Contains 1 CTCK (C-terminal cystine knot-like) domainSimilarity: Contains 1 IGFBP N-terminal domainSimilarity: Contains 1 TSP type-1 domain |
Function
for WISP3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: WISP3_HUMAN, O95389Function: Appears to be required for normal postnatal skeletal growth and cartilage homeostasis Genatlas biochemistry entry for WISP3:WNT1 inducible signaling pathway protein 3,connective tissue growth factor family,CCN family(CTGF,IGFBP10,NOU)expressed in adult skeletal muscle,colon,ovary and fetal lung,overexpressed in colon tumors,involvedin cell growth and differentiation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WISP3 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WISP3 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector (see all 2): WISP3 (NM_003880) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for WISP3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WISP3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WISP3 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005520 | insulin-like growth factor binding |
IEA | -- | | GO:0008083 | growth factor activity |
IEA | -- |
WISP3 for ontologies About GeneDecksing
5 GenomeRNAi human phenotypes for WISP3:
Animal Models:
1 MGI mutant phenotype (inferred from 2 alleles ) (MGI details for Wisp3):
WISP3 for phenotypes About GeneDecksing
|
Pathways & Interactions
for WISP3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for WISP3
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
WISP3 for ontologies About GeneDecksing
|
Drugs & Compounds
for WISP3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
WISP3 for compounds About GeneDecksing
 Browse Tocris compounds for WISP3
3 Novoseek chemical compound relationships for WISP3 gene About this table
Search CenterWatch for drugs/clinical trials and news about WISP3
|
Transcripts
for WISP3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for WISP3 gene (3 alternative transcripts): NM_003880.3 NM_198239.1 NM_130396.1 Unigene Cluster for WISP3: WNT1 inducible signaling pathway protein 3 Hs.558428 [show with all ESTs]Unigene Representative Sequence: NM_1982398 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000368666(uc003pvo.3) ENST00000454589(uc003pvm.3 uc003pvn.3)
ENST00000483439 ENST00000368664 ENST00000368663 ENST00000409166 ENST00000361714
ENST00000230529
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WISP3 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WISP3 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): WISP3 (NM_003880) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for WISP3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WISP3 |
Additional cDNA sequence: AB075040.1 AF100781.1 AF143679.1 AY358350.1 BC035250.1 BC102031.1 BC105941.1 5 DOTS entries: DT.412752 DT.91828965 DT.75196414 DT.101981620 DT.40209954 24/30 AceView cDNA sequences (see all 30): AW614291 AW025138 AF100781 AB075040 AF143679 NM_198239 AY358350 AY358349 NM_003880 NM_130396 CD617639 CN480250 BC035250 BM715228 AI457678 BG290786 CD617637 CD617635 BC012028 BX281260 BI492770 AW592899 AI608669 AA592984
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for WISP3 (see all 7) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6 | ^ | 7 |
|---|
|
| SP1: | | | | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | | | - | | | | | | | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | | | | | | | - | | | | | | | | | | - | | | | |
| SP5: | | | | | | | | | | | | | - | | | | | | - | | - | | | | | | | | - | | | |
ECgene alternative splicing isoforms for WISP3
|
Expression
for WISP3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| WISP3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGGGATGGGA
About this image
See WISP3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for WISP3
SOURCE GeneReport for Unigene cluster: Hs.558428
UniProtKB/Swiss-Prot: WISP3_HUMAN, O95389Tissue specificity: Predominant expression in adult kidney and testis and fetal kidney. Weaker expression found inplacenta, ovary, prostate and small intestine. Also expressed in skeletally-derived cells such as synoviocytes andarticular cartilage chondrocytes
SABiosciences Custom PCR Arrays for WISP3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for WISP3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat WISP3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WISP3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WISP3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WISP3 |
Orthologs
for WISP3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for WISP3 gene from 4/11 species (see all 11) About this table
ENSEMBL Gene Tree for WISP3 (if available)
TreeFam Gene Tree for WISP3 (if available) |
Paralogs
for WISP3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for WISP3 gene
- WISP22 NOV2 CTGF2 CYR612 WISP12
6 SIMAP similar genes for WISP3 using alignment to 6 protein entries: WISP3_HUMAN (see all proteins):LIBC wisp3 varinat WISP1 CTGF NOV CYR61
WISP3 for paralogs About GeneDecksing
|
Genomic Variants
for WISP3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for WISP3 (112375275 - 112392171 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for WISP3: --
Human Gene Mutation Database (HGMD): WISP3
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing WISP3 |
|
Disorders
/ Diseases
for WISP3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
WISP3 for disorders About GeneDecksing
OMIM gene information: 603400
OMIM disorders: 208230
UniProtKB/Swiss-Prot: WISP3_HUMAN, O95389
Defects in WISP3 are the cause of progressive pseudorheumatoid arthropathy of childhood (PPAC) [MIM:208230].PPAC is an autosomal recessive disorder characterized by stiffness and swelling of joints, motor weakness and jointcontractures. Signs and symptoms of the disease develop typically between three and eight years of age. Thisprogressive disease is a primary disorder of articular cartilage with continued cartilage loss and destructive bonechanges with aging
19  diseases for WISP3: About MalaCardsspondyloepiphyseal dysplasia tarda spondyloepiphyseal dysplasia tarda with progressive arthropathy progressive pseudorheumatoid arthropathy of childhood spondyloepiphyseal dysplasia
arthropathy juvenile rheumatoid arthritis inflammatory breast cancer wilms tumor
rheumatoid arthritis breast cancer nephroblastoma arthritis
chondrosarcoma hepatocellular carcinoma colorectal cancer lung cancer
tuberculosis carcinoma prostatitis
3 diseases from the University of Copenhagen DISEASES database for WISP3:Arthropathy Juvenile rheumatoid arthritis Nephroblastoma 10/11 Novoseek disease relationships for WISP3 gene (see all 11) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| progressive pseudorheumatoid dysplasia |
98.7 |
27 |
17363178 (3), 16029628 (2), 17823661 (2), 17483925 (2) (see all 13) |
| inflammatory breast cancer |
91.1 |
15 |
10499627 (2), 14696649 (1), 18321996 (1), 16457688 (1) (see all 11) |
| wilms tumor |
57.1 |
5 |
15601861 (1), 15611078 (1), 14872491 (1), 15579080 (1) |
| arthropathy |
55 |
3 |
17942216 (1), 17363178 (1) |
| aggressiveness |
52.8 |
1 |
20372786 (1) |
| breast cancer |
42.5 |
12 |
17587813 (3), 20395207 (2), 17406949 (1), 18321996 (1) (see all 7) |
| progressive disease |
34.7 |
2 |
19401829 (1), 16480948 (1) |
| tumors |
31.6 |
13 |
14696649 (2), 15602803 (2), 20131997 (1), 15517620 (1) (see all 8) |
| arthritis |
16.6 |
2 |
15517620 (1), 16480948 (1) |
| metastasis |
12.5 |
2 |
18321996 (1), 20395207 (1) |
Human Genome Epidemiology (HuGE) Navigator: WISP3 (3 documents)
Export disorders for WISP3 gene to outside databases
|
Publications
for WISP3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for WISP3 gene, integrated from 9 sources (see all 68):
(articles sorted by number of sources associating them with WISP3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors. (PubMed id 9843955)1, 2, 3, 9 Pennica D.... Levine A.J. (1998)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- Mutations in the CCN gene family member WISP3 cause progressive pseudorheumatoid dysplasia. (PubMed id 10471507)1, 2 Hurvitz J.R.... Warman M.L. (1999)
- Inhibition of CCN6 (Wnt-1-induced signaling protein 3) down-regulates E-cadherin in the breast epithelium through induction of snail and ZEB1. (PubMed id 18321996)1, 9 Huang W....Kleer C.G. (2008)
- Wnt1 inducible signaling pathway protein-3 regulation and microsatellite structure in arthritis. (PubMed id 15517620)1, 9 Cheon H....Firestein G.S. (2004)
- Mutant WISP3 triggers the phenotype shift of articular chondrocytes by promoting sensitivity to IGF-1 hypothesis of spondyloepiphyseal dysplasia tarda with progressive arthropathy (SEDT-PA). (PubMed id 17363178)1, 9 Yang Y. and Liao E. (2007)
- Inhibition of CCN6 (WISP3) expression promotes neoplastic progression and enhances the effects of insulin-like growth factor-1 on breast epithelial cells. (PubMed id 16457688)1, 9 Zhang Y....Kleer C.G. (2005)
- Blockade of CCN6 (WISP3) activates growth factor-inde pendent survival and resistance to anoikis in human mammary epithelial cells. (PubMed id 20395207)1, 9 Huang W....Kleer C.G. (2010)
- WISP-3 functions as a ligand and promotes superoxide dismutase activity. (PubMed id 16480948)1, 9 Davis L....Sen M. (2006)
|
External Searches for WISP3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing WISP3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing WISP3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing WISP3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for WISP3 gene:
Search GeneIP for patents involving WISP3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for WISP3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for WISP3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for WISP3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for WISP3 | | | OriGene Protein Over-expression Lysate for WISP3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for WISP3 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WISP3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WISP3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for WISP3 | | OriGene Custom Protein Services for WISP3 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat WISP3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing WISP3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WISP3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat WISP3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WISP3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WISP3 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for WISP3 |
| |  |  |  |  | | | | |
 |
 |
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 | | | WISP3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WISP3 |
|  |  |  | | | | ThermoFisher Antibodies for WISP3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WISP3 |
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