WIPI2 Gene
protein-coding GIFtS: 52
GCID: GC07P005229
|
|
WD repeat domain, phosphoinositide interacting 2
| |
Aliases
for WIPI2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| WD Repeat Domain, Phosphoinositide Interacting 21 2 | | DKFZp686P021881 | | ATG18B1 2 | | FLJ129791 | | Atg211 2 | | FLJ142171 | | WIPI-22 3 | | FLJ429841 | | WIPI49-Like Protein 22 3 | | WD Repeat Domain Phosphoinositide-Interacting Protein 22 | | CGI-501 | | WD40 Repeat Protein Interacting With Phosphoinositides 22 | | DKFZP434J1541 | | |
Export aliases for WIPI2 gene to outside databasesPrevious GC identifers: GC07P005006 GC07P005196 GC07P005144 |
Summaries
for WIPI2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for WIPI2:
WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly ofmultiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-proteininteractions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propellerstructure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 (PubMed15602573)).(supplied by OMIM, Mar 2008)
UniProtKB/Swiss-Prot: WIPI2_HUMAN, Q9Y4P8Function: Probable early component of the autophagy machinery being involved in formation of preautophagosomalstructures and their maturation into mature phagosomes in response to PtdIns3P. May bind PtdIns3P
Gene Wiki entry for WIPI2
|
Genomic Views
for WIPI2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007819.17 NT_079592.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the WIPI2 gene promoter:
FAC1 Sp1 p53 GCNF GCNF-1 Nkx2-5 GCNF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for WIPI2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WIPI2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7p22.1 Ensembl cytogenetic band: 7p22.1 HGNC cytogenetic band: 7p22.1WIPI2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P005229: view genomic region
(about GC identifiers)
Start:
|
5,229,819 bp from pter |
End:
|
5,273,486 bp from pter |
Size:
|
43,668 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 5,276,190-5,319,841 |
|
Proteins
for WIPI2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: WIPI2_HUMAN, Q9Y4P8 (See
protein sequence)Recommended Name: WD repeat domain phosphoinositide-interacting protein 2 Size: 454 amino acids; 49408 Da
Subunit: Interacts with TECPR1
Subcellular location: Preautophagosomal structure membrane; Peripheral membrane protein; Cytoplasmic side.Note=Enriched at preautophagosomal structure membranes in response to ptdIns3P
Secondary accessions: B3KNC2 Q5MNZ8 Q6FI96 Q75L50 Q96IE4 Q9Y364Alternative splicing: 6 isoforms: Q9Y4P8-1 Q9Y4P8-2 Q9Y4P8-3 Q9Y4P8-4 Q9Y4P8-5 Q9Y4P8-6 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for WIPI2: NX_Q9Y4P8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y4P8
WIPI2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (5 alternative transcripts):
NP_001028690.1 NP_001028691.1 NP_001028692.1 NP_056425.1 NP_057087.2
ENSEMBL proteins: ENSP00000288828 ENSP00000384945 ENSP00000385297 ENSP00000371821 ENSP00000429654
Human Recombinant Protein Products:
Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8): About this table
WIPI2 for ontologies About GeneDecksing
WIPI2 Antibody Products:
Assay Products for WIPI2: |
Protein
Domains /
Families
for WIPI2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
WIPI2 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y4P8ProtoNet protein and cluster: Q9Y4P8 UniProtKB/Swiss-Prot: WIPI2_HUMAN, Q9Y4P8Similarity: Belongs to the WD repeat SVP1 familySimilarity: Contains 3 WD repeats |
Function
for WIPI2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: WIPI2_HUMAN, Q9Y4P8Function: Probable early component of the autophagy machinery being involved in formation of preautophagosomalstructures and their maturation into mature phagosomes in response to PtdIns3P. May bind PtdIns3P
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WIPI2 (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WIPI2 (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 5): WIPI2 (NM_016003) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for WIPI2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WIPI2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WIPI2 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
IPI | -- | | GO:0032266 | phosphatidylinositol-3-phosphate binding |
IDA | -- | | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding |
IDA | -- |
WIPI2 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for WIPI2:
|
Pathways & Interactions
for WIPI2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Apoptosis and Autophagy | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Cell Signaling Technology (CST) Pathway for WIPI2
WIPI2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for WIPI2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/583 Interacting proteins for WIPI2 (Q9Y4P82, 3 ENSP000002888284) via UniProtKB, MINT, STRING, and/or I2D (see all 583)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000045 | autophagic vacuole assembly |
IMP | -- | | GO:0000046 | NOT autophagic vacuole fusion |
IMP | -- |
WIPI2 for ontologies About GeneDecksing
|
Drugs & Compounds
for WIPI2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for WIPI2
Search CenterWatch for drugs/clinical trials and news about WIPI2
|
Transcripts
for WIPI2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for WIPI2 gene (5 alternative transcripts): NM_001033518.1 NM_001033519.1 NM_001033520.1 NM_015610.3 NM_016003.3 Unigene Cluster for WIPI2: WD repeat domain, phosphoinositide interacting 2 Hs.122363 [show with all ESTs]Unigene Representative Sequence: NM_01561014 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000288828(uc003snv.3 uc003snw.3 uc003snx.3 uc003sny.3 uc010ksv.3 uc003soa.3)
ENST00000401525 ENST00000404704 ENST00000466014 ENST00000485854 ENST00000382384
ENST00000496867 ENST00000475309(uc003snz.3) ENST00000484262 ENST00000465102
ENST00000480238 ENST00000488359 ENST00000471851 ENST00000479690
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WIPI2 (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WIPI2 (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 5): WIPI2 (NM_016003) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for WIPI2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WIPI2 |
Additional cDNA sequence: AF151808.1 AK023041.1 AK024279.1 AK124974.1 AK125007.1 AK315468.1 AL080155.1 AY691425.1 AY691426.1 BC004116.2 BC007596.1 BC021012.1 BC021068.1 BC021200.2 BX537624.1 CR533530.1 24/27 DOTS entries (see all 27): DT.75122586 DT.91874825 DT.91757688 DT.100819593 DT.95267440 DT.100669928 DT.443083 DT.40121362 DT.97795995 DT.100819587 DT.95267443 DT.100819597 DT.100819601 DT.100819585 DT.100819592 DT.100039964 DT.100639112 DT.100819589 DT.121121186 DT.121121200 DT.91757670 DT.91757689 DT.95267445 DT.95330684 24/567 AceView cDNA sequences (see all 567): BM565550 AI298007 BM976086 AI074158 BM792801 AA553845 CR624233 BG231989 CA433701 Z41442 BU622686 AA350352 BM909950 CR621388 BC004116 BG236099 BM908458 BQ027439 CB321917 BQ952965 CR615883 AI919054 T85751 AI992239
GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for WIPI2 (see all 10) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14a | · | 14b | · | 14c | ^ | 15a | · | 15b |
|---|
|
| SP1: | | | - | | | | | | - | | - | | | | | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | |
| SP2: | | | - | | - | | | | - | | - | | | | | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | |
| SP3: | | | - | | - | | | | - | | - | | | | | | | | | | | | | | | | - | | | | | | - | | | | - | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | | | - | | | | | | |
| SP5: | | | - | | | | | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for WIPI2
|
Expression
for WIPI2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| WIPI2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATTCTTCGGA
About this image
See WIPI2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for WIPI2
SOURCE GeneReport for Unigene cluster: Hs.122363
UniProtKB/Swiss-Prot: WIPI2_HUMAN, Q9Y4P8Tissue specificity: Ubiquitously expressed (at protein level). Highly expressed in heart, skeletal muscle and pancreas.Expression is down-regulated in pancreatic and in kidney tumors
SABiosciences Custom PCR Arrays for WIPI2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for WIPI2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat WIPI2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WIPI2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WIPI2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WIPI2 |
Orthologs
for WIPI2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for WIPI2 gene from 9/35 species (see all 35) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
WIPI21 |
WD repeat domain, phosphoinositide interacting 2 |
81.65(n)
94.95(a) |
|
416481 NM_001006162.1 NP_001006162.1 |
lizard
(Anolis carolinensis) |
Reptilia |
WIPI26 |
-- |
92(a) |
1 ↔ 1 |
GL343591.1(289755-312035) |
African clawed frog
(Xenopus laevis) |
Amphibia |
MGC532202 |
hypothetical protein MGC53220 |
79.44(n) |
|
BC046705.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wipi26 |
WD repeat domain, phosphoinositide interacting 2 |
87(a) |
1 ↔ 1 |
3(40815404-40832107) |
fruit fly
(Drosophila melanogaster) |
Insecta |
Atg181 |
Autophagy-specific gene 18 |
62.15(n)
63.69(a) |
|
38913 NM_206301.2 NP_996023.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
atg-181 |
Protein ATG-18 |
50.23(n)
42.66(a) |
|
179246 NM_171491.2 NP_741576.1 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
ATG18(YFR021W)4
ATG181 |
Phosphoinositide binding protein required for vesicle more4
Atg18p1 |
45.87(n)1
38.03(a)1 |
|
6(194812-196314)4
8505771, 4 NP_444297.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
ATG18B6 |
autophagy-related protein 18b |
28(a) |
1 → many |
4(14905137-14907592) |
rice
(Oryza sativa) |
Liliopsida |
-- |
atATG18b, putative, expressed |
26(a) |
1 → many |
2(33623458-33627745) |
ENSEMBL Gene Tree for WIPI2 (if available)
TreeFam Gene Tree for WIPI2 (if available) |
Paralogs
for WIPI2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for WIPI2 gene
- WIPI12 WDR45B2 WDR452
1 SIMAP similar gene for WIPI2 using alignment to 2 protein entries: WIPI2_HUMAN (see all proteins):WIPI1
WIPI2 for paralogs About GeneDecksing
3 Pseudogenes.org Pseudogenes for WIPI2
PGOHUM00000248875 PGOHUM00000237178 PGOHUM00000234858
|
Genomic Variants
for WIPI2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for WIPI2 (5229819 - 5273486 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for WIPI2
1 CNV: 99853 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing WIPI2 |
|
Disorders
/ Diseases
for WIPI2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
WIPI2 for disorders About GeneDecksing
OMIM gene information: 609225
OMIM disorders: --
2  diseases for WIPI2: About MalaCardspancreatitis malaria
Export disorders for WIPI2 gene to outside databases
|
Publications
for WIPI2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for WIPI2 gene, integrated from 9 sources (see all 25):
(articles sorted by number of sources associating them with WIPI2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy. (PubMed id 15602573)1, 2, 3 Proikas-Cezanne T....Nordheim A. (2004)
- Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation. (PubMed id 20505359)1, 2 Polson H.E.... Tooze S.A. (2010)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
- Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2 Lai C.H....Lin W. (2000)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- A Tecpr1-dependent selective autophagy pathway targets bacterial pathogens. (PubMed id 21575909)2 Ogawa M....Sasakawa C. (2011)
|
External Searches for WIPI2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing WIPI2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing WIPI2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing WIPI2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for WIPI2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for WIPI2 gene:
Search GeneIP for patents involving WIPI2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for WIPI2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for WIPI2 | | OriGene shRNA RFP for WIPI2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for WIPI2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for WIPI2 | | | OriGene Protein Over-expression Lysate for WIPI2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for WIPI2 | | OriGene 3'-UTR Clone for WIPI2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WIPI2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WIPI2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for WIPI2 | | OriGene Custom Protein Services for WIPI2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat WIPI2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing WIPI2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WIPI2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat WIPI2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WIPI2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WIPI2 |
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| | Antibodies & Assays for WIPI2 |
| | | | Search Tocris compounds for WIPI2 |
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 | | | WIPI2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WIPI2 |
|  |  |  | | | | Search ThermoFisher Antibodies for WIPI2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WIPI2 |
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