Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



WIPF3 Gene

protein-coding   GIFtS: 44
GCID: GC07P029842

WAS/WASL Interacting Protein Family, Member 3

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
WAS/WASL Interacting Protein Family, Member 31 2
CR162 3 5
Corticosteroids And Regional Expression Protein 16 Homolog2 3
WAS/WASL-Interacting Protein Family Member 32

External Ids:    HGNC: 220041   Entrez Gene: 6441502   Ensembl: ENSG000001225747   OMIM: 6124325   UniProtKB: A6NGB93   

Export aliases for WIPF3 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for WIPF3 Gene:
WIPF3 (WAS/WASL interacting protein family, member 3) is a protein-coding gene. GO annotations related to this gene include actin binding.

UniProtKB/Swiss-Prot: WIPF3_HUMAN, A6NGB9
Function: May be a regulator of cytoskeletal organization. May have a role in spermatogenesis (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000007.13  NT_007819.18  NC_018918.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the WIPF3 gene promoter:
         NF-1   Egr-1   RREB-1   POU3F1   Olf-1   C/EBPalpha   MZF-1   Nkx6-1   HOXA5   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for WIPF3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat WIPF3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p14.3   Ensembl cytogenetic band:  7p14.3   HGNC cytogenetic band: 7p15.1

WIPF3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WIPF3 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P029842:  view genomic region     (about GC identifiers)

Start:
29,846,102 bp from pter      End:
29,956,682 bp from pter
Size:
110,581 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 29,896,075-30,006,505     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: WIPF3_HUMAN, A6NGB9 (See protein sequence)
Recommended Name: WAS/WASL-interacting protein family member 3  
Size: 483 amino acids; 49458 Da
Subunit: Interacts with WASL, and monomeric and filamentous actin (By similarity)
Secondary accessions: B8ZZV2

Explore the universe of human proteins at neXtProt for WIPF3: NX_A6NGB9

Explore proteomics data for WIPF3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See WIPF3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001073998.2  
    ENSEMBL proteins: 
     ENSP00000386790   ENSP00000386878   ENSP00000242140  
    Reactome Protein details: A6NGB9

    WIPF3 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for WIPF3
    OriGene Protein Over-expression Lysate for WIPF3
    OriGene Custom MassSpec
    OriGene Custom Protein Services for WIPF3
    GenScript Custom Purified and Recombinant Proteins Services for WIPF3
    Novus Biologicals WIPF3 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for WIPF3

     
    Search eBioscience for Proteins for WIPF3 

     
    antibodies-online proteins for WIPF3 (2 products) 

     
    Search antibodies-online for peptides for WIPF3

    WIPF3 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for WIPF3
    Novus Biologicals WIPF3 Antibodies
    Search for Antibodies for WIPF3 at Abcam
    Cloud-Clone Corp. Antibodies for WIPF3
    ThermoFisher Antibodies for WIPF3
    Search antibodies-online for antibodies for WIPF3 

    WIPF3 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for WIPF3
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for WIPF3
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for WIPF3
    Cloud-Clone Corp. CLIAs for WIPF3
    Search eBioscience for ELISAs for WIPF3 
    antibodies-online kits for WIPF3 (6 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR003124 WH2_dom

    Graphical View of Domain Structure for InterPro Entry A6NGB9

    ProtoNet protein and cluster: A6NGB9

    UniProtKB/Swiss-Prot: WIPF3_HUMAN, A6NGB9
    Domain: The WH2 domain is found in a number of putative actin-binding proteins (By similarity)
    Domain: The profilin-binding motif has been implicated in the interaction with profilin and SH3 domains (By
    similarity)
    Domain: The KLKR motif is essential for G-actin binding and for actin polymerization (By similarity)
    Similarity: Belongs to the verprolin family
    Similarity: Contains 1 WH2 domain


    Find genes that share domains with WIPF3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: WIPF3_HUMAN, A6NGB9
    Function: May be a regulator of cytoskeletal organization. May have a role in spermatogenesis (By similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding IEA--
    GO:0017124SH3 domain binding IEA--
         
    Find genes that share ontologies with WIPF3           About GenesLikeMe


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Wipf3):
     homeostasis/metabolism  reproductive system 

    Find genes that share phenotypes with WIPF3           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Wipf3tm1Tta for WIPF3

       genOway: Develop your customized and physiologically relevant rodent model for WIPF3

    miRNA
    Products:
        
    miRTarBase miRNAs that target WIPF3:
    hsa-mir-744-5p (MIRT037538)

    Block miRNA regulation of human, mouse, rat WIPF3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate WIPF3 (see all 55):
    hsa-miR-3607-3p hsa-miR-3194-5p hsa-miR-30d hsa-miR-3653 hsa-miR-3921 hsa-miR-30a hsa-miR-124 hsa-miR-629*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for WIPF3
    Predesigned siRNA for gene silencing in human, mouse, rat WIPF3

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for WIPF3

    Clone
    Products:
         
    OriGene clones in human, mouse for WIPF3 (see all 6)
    OriGene ORF clones in mouse, rat for WIPF3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: WIPF3 (NM_001080529)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for WIPF3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WIPF3

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for WIPF3
    Browse ESI BIO Cell Lines and PureStem Progenitors for WIPF3 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WIPF3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    WIPF3_HUMAN, A6NGB9: Cytoplasm. Note=In hippocampal neurons colocalizes with WASL in the cell body, axons and the
    growth cone (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol4
    nucleus4
    cytoskeleton2
    endoplasmic reticulum1
    extracellular1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus ----
    GO:0005737cytoplasm ----
    GO:0005829cytosol TAS--

    Find genes that share ontologies with WIPF3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for WIPF3 About    
    See pathways by source

    SuperPathContained pathways About
    1Fcgamma receptor (FCGR) dependent phagocytosis
    Regulation of actin dynamics for phagocytic cup formation0.77
    Fcgamma receptor (FCGR) dependent phagocytosis0.77


    Find genes that share SuperPaths with WIPF3           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for WIPF3
        Regulation of actin dynamics for phagocytic cup formation


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for WIPF3
    Interactions:

        GeneGlobe Interaction Network for WIPF3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for WIPF3 (ENSP000003868784) via UniProtKB, MINT, STRING, and/or I2D (see all 68)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DNMBPENSP000003156594STRING: ENSP00000315659
    VSTM2LENSP000003625604STRING: ENSP00000362560
    GRB2ENSP000003390074STRING: ENSP00000339007
    MYO1FENSP000003448714STRING: ENSP00000344871
    ATP6V1AENSP000002733984STRING: ENSP00000273398
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007275multicellular organismal development IEA--
    GO:0007283spermatogenesis IEA--
    GO:0030154cell differentiation IEA--
    GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis TAS--
    GO:0045087innate immune response TAS--

    Find genes that share ontologies with WIPF3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for WIPF3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for WIPF3 gene: 
    NM_001080529.2  

    Unigene Cluster for WIPF3:

    WAS/WASL interacting protein family, member 3
    Hs.380698  [show with all ESTs]
    Unigene Representative Sequence: NM_001080529
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000409123(uc003taj.2) ENST00000409290(uc022aaz.1) ENST00000242140

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat WIPF3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate WIPF3 (see all 55):
    hsa-miR-3607-3p hsa-miR-3194-5p hsa-miR-30d hsa-miR-3653 hsa-miR-3921 hsa-miR-30a hsa-miR-124 hsa-miR-629*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for WIPF3
    Predesigned siRNA for gene silencing in human, mouse, rat WIPF3
    Clone
    Products:
         
    OriGene clones in human, mouse for WIPF3 (see all 6)
    OriGene ORF clones in mouse, rat for WIPF3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: WIPF3 (NM_001080529)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for WIPF3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WIPF3
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for WIPF3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat WIPF3
      QuantiTect SYBR Green Assays in human, mouse, rat WIPF3
      QuantiFast Probe-based Assays in human, mouse, rat WIPF3

    5 DOTS entries:

    DT.40191290  DT.310359  DT.99927508  DT.92416208  DT.309500 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    WIPF3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCAGGCAACT
    WIPF3 Expression
    About this image


    WIPF3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    WIPF3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    WIPF3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.380698
        Custom PCR Arrays for WIPF3
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for WIPF3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat WIPF3
    QuantiTect SYBR Green Assays in human, mouse, rat WIPF3
    QuantiFast Probe-based Assays in human, mouse, rat WIPF3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WIPF3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for WIPF3 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Wipf31 , 5 WAS/WASL interacting protein family, member 31, 5 81.24(n)1
    81.4(a)1
      6 (26.93 cM)5
    3303191  NM_001167860.11  NP_001161332.11 
     544296035 
    chicken
    (Gallus gallus)
    Aves WIPF36
    WAS/WASL interacting protein family, member 3
    48(a)
    1 ↔ 1
    2(34369172-34374862)
    lizard
    (Anolis carolinensis)
    Reptilia WIPF36
    WAS/WASL interacting protein family, member 3
    42(a)
    1 ↔ 1
    6(35556271-35600427)
    zebrafish
    (Danio rerio)
    Actinopterygii WIPF36
    WAS/WASL interacting protein family, member 3
    33(a)
    1 ↔ 1
    19(20157821-20166702) ENSDARG00000036245


    ENSEMBL Gene Tree for WIPF3 (if available)
    TreeFam Gene Tree for WIPF3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for WIPF3 (see all 2174)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs577577141,2
    C--29750341(+) TTTTT-/T/TTT 
            
    GAGAC
    1 -- int11NA 2
    rs1418128891,2
    --29844194(+) ACTGGC/GTCATG 1 -- us2k10--------
    rs1898792731,2
    --29844196(+) TGGCTC/TATGCT 1 -- us2k10--------
    rs1140745041,2
    C,F--29844212(+) TGCTCA/CGGAGA 1 -- us2k11Minor allele frequency- C:0.02WA 118
    rs1832130521,2
    --29844244(+) CCATGA/GCAATG 1 -- us2k10--------
    rs1879603941,2
    C--29844293(+) AGAATA/TCTAGT 1 -- us2k10--------
    rs1749091,2
    C,F,A,H--29844320(+) AGCTTG/TAGCAC 1 -- us2k125Minor allele frequency- T:0.21NS EA NA WA CSA 2331
    rs1151465581,2
    F--29844417(+) GGGCTT/AATGAA 1 -- us2k11Minor allele frequency- A:0.02WA 118
    rs1928738421,2
    C--29844475(+) ATTATA/GATTCT 1 -- us2k10--------
    rs1462456471,2
    C--29844556(+) CTACAC/TATAGA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for WIPF3 (29846102 - 29956682 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for WIPF3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2734192CNV Deletion23290073
    esv2734193CNV Deletion23290073
    esv2676972CNV Deletion23128226
    esv2734190CNV Deletion23290073
    esv2734191CNV Deletion23290073
    esv1527161CNV Deletion17803354
    nsv5682CNV Insertion18451855
    nsv887900CNV Loss21882294
    nsv830936CNV Gain17160897
    dgv2073e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing WIPF3
    DNA2.0 Custom Variant and Variant Library Synthesis for WIPF3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 612432    OMIM disorders: --


    Find genes that share disorders with WIPF3           About GenesLikeMe


    Export disorders for WIPF3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for WIPF3 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with WIPF3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (Nature 2003)
    2. The WH1 and EVH1 domains of WASP and Ena/VASP family members bind distinct sequence motifs. (PubMed id 12372256)1, 2 Zettl M. and Way M. (Curr. Biol. 2002)
    3. Genetic variants near PDGFRA are associated with corneal curvature in Australians. (PubMed id 22969067)1 Mishra A....Mackey D.A. (amp 2012)
    4. Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor. (PubMed id 21706016)1 Bisson N....Pawson T. (Nat. Biotechnol. 2011)
    5. [Expression of CR16 in the testis of patients with idiopathic azoospermia]. (PubMed id 21348202)1 Wen Z.N....Xiang W.P. (Zhonghua Nan Ke Xue 2010)
    6. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    7. Male-specific sterility caused by the loss of CR16. (PubMed id 17573773)1 Suetsugu S....Takenawa T. (amp 2007)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)
    9. Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton. (PubMed id 14506234)1 Salazar M.A.... De Camilli P. (J. Biol. Chem. 2003)
    10. CR16 forms a complex with N-WASP in brain and is a novel member of a conserved proline-rich actin-binding protein family. (PubMed id 11553796)1 Ho H.Y....Kirschner M.W. (Proc. Natl. Acad. Sci. U.S.A. 2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 644150 HGNC: 22004 Ensembl:ENSG00000122574 euGenes: HUgn644150 ECgene: WIPF3
    H-InvDB: WIPF3

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for WIPF3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for WIPF3 gene:
    Search GeneIP for patents involving WIPF3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for WIPF3  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for WIPF3  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for WIPF3  
     OriGene qSTAR qPCR primer pairs in human, mouse for WIPF3   OriGene Purified Protein for WIPF3  
     OriGene ORF clones in mouse, rat for WIPF3   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for WIPF3   OriGene Custom Protein Services for WIPF3  

     
     
     Block miRNA regulation of human, mouse, rat WIPF3 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing WIPF3
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat WIPF3 Predesigned siRNA for gene silencing in human, mouse, rat WIPF3
     QuantiFast Probe-based Assays in human, mouse, rat WIPF3 QuantiTect SYBR Green Assays in human, mouse, rat WIPF3
     Custom PCR Arrays for WIPF3 Search Chromatin IP Primers for WIPF3
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat WIPF3  GeneGlobe Interaction Network for WIPF3
     Regulatory tfbs in WIPF3 promoter
     GenScript Custom Purified and Recombinant Proteins Services for WIPF3 GenScript cDNA clones with any tag delivered in your preferred vector for WIPF3
     GenScript Custom Assay Services for WIPF3 GenScript Custom overexpressing Cell Line Services for WIPF3
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for WIPF3
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     WIPF3 antibodies
     WIPF3 lysates
     Search for Antibodies for WIPF3 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for WIPF3
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for WIPF3
     Antibodies for WIPF3
     ELISAs for WIPF3
     CLIAs for WIPF3



     Browse ESI BIO Cell Lines and PureStem Progenitors for WIPF3
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WIPF3
     Browse SwitchGear 3'UTR luciferase reporter plasmids for WIPF3
     Browse SwitchGear Promoter luciferase reporter plasmids for WIPF3
     ThermoFisher Antibodies for WIPF3
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WIPF3
     Browse compounds at ApexBio
     Search Addgene for plasmids for WIPF3
      Search eBioscience for proteins for WIPF3
      Search eBioscience for elisas for WIPF3
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for WIPF3
      Search antibodies-online for antibodies for WIPF3
     antibodies-online kits for WIPF3 (6 products)
      Search antibodies-online for peptides for WIPF3
     antibodies-online proteins for WIPF3 (2 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      WIPF3 gene at Home site.
    Version: 3.12.252 27 Nov 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4