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WFIKKN1 Gene

protein-coding   GIFtS: 48
GCID: GC16P000689

WAP, Follistatin/Kazal, Immunoglobulin, Kunitz And Netrin...

(Previous name: chromosome 16 open reading frame 12)
(Previous symbol: C16orf12)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
WAP, Follistatin/Kazal, Immunoglobulin, Kunitz And Netrin Domain
Containing 11 2
     hGASP-22 3
C16orf121 2 3     Chromosome 16 Open Reading Frame 121
WFIKKN2 3 5     RJD22
WAP Four-Disulfide Core Domain 20A1 2     WFDC20A2
Growth And Differentiation Factor-Associated Serum Protein 22 3     WAP, FS, Ig, KU, And NTR-Containing Protein2
WAP, Follistatin, Immunoglobulin, Kunitz And NTR Domain-Containing Protein2 3     WAP, Kazal, Immunoglobulin, Kunitz And NTR Domain-Containing Protein 12
GASP-22 3     GASP23

External Ids:    HGNC: 309121   Entrez Gene: 1171662   Ensembl: ENSG000001275787   OMIM: 6080215   UniProtKB: Q96NZ83   

Export aliases for WFIKKN1 gene to outside databases

Previous GC identifers: GC16P000622 GC16P000623 GC16P000680 GC16P000602 GC16P000681 GC16P000682 GC16P000683


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for WFIKKN1 Gene:
This gene encodes a secreted multidomain protein consisting of a signal peptide, a WAP domain, a follistatin
domain, an immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. These domains have been
implicated frequently in inhibition of various types of proteases, suggesting that the encoded protein may be a
multivalent protease inhibitor and may control the action of multiple types of serine proteases as well as
metalloproteinases. (provided by RefSeq, Jul 2008)

GeneCards Summary for WFIKKN1 Gene:
WFIKKN1 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1) is a protein-coding gene. GO annotations related to this gene include metalloendopeptidase inhibitor activity and serine-type endopeptidase inhibitor activity. An important paralog of this gene is WFIKKN2.

UniProtKB/Swiss-Prot: WFKN1_HUMAN, Q96NZ8
Function: Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine
protease- and metalloprotease-inhibitor activity (By similarity)

Gene Wiki entry for WFIKKN1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NC_018927.2  NT_010393.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the WFIKKN1 gene promoter:
         NF-1   NF-1/L   RP58   AP-2alpha isoform 3   AP-2alpha isoform 2   E47   HEN1   AP-2alpha isoform 4   AP-2alpha   AP-2alphaA   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for WFIKKN1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat WFIKKN1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13

WFIKKN1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WFIKKN1 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P000689:  view genomic region     (about GC identifiers)

Start:
679,239 bp from pter      End:
684,116 bp from pter
Size:
4,878 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: WFKN1_HUMAN, Q96NZ8 (See protein sequence)
Recommended Name: WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 precursor  
Size: 548 amino acids; 58798 Da
Sequence caution: Sequence=AAK61237.1; Type=Erroneous gene model prediction; Sequence=BAC11566.1; Type=Frameshift;
Positions=147;
2 PDB 3D structures from and Proteopedia for WFIKKN1:
2DDI (3D)        2DDJ (3D)    
Secondary accessions: Q7LDW0 Q8NBQ1 Q96S20

Explore the universe of human proteins at neXtProt for WFIKKN1: NX_Q96NZ8

Explore proteomics data for WFIKKN1 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn493

  • See WFIKKN1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_444514.1  
    ENSEMBL proteins: 
     ENSP00000324763  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ISET: Immunoglobulin superfamily / I-set domain containing
    WFDC: WAP four-disulfide core domain containing

    Selected InterPro protein domains (see all 11):
     IPR003598 Ig_sub2
     IPR008993 TIMP-like_OB-fold
     IPR002350 Kazal_dom
     IPR013098 Ig_I-set
     IPR002223 Prot_inh_Kunz-m

    Graphical View of Domain Structure for InterPro Entry Q96NZ8

    ProtoNet protein and cluster: Q96NZ8

    4 Blocks protein domains:
    IPB003598 Immunoglobulin C-2 type
    IPB008197 4-disulphide core signature
    IPB011497 Protease inhibitor
    IPB013098 Immunoglobulin I-set


    UniProtKB/Swiss-Prot: WFKN1_HUMAN, Q96NZ8
    Domain: The second BPTI/Kunitz inhibitor domain is able to inhibit trypsin. It has however no activity toward
    chymotrypsin, elastase, plasmin, pancreatic kallikrein, lung tryptase, plasma kallikrein, thrombin, urokinase or
    tissue plasminogen activator
    Similarity: Belongs to the WFIKKN family
    Similarity: Contains 2 BPTI/Kunitz inhibitor domains
    Similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain
    Similarity: Contains 1 Kazal-like domain
    Similarity: Contains 1 NTR domain
    Similarity: Contains 1 WAP domain


    Find genes that share domains with WFIKKN1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: WFKN1_HUMAN, Q96NZ8
    Function: Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine
    protease- and metalloprotease-inhibitor activity (By similarity)

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004867serine-type endopeptidase inhibitor activity IEA--
    GO:0005515protein binding IPI--
    GO:0008191metalloendopeptidase inhibitor activity IEA--
    GO:0030414peptidase inhibitor activity ----
         
    Find genes that share ontologies with WFIKKN1           About GenesLikeMe


    Phenotypes:
         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Wfikkn1):
     craniofacial  digestive/alimentary  muscle  skeleton 

    Find genes that share phenotypes with WFIKKN1           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Wfikkn1tm1.1Sjl for WFIKKN1

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for WFIKKN1
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    miRTarBase miRNAs that target WFIKKN1:
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    WFKN1_HUMAN, Q96NZ8: Secreted (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular3
    cytosol1
    lysosome1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    Find genes that share ontologies with WFIKKN1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for WFIKKN1
    Interactions:

        Search GeneGlobe Interaction Network for WFIKKN1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    Selected Interacting proteins for WFIKKN1 (Q96NZ81, 2, 3 ENSP000003247634) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CSNK2BP678702, 3MINT-8253814 I2D: score=2 
    ENSG00000206406P678702, 3MINT-8253814 I2D: score=2 
    ENSG00000224398P678702, 3MINT-8253814 I2D: score=2 
    ENSG00000224774P678702, 3MINT-8253814 I2D: score=2 
    ENSG00000228875P678702, 3MINT-8253814 I2D: score=2 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for WFIKKN1 (WFKN1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for WFIKKN1 gene: 
    NM_053284.2  

    Unigene Cluster for WFIKKN1:

    WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
    Hs.345818  [show with all ESTs]
    Unigene Representative Sequence: AK075356
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000573440(uc002chs.1) ENST00000319070(uc002cht.1)
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      QuantiFast Probe-based Assays in human, mouse, rat WFIKKN1

    Additional mRNA sequence: 

    AF422194.1 AK075356.1 AK314757.1 BC101602.1 BC101606.1 

    2 DOTS entries:

    DT.102842640  DT.97765902 

    Selected AceView cDNA sequences (see all 243):

    BF116146 AK075356 BQ027275 BE621282 BF813406 AA514649 AI819096 AI307130 
    BC001581 BU619004 AI631038 AW166046 BQ287791 AI660444 BM666257 BU527649 
    AW005486 AI769701 BF593711 BM055198 CD674470 AI937817 BM052895 BE217726 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    WFIKKN1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGTGAGGTGC
    WFIKKN1 Expression
    About this image


    WFIKKN1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Muscle Progenitor Cells Mandibular Arch Muscles
    WFIKKN1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    WFIKKN1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.345818

    UniProtKB/Swiss-Prot: WFKN1_HUMAN, Q96NZ8
    Tissue specificity: Expressed in pancreas, kidney, liver, placenta, and lung

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for WFIKKN1 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Wfikkn11 , 5 WAP, FS, Ig, KU, and NTR-containing protein 11, 5 82.52(n)1
    88.53(a)1
      17 (12.97 cM)5
    2150011  NM_001100454.11  NP_001093924.11 
     258776305 
    chicken
    (Gallus gallus)
    Aves WFIKKN11 WAP, follistatin/kazal, immunoglobulin, kunitz and more 76.89(n)
    69.9(a)
      429301  XM_426858.4  XP_426858.2 
    lizard
    (Anolis carolinensis)
    Reptilia WFIKKN16
    WAP, follistatin/kazal, immunoglobulin, kunitz and...
    68(a)
    1 ↔ 1
    AAWZ02036908(773-8147)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia wfikkn11 WAP, follistatin/kazal, immunoglobulin, kunitz and more 60.67(n)
    59.88(a)
      100490754  XM_002932449.2  XP_002932495.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wfikkn11 WAP, follistatin/kazal, immunoglobulin, kunitz and more 64.44(n)
    55.15(a)
      406570  NM_214747.1  NP_999912.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F22E12.16
    ZK287.46
    (see all 4)
    Protein F22E12.1 (F22E12.1) mRNA, complete cds
    Protein ZK287.4, isoform c (ZK287.4) mRNA, complet...
    (see all 4)
    8(a)
    7(a)
    (see all 4)
    many ↔ many
    many ↔ many
    (see all 4)
    V(10453866-10457347) WBGene00009058
    V(9680375-9685659) WBGene00013965


    ENSEMBL Gene Tree for WFIKKN1 (if available)
    TreeFam Gene Tree for WFIKKN1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for WFIKKN1 gene
    WFIKKN22  AMBP2  SPINT32  TFPI22  TFPI2  
    1 SIMAP similar gene for WFIKKN1 using alignment to 1 protein entry:     WFKN1_HUMAN:
    WFIKKN2

    Find genes that share paralogs with WFIKKN1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for WFIKKN1 (see all 186)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs124478741,2
    C,H--679814(+) CCTCCC/TTGGCA 1 -- us2k117Minor allele frequency- T:0.00NS EA NA WA CSA 794
    rs1477789081,2
    --679928(+) GAGCCA/GTCTCC 1 -- us2k10--------
    rs171393761,2
    C,F,H--679953(+) CCAGAC/TCAGGC 1 -- us2k123Minor allele frequency- T:0.17NA NS EA WA CSA 2259
    rs769993571,2
    C,F--679958(+) CCAGGC/GTCCTG 1 -- us2k11Minor allele frequency- G:0.01NA 120
    rs734854671,2
    C,F--680025(+) GGTCTC/TAAGAG 1 -- us2k12Minor allele frequency- T:0.06WA 120
    rs1488460941,2
    --680142(+) CCCCAA/GCGAAG 1 -- us2k10--------
    rs344218121,2
    C,F--680149(+) GAAGAG/AGAGCC 1 -- us2k16Minor allele frequency- A:0.05NA 308
    rs1502961781,2
    C--680174(+) GCCCC-/GCCG  
            
    GCCGA
    1 -- us2k10--------
    rs1834910551,2
    --680180(+) GCCGAC/TGGGGG 1 -- us2k10--------
    rs1425447941,2
    --680273(+) GCGGTA/GCCATC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for WFIKKN1 (679239 - 684116 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for WFIKKN1 (see all 24):    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv352e201CNV Deletion23290073
    esv2750214CNV Deletion23290073
    esv2750216CNV Deletion23290073
    esv2422427CNV Duplication17116639
    dgv2489n71CNV Loss21882294
    dgv2475n71CNV Loss21882294
    nsv904760CNV Loss21882294
    dgv334n27CNV Loss19166990
    nsv904779CNV Loss21882294
    nsv904707CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608021    OMIM disorders: --


    Find genes that share disorders with WFIKKN1           About GenesLikeMe


    Export disorders for WFIKKN1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for WFIKKN1 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with WFIKKN1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A human protein containing multiple types of protease-inhibitory modules. (PubMed id 11274388)1, 2, 3, 9 Trexler M.... Patthy L. (Proc. Natl. Acad. Sci. U.S.A. 2001)
    2. Distinct expression pattern of two related human proteins containing multiple types of protease-inhibitory modules. (PubMed id 11928817)1, 3, 9 Trexler M.... Patthy L. (Biol. Chem. 2002)
    3. Second Kunitz-type protease inhibitor domain of the human WFIKKN1 protein. (PubMed id 16791741)1, 2 Liepinsh E.... Otting G. (J. Biomol. NMR 2006)
    4. Expression, purification and characterization of the second Kunitz- type protease inhibitor domain of the human WFIKKN protein. (PubMed id 12709070)1, 2 Nagy A.... Patthy L. (Eur. J. Biochem. 2003)
    5. Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. (PubMed id 11157797)1, 2 Daniels R.J....Higgs D.R. (Hum. Mol. Genet. 2001)
    6. Both WFIKKN1 and WFIKKN2 have high affinity for growth and differentiation factors 8 and 11. (PubMed id 18596030)1, 9 KondA!s K....Patthy L. (J. Biol. Chem. 2008)
    7. Latent myostatin has significant activity and this activity is controlled more efficiently by WFIKKN1 than by WFIKKN2. (PubMed id 23829672)1 SzlA!ma G....Patthy L. (FEBS J. 2013)
    8. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
    9. WFIKKN1 and WFIKKN2 bind growth factors TGFI^1, BMP2 and BMP4 but do not inhibit their signalling activity. (PubMed id 21054789)1 SzlA!ma G....Patthy L. (FEBS J. 2010)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 117166 HGNC: 30912 AceView: RAB40CandWFIKKN1 Ensembl:ENSG00000127578 euGenes: HUgn117166
    ECgene: WFIKKN1 H-InvDB: WFIKKN1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for WFIKKN1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for WFIKKN1 gene:
    Search GeneIP for patents involving WFIKKN1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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