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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

WEE2 Gene

protein-coding   GIFtS: 45
GCID: GC07P141409

WEE1 Homolog 2 (S. Pombe)

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
WEE1 Homolog 2 (S. Pombe)1 2     EC 2.7.10.23 8
Wee1-Like Protein Kinase 1B2 3     Wee1-Like Protein Kinase 22
Wee1B Kinase2 3     EC 2.7.108
WEE1B2 3     

External Ids:    HGNC: 196841   Entrez Gene: 4945512   Ensembl: ENSG000002141027   OMIM: 6140845   UniProtKB: P0C1S83   

Export aliases for WEE2 gene to outside databases

Previous GC identifers: GC07U901539 GC07P141055 GC07P135704


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for WEE2 Gene: 
WEE2 (WEE1 homolog 2 (S. pombe)) is a protein-coding gene. Diseases associated with WEE2 include subacute thyroiditis, and thyroiditis, and among its related super-pathways are Cell cycle. GO annotations related to this gene include non-membrane spanning protein tyrosine kinase activity and protein serine/threonine kinase activity. An important paralog of this gene is PKMYT1.

UniProtKB/Swiss-Prot: WEE2_HUMAN, P0C1S8
Function: Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key
regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes
during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating
CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II
exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and
promote pronuclear formation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.2  NT_007914.15  NT_079596.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the WEE2 gene promoter:
         AML1a   GATA-3   Tal-1beta   HNF-1A   PPAR-alpha   POU2F1   POU2F1a   HNF-1   ITF-2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for WEE2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WEE2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q32   Ensembl cytogenetic band:  7q34   HGNC cytogenetic band: 7q32

WEE2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WEE2 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P141409:  view genomic region     (about GC identifiers)

Start:
141,408,153 bp from pter      End:
141,431,071 bp from pter
Size:
22,919 bases      Orientation:
plus strand

2 alternative locations:
Chr7+,CRA_TCAG 140,745,872-140,768,791      Chr7+,NW_003315922 80,953-103,871     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: WEE2_HUMAN, P0C1S8 (See protein sequence)
Recommended Name: Wee1-like protein kinase 2  
Size: 567 amino acids; 62925 Da
Subcellular location: Nucleus

Explore the universe of human proteins at neXtProt for WEE2: NX_P0C1S8

Explore proteomics data for WEE2 at MOPED 

Post-translational modifications:

  • UniProtKB: Phosphorylation leads to increase its activity (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P0C1S8

  • 3 DME Specific Peptides for WEE2 (P0C1S8)
     WAEDDHM  LGHHPHV  VEEGDSRFLANE 

    WEE2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    WEE2 Protein Expression
    REFSEQ proteins: NP_001099028.1  
    ENSEMBL proteins: 
     ENSP00000380675   ENSP00000420388  

    Human Recombinant Protein Products for WEE2: 
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for WEE2 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005813centrosome IDA--

    WEE2 for ontologies           About GeneDecksing



    WEE2 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    IUPHAR Guide to PHARMACOLOGY protein family classification: WEE1 homolog 2 (S. pombe) 
    WEE family

    5 InterPro protein domains:
     IPR017164 Wee1-like_protein_kinase
     IPR017441 Protein_kinase_ATP_BS
     IPR011009 Kinase-like_dom
     IPR008271 Ser/Thr_kinase_AS
     IPR000719 Prot_kinase_cat_dom

    Graphical View of Domain Structure for InterPro Entry P0C1S8

    ProtoNet protein and cluster: P0C1S8

    UniProtKB/Swiss-Prot: WEE2_HUMAN, P0C1S8
    Similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily
    Similarity: Contains 1 protein kinase domain


    WEE2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: WEE2_HUMAN, P0C1S8
    Function: Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key
    regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes
    during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating
    CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II
    exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and
    promote pronuclear formation (By similarity)
    Catalytic activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate

         Enzyme Numbers (IUBMB): EC 2.7.10.21 2 EC 2.7.102

         Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000287magnesium ion binding IEA--
    GO:0004672protein kinase activity ----
    GO:0004674protein serine/threonine kinase activity IEA--
    GO:0004713protein tyrosine kinase activity ----
    GO:0004715non-membrane spanning protein tyrosine kinase activity IEA--
         
    WEE2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for WEE2 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for WEE2 
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    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat WEE2
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate WEE2:
    hsa-miR-577 hsa-miR-3163 hsa-miR-548d-3p hsa-miR-551b*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Clone
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WEE2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for WEE2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Cell cycle
    Cell cycle0.59

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for WEE2):
        Cell cycle


    WEE2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for WEE2

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for WEE2 (ENSP000003806754) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCENSP000003672074STRING: ENSP00000367207
    About this table

    Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468protein phosphorylation ----
    GO:0007067mitosis IEA--
    GO:0007143female meiosis ISS--
    GO:0007343egg activation ----
    GO:0035038female pronucleus assembly ISS--

    WEE2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for WEE2

    Search CenterWatch for drugs/clinical trials and news about WEE2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for WEE2 gene: 
    NM_001105558.1  

    Unigene Cluster for WEE2:

    WEE1 homolog 2 (S. pombe)
    Hs.657927  [show with all ESTs]
    Unigene Representative Sequence: NM_001105558
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000397541(uc003vwn.2) ENST00000493845
    miRNA
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    4 QIAGEN miScript miRNA Assays for microRNAs that regulate WEE2:
    hsa-miR-577 hsa-miR-3163 hsa-miR-548d-3p hsa-miR-551b*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for WEE2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat WEE2
    Clone
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    Sirion Biotech Customized lentivirus for stable overexpression of WEE2 
                         Customized lentivirus expression plasmids for stable overexpression of WEE2 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WEE2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WEE2

    Additional mRNA sequence: AK131218.1 

    2 DOTS entries:

    DT.92064000  DT.40111195 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    WEE2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATCCAACCTG
    WEE2 Expression
    About this image


    See WEE2 Protein Expression from SPIRE MOPED and PaxDB
    SOURCE GeneReport for Unigene cluster: Hs.657927

    UniProtKB/Swiss-Prot: WEE2_HUMAN, P0C1S8
    Tissue specificity: Expressed in testis

        SABiosciences Custom PCR Arrays for WEE2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WEE2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for WEE2 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Wee21 , 5 WEE1 homolog 2 (S. pombe)1, 5 77.43(n)1
    69.16(a)1
      6 (18.82 cM)5
    3817591  NM_201370.21  NP_958758.21 
     404428635 
    chicken
    (Gallus gallus)
    Aves WEE21 WEE1 homolog 2 (S. pombe) 62.38(n)
    56.16(a)
      427918  XM_003640413.1  XP_003640461.1 
    lizard
    (Anolis carolinensis)
    Reptilia WEE26
    WEE1 homolog 2 (S. pombe)
    50(a)
    1 ↔ 1
    5(16166056-16184640)
    zebrafish
    (Danio rerio)
    Actinopterygii wee21 WEE1 homolog 2 (S. pombe) 58.17(n)
    54.55(a)
      327471  NM_001044902.1  NP_001038367.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta wee6
    wee
    29(a)
    1 → many
    2L(6911090-6914138)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SWE16
    Protein kinase that regulates the G2/M transition ...
    13(a)
    1 → many
    X(76803-79262)


    ENSEMBL Gene Tree for WEE2 (if available)
    TreeFam Gene Tree for WEE2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for WEE2 gene
    PKMYT12  WEE12  
    3 SIMAP similar genes for WEE2 using alignment to 2 protein entries:     WEE2_HUMAN (see all proteins):
    DKFZp686I18166    WEE1    DKFZp564L2416

    WEE2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for WEE2
    PGOHUM00000242209


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    8 SNPs in WEE2 are shown    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0413054
    A gastric adenocarcinoma sample4--see VAR_0413052 N K mis40--------
    VAR_0413064
    An ovarian mucinous carcinoma sample4--see VAR_0413062 R H mis40--------
    VAR_0413074
    ----see VAR_0413072 D E mis40--------
    VAR_0413084
    ----see VAR_0413082 Y D mis40--------
    VAR_0413044
    ----see VAR_0413042 K T mis40--------
    rs1834519411,2
    --144792923(+) CTCTCG/TCTCGC 1 -- ds50010--------
    rs1419136721,2
    ----144792927(+) CTCTCG/TCTCTC 1 -- ds50010--------
    rs1499374981,2
    ----144792907(+) CTCTCG/TCTCTC 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for WEE2 (141408153 - 141431071 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for WEE2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv34135CNV Loss18971310

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 614084    OMIM disorders: --

    3 diseases for WEE2:    About MalaCards
    subacute thyroiditis    thyroiditis    gastric cancer

    2 diseases from the University of Copenhagen DISEASES database for WEE2:
    Western equine encephalitis     Subacute thyroiditis

    WEE2 for disorders           About GeneDecksing


    Export disorders for WEE2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for WEE2 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with WEE2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    2. Identification and characterization of human Wee1B, a new member of the Wee1 family of Cdk-inhibitory kinases. (PubMed id 11029659)1, 2 Nakanishi M.... Sasaki M. (2000)
    3. Genetic variants associated with disordered eating. (PubMed id 23568457)1 Wade T.D....Martin N.G. (2013)
    4. Functional genomics identifies therapeutic targets for MYC-driven cancer. (PubMed id 22623531)1 Toyoshima M....Grandori C. (2012)
    5. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    6. Patterns of somatic mutation in human cancer genomes. (PubMed id 17344846)2 Greenman C.... Stratton M.R. (2007)
    7. Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H....Kim N.S. (2005)
    8. The DNA sequence of human chromosome 7. (PubMed id 12853948)2 Hillier L.W.... Wilson R.K. (2003)
    9. The sequence of the human genome. (PubMed id 11181995)1 Venter J.C.... Zhu X. (2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 494551 HGNC: 19684 Ensembl:ENSG00000214102 euGenes: HUgn494551 ECgene: WEE2 Kegg: 494551
    H-InvDB: WEE2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for WEE2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for WEE2 gene:
    Search GeneIP for patents involving WEE2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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