Free for academic non-profit institutions. Other users need a Commercial license

Aliases for WDR97 Gene

Aliases for WDR97 Gene

  • WD Repeat Domain 97 2 3 5
  • KIAA1875 2 3 4

External Ids for WDR97 Gene

Previous HGNC Symbols for WDR97 Gene

  • KIAA1875

Summaries for WDR97 Gene

Entrez Gene Summary for WDR97 Gene

  • The function and protein-coding potential of this gene is unknown. The exon combination is based on AB058778.1 for which two possible open reading frames can be predicted (with start codons at nucleotide 26 or 2614). The position of the first ORF stop codon is consistent with a prediction of nonsense-mediated decay. Given the observation of the first ORF and its length, a predicted translation of the second ORF is inconsistent with the translation leaky scanning theory. Therefore, this gene is represented as a non-protein-coding transcript. [provided by RefSeq, Oct 2008]

GeneCards Summary for WDR97 Gene

WDR97 (WD Repeat Domain 97) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR97 Gene

Genomics for WDR97 Gene

Regulatory Elements for WDR97 Gene

Enhancers for WDR97 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around WDR97 on UCSC Golden Path with GeneCards custom track

Promoters for WDR97 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around WDR97 on UCSC Golden Path with GeneCards custom track

Genomic Location for WDR97 Gene

Chromosome:
8
Start:
144,107,726 bp from pter
End:
144,118,315 bp from pter
Size:
10,590 bases
Orientation:
Plus strand

Genomic View for WDR97 Gene

Genes around WDR97 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
WDR97 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for WDR97 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WDR97 Gene

Proteins for WDR97 Gene

  • Protein details for WDR97 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NE52-WDR97_HUMAN
    Recommended name:
    WD repeat-containing protein 97
    Protein Accession:
    A6NE52
    Secondary Accessions:
    • Q96JF2

    Protein attributes for WDR97 Gene

    Size:
    1622 amino acids
    Molecular mass:
    180307 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB47504.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};

    Alternative splice isoforms for WDR97 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for WDR97 Gene

Proteomics data for WDR97 Gene at MOPED

Post-translational modifications for WDR97 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for WDR97 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for WDR97 Gene

Domains & Families for WDR97 Gene

Gene Families for WDR97 Gene

Protein Domains for WDR97 Gene

Suggested Antigen Peptide Sequences for WDR97 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NE52

UniProtKB/Swiss-Prot:

WDR97_HUMAN :
  • Contains 6 WD repeats.
Similarity:
  • Contains 6 WD repeats.
genes like me logo Genes that share domains with WDR97: view

Function for WDR97 Gene

Gene Ontology (GO) - Molecular Function for WDR97 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IEA --
genes like me logo Genes that share ontologies with WDR97: view
genes like me logo Genes that share phenotypes with WDR97: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for WDR97 Gene

Localization for WDR97 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for WDR97 Gene

Pathways & Interactions for WDR97 Gene

SuperPathways for WDR97 Gene

No Data Available

Interacting Proteins for WDR97 Gene

Selected Interacting proteins: A6NE52-WDR97_HUMAN for WDR97 Gene via I2D

Symbol External ID(s) Details
FBXW7

Gene Ontology (GO) - Biological Process for WDR97 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for WDR97 Gene

Drugs & Compounds for WDR97 Gene

No Compound Related Data Available

Transcripts for WDR97 Gene

mRNA/cDNA for WDR97 Gene

(2) REFSEQ mRNAs :
(9) Selected AceView cDNA sequences:
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for WDR97 Gene

No ASD Table

Relevant External Links for WDR97 Gene

GeneLoc Exon Structure for
WDR97
ECgene alternative splicing isoforms for
WDR97

Expression for WDR97 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for WDR97 Gene

Orthologs for WDR97 Gene

This gene was present in the common ancestor of chordates.

Orthologs for WDR97 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia KIAA1875 36
  • 65 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 36
  • 69 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia KIAA1875 36
  • 35 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 58 (a)
OneToMany
-- 36
  • 45 (a)
OneToMany
-- 36
  • 32 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia KIAA1875 36
  • 98 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia KIAA1875 36
  • 36 (a)
OneToOne
Species with no ortholog for WDR97:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for WDR97 Gene

ENSEMBL:
Gene Tree for WDR97 (if available)
TreeFam:
Gene Tree for WDR97 (if available)

Paralogs for WDR97 Gene

No data available for Paralogs for WDR97 Gene

Variants for WDR97 Gene

Sequence variations from dbSNP and Humsavar for WDR97 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs4977196 - 144,108,511(-) AAGCC(C/G)GACAG nc-transcript-variant
rs34324679 - 144,109,615(+) CTCCA(A/C)GTGCA nc-transcript-variant
rs13250446 - 144,109,944(+) TCTCG(A/G)AGGCG nc-transcript-variant
rs7829844 -- 144,116,774(+) TCTGG(A/C)AAAGA nc-transcript-variant
rs7836836 -- 144,113,921(+) GGAGG(C/T)GGGCT intron-variant

Variation tolerance for WDR97 Gene

Gene Damage Index Score: 5.26; 70.20% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for WDR97 Gene

Disorders for WDR97 Gene

Relevant External Links for WDR97

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
WDR97
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
WDR97

No disorders were found for WDR97 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for WDR97 Gene

Publications for WDR97 Gene

  1. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11347906) Nagase T. … Ohara O. (DNA Res. 2001) 2 3 4 67
  2. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for WDR97 Gene

Sources for WDR97 Gene

Content