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Aliases for WDR97 Gene

Aliases for WDR97 Gene

  • WD Repeat Domain 97 2 3 5
  • KIAA1875 2 3 4
  • WD Repeat-Containing Protein 97 3

External Ids for WDR97 Gene

Previous HGNC Symbols for WDR97 Gene

  • KIAA1875

Summaries for WDR97 Gene

Entrez Gene Summary for WDR97 Gene

  • The function and protein-coding potential of this gene is unknown. The exon combination is based on AB058778.1 for which two possible open reading frames can be predicted (with start codons at nucleotide 26 or 2614). The position of the first ORF stop codon is consistent with a prediction of nonsense-mediated decay. Given the observation of the first ORF and its length, a predicted translation of the second ORF is inconsistent with the translation leaky scanning theory. Therefore, this gene is represented as a non-protein-coding transcript. [provided by RefSeq, Oct 2008]

GeneCards Summary for WDR97 Gene

WDR97 (WD Repeat Domain 97) is a Protein Coding gene.

Additional gene information for WDR97 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR97 Gene

Genomics for WDR97 Gene

Regulatory Elements for WDR97 Gene

Enhancers for WDR97 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08H144073 1.6 FANTOM5 Ensembl ENCODE 32.1 -33.3 -33330 1.2 HDGF PKNOX1 ATF1 ARNT TCF12 ZNF766 ELK1 ATF7 ZNF491 ZNF592 WDR97 ZNF251 ENSG00000254533 TSSK5P SPATC1 ENSG00000255085 CYC1 MAF1 SHARPIN ZNF252P
GH08H144062 1.4 FANTOM5 ENCODE dbSUPER 34.9 -44.2 -44225 2.3 ELF3 CTCF TFAP4 ZNF792 SAP130 ARID4B MAX RAD21 YY1 HIC1 WDR97 ENSG00000255224 SPATC1 CYC1 MAF1 SHARPIN PARP10 PLEC OPLAH MIR6846
GH08H144077 1.4 ENCODE dbSUPER 33.3 -29.0 -28959 3.4 HDGF PKNOX1 FOXA2 ARNT ARID4B SIN3A DMAP1 ZBTB7B YY1 ZNF766 ZNF623 ZNF7 WDR97 ZNF16 EEF1D MAF1 ENSG00000255224 GPAA1 CPSF1 ZNF251
GH08H143968 1.6 Ensembl ENCODE dbSUPER 19.4 -133.5 -133487 11 HDGF FOXA2 ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 SLC30A9 PLEC ZNF623 ZNF7 ZNF251 LRRC14 ZNF16 CPSF1 GPAA1 WDR97 ZNF707
GH08H144059 1.3 ENCODE dbSUPER 22.9 -47.4 -47374 2.3 ARID4B SIN3A DMAP1 YY1 ZNF766 SP5 MXD4 REST ZNF592 KAT8 ZNF623 ZNF251 ZNF7 ZNF16 WDR97 LRRC14 ENSG00000255224 TMED10P1 ENSG00000254533 GPAA1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around WDR97 on UCSC Golden Path with GeneCards custom track

Genomic Locations for WDR97 Gene

Genomic Locations for WDR97 Gene
10,590 bases
Plus strand

Genomic View for WDR97 Gene

Genes around WDR97 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
WDR97 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for WDR97 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WDR97 Gene

Proteins for WDR97 Gene

  • Protein details for WDR97 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    WD repeat-containing protein 97
    Protein Accession:
    Secondary Accessions:
    • Q96JF2

    Protein attributes for WDR97 Gene

    1622 amino acids
    Molecular mass:
    180307 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB47504.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};

    Alternative splice isoforms for WDR97 Gene


neXtProt entry for WDR97 Gene

Post-translational modifications for WDR97 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for WDR97 Gene

Domains & Families for WDR97 Gene

Gene Families for WDR97 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for WDR97 Gene

Suggested Antigen Peptide Sequences for WDR97 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with WDR97: view

No data available for UniProtKB/Swiss-Prot for WDR97 Gene

Function for WDR97 Gene

Phenotypes From GWAS Catalog for WDR97 Gene

genes like me logo Genes that share phenotypes with WDR97: view

Animal Model Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for WDR97 Gene

Localization for WDR97 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for WDR97 gene
Compartment Confidence
nucleus 3
cytosol 3

Gene Ontology (GO) - Cellular Components for WDR97 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IBA --
genes like me logo Genes that share ontologies with WDR97: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for WDR97 Gene

Pathways & Interactions for WDR97 Gene

SuperPathways for WDR97 Gene

No Data Available

Interacting Proteins for WDR97 Gene

Selected Interacting proteins: A6NE52-WDR97_HUMAN for WDR97 Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for WDR97 Gene


No data available for Pathways by source and SIGNOR curated interactions for WDR97 Gene

Drugs & Compounds for WDR97 Gene

No Compound Related Data Available

Transcripts for WDR97 Gene

mRNA/cDNA for WDR97 Gene

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for WDR97 Gene

No ASD Table

Relevant External Links for WDR97 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for WDR97 Gene

NURSA nuclear receptor signaling pathways regulating expression of WDR97 Gene:


Evidence on tissue expression from TISSUES for WDR97 Gene

  • Nervous system(4.2)
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for WDR97 Gene

Orthologs for WDR97 Gene

This gene was present in the common ancestor of chordates.

Orthologs for WDR97 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia KIAA1875 34
  • 98 (a)
(Canis familiaris)
Mammalia -- 34
  • 69 (a)
-- 34
  • 50 (a)
(Bos Taurus)
Mammalia KIAA1875 34
  • 65 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 58 (a)
-- 34
  • 45 (a)
-- 34
  • 32 (a)
(Monodelphis domestica)
Mammalia KIAA1875 34
  • 35 (a)
(Anolis carolinensis)
Reptilia KIAA1875 34
  • 36 (a)
Species where no ortholog for WDR97 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for WDR97 Gene

Gene Tree for WDR97 (if available)
Gene Tree for WDR97 (if available)

Paralogs for WDR97 Gene

No data available for Paralogs for WDR97 Gene

Variants for WDR97 Gene

Sequence variations from dbSNP and Humsavar for WDR97 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1000007447 -- 144,112,587(+) TTGTG(C/G)CTGCC intron-variant
rs1000481167 -- 144,107,419(+) TATTT(C/G)TACTG upstream-variant-2KB, utr-variant-3-prime
rs1000506680 -- 144,116,307(+) GTGGC(C/G)TCAGC utr-variant-3-prime
rs1000776481 -- 144,112,652(+) ACCTA(A/C)AACCA intron-variant
rs1000941571 -- 144,116,537(+) CCGGC(C/T)TAGGG downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for WDR97 Gene

Variant ID Type Subtype PubMed ID
nsv950015 CNV deletion 24416366
nsv824803 CNV gain 20364138
nsv824802 CNV gain 20364138
nsv6448 CNV insertion 18451855
nsv612915 CNV loss 21841781
nsv612914 CNV loss 21841781
nsv515809 CNV gain+loss 19592680
nsv470249 CNV loss 18288195
nsv466014 CNV loss 19166990
nsv428208 CNV gain 18775914
nsv1030888 CNV gain 25217958
nsv1025071 CNV gain 25217958
esv3619122 CNV gain 21293372
esv3619121 CNV loss 21293372
esv29971 CNV loss 17803354
esv2759651 CNV gain 17122850
dgv906n27 CNV loss 19166990
dgv12433n54 CNV gain 21841781
dgv12431n54 CNV loss 21841781

Variation tolerance for WDR97 Gene

Gene Damage Index Score: 5.26; 70.20% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for WDR97 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WDR97 Gene

Disorders for WDR97 Gene

Relevant External Links for WDR97

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for WDR97 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for WDR97 Gene

Publications for WDR97 Gene

  1. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11347906) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2001) 2 3 4 60
  2. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C … Lander ES (Nature 2006) 4 60
  3. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U … Wanker EE (Cell 2005) 3 60
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 60

Products for WDR97 Gene

Sources for WDR97 Gene

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