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Aliases for WDR93 Gene

Aliases for WDR93 Gene

  • WD Repeat Domain 93 2 3

External Ids for WDR93 Gene

Previous GeneCards Identifiers for WDR93 Gene

  • GC15P088036
  • GC15P090234
  • GC15P066346

Summaries for WDR93 Gene

GeneCards Summary for WDR93 Gene

WDR93 (WD Repeat Domain 93) is a Protein Coding gene. GO annotations related to this gene include oxidoreductase activity, acting on NAD(P)H.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR93 Gene

Genomics for WDR93 Gene

Regulatory Elements for WDR93 Gene

Genomic Location for WDR93 Gene

Start:
89,690,797 bp from pter
End:
89,743,655 bp from pter
Size:
52,859 bases
Orientation:
Plus strand

Genomic View for WDR93 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for WDR93 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WDR93 Gene

Proteins for WDR93 Gene

  • Protein details for WDR93 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6P2C0-WDR93_HUMAN
    Recommended name:
    WD repeat-containing protein 93
    Protein Accession:
    Q6P2C0
    Secondary Accessions:
    • Q8N7Y8
    • Q9NP89

    Protein attributes for WDR93 Gene

    Size:
    686 amino acids
    Molecular mass:
    77378 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for WDR93 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for WDR93 Gene

Proteomics data for WDR93 Gene at MOPED

Post-translational modifications for WDR93 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for WDR93 Gene

No data available for DME Specific Peptides for WDR93 Gene

Domains for WDR93 Gene

Gene Families for WDR93 Gene

HGNC:
  • WDR :WD repeat domain containing

Protein Domains for WDR93 Gene

Suggested Antigen Peptide Sequences for WDR93 Gene

Graphical View of Domain Structure for InterPro Entry

Q6P2C0

UniProtKB/Swiss-Prot:

WDR93_HUMAN :
  • Q6P2C0
Similarity:
  • Contains 1 WD repeat.
genes like me logo Genes that share domains with WDR93: view

Function for WDR93 Gene

Gene Ontology (GO) - Molecular Function for WDR93 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
GO:0016651 oxidoreductase activity, acting on NAD(P)H IEA --
genes like me logo Genes that share ontologies with WDR93: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for WDR93 Gene

Localization for WDR93 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for WDR93 Gene COMPARTMENTS Subcellular localization image for WDR93 gene
Compartment Confidence
nucleus 2
cytosol 1
endoplasmic reticulum 1
mitochondrion 1
peroxisome 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for WDR93 Gene

Pathways for WDR93 Gene

SuperPathways for WDR93 Gene

No Data Available

Interacting Proteins for WDR93 Gene

Gene Ontology (GO) - Biological Process for WDR93 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0022900 electron transport chain IEA --
genes like me logo Genes that share ontologies with WDR93: view

No data available for Pathways by source for WDR93 Gene

Transcripts for WDR93 Gene

Unigene Clusters for WDR93 Gene

WD repeat domain 93:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for WDR93 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18 ^ 19 ^ 20 ^ 21
SP1: - - - - -
SP2: - - - - - -
SP3:
SP4:
SP5:

Relevant External Links for WDR93 Gene

GeneLoc Exon Structure for
WDR93
ECgene alternative splicing isoforms for
WDR93

Expression for WDR93 Gene

mRNA expression in normal human tissues for WDR93 Gene

mRNA differential expression in normal tissues according to GTEx for WDR93 Gene

This gene is overexpressed in Testis (17.5).

SOURCE GeneReport for Unigene cluster for WDR93 Gene Hs.177557

genes like me logo Genes that share expressions with WDR93: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for WDR93 Gene

Orthologs for WDR93 Gene

This gene was present in the common ancestor of chordates.

Orthologs for WDR93 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia WDR93 35
  • 99.08 (n)
  • 98.83 (a)
WDR93 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia WDR93 36
  • 56 (a)
OneToOne
dog
(Canis familiaris)
Mammalia WDR93 35
  • 83.63 (n)
  • 76.9 (a)
WDR93 36
  • 77 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Wdr93 35
  • 75.97 (n)
  • 65.49 (a)
Wdr93 16
Wdr93 36
  • 63 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia WDR93 36
  • 47 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia WDR93 36
  • 48 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Wdr93 35
  • 75.7 (n)
  • 65.98 (a)
lizard
(Anolis carolinensis)
Reptilia WDR93 36
  • 34 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia wdr93 35
  • 52.99 (n)
  • 39.63 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC100149569 35
  • 46.32 (n)
  • 30.03 (a)
WDR93 36
  • 29 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 30 (a)
OneToOne
Species with no ortholog for WDR93:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for WDR93 Gene

ENSEMBL:
Gene Tree for WDR93 (if available)
TreeFam:
Gene Tree for WDR93 (if available)

Paralogs for WDR93 Gene

No data available for Paralogs for WDR93 Gene

Variants for WDR93 Gene

Sequence variations from dbSNP and Humsavar for WDR93 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs735985 -- 89,736,707(-) CACTC(C/T)CCCAC intron-variant
rs747774 -- 89,729,322(+) TGCCA(C/T)AGGAG intron-variant
rs747775 -- 89,729,462(+) CCCTA(C/T)GCAAG intron-variant
rs755253 -- 89,732,219(-) CTAGG(A/T)AAATA intron-variant
rs1371136 -- 89,731,975(-) GTTTG(C/T)GCTGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for WDR93 Gene

Variant ID Type Subtype PubMed ID
nsv1660 CNV Insertion 18451855
nsv904483 CNV Loss 21882294
esv268839 CNV Insertion 20981092
esv9488 CNV Gain 19470904
dgv2434n71 CNV Loss 21882294

Relevant External Links for WDR93 Gene

HapMap Linkage Disequilibrium report
WDR93
Human Gene Mutation Database (HGMD)
WDR93

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WDR93 Gene

Disorders for WDR93 Gene

Relevant External Links for WDR93

Genetic Association Database (GAD)
WDR93
genes like me logo Genes that share disorders with WDR93: view

No data available for UniProtKB/Swiss-Prot for WDR93 Gene

Publications for WDR93 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. A genome-wide association study of sporadic ALS in a homogenous Irish population. (PMID: 18057069) Cronin S. … Hardiman O. (Hum. Mol. Genet. 2008) 48
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for WDR93 Gene

Sources for WDR93 Gene

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