Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

WDR92 Gene

protein-coding   GIFtS: 46
GCID: GC02M068350

WD Repeat Domain 92

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
WD Repeat Domain 921 2
WD Repeat-Containing Protein Monad2 3
monad2
WD Repeat-Containing Protein 922
LOC1161435
MONAD5

External Ids:    HGNC: 251761   Entrez Gene: 1161432   Ensembl: ENSG000002436677   OMIM: 6107295   UniProtKB: Q96MX63   

Export aliases for WDR92 gene to outside databases

Previous GC identifers: GC02M068205 GC02M068094


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for WDR92 Gene:
This gene encodes a protein with two WD40 repeat domains thought to be involved in an apoptosis via activation of
caspase-3. Multiple transcript variants encoding different isoforms have been found for this gene. (provided by
RefSeq, Feb 2012)

GeneCards Summary for WDR92 Gene: 
WDR92 (WD repeat domain 92) is a protein-coding gene. Diseases associated with WDR92 include smallpox. GO annotations related to this gene include methylated histone residue binding. An important paralog of this gene is PPP3R1.

UniProtKB/Swiss-Prot: WDR92_HUMAN, Q96MX6
Function: Seems to act as a modulator of apoptosis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.2  NT_022184.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the WDR92 gene promoter:
         GR   Nkx3-1   Nkx3-1 v4   C/EBPbeta   p53   Nkx3-1 v1   NF-kappaB   Nkx3-1 v2   Nkx3-1 v3   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidWDR92 promoter sequence
   Search SABiosciences Chromatin IP Primers for WDR92

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WDR92


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p14   Ensembl cytogenetic band:  2p14   HGNC cytogenetic band: 2p14

WDR92 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WDR92 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M068350:  view genomic region     (about GC identifiers)

Start:
68,350,068 bp from pter      End:
68,384,692 bp from pter
Size:
34,625 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: WDR92_HUMAN, Q96MX6 (See protein sequence)
Recommended Name: WD repeat-containing protein 92  
Size: 357 amino acids; 39740 Da
1 PDB 3D structure from and Proteopedia for WDR92:
3I2N (3D)    
Secondary accessions: Q96CR6
Alternative splicing: 2 isoforms:  Q96MX6-1   Q96MX6-2   

Explore the universe of human proteins at neXtProt for WDR92: NX_Q96MX6

Explore proteomics data for WDR92 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96MX6

  • WDR92 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    WDR92 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001243405.1  NP_612467.1  

    ENSEMBL proteins: 
     ENSP00000295121   ENSP00000410301   ENSP00000384518   ENSP00000386746  

    Human Recombinant Protein Products for WDR92: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for WDR92
    OriGene Protein Over-expression Lysate for WDR92
    OriGene MassSpec for WDR92 
    OriGene Custom Protein Services for WDR92
    GenScript Custom Purified and Recombinant Proteins Services for WDR92
    Novus Biologicals WDR92 Proteins
    Novus Biologicals WDR92 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 


    WDR92 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for WDR92
    GenScript Custom Superior Antibodies Services for WDR92
    Novus Biologicals WDR92 Antibodies
    Abcam antibodies for WDR92
    Browse Antibodies at Cloud-Clone Corp. 
    ThermoFisher Antibodies for WDR92
    LSBio Antibodies in human, mouse, rat for WDR92 

    Assay Products for WDR92: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for WDR92
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for WDR92
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    WDR: WD repeat domain containing

    3 InterPro protein domains:
     IPR001680 WD40_repeat
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q96MX6

    ProtoNet protein and cluster: Q96MX6

    UniProtKB/Swiss-Prot: WDR92_HUMAN, Q96MX6
    Similarity: Contains 6 WD repeats


    WDR92 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: WDR92_HUMAN, Q96MX6
    Function: Seems to act as a modulator of apoptosis

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI18538670
    GO:0035064methylated histone residue binding IDA16600877
         
    WDR92 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for WDR92 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for WDR92

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for WDR92 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for WDR92 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat WDR92
    6 QIAGEN miScript miRNA Assays for microRNAs that regulate WDR92:
    hsa-miR-375 hsa-miR-1264 hsa-miR-216b hsa-miR-616* hsa-miR-371-5p hsa-miR-373*
    SwitchGear 3'UTR luciferase reporter plasmidWDR92 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for WDR92
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat WDR92

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for WDR92
    Sirion Biotech Customized adenovirus for overexpression of WDR92

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for WDR92 (see all 8)
    OriGene ORF clones in mouse, rat for WDR92
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: WDR92 (NM_138458)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for WDR92
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR92
    Sirion Biotech Customized lentivirus for stable overexpression of WDR92 
                         Customized lentivirus expression plasmids for stable overexpression of WDR92 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for WDR92
    Search LifeMap BioReagents cell lines for WDR92
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR92


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for WDR92

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/7 Interacting proteins for WDR92 (Q96MX62, 3 ENSP000002951214) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPAP3Q9H6T32, 3, ENSP000000053864MINT-6551118 MINT-6551132 MINT-6551090 MINT-6551101 I2D: score=1 STRING: ENSP00000005386
    PARD6AQ9NPB63, ENSP000002192554I2D: score=2 STRING: ENSP00000219255
    PRPF8ENSP000003043504STRING: ENSP00000304350
    ECDENSP000004015664STRING: ENSP00000401566
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process IEA--
    GO:0034968histone lysine methylation IDA16600877

    WDR92 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for WDR92

    Search CenterWatch for drugs/clinical trials and news about WDR92

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for WDR92 gene (2 alternative transcripts): 
    NM_001256476.1  NM_138458.3  

    Unigene Cluster for WDR92:

    WD repeat domain 92
    Hs.631877  [show with all ESTs]
    Unigene Representative Sequence: AL834142
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000492039(uc002sed.1) ENST00000295121(uc002see.1) ENST00000457114
    ENST00000406245 ENST00000409164(uc002sef.1 uc002seg.1) ENST00000468984

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat WDR92
    6 QIAGEN miScript miRNA Assays for microRNAs that regulate WDR92:
    hsa-miR-375 hsa-miR-1264 hsa-miR-216b hsa-miR-616* hsa-miR-371-5p hsa-miR-373*
    SwitchGear 3'UTR luciferase reporter plasmidWDR92 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for WDR92
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat WDR92
    Clone
    Products:
         
    OriGene clones in human, mouse for WDR92 (see all 8)
    OriGene ORF clones in mouse, rat for WDR92
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: WDR92 (NM_138458)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for WDR92
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR92
    Sirion Biotech Customized lentivirus for stable overexpression of WDR92 
                         Customized lentivirus expression plasmids for stable overexpression of WDR92 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for WDR92
    OriGene qSTAR qPCR primer pairs in human, mouse for WDR92
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat WDR92
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDR92
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR92

    Additional mRNA sequence: 

    AK056303.1 AK058090.1 AL834142.1 AY541587.1 BC014022.2 BC020271.1 BC036904.1 BC066657.1 
    NR_046234.1 

    8 DOTS entries:

    DT.40195773  DT.40206172  DT.100735333  DT.453079  DT.40125810  DT.102833044  DT.103697  DT.40196285 

    24/430 AceView cDNA sequences (see all 430):

    W01341 CK820228 CF455458 BQ228635 CB306200 BU628390 AW014787 BX109819 
    BU177986 BX340492 CR593156 NM_006333 AI493088 AA805413 BU675203 BM354091 
    BP350152 AA019009 AI476631 BC066657 AI375251 BM714895 AI285866 BC020271 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    WDR92 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCGGGCATCT
    WDR92 Expression
    About this image


    See WDR92 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for WDR92

    SOURCE GeneReport for Unigene cluster: Hs.631877

    UniProtKB/Swiss-Prot: WDR92_HUMAN, Q96MX6
    Tissue specificity: Widely expressed with the highest expression in testis

        SABiosciences Custom PCR Arrays for WDR92
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for WDR92
    OriGene qSTAR qPCR primer pairs in human, mouse for WDR92
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat WDR92
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDR92
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR92
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR92

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for WDR92 gene from 8/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Wdr921 , 5 WD repeat domain 921, 5 88.24(n)1
    93.56(a)1
      11 (9.75 cM)5
    1037841  NM_178909.41  NP_849240.11 
     171821075 
    chicken
    (Gallus gallus)
    Aves WDR921 WD repeat domain 92 79.7(n)
    90.1(a)
      769534  NM_001079744.1  NP_001073212.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    43(a)
    possible ortholog
    1(126546387-126637462)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.164002 Xenopus laevis transcribed sequence with weak similarity to protein refNP_037361.1 (H.sapiens) apoptotic protease activating factor isoform a; apoptotic protease activating factor 1 [Homo sapiens] less 78.66(n)    CD301610.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BI428243.12   -- 71.88(n)    BI428243.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG143531 CG14353 58.97(n)
    59.26(a)
      39997  NM_140768.2  NP_649025.1 
    worm
    (Caenorhabditis elegans)
    Secernentea cnb-16
    Protein CNB-1, isoform b
    2(a)
    possible ortholog
    V(11375742-11378057)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes CNB16
    Calcineurin B; the regulatory subunit of calcineur...
    1(a)
    1 → many
    XI(82947-83550)


    ENSEMBL Gene Tree for WDR92 (if available)
    TreeFam Gene Tree for WDR92 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for WDR92 gene
    PPP3R12  PPP3R22  CHP22  CHP12  
    2 SIMAP similar genes for WDR92 using alignment to 2 protein entries:     WDR92_HUMAN (see all proteins):
    DKFZp434B156    HZGJ

    WDR92 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/686 SNPs in WDR92 are shown (see all 686)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1812585271,2
    --68214048(+) TGGGAA/GGCCAA 1 -- ds50010--------
    rs1382147381,2
    --68214146(+) CCAGAC/TATGGT 1 -- ds50010--------
    rs1853211771,2
    --68214179(+) TACTCA/GGGAGG 1 -- ds50010--------
    rs1905287151,2
    --68214201(+) GAATCA/GCTTGA 1 -- ds50010--------
    rs1144913821,2
    C,F--68214454(+) TCTAGA/GGACAG 1 -- ds50011Minor allele frequency- G:0.03NA 120
    rs1832354041,2
    --68214497(+) TCACTA/GTCTTT 1 -- ds50010--------
    rs1869609081,2
    --68214612(+) TCAAGA/CGATTC 1 -- int10--------
    rs75996871,2
    C,F,H--68214911(+) ATTCAT/CAACAA 1 -- int131Minor allele frequency- C:0.26NS EA NA WA CSA 2906
    rs1921014361,2
    --68214924(+) CCTAAA/GTGGCC 1 -- int10--------
    rs729088361,2
    C,F--68214956(+) GTGGCC/GGTCAG 1 -- int12Minor allele frequency- G:0.17WA 120

    HapMap Linkage Disequilibrium report for WDR92 (68350068 - 68384692 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for WDR92:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv834251CNV Loss17160897

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing WDR92
    DNA2.0 Custom Variant and Variant Library Synthesis for WDR92

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610729    OMIM disorders: --

    2 diseases for WDR92:    About MalaCards
    smallpox    


    WDR92 for disorders           About GeneDecksing


    Export disorders for WDR92 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for WDR92 gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with WDR92)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Monad, a WD40 repeat protein, promotes apoptosis induced by TNF- alpha. (PubMed id 16487927)1, 2, 3 Saeki M.... Kamisaki Y. (2006)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    4. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    5. Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients. (PubMed id 22610502)1 Kennedy R.B....Poland G.A. (2012)
    6. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    7. Structure and function of WD40 domain proteins. (PubMed id 21468892)2 Xu C. and Min J. (2011)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    10. High-resolution mapping of the protein interaction ne twork for the human transcription machinery and affinity purification of RNA po lymerase II-associated complexes. (PubMed id 19450687)1 Cloutier P....Coulombe B. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 116143 HGNC: 25176 AceView: PPP3R1andC1DandLOC116143 Ensembl:ENSG00000243667 euGenes: HUgn116143
    ECgene: WDR92 H-InvDB: WDR92

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for WDR92 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for WDR92 gene:
    Search GeneIP for patents involving WDR92

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for WDR92  
     OriGene qPCR primer pairs and template standards for WDR92   OriGene Protein Over-expression Lysate for WDR92  
     OriGene MassSpec something-or-other for WDR92   OriGene clones in human, mouse for WDR92  
     OriGene qSTAR qPCR primer pairs in human, mouse for WDR92   OriGene Purified Protein for WDR92  
     OriGene ORF clones in mouse, rat for WDR92   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for WDR92   OriGene Custom Protein Services for WDR92  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat WDR92
     QIAGEN SeqTarget long-range PCR primers for resequencing WDR92
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WDR92
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat WDR92
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR92
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDR92
     GenScript Custom Purified and Recombinant Proteins Services for WDR92 GenScript cDNA clones with any tag delivered in your preferred vector for WDR92
     GenScript Custom Assay Services for WDR92 GenScript Custom Superior Antibodies Services for WDR92
     GenScript Custom overexpressing Cell Line Services for WDR92 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in WDR92 promoter
     Search Chromatin IP Primers for WDR92
     RT2 qPCR Primer Assay in human, mouse, rat WDR92
     Search GNC Networks for WDR92
     SABiosciences Custom PCR Arrays for WDR92
     Search Tocris compounds for WDR92
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     WDR92 antibodies
     WDR92 proteins
     WDR92 lysates
     Antibodies for WDR92
     See all of Abcam's Antibodies, Kits and Proteins for WDR92
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.
     Search LifeMap BioReagents cell lines for WDR92
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR92
     SwitchGear 3'UTR luciferase reporter plasmids for WDR92
     SwitchGear Promoter luciferase reporter plasmids for WDR92
     ThermoFisher Antibodies for WDR92
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR92
     inGenious Targeting Laboratory - Custom generated mouse model solutions for WDR92
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for WDR92
    Customized:
     lentivirus for stable overexpression of WDR92
     lentivirus expression plasmids for stable overexpression of WDR92
     adenovirus for overexpression of WDR92
     LSBio Antibodies in human, mouse, rat for WDR92
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      WDR92 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4