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Aliases for WDR90 Gene

Aliases for WDR90 Gene

  • WD Repeat Domain 90 2 3
  • C16ORF15 3 4
  • C16orf16 3 4
  • C16orf17 3 4
  • C16orf18 3 4
  • C16orf19 3 4
  • Chromosome 16 Open Reading Frame 17 2
  • Chromosome 16 Open Reading Frame 15 2
  • Chromosome 16 Open Reading Frame 16 2
  • Chromosome 16 Open Reading Frame 19 2
  • Chromosome 16 Open Reading Frame 18 2
  • WD Repeat-Containing Protein 90 3
  • KIAA1924 4

External Ids for WDR90 Gene

Previous HGNC Symbols for WDR90 Gene

  • C16orf17
  • C16orf15
  • C16orf16
  • C16orf19
  • C16orf18

Previous GeneCards Identifiers for WDR90 Gene

  • GC16P000644
  • GC16P000645
  • GC16P000699
  • GC16P000624

Summaries for WDR90 Gene

GeneCards Summary for WDR90 Gene

WDR90 (WD Repeat Domain 90) is a Protein Coding gene. An important paralog of this gene is CFAP52.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR90 Gene

Genomics for WDR90 Gene

Regulatory Elements for WDR90 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for WDR90 Gene

Start:
649,311 bp from pter
End:
667,833 bp from pter
Size:
18,523 bases
Orientation:
Plus strand

Genomic View for WDR90 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for WDR90 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WDR90 Gene

Proteins for WDR90 Gene

  • Protein details for WDR90 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96KV7-WDR90_HUMAN
    Recommended name:
    WD repeat-containing protein 90
    Protein Accession:
    Q96KV7
    Secondary Accessions:
    • Q0VA87
    • Q0VA88
    • Q6P048
    • Q6ZMS1
    • Q6ZTH1
    • Q8N202
    • Q8N221
    • Q8NBB8
    • Q96PW4
    • Q96S18

    Protein attributes for WDR90 Gene

    Size:
    1748 amino acids
    Molecular mass:
    187437 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAK61239.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=BAB67817.1; Type=Miscellaneous discrepancy; Note=Intron retention.; Evidence={ECO:0000305}; Sequence=BAC03575.1; Type=Miscellaneous discrepancy; Note=Unlikely isoform. Aberrant splicing.; Evidence={ECO:0000305}; Sequence=BAC04225.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAC04225.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305}; Sequence=BAD18654.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305}; Sequence=EAW85775.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for WDR90 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for WDR90 Gene

Proteomics data for WDR90 Gene at MOPED

Post-translational modifications for WDR90 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for WDR90 Gene

Domains for WDR90 Gene

Gene Families for WDR90 Gene

HGNC:
  • WDR :WD repeat domain containing

Suggested Antigen Peptide Sequences for WDR90 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96KV7

UniProtKB/Swiss-Prot:

WDR90_HUMAN :
  • Q96KV7
Similarity:
  • Contains 21 WD repeats.
genes like me logo Genes that share domains with WDR90: view

Function for WDR90 Gene

Gene Ontology (GO) - Molecular Function for WDR90 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with WDR90: view

Phenotypes for WDR90 Gene

GenomeRNAi human phenotypes for WDR90:
genes like me logo Genes that share phenotypes with WDR90: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for WDR90 Gene

Localization for WDR90 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for WDR90 Gene COMPARTMENTS Subcellular localization image for WDR90 gene
Compartment Confidence
nucleus 2
cytosol 1
mitochondrion 1
peroxisome 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for WDR90 Gene

Pathways for WDR90 Gene

SuperPathways for WDR90 Gene

No Data Available

Gene Ontology (GO) - Biological Process for WDR90 Gene

None

No data available for Pathways by source for WDR90 Gene

Transcripts for WDR90 Gene

Unigene Clusters for WDR90 Gene

WD repeat domain 90:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for WDR90

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for WDR90
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for WDR90 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12 ^ 13a · 13b ^ 14a · 14b · 14c ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^
SP1:
SP2:
SP3:
SP4:
SP5: - -
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:

ExUns: 21a · 21b ^ 22a · 22b ^ 23 ^ 24 ^ 25 ^ 26 ^ 27a · 27b ^ 28 ^ 29 ^ 30a · 30b ^ 31 ^ 32a · 32b · 32c ^ 33 ^ 34a · 34b · 34c ^ 35a · 35b ^ 36
SP1: - -
SP2: -
SP3:
SP4:
SP5:
SP6: -
SP7:
SP8:
SP9:
SP10: - -
SP11:
SP12:
SP13:

Relevant External Links for WDR90 Gene

GeneLoc Exon Structure for
WDR90
ECgene alternative splicing isoforms for
WDR90

Expression for WDR90 Gene

mRNA expression in normal human tissues for WDR90 Gene

mRNA differential expression in normal tissues according to GTEx for WDR90 Gene

This gene is overexpressed in Testis (4.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for WDR90 Gene

SOURCE GeneReport for Unigene cluster for WDR90 Gene Hs.511903

genes like me logo Genes that share expressions with WDR90: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for WDR90 Gene

Orthologs for WDR90 Gene

This gene was present in the common ancestor of animals.

Orthologs for WDR90 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia WDR90 35
  • 97.7 (n)
  • 97.41 (a)
WDR90 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia WDR90 35
  • 77.64 (n)
  • 71.82 (a)
WDR90 36
  • 68 (a)
OneToOne
dog
(Canis familiaris)
Mammalia WDR90 35
  • 75.15 (n)
  • 67.57 (a)
WDR90 36
  • 66 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Wdr90 35
  • 75.62 (n)
  • 71.99 (a)
Wdr90 16
Wdr90 36
  • 66 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia WDR90 36
  • 56 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia WDR90 36
  • 53 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC102555298 35
  • 76.36 (n)
  • 72.59 (a)
chicken
(Gallus gallus)
Aves WDR90 36
  • 60 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia WDR90 36
  • 51 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia wdr90 35
  • 60.97 (n)
  • 56.32 (a)
zebrafish
(Danio rerio)
Actinopterygii wdr90 35
  • 55.28 (n)
  • 49.65 (a)
wdr90 36
  • 45 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG10064 36
  • 18 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 33 (a)
OneToOne
Species with no ortholog for WDR90:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for WDR90 Gene

ENSEMBL:
Gene Tree for WDR90 (if available)
TreeFam:
Gene Tree for WDR90 (if available)

Paralogs for WDR90 Gene

Paralogs for WDR90 Gene

genes like me logo Genes that share paralogs with WDR90: view

Variants for WDR90 Gene

Sequence variations from dbSNP and Humsavar for WDR90 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs1044662 -- 665,060(+) GCTTC(C/T)TCTCA intron-variant
rs1044663 -- 665,161(+) CAATC(A/G)GCGTG intron-variant
rs1057834 -- 662,758(+) TGGGC(A/G)TCGTG missense, reference, intron-variant, nc-transcript-variant
rs1057835 -- 662,867(+) TGGGC(A/G)GAGGC intron-variant, nc-transcript-variant
rs2071831 -- 658,071(-) GGCAG(C/G)ACCTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for WDR90 Gene

Variant ID Type Subtype PubMed ID
esv2422427 CNV Duplication 17116639
nsv904707 CNV Loss 21882294
nsv526903 CNV Loss 19592680
dgv2475n71 CNV Loss 21882294
dgv2479n71 CNV Loss 21882294
nsv833114 CNV Gain+Loss 17160897
nsv471063 CNV Loss 18288195
dgv2484n71 CNV Loss 21882294
dgv2485n71 CNV Loss 21882294
nsv904759 CNV Loss 21882294
dgv334n27 CNV Loss 19166990
nsv904760 CNV Loss 21882294
dgv2487n71 CNV Loss 21882294
nsv516590 CNV Loss 19592680
dgv2488n71 CNV Loss 21882294
nsv904779 CNV Loss 21882294
nsv904781 CNV Gain 21882294
nsv471065 CNV Gain 18288195
dgv2489n71 CNV Loss 21882294
nsv904785 CNV Gain+Loss 21882294
dgv2490n71 CNV Loss 21882294
nsv9321 CNV Gain+Loss 18304495
nsv457310 CNV Loss 19166990
dgv2491n71 CNV Loss 21882294
nsv904796 CNV Loss 21882294
nsv904797 CNV Loss 21882294
nsv827479 CNV Gain 20364138
esv2750220 CNV Deletion 23290073
dgv2492n71 CNV Loss 21882294
esv2750221 CNV Deletion 23290073
esv1011191 CNV Deletion 20482838
esv2750222 CNV Deletion 23290073
esv2750223 CNV Deletion 23290073
nsv103377 CNV Loss 16902084
nsv904799 CNV Loss 21882294

Relevant External Links for WDR90 Gene

HapMap Linkage Disequilibrium report
WDR90

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WDR90 Gene

Disorders for WDR90 Gene

No disorders were found for WDR90 Gene.

No data available for UniProtKB/Swiss-Prot for WDR90 Gene

Publications for WDR90 Gene

  1. Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. (PMID: 11157797) Daniels R.J. … Higgs D.R. (Hum. Mol. Genet. 2001) 2 3 4
  2. Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PMID: 11572484) Nagase T. … Ohara O. (DNA Res. 2001) 2 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network. (PMID: 23446634) Chen Z. … Reiner A.P. (Hum. Mol. Genet. 2013) 3
  5. Novel Cul3 binding proteins function to remodel E3 ligase complexes. (PMID: 25011449) Wimuttisuk W. … Singer J.D. (BMC Cell Biol. 2014) 3

Products for WDR90 Gene

Sources for WDR90 Gene

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