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Aliases for WDR89 Gene

Aliases for WDR89 Gene

  • WD Repeat Domain 89 2 3
  • C14orf150 3 4
  • MSTP050 3

External Ids for WDR89 Gene

Previous HGNC Symbols for WDR89 Gene

  • C14orf150

Previous GeneCards Identifiers for WDR89 Gene

  • GC14M063135
  • GC14M064063
  • GC14M044230

Summaries for WDR89 Gene

GeneCards Summary for WDR89 Gene

WDR89 (WD Repeat Domain 89) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR89 Gene

Genomics for WDR89 Gene

Regulatory Elements for WDR89 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for WDR89 Gene

63,597,039 bp from pter
63,641,923 bp from pter
44,885 bases
Minus strand

Genomic View for WDR89 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for WDR89 Gene

Proteins for WDR89 Gene

  • Protein details for WDR89 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    WD repeat-containing protein 89
    Protein Accession:

    Protein attributes for WDR89 Gene

    387 amino acids
    Molecular mass:
    43215 Da
    Quaternary structure:
    No Data Available

neXtProt entry for WDR89 Gene

Proteomics data for WDR89 Gene at MOPED

Post-translational modifications for WDR89 Gene

  • Ubiquitination at Lys 95
  • Modification sites at PhosphoSitePlus

Other Protein References for WDR89 Gene

No data available for DME Specific Peptides for WDR89 Gene

Domains & Families for WDR89 Gene

Gene Families for WDR89 Gene

Protein Domains for WDR89 Gene

Suggested Antigen Peptide Sequences for WDR89 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 6 WD repeats.
  • Contains 6 WD repeats.
genes like me logo Genes that share domains with WDR89: view

Function for WDR89 Gene

Gene Ontology (GO) - Molecular Function for WDR89 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with WDR89: view

Phenotypes for WDR89 Gene

genes like me logo Genes that share phenotypes with WDR89: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for WDR89 Gene

Localization for WDR89 Gene

Subcellular locations from

Jensen Localization Image for WDR89 Gene COMPARTMENTS Subcellular localization image for WDR89 gene
Compartment Confidence
cytoskeleton 2
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for WDR89 Gene

Pathways & Interactions for WDR89 Gene

SuperPathways for WDR89 Gene

No Data Available

Interacting Proteins for WDR89 Gene

STRING Interaction Network Preview (showing 4 interactants - click image to see details)
Selected Interacting proteins: Q96FK6-WDR89_HUMAN ENSP00000267522 for WDR89 Gene via I2D STRING

Gene Ontology (GO) - Biological Process for WDR89 Gene


No data available for Pathways by source and SIGNOR curated interactions for WDR89 Gene

Drugs & Compounds for WDR89 Gene

No Compound Related Data Available

Transcripts for WDR89 Gene

Unigene Clusters for WDR89 Gene

WD repeat domain 89:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for WDR89 Gene

No ASD Table

Relevant External Links for WDR89 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for WDR89 Gene

mRNA expression in normal human tissues for WDR89 Gene

Protein differential expression in normal tissues from HIPED for WDR89 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (17.5), Lung (16.8), and CD4 Tcells (7.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for WDR89 Gene

SOURCE GeneReport for Unigene cluster for WDR89 Gene Hs.655666

genes like me logo Genes that share expression patterns with WDR89: view

Protein tissue co-expression partners for WDR89 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for WDR89 Gene

Orthologs for WDR89 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for WDR89 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia WDR89 35
  • 88.43 (n)
  • 86.01 (a)
WDR89 36
  • 86 (a)
(Canis familiaris)
Mammalia WDR89 35
  • 89.75 (n)
  • 86.82 (a)
WDR89 36
  • 87 (a)
(Mus musculus)
Mammalia Wdr89 35
  • 81.26 (n)
  • 81.09 (a)
Wdr89 16
Wdr89 36
  • 81 (a)
(Pan troglodytes)
Mammalia WDR89 35
  • 99.48 (n)
  • 99.22 (a)
WDR89 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Wdr89 35
  • 82.04 (n)
  • 81.87 (a)
(Monodelphis domestica)
Mammalia WDR89 36
  • 62 (a)
(Ornithorhynchus anatinus)
Mammalia WDR89 36
  • 65 (a)
(Gallus gallus)
Aves WDR89 35
  • 67.1 (n)
  • 63.64 (a)
WDR89 36
  • 55 (a)
(Anolis carolinensis)
Reptilia WDR89 36
  • 64 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.16071 35
wdr89 35
  • 66.4 (n)
  • 56.43 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.17137 35
(Danio rerio)
Actinopterygii wdr89 35
  • 53.24 (n)
  • 43.78 (a)
WDR89 36
  • 42 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP005524 35
  • 42.26 (n)
  • 33.83 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG12134 35
  • 44.01 (n)
  • 33.33 (a)
CG12134 36
  • 24 (a)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_ADL218C 35
  • 40 (n)
  • 31.23 (a)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0E08449g 35
  • 47.13 (n)
  • 33.19 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes YNL035C 35
  • 42.69 (n)
  • 36.95 (a)
-- 36
  • 25 (a)
-- 38
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G47790 35
  • 48.27 (n)
  • 33.69 (a)
(Oryza sativa)
Liliopsida Os12g0294100 35
  • 47.67 (n)
  • 33.52 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU02570 35
  • 41.93 (n)
  • 34.39 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPCC63.06 35
  • 43.76 (n)
  • 27.89 (a)
Species with no ortholog for WDR89:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for WDR89 Gene

Gene Tree for WDR89 (if available)
Gene Tree for WDR89 (if available)

Paralogs for WDR89 Gene Pseudogenes for WDR89 Gene

genes like me logo Genes that share paralogs with WDR89: view

No data available for Paralogs for WDR89 Gene

Variants for WDR89 Gene

Sequence variations from dbSNP and Humsavar for WDR89 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs1255725 -- 63,639,979(-) TCACT(G/T)TGTAA intron-variant
rs1255726 -- 63,639,594(-) TCAAT(A/G)TTTTA intron-variant
rs1255727 -- 63,634,744(-) ttata(A/G)gcatg intron-variant
rs1266816 -- 63,630,638(-) tgaga(A/C)agagt intron-variant, upstream-variant-2KB
rs1271026 -- 63,602,351(-) tggat(A/T)acagg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for WDR89 Gene

Variant ID Type Subtype PubMed ID
dgv137n21 CNV Gain 19592680
nsv528691 CNV Gain 19592680
esv2677727 CNV Deletion 23128226

Variation tolerance for WDR89 Gene

Residual Variation Intolerance Score: 40.44% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.52; 11.33% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for WDR89 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WDR89 Gene

Disorders for WDR89 Gene

Relevant External Links for WDR89

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with WDR89: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for WDR89 Gene

Publications for WDR89 Gene

  1. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  3. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 67
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 67
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 67

Products for WDR89 Gene

Sources for WDR89 Gene

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