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Aliases for WDR89 Gene

Aliases for WDR89 Gene

  • WD Repeat Domain 89 2 3
  • C14orf150 3 4
  • WD Repeat-Containing Protein 89 3
  • MSTP050 3

External Ids for WDR89 Gene

Previous Symbols for WDR89 Gene

  • C14orf150

Summaries for WDR89 Gene

GeneCards Summary for WDR89 Gene

WDR89 (WD Repeat Domain 89) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR89 Gene

Genomics for WDR89 Gene

Genomic Location for WDR89 Gene

Start:
63,597,039 bp from pter
End:
63,641,923 bp from pter
Size:
44,885 bases
Orientation:
Minus strand

Genomic View for WDR89 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for WDR89 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WDR89 Gene

Regulatory Elements for WDR89 Gene

Proteins for WDR89 Gene

  • Protein details for WDR89 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96FK6-WDR89_HUMAN
    Recommended name:
    WD repeat-containing protein 89
    Protein Accession:
    Q96FK6
    Secondary Accessions:

    Protein attributes for WDR89 Gene

    Size:
    387 amino acids
    Molecular mass:
    43215 Da
    Quaternary structure:
    No Data Available

neXtProt entry for WDR89 Gene

Proteomics data for WDR89 Gene at MOPED

Post-translational modifications for WDR89 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys95

Other Protein References for WDR89 Gene

No data available for DME Specific Peptides for WDR89 Gene

Domains for WDR89 Gene

Gene Families for WDR89 Gene

HGNC:
  • WDR :WD repeat domain containing

Protein Domains for WDR89 Gene

UniProtKB/Swiss-Prot:

WDR89_HUMAN
Similarity:
  • Contains 6 WD repeats.:
    • Q96FK6
genes like me logo Genes that share domains with WDR89: view

Function for WDR89 Gene

Gene Ontology (GO) - Molecular Function for WDR89 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with WDR89: view

miRNA for WDR89 Gene

miRTarBase miRNAs that target WDR89

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for WDR89 Gene

Localization for WDR89 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for WDR89 Gene COMPARTMENTS Subcellular localization image for WDR89 gene
Compartment Confidence
cytosol 2
nucleus 2
cytoskeleton 1

No data available for Gene Ontology (GO) - Cellular Components for WDR89 Gene

Pathways for WDR89 Gene

SuperPathways for WDR89 Gene

No Data Available

Interacting Proteins for WDR89 Gene

STRING Interaction Network Preview (showing 4 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000267522%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000381034%0d%0a9606.ENSP00000341327%0d%0a9606.ENSP00000366828%0d%0a
Selected Interacting proteins: ENSP00000267522 Q96FK6-WDR89_HUMAN for WDR89 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for WDR89 Gene

None

No data available for Pathways by source for WDR89 Gene

Transcripts for WDR89 Gene

Unigene Clusters for WDR89 Gene

WD repeat domain 89:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for WDR89 Gene

No ASD Table

Relevant External Links for WDR89 Gene

GeneLoc Exon Structure for
WDR89
ECgene alternative splicing isoforms for
WDR89

Expression for WDR89 Gene

mRNA expression in normal human tissues for WDR89 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for WDR89 Gene

SOURCE GeneReport for Unigene cluster for WDR89 Gene Hs.655666

genes like me logo Genes that share expressions with WDR89: view

Orthologs for WDR89 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for WDR89 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia WDR89 36
  • 99.48 (n)
  • 99.22 (a)
WDR89 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia WDR89 36
  • 88.43 (n)
  • 86.01 (a)
WDR89 37
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia WDR89 36
  • 89.75 (n)
  • 86.82 (a)
WDR89 37
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Wdr89 36
  • 81.26 (n)
  • 81.09 (a)
Wdr89 16
Wdr89 37
  • 81 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia WDR89 37
  • 62 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia WDR89 37
  • 65 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Wdr89 36
  • 82.04 (n)
  • 81.87 (a)
chicken
(Gallus gallus)
Aves WDR89 36
  • 67.1 (n)
  • 63.64 (a)
WDR89 37
  • 55 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia WDR89 37
  • 64 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.17137 36
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.16071 36
wdr89 36
  • 66.4 (n)
  • 56.43 (a)
zebrafish
(Danio rerio)
Actinopterygii wdr89 36
  • 53.24 (n)
  • 43.78 (a)
WDR89 37
  • 42 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP005524 36
  • 42.26 (n)
  • 33.83 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG12134 36
  • 44.01 (n)
  • 33.33 (a)
CG12134 37
  • 24 (a)
OneToOne
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_ADL218C 36
  • 40 (n)
  • 31.23 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 37
  • 25 (a)
OneToOne
-- 39
YNL035C 36
  • 42.69 (n)
  • 36.95 (a)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0E08449g 36
  • 47.13 (n)
  • 33.19 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G47790 36
  • 48.27 (n)
  • 33.69 (a)
rice
(Oryza sativa)
Liliopsida Os12g0294100 36
  • 47.67 (n)
  • 33.52 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU02570 36
  • 41.93 (n)
  • 34.39 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPCC63.06 36
  • 43.76 (n)
  • 27.89 (a)
Species with no ortholog for WDR89:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for WDR89 Gene

ENSEMBL:
Gene Tree for WDR89 (if available)
TreeFam:
Gene Tree for WDR89 (if available)

Paralogs for WDR89 Gene

Pseudogenes.org Pseudogenes for WDR89 Gene

genes like me logo Genes that share paralogs with WDR89: view

No data available for Paralogs for WDR89 Gene

Variants for WDR89 Gene

Sequence variations from dbSNP and Humsavar for WDR89 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs1255725 -- 63,639,979(-) TCACT(G/T)TGTAA intron-variant
rs1255726 -- 63,639,594(-) TCAAT(A/G)TTTTA intron-variant
rs1255727 -- 63,634,744(-) ttata(A/G)gcatg intron-variant
rs1266816 -- 63,630,638(-) tgaga(A/C)agagt intron-variant
rs1271026 -- 63,602,351(-) tggat(A/T)acagg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for WDR89 Gene

Variant ID Type Subtype PubMed ID
dgv137n21 CNV Gain 19592680
nsv528691 CNV Gain 19592680
esv2677727 CNV Deletion 23128226

Relevant External Links for WDR89 Gene

HapMap Linkage Disequilibrium report
WDR89

Disorders for WDR89 Gene

No disorders were found for WDR89 Gene.

No data available for UniProtKB/Swiss-Prot for WDR89 Gene

Publications for WDR89 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PMID: 15342556) Suzuki Y. … Sugano S. (Genome Res. 2004) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Nucleolar proteome dynamics. (PMID: 15635413) Andersen J.S. … Mann M. (Nature 2005) 3

Products for WDR89 Gene

Sources for WDR89 Gene

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