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Aliases for WDR87 Gene

Aliases for WDR87 Gene

  • WD Repeat Domain 87 2 3
  • Testis Development Protein NYD-SP11 3 4
  • WD Repeat-Containing Protein 87 3
  • NYD-SP11 3

External Ids for WDR87 Gene

Previous GeneCards Identifiers for WDR87 Gene

  • GC19M043069
  • GC19M038376
  • GC19M034824

Summaries for WDR87 Gene

GeneCards Summary for WDR87 Gene

WDR87 (WD Repeat Domain 87) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR87 Gene

Genomics for WDR87 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for WDR87 Gene

Start:
37,884,573 bp from pter
End:
37,906,677 bp from pter
Size:
22,105 bases
Orientation:
Minus strand

Genomic View for WDR87 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for WDR87 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WDR87 Gene

No data available for Regulatory Elements for WDR87 Gene

Proteins for WDR87 Gene

  • Protein details for WDR87 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZQQ6-WDR87_HUMAN
    Recommended name:
    WD repeat-containing protein 87
    Protein Accession:
    Q6ZQQ6
    Secondary Accessions:
    • Q9BWV9

    Protein attributes for WDR87 Gene

    Size:
    2873 amino acids
    Molecular mass:
    333185 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAK20167.2; Type=Erroneous termination; Positions=825; Note=Translated as Trp.; Evidence={ECO:0000305}; Sequence=AAK20167.2; Type=Frameshift; Positions=126, 820, 1129, 1140; Evidence={ECO:0000305};

    Alternative splice isoforms for WDR87 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for WDR87 Gene

Proteomics data for WDR87 Gene at MOPED

Post-translational modifications for WDR87 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for WDR87 Gene

No data available for DME Specific Peptides for WDR87 Gene

Domains for WDR87 Gene

Gene Families for WDR87 Gene

HGNC:
  • WDR :WD repeat domain containing

Suggested Antigen Peptide Sequences for WDR87 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6ZQQ6

UniProtKB/Swiss-Prot:

WDR87_HUMAN :
  • Q6ZQQ6
Similarity:
  • Contains 7 WD repeats.
genes like me logo Genes that share domains with WDR87: view

Function for WDR87 Gene

Gene Ontology (GO) - Molecular Function for WDR87 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity --
GO:0005488 binding --
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with WDR87: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for WDR87 Gene

Localization for WDR87 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for WDR87 Gene COMPARTMENTS Subcellular localization image for WDR87 gene
Compartment Confidence
nucleus 2
plasma membrane 2
cytosol 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for WDR87 Gene

Pathways for WDR87 Gene

SuperPathways for WDR87 Gene

No Data Available

Interacting Proteins for WDR87 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000368025%0d%0a9606.ENSP00000296452%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000368025 for WDR87 Gene via STRING

Gene Ontology (GO) - Biological Process for WDR87 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0009435 NAD biosynthetic process --
genes like me logo Genes that share ontologies with WDR87: view

No data available for Pathways by source for WDR87 Gene

Transcripts for WDR87 Gene

mRNA/cDNA for WDR87 Gene

(5) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for WDR87 Gene

WD repeat domain 87:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for WDR87

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for WDR87
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for WDR87 Gene

No ASD Table

Relevant External Links for WDR87 Gene

GeneLoc Exon Structure for
WDR87
ECgene alternative splicing isoforms for
WDR87

Expression for WDR87 Gene

mRNA expression in normal human tissues for WDR87 Gene

mRNA differential expression in normal tissues according to GTEx for WDR87 Gene

This gene is overexpressed in Testis (46.6).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for WDR87 Gene

SOURCE GeneReport for Unigene cluster for WDR87 Gene Hs.664194

genes like me logo Genes that share expressions with WDR87: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for WDR87 Gene

Orthologs for WDR87 Gene

This gene was present in the common ancestor of chordates.

Orthologs for WDR87 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia WDR87 35
  • 97.97 (n)
  • 96.39 (a)
WDR87 36
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia WDR87 35
  • 78.16 (n)
  • 67.46 (a)
WDR87 36
  • 64 (a)
OneToOne
dog
(Canis familiaris)
Mammalia WDR87 35
  • 77.2 (n)
  • 66.94 (a)
WDR87 36
  • 67 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 4932431P20Rik 36
  • 48 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 39 (a)
OneToMany
-- 36
  • 53 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia WDR87 36
  • 45 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia WDR87 36
  • 34 (a)
OneToOne
Species with no ortholog for WDR87:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for WDR87 Gene

ENSEMBL:
Gene Tree for WDR87 (if available)
TreeFam:
Gene Tree for WDR87 (if available)

Paralogs for WDR87 Gene

Selected SIMAP similar genes for WDR87 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for WDR87 Gene

genes like me logo Genes that share paralogs with WDR87: view

No data available for Paralogs for WDR87 Gene

Variants for WDR87 Gene

Sequence variations from dbSNP and Humsavar for WDR87 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs953370 -- 37,891,688(-) AAGCC(A/G)GCTTT synonymous-codon, reference
rs3894129 -- 37,893,781(+) GAATG(C/G)CTATG missense, reference
rs4803541 -- 37,884,425(+) AGACT(C/T)GTCTG downstream-variant-500B
rs4803542 -- 37,884,650(+) CCCTA(C/G)CTCTG downstream-variant-500B, utr-variant-3-prime
rs4803543 -- 37,884,752(+) GAACC(C/T)GGGAG downstream-variant-500B, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for WDR87 Gene

Variant ID Type Subtype PubMed ID
nsv833820 CNV Loss 17160897

Relevant External Links for WDR87 Gene

HapMap Linkage Disequilibrium report
WDR87

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WDR87 Gene

Disorders for WDR87 Gene

No disorders were found for WDR87 Gene.

No data available for UniProtKB/Swiss-Prot for WDR87 Gene

Publications for WDR87 Gene

  1. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4
  4. Initial characterization of the human central proteome. (PMID: 21269460) Burkard T.R. … Colinge J. (BMC Syst. Biol. 2011) 4

Products for WDR87 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate WDR87
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat
  • Predesigned siRNA for gene silencing in human,mouse,rat for WDR87
  • Block miRNA regulation of WDR87 using miScript Target Protectors

Sources for WDR87 Gene

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