WDR87 Gene
protein-coding GIFtS: 38
GCID: GC19M038376
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WD Repeat Domain 87
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Aliases
for WDR87 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
About This Section
|
| Aliases |
|---|
| WD Repeat Domain 871 2 | | Testis Development Protein NYD-SP112 3 | | NYD-SP112 | | WD Repeat-Containing Protein 872 |
Export aliases for WDR87 gene to outside databasesPrevious GC identifers: GC19M043069 GC19M034824 |
Summaries
for WDR87 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
GeneCards Summary for WDR87 Gene: 
WDR87 (WD repeat domain 87) is a protein-coding gene.
|
Genomic Views
for WDR87 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 73),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NT_011109.16 NC_018930.2
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for WDR87
Other transcription factors
Search SABiosciences Chromatin IP Primers for WDR87
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WDR87 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.13 Ensembl cytogenetic band: 19q13.13 HGNC cytogenetic band: 19q13.13WDR87 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M038376: view genomic region
(about GC identifiers)
Start:
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38,375,463 bp from pter |
End:
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38,397,317 bp from pter |
Size:
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21,855 bases |
Orientation:
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minus strand |
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Proteins
for WDR87 gene
(According to
UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MAXQB
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Ontologies according to Gene
Ontology Consortium 01 Oct 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
About This Section
|
UniProtKB/Swiss-Prot: WDR87_HUMAN, Q6ZQQ6 (See
protein sequence)Recommended Name: WD repeat-containing protein 87 Size: 2873 amino acids; 333185 Da
Sequence caution: Sequence=AAK20167.2; Type=Erroneous termination; Positions=825; Note=Translated as Trp;
Sequence=AAK20167.2; Type=Frameshift; Positions=126, 820, 1129, 1140;
Secondary accessions: Q9BWV9Alternative splicing: 2 isoforms: Q6ZQQ6-1 Q6ZQQ6-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for WDR87: NX_Q6ZQQ6
Explore proteomics data for WDR87 at MOPED
Post-translational modifications:
View modification sites using PhosphoSitePlusView neXtProt modification sites for NX_Q6ZQQ6
WDR87 Protein expression data from MOPED1, PaxDb2 and
MAXQB3 : About this image 
REFSEQ proteins: NP_114157.3
ENSEMBL proteins: ENSP00000405012 ENSP00000368025
Human Recombinant Protein Products for WDR87:
WDR87 Antibody Products:
Assay Products for WDR87: |
Protein
Domains /
Families
for WDR87 gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| HGNC Gene Families:
WDR: WD repeat domain containing
3 InterPro protein domains:Graphical View of Domain Structure for InterPro Entry Q6ZQQ6ProtoNet protein and cluster: Q6ZQQ6 UniProtKB/Swiss-Prot: WDR87_HUMAN, Q6ZQQ6Similarity: Contains 7 WD repeats
WDR87 for domains About GeneDecksing
|
Function
for WDR87 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
genOway,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
Vector BioLabs,
and Sirion Biotech,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene.)
About This Section
|
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004514 | nicotinate-nucleotide diphosphorylase (carboxylating) activity |
-- | -- | | GO:0005488 | binding |
-- | -- | | GO:0005515 | protein binding |
-- | -- |
WDR87 for ontologies About GeneDecksing
Animal Models:
Cell Line
Products: |  | GenScript Custom overexpressing Cell Line Services for WDR87 | |  | Search LifeMap BioReagents cell lines for WDR87 | In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR87 |
Pathways & Interactions
for WDR87 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for WDR87
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0009435 | NAD biosynthetic process |
-- | -- |
WDR87 for ontologies About GeneDecksing
|
Drugs & Compounds
for WDR87 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek,
Ligands according to IUPHAR,
and Drugs according to DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for WDR87
Search CenterWatch for drugs/clinical trials and news about WDR87
|
Transcripts
for WDR87 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Sirion Biotech,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for WDR87 gene: NM_031951.3 Unigene Cluster for WDR87: WD repeat domain 87 Hs.664194 [show with all ESTs]Unigene Representative Sequence: NM_0319513 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000447313(uc010efu.2 uc002ohj.2) ENST00000303868 ENST00000473328
Primer
Products: |  | OriGene qSTAR qPCR primer pairs in human, mouse for WDR87
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat WDR87 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDR87 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR87 |
Additional mRNA sequence: AK128826.1 AK301941.1 AK302913.1 AY026504.2 2 DOTS entries: DT.101970166 DT.91644169 5 AceView cDNA sequences: BX280819 AK128826 AY026504 CD558379 AA629294
GeneLoc Exon Structure
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Expression
for WDR87 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| WDR87 expression in normal human tissues
(normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GCAGAACTGT
About this image
See WDR87 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for WDR87
SOURCE GeneReport for Unigene cluster: Hs.664194
SABiosciences Custom PCR Arrays for WDR87
Primer
Products: | | OriGene qSTAR qPCR primer pairs in human, mouse for WDR87
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat WDR87 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDR87 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR87 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR87 |
Orthologs
for WDR87 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for WDR87 gene from 1/7 species (see all 7) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
WDR876 |
Uncharacterized protein |
34(a) |
1 ↔ 1 |
LGf(2432276-2444180) |
Species with no ortholog for WDR87
ENSEMBL Gene Tree for WDR87 (if available)
TreeFam Gene Tree for WDR87 (if available) |
Paralogs
for WDR87 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for WDR87 gene
1 SIMAP similar gene for WDR87 using alignment to 2 protein entries: WDR87_HUMAN (see all proteins):GNB5
WDR87 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for WDR87
PGOHUM00000234308
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Genomic Variants
for WDR87 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for WDR87 (38375463 - 38397317 bp)
Structural Variations
Database of Genomic Variants (DGV) 1 variation for WDR87: About this table
| | SABiosciences Cancer Mutation PCR Assays |
| | SeqTarget long-range PCR primers for resequencing WDR87 |
|
Disorders
/ Diseases
for WDR87 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for WDR87 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for WDR87 gene integrated from 9 sources:
(articles sorted by number of sources associating them with WDR87) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
|
External Searches for WDR87 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing WDR87 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing WDR87 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing WDR87 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for WDR87 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for WDR87 gene:
Search GeneIP for patents involving WDR87
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for WDR87 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory,
genOway)
About This Section
|
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat WDR87 | | | QIAGEN SeqTarget long-range PCR primers for resequencing WDR87 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WDR87 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat WDR87 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR87 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDR87 |
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 |  |  |  | |
| | | | Search Tocris compounds for WDR87 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR87 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for WDR87 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat WDR87 |
| |  |  |  | | | | LSBio Antibodies in human, mouse, rat for WDR87 |
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