Aliases for WDR87 Gene
Aliases for WDR87 Gene
External Ids for WDR87 Gene
- HGNC: 29934
- Entrez Gene: 83889
- Ensembl: ENSG00000171804
- UniProtKB: Q6ZQQ6
Previous GeneCards Identifiers for WDR87 Gene
- GC19M043069
- GC19M038376
- GC19M034824
Summaries for WDR87 Gene
GeneCards Summary for WDR87 Gene
WDR87 (WD Repeat Domain 87) is a Protein Coding gene. GO annotations related to this gene include binding and nicotinate-nucleotide diphosphorylase (carboxylating) activity.
No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR87 Gene
Genomics for WDR87 Gene
Regulatory Elements for WDR87 Gene
Enhancers for WDR87 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around WDR87 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for WDR87 Gene
- Chromosome:
- 19
- Start:
- 37,884,573 bp from pter
- End:
- 37,906,706 bp from pter
- Size:
- 22,134 bases
- Orientation:
- Minus strand
Genomic View for WDR87 Gene
Genes around WDR87 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.13 by Ensembl
- 19q13.13 by Entrez Gene
- 19q13.13 by HGNC
WDR87 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for WDR87 Gene
Proteins for WDR87 Gene
-
Protein details for WDR87 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6ZQQ6-WDR87_HUMAN
- Recommended name:
- WD repeat-containing protein 87
- Protein Accession:
- Q6ZQQ6
- Q9BWV9
Protein attributes for WDR87 Gene
- Size:
- 2873 amino acids
- Molecular mass:
- 333185 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAK20167.2; Type=Erroneous termination; Positions=825; Note=Translated as Trp.; Evidence={ECO:0000305}; Sequence=AAK20167.2; Type=Frameshift; Positions=126, 820, 1129, 1140; Evidence={ECO:0000305};
Protein Expression for WDR87 Gene
Post-translational modifications for WDR87 Gene
Other Protein References for WDR87 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for WDR87
- Origene Custom Protein Services for WDR87
- Search GeneTex for Proteins for WDR87
Assay Products
No data available for DME Specific Peptides for WDR87 Gene
Domains & Families for WDR87 Gene
Gene Families for WDR87 Gene
Protein Domains for WDR87 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for WDR87 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q6ZQQ6- Similarity:
-
- Contains 7 WD repeats.
Function for WDR87 Gene
Phenotypes for WDR87 Gene
- GenomeRNAi human phenotypes for WDR87:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for WDR87
-
-
ViGene Biosciences lentiviral particle packaged cDNA for WDR87 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for WDR87 gene
- Search ViGene Biosciences for WDR87
CRISPR Products
- Browse CRISPR knockouts for WDR87
- GenScript: Design CRISPR guide RNA sequences for WDR87
miRNA Products
- Search ViGene Biosciences for WDR87
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for WDR87
- Browse OriGene Inhibitory RNA Products For WDR87
-
ViGene Biosciences ready-to-package AAV shRNAs for WDR87 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for WDR87
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for WDR87
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for WDR87
-
ViGene Biosciences adenoviral particle packaged cDNA for WDR87 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for WDR87 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for WDR87 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for WDR87 Gene
Localization for WDR87 Gene
| Compartment | Confidence |
|---|---|
| plasma membrane | 2 |
| nucleus | 2 |
| peroxisome | 1 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IBA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for WDR87 Gene
Pathways & Interactions for WDR87 Gene
No Data Available
Interacting Proteins for WDR87 Gene
No data available for Pathways by source and SIGNOR curated interactions for WDR87 Gene
Transcripts for WDR87 Gene
mRNA/cDNA for WDR87 Gene
- (3) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (5) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for WDR87
- GenScript: Design CRISPR guide RNA sequences for WDR87
miRNA Products
- Search ViGene Biosciences for WDR87
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for WDR87
- Browse OriGene Inhibitory RNA Products For WDR87
-
ViGene Biosciences ready-to-package AAV shRNAs for WDR87 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for WDR87
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for WDR87
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for WDR87 Gene
mRNA differential expression in normal tissues according to GTEx for WDR87 Gene
This gene is overexpressed in Testis (x46.6).
This gene is overexpressed in Liver (25.3), Synovial fluid (12.4), and Platelet (10.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for WDR87 Gene
NURSA nuclear receptor signaling pathways regulating expression of WDR87 Gene:
WDR87SOURCE GeneReport for Unigene cluster for WDR87 Gene:
Hs.664194Primer Products
-
OriGene qPCR primer pairs for WDR87
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for WDR87 Gene
Orthologs for WDR87 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | WDR87 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | WDR87 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | WDR87 34 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| mouse (Mus musculus) |
Mammalia | 4932431P20Rik 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | WDR87 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | WDR87 35 |
|
OneToOne |
- Species where no ortholog for WDR87 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for WDR87 Gene
(1) SIMAP similar genes for WDR87 Gene using alignment to 2 proteins:
Pseudogenes.org Pseudogenes for WDR87 Gene
No data available for Paralogs for WDR87 Gene
Variants for WDR87 Gene
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs10404567 | -- | 37,906,573(+) | CAACT(A/G)AGAAG | intron-variant, upstream-variant-2KB, utr-variant-5-prime | |
| rs10408510 | -- | 37,885,845(+) | CTTCA(A/T)GTTTG | intron-variant, reference, missense | |
| rs10422056 | -- | 37,887,899(+) | ATCTT(C/G)TTGAA | intron-variant, reference, missense | |
| rs10618499 | -- | 37,902,050(+) | TATTT(-/ATTTATTT)GCCAC | intron-variant | |
| rs10676914 | -- | 37,905,467(+) | AGTAA(-/GTAA)ATAAT | intron-variant, upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3390200 | CNV | insertion | 20981092 |
| esv3583378 | CNV | loss | 25503493 |
| nsv1064401 | CNV | loss | 25217958 |
| nsv833820 | CNV | loss | 17160897 |
Gene Damage Index Score:
9.02;
87.46% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for WDR87 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WDR87 Gene
Disorders for WDR87 Gene
Relevant External Links for WDR87
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- WDR87
No disorders were found for WDR87 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for WDR87 Gene
Publications for WDR87 Gene
- Initial characterization of the human central proteome. (PMID: 21269460) Burkard T.R. … Colinge J. (BMC Syst. Biol. 2011) 4 64
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 64
- The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4 64
Products for WDR87 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for WDR87
- Origene Custom Protein Services for WDR87
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for WDR87
- Browse OriGene Inhibitory RNA Products For WDR87
- OriGene qPCR primer pairs for WDR87
- Browse CRISPR knockouts for WDR87
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For WDR87
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for WDR87
- GenScript Custom Assay Services for WDR87
- GenScript Custom overexpressing Cell Line Services for WDR87
- GenScript: Design CRISPR guide RNA sequences for WDR87
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for WDR87
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for WDR87
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for WDR87 gene
- ViGene Biosciences lentiviral particle packaged cDNA for WDR87 gene
- ViGene Biosciences ready-to-package AAV shRNAs for WDR87 gene
- Search ViGene Biosciences for WDR87
- Horizon Cell Lines for WDR87
- Cyagen custom Knockout/knockin (KOKI) mouse models for WDR87
- VectorBuilder custom plasmid, inducible vectors for WDR87
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for WDR87
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for WDR87 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab