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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

WDR83 Gene

protein-coding   GIFtS: 51
GCID: GC19P012777

WD Repeat Domain 83

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
WD Repeat Domain 831 2
MAPK Organizer 11 2 3
Mitogen-Activated Protein Kinase Organizer 12 3
MORG12 3
WD Repeat Domain-Containing Protein 832

External Ids:    HGNC: 326721   Entrez Gene: 842922   Ensembl: ENSG000001231547   UniProtKB: Q9BRX93   
ORGUL members:         
NONCODE14:n408315      

Export aliases for WDR83 gene to outside databases

Previous GC identifer: GC19P012350


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for WDR83 Gene:
This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular
scaffold for various multimeric protein complexes. The protein associates with several components of the
extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other
signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression
of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in
multiple transcript variants. (provided by RefSeq, Oct 2009)

GeneCards Summary for WDR83 Gene: 
WDR83 (WD repeat domain 83) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with WDR83 include hypoxia, and intrahepatic cholangiocarcinoma. An important paralog of this gene is POC1B.

UniProtKB/Swiss-Prot: WDR83_HUMAN, Q9BRX9
Function: Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of
a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations
it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved
in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with
EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream
activator (By similarity). May also be involved in pre-mRNA splicing




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.2  NT_011295.11  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for WDR83
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): WDR83 promoter sequence
   Search SABiosciences Chromatin IP Primers for WDR83

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WDR83


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.2   Ensembl cytogenetic band:  19p13.2   HGNC cytogenetic band: 19p13.13

WDR83 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WDR83 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P012777:  view genomic region     (about GC identifiers)

Start:
12,777,614 bp from pter      End:
12,786,646 bp from pter
Size:
9,033 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: WDR83_HUMAN, Q9BRX9 (See protein sequence)
Recommended Name: WD repeat domain-containing protein 83  
Size: 315 amino acids; 34343 Da
Subunit: Interacts with EGLN3/PHD3. Interacts with ERK signaling proteins MAP2K1/MEK1, MAP2K2/MEK2, LAMTOR3,
ARAF/Raf-1, MAPK1/ERK2 and MAPK3/ERK1 (By similarity). Identified in the spliceosome C complex
Subcellular location: Cytoplasm (By similarity). Nucleus (By similarity). Note=Predominantly cytoplasmic (By
similarity). Partially nuclear (By similarity)
Secondary accessions: B2RAF1 Q53FT6

Explore the universe of human proteins at neXtProt for WDR83: NX_Q9BRX9

Explore proteomics data for WDR83 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BRX9

  • WDR83 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    WDR83 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001093207.1  NP_115708.1  

    ENSEMBL proteins: 
     ENSP00000402653   ENSP00000448722   ENSP00000450416   ENSP00000448331   ENSP00000396530  
     ENSP00000449257   ENSP00000242796  

    Human Recombinant Protein Products for WDR83: 
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    Novus Biologicals WDR83 Proteins
    Novus Biologicals WDR83 Lysates
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    Cloud-Clone Corp. Proteins for WDR83 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005681spliceosomal complex IDA11991638
    GO:0005737cytoplasm IEA--
    GO:0071013catalytic step 2 spliceosome IDA11991638

    WDR83 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    WDR: WD repeat domain containing

    5 InterPro protein domains:
     IPR019775 WD40_repeat_CS
     IPR001680 WD40_repeat
     IPR020472 G-protein_beta_WD-40_rep
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q9BRX9

    ProtoNet protein and cluster: Q9BRX9

    UniProtKB/Swiss-Prot: WDR83_HUMAN, Q9BRX9
    Similarity: Belongs to the WD repeat MORG1 family
    Similarity: Contains 7 WD repeats


    WDR83 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: WDR83_HUMAN, Q9BRX9
    Function: Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of
    a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations
    it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved
    in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with
    EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream
    activator (By similarity). May also be involved in pre-mRNA splicing

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0016301kinase activity ----
         
    WDR83 for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for WDR83:
     Decreased influenza A H1N1 (A/  Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r  Synthetic lethal with Ras 

         7 MGI mutant phenotypes (inferred from 1 allele(MGI details for Wdr83):
     cardiovascular system  cellular  embryogenesis  homeostasis/metabolism  immune system 
     mortality/aging  renal/urinary system 

    WDR83 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for WDR83 
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for WDR83

    STRING Interaction Network Preview (showing 5 interactants - click image to see 21)

    5/21 Interacting proteins for WDR83 (Q9BRX92, 3 ENSP000002427964) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBL5Q9BZL12, ENSP000003514924MINT-8337629 MINT-8332108 STRING: ENSP00000351492
    SF3B4Q154272, ENSP000002716284MINT-8333878 MINT-8332086 STRING: ENSP00000271628
    SNRPCP092342, ENSP000002445204MINT-8332075 MINT-8333031 STRING: ENSP00000244520
    PPIL1Q9Y3C62, ENSP000003628034MINT-8332097 MINT-8337189 STRING: ENSP00000362803
    PRPF8Q6P2Q92, ENSP000003043504MINT-8331844 MINT-8336012 STRING: ENSP00000304350
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000375RNA splicing, via transesterification reactions IDA11991638
    GO:0000398mRNA splicing, via spliceosome IDA11991638

    WDR83 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for WDR83

    Search CenterWatch for drugs/clinical trials and news about WDR83

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for WDR83 gene (2 alternative transcripts): 
    NM_001099737.2  NM_032332.3  

    Unigene Cluster for WDR83:

    WD repeat domain 83
    Hs.657204  [show with all ESTs]
    Unigene Representative Sequence: NM_001099737
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000418543(uc002muc.3 uc002mue.4) ENST00000546754 ENST00000548381
    ENST00000553179 ENST00000547255 ENST00000547481 ENST00000550939 ENST00000551329
    ENST00000425834 ENST00000547797 ENST00000552700 ENST00000242796(uc010dyw.3)

    miRNA
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    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDR83
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR83

    Additional mRNA sequence: 

    AK074525.1 AK223195.1 AK314164.1 BC005870.2 NR_029375.1 

    17 DOTS entries:

    DT.75109309  DT.95224094  DT.75176677  DT.95154416  DT.100637802  DT.120292  DT.100868758  DT.100868748 
    DT.121449444  DT.100868753  DT.100868764  DT.121449270  DT.100038902  DT.100038909  DT.100735195  DT.446116 
    DT.92445179 

    24/96 AceView cDNA sequences (see all 96):

    BF981501 CB127193 CA413967 BQ446577 CD518475 BM726317 BM561618 BU195425 
    BI857453 BU633655 Z41813 AK074525 BU738580 BU557788 AI864001 AI206616 
    CB143206 BE887549 BQ941919 BQ056907 BQ951078 BM746075 NM_032332 CR602746 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for WDR83    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8
    SP1:                                                      
    SP2:                          -     -                     


    ECgene alternative splicing isoforms for WDR83

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    WDR83 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAAGGACTTC
    WDR83 Expression
    About this image


    See WDR83 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for WDR83

    SOURCE GeneReport for Unigene cluster: Hs.657204
        SABiosciences Custom PCR Arrays for WDR83
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for WDR83 gene from 9/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Wdr831 , 5 WD repeat domain containing 831, 5 88.04(n)1
    93.97(a)1
      8 (41.55 cM)5
    678361  NM_026399.21  NP_080675.21 
     850750355 
    lizard
    (Anolis carolinensis)
    Reptilia WDR836
    Uncharacterized protein
    80(a)
    1 ↔ 1
    GL343286.1(744860-751066)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.28572 Transcribed sequence with moderate similarity to protein more 75.84(n)    BX709389.1 
    zebrafish
    (Danio rerio)
    Actinopterygii 570740112   -- 74.25(n)    57074011 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG49351 CG4935 52.63(n)
    48.42(a)
      34955  NM_135938.2  NP_609782.2 
    worm
    (Caenorhabditis elegans)
    Secernentea F33G12.21 Protein F33G12.2 49.49(n)
    48.46(a)
      173867  NM_062525.3  NP_494926.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes TAF56
    Subunit (90 kDa) of TFIID and SAGA complexes, invo...
    8(a)
    1 → many
    II(616127-618523)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G647301 transducin/WD40 domain-containing protein 52.15(n)
    51.36(a)
      836594  NM_125869.2  NP_568993.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g05434001 hypothetical protein 56.13(n)
    49.83(a)
      4329605  NM_001053610.1  NP_001047075.1 


    ENSEMBL Gene Tree for WDR83 (if available)
    TreeFam Gene Tree for WDR83 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for WDR83 gene
    POC1B2  WDR52  WDR482  ATG16L12  SNRNP402  WDR5B2  PAFAH1B12  SMU12  
    DAW12  PRPF42  WDR382  ATG16L22  POC1A2  
    18/28 SIMAP similar genes for WDR83 using alignment to 5 protein entries:     WDR83_HUMAN (see all proteins) (see all similar genes):
    NARF    TBL1X    WDR31    TBL1Y    WSB1    WSB2
    KATNB1    TBL1XR1    GNB2L1    BRWD1    WDR38    WDR9
    GNB5    SNRNP40    LOC349136    WDR86    WDR5B    DAW1

    WDR83 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/268 SNPs in WDR83 are shown (see all 268)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1482732501,2
    --12352768(+) CCTGCC/TCTTTT 3 -- us2k1 int10--------
    rs1163957131,2
    F--12352791(+) CTCCAA/GGTTGC 3 -- us2k1 int11Minor allele frequency- G:0.01WA 118
    rs1413854491,2
    C--12352860(+) CTTGAC/TTTCAC 3 -- us2k1 int10--------
    rs1439464751,2
    C--12352948(+) TGACA-/AGAC  
            
    ACCCC
    3 -- us2k1 int10--------
    rs1813248301,2
    C--12352994(+) CTCAGC/GTCCAA 3 -- us2k1 int10--------
    rs2020781471,2
    --12353071(+) CAGCAA/GGTTCA 3 -- us2k1 int10--------
    rs617483461,2
    C,F--12353101(+) GTCCAA/GGGCCG 3 -- us2k1 int14Minor allele frequency- G:0.01NS CSA NA EU 5789
    rs1863279561,2
    C--12353105(+) AAGGCC/TGGGTT 3 -- us2k1 int10--------
    rs2011796041,2
    --12353231(+) AACCCA/GTGCCC 3 -- us2k1 int10--------
    rs1915905511,2
    --12353242(+) ACGACA/GCTGGG 3 -- us2k1 int10--------

    HapMap Linkage Disequilibrium report for WDR83 (12777614 - 12786646 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for WDR83:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv3733n71CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    4 diseases for WDR83:    About MalaCards
    hypoxia    intrahepatic cholangiocarcinoma    cholangiocarcinoma    gastric cancer


    WDR83 for disorders           About GeneDecksing


    Export disorders for WDR83 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for WDR83 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with WDR83)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Modular construction of a signaling scaffold: MORG1 interacts with components of the ERK cascade and links ERK signaling to specific agonists. (PubMed id 15118098)1, 3, 9 Vomastek T....Weber M.J. (2004)
    2. The novel WD-repeat protein Morg1 acts as a molecular scaffold for hypoxia-inducible factor prolyl hydroxylase 3 (PHD3). (PubMed id 16407229)1, 3 Hopfer U....Wolf G. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. (PubMed id 11991638)1, 2 Jurica M.S.... Moore M.J. (2002)
    5. The WD40 protein Morg1 facilitates Par6-aPKC binding t o Crb3 for apical identity in epithelial cells. (PubMed id 23439680)1 Hayase J....Sumimoto H. (2013)
    6. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (2013)
    7. Dynamic protein-protein interaction wiring of the huma n spliceosome. (PubMed id 22365833)1 Hegele A....Stelzl U. (2012)
    8. Bidirectional regulation between WDR83 and its natural antisense transcript DHPS in gastric cancer. (PubMed id 22491477)1 Su W.Y....Fang J.Y. (2012)
    9. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    10. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84292 HGNC: 32672 AceView: MGC4238 Ensembl:ENSG00000123154 euGenes: HUgn84292
    ECgene: WDR83 H-InvDB: WDR83

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for WDR83 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for WDR83 gene:
    Search GeneIP for patents involving WDR83

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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