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Aliases for WDR64 Gene

Aliases for WDR64 Gene

  • WD Repeat Domain 64 2 3

External Ids for WDR64 Gene

Previous GeneCards Identifiers for WDR64 Gene

  • GC01P238173
  • GC01P239882
  • GC01P241815
  • GC01P212273

Summaries for WDR64 Gene

GeneCards Summary for WDR64 Gene

WDR64 (WD Repeat Domain 64) is a Protein Coding gene. An important paralog of this gene is EFCAB8.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR64 Gene

Genomics for WDR64 Gene

Regulatory Elements for WDR64 Gene

Genomic Location for WDR64 Gene

241,652,278 bp from pter
241,802,745 bp from pter
150,468 bases
Plus strand

Genomic View for WDR64 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for WDR64 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WDR64 Gene

Proteins for WDR64 Gene

  • Protein details for WDR64 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    WD repeat-containing protein 64
    Protein Accession:
    Secondary Accessions:
    • B1ANT0
    • Q7Z573
    • Q96LY9

    Protein attributes for WDR64 Gene

    1081 amino acids
    Molecular mass:
    123631 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAP92796.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAB71525.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for WDR64 Gene


neXtProt entry for WDR64 Gene

Proteomics data for WDR64 Gene at MOPED

Post-translational modifications for WDR64 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for WDR64 Gene

No data available for DME Specific Peptides for WDR64 Gene

Domains & Families for WDR64 Gene

Gene Families for WDR64 Gene

Protein Domains for WDR64 Gene

Suggested Antigen Peptide Sequences for WDR64 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 14 WD repeats.
  • Contains 14 WD repeats.
genes like me logo Genes that share domains with WDR64: view

Function for WDR64 Gene

Gene Ontology (GO) - Molecular Function for WDR64 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with WDR64: view

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for WDR64

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for WDR64 Gene

Localization for WDR64 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for WDR64 Gene

Pathways & Interactions for WDR64 Gene

SuperPathways for WDR64 Gene

No Data Available

Interacting Proteins for WDR64 Gene

Gene Ontology (GO) - Biological Process for WDR64 Gene


No data available for Pathways by source and SIGNOR curated interactions for WDR64 Gene

Drugs & Compounds for WDR64 Gene

No Compound Related Data Available

Transcripts for WDR64 Gene

mRNA/cDNA for WDR64 Gene

(12) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(13) Selected AceView cDNA sequences:
(8) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for WDR64 Gene

WD repeat domain 64:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for WDR64

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for WDR64 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22
SP1: -
SP2: - - - - - -

Relevant External Links for WDR64 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for WDR64 Gene

mRNA expression in normal human tissues for WDR64 Gene

mRNA differential expression in normal tissues according to GTEx for WDR64 Gene

This gene is overexpressed in Testis (x35.8).

Protein differential expression in normal tissues from HIPED for WDR64 Gene

This gene is overexpressed in Lymph node (24.5), Plasma (8.8), and Fetal gut (6.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for WDR64 Gene

SOURCE GeneReport for Unigene cluster for WDR64 Gene Hs.97527

genes like me logo Genes that share expression patterns with WDR64: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for WDR64 Gene

Orthologs for WDR64 Gene

This gene was present in the common ancestor of animals.

Orthologs for WDR64 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia WDR64 35
  • 87.84 (n)
  • 85.37 (a)
WDR64 36
  • 83 (a)
(Canis familiaris)
Mammalia WDR64 35
  • 87.33 (n)
  • 84.55 (a)
-- 36
  • 79 (a)
-- 36
  • 81 (a)
(Mus musculus)
Mammalia Wdr64 35
  • 81.89 (n)
  • 80.8 (a)
Wdr64 16
Wdr64 36
  • 78 (a)
(Pan troglodytes)
Mammalia WDR64 35
  • 99.2 (n)
  • 98.98 (a)
WDR64 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Wdr64 35
  • 81.68 (n)
  • 80.41 (a)
(Monodelphis domestica)
Mammalia WDR64 36
  • 65 (a)
(Ornithorhynchus anatinus)
Mammalia WDR64 36
  • 18 (a)
(Gallus gallus)
Aves WDR64 35
  • 62.66 (n)
  • 51.26 (a)
WDR64 36
  • 48 (a)
(Anolis carolinensis)
Reptilia WDR64 36
  • 53 (a)
(Danio rerio)
Actinopterygii si:dkey-1m11.8 36
  • 17 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG40583 36
  • 21 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 20 (a)
Species with no ortholog for WDR64:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for WDR64 Gene

Gene Tree for WDR64 (if available)
Gene Tree for WDR64 (if available)

Paralogs for WDR64 Gene

Paralogs for WDR64 Gene

genes like me logo Genes that share paralogs with WDR64: view

Variants for WDR64 Gene

Sequence variations from dbSNP and Humsavar for WDR64 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs951098 -- 241,797,188(-) TAAGA(C/G)AGTCT intron-variant
rs952084 -- 241,782,992(-) TCATT(C/T)AATTG intron-variant
rs953597 -- 241,783,464(-) TGAAC(G/T)ATATA intron-variant
rs1342866 -- 241,797,367(+) AAGCT(C/T)TCAGG intron-variant
rs1342867 -- 241,800,414(+) AACAT(A/T)ACTGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for WDR64 Gene

Variant ID Type Subtype PubMed ID
nsv873368 CNV Gain 21882294
nsv873372 CNV Gain 21882294
esv2726240 CNV Deletion 23290073
esv2661246 CNV Deletion 23128226
nsv528015 CNV Gain 19592680
esv2726252 CNV Deletion 23290073
esv2624301 CNV Insertion 19546169
esv271922 CNV Insertion 20981092
esv2673784 CNV Deletion 23128226
nsv873373 CNV Gain 21882294

Variation tolerance for WDR64 Gene

Gene Damage Index Score: 9.09; 87.68% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for WDR64 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WDR64 Gene

Disorders for WDR64 Gene

Relevant External Links for WDR64

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with WDR64: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for WDR64 Gene

Publications for WDR64 Gene

  1. A genome-wide association study of behavioral disinhibition. (PMID: 23942779) McGue M. … Iacono W.G. (Behav. Genet. 2013) 67
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 67
  3. Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines. (PMID: 20923822) Niu N. … Wang L. (Genome Res. 2010) 67
  4. Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis. (PMID: 19626040) McCauley J.L. … Haines J.L. (Genes Immun. 2009) 67
  5. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 67

Products for WDR64 Gene

Sources for WDR64 Gene

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