Aliases for WDR64 Gene
External Ids for WDR64 Gene
- HGNC: 26570
- Entrez Gene: 128025
- Ensembl: ENSG00000162843
- UniProtKB: B1ANS9
Previous GeneCards Identifiers for WDR64 Gene
- GC01P238173
- GC01P239882
- GC01P241815
- GC01P212273
Summaries for WDR64 Gene
GeneCards Summary for WDR64 Gene
WDR64 (WD Repeat Domain 64) is a Protein Coding gene. An important paralog of this gene is EFCAB8.
No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR64 Gene
Genomics for WDR64 Gene
Regulatory Elements for WDR64 Gene
Enhancers for WDR64 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around WDR64 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the WDR64 gene promoter:
Regulatory Element Products
Genomic Location for WDR64 Gene
- Chromosome:
- 1
- Start:
- 241,652,278 bp from pter
- End:
- 241,802,745 bp from pter
- Size:
- 150,468 bases
- Orientation:
- Plus strand
Genomic View for WDR64 Gene
Genes around WDR64 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q43 by Ensembl
- 1q43 by Entrez Gene
- 1q43 by HGNC
WDR64 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for WDR64 Gene
Proteins for WDR64 Gene
-
Protein details for WDR64 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- B1ANS9-WDR64_HUMAN
- Recommended name:
- WD repeat-containing protein 64
- Protein Accession:
- B1ANS9
- B1ANT0
- Q7Z573
- Q96LY9
Protein attributes for WDR64 Gene
- Size:
- 1081 amino acids
- Molecular mass:
- 123631 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAP92796.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAB71525.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for WDR64 Gene
Post-translational modifications for WDR64 Gene
Other Protein References for WDR64 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for WDR64
- Abcam antibodies for WDR64
- Search GeneTex for Antibodies for WDR64
-
Santa Cruz Biotechnology (SCBT) Antibodies for WDR64
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for WDR64
- Origene Custom Protein Services for WDR64
- Novus Biologicals proteins for WDR64
- Search GeneTex for Proteins for WDR64
Assay Products
No data available for DME Specific Peptides for WDR64 Gene
Domains & Families for WDR64 Gene
Gene Families for WDR64 Gene
Protein Domains for WDR64 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for WDR64 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
B1ANS9- Similarity:
-
- Contains 14 WD repeats.
Function for WDR64 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for WDR64 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for WDR64 gene
- Search ViGene Biosciences for WDR64
miRNA Products
- Search ViGene Biosciences for WDR64
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for WDR64
- Browse OriGene Inhibitory RNA Products For WDR64
-
ViGene Biosciences ready-to-package AAV shRNAs for WDR64 gene
Clone Products
- OriGene clones in human for WDR64
- OriGene ORF clones in human,mouse for WDR64
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for WDR64 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for WDR64 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for WDR64 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for WDR64 Gene
Localization for WDR64 Gene
| Compartment | Confidence |
|---|---|
| cytosol | 2 |
| nucleus | 2 |
| mitochondrion | 1 |
| peroxisome | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for WDR64 Gene
Pathways & Interactions for WDR64 Gene
More details on SuperPathways for WDR64
No Data Available
Interacting Proteins for WDR64 Gene
No data available for Pathways by source and SIGNOR curated interactions for WDR64 Gene
Transcripts for WDR64 Gene
mRNA/cDNA for WDR64 Gene
- (12) REFSEQ mRNAs :
- (3) Additional mRNA sequences :
- (13) Selected AceView cDNA sequences:
- (8) Ensembl transcripts including schematic representations, and UCSC links where relevant :
miRNA Products
- Search ViGene Biosciences for WDR64
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for WDR64
- Browse OriGene Inhibitory RNA Products For WDR64
-
ViGene Biosciences ready-to-package AAV shRNAs for WDR64 gene
Clone Products
- OriGene clones in human for WDR64
- OriGene ORF clones in human,mouse for WDR64
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - |
Expression for WDR64 Gene
mRNA differential expression in normal tissues according to GTEx for WDR64 Gene
This gene is overexpressed in Testis (x35.8).
This gene is overexpressed in Lymph node (24.5), Plasma (8.8), and Fetal gut (6.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for WDR64 Gene
SOURCE GeneReport for Unigene cluster for WDR64 Gene Hs.97527
Primer Products
-
OriGene qPCR primer pairs for WDR64
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for WDR64 Gene
Orthologs for WDR64 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | WDR64 35 |
|
||
| WDR64 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | WDR64 35 |
|
||
| -- 36 |
|
OneToMany | |||
| -- 36 |
|
OneToMany | |||
| mouse (Mus musculus) |
Mammalia | Wdr64 35 |
|
||
| Wdr64 16 |
|
||||
| Wdr64 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | WDR64 35 |
|
||
| WDR64 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Wdr64 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | WDR64 36 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | WDR64 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | WDR64 35 |
|
||
| WDR64 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | WDR64 36 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | si:dkey-1m11.8 36 |
|
ManyToMany | |
| fruit fly (Drosophila melanogaster) |
Insecta | CG40583 36 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 36 |
|
ManyToMany |
- Species with no ortholog for WDR64:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for WDR64 Gene
Variants for WDR64 Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs12095445 | - | 241,766,240(+) | ATTAC(A/G)AGTGA | reference, missense | |
| rs12074374 | - | 241,788,027(+) | TTGAC(C/T)GGGAA | downstream-variant-500B, reference, missense | |
| rs951098 | -- | 241,797,188(-) | TAAGA(C/G)AGTCT | intron-variant | |
| rs952084 | -- | 241,782,992(-) | TCATT(C/T)AATTG | intron-variant | |
| rs953597 | -- | 241,783,464(-) | TGAAC(G/T)ATATA | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv873368 | CNV | Gain | 21882294 |
| nsv873372 | CNV | Gain | 21882294 |
| esv2726240 | CNV | Deletion | 23290073 |
| esv2661246 | CNV | Deletion | 23128226 |
| nsv528015 | CNV | Gain | 19592680 |
| esv2726252 | CNV | Deletion | 23290073 |
| esv2624301 | CNV | Insertion | 19546169 |
| esv271922 | CNV | Insertion | 20981092 |
| esv2673784 | CNV | Deletion | 23128226 |
| nsv873373 | CNV | Gain | 21882294 |
Gene Damage Index Score:
9.09;
87.68% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for WDR64 Gene
- Human Gene Mutation Database (HGMD)
- WDR64
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WDR64 Gene
Disorders for WDR64 Gene
Relevant External Links for WDR64
No disorders were found for WDR64 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for WDR64 Gene
Publications for WDR64 Gene
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48 67
- A genome-wide association study of behavioral disinhibition. (PMID: 23942779) McGue M. … Iacono W.G. (Behav. Genet. 2013) 3
- Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines. (PMID: 20923822) Niu N. … Wang L. (Genome Res. 2010) 3
- Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis. (PMID: 19626040) McCauley J.L. … Haines J.L. (Genes Immun. 2009) 3
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
Products for WDR64 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for WDR64
- Origene Custom Protein Services for WDR64
- Origene siRNA, shRNA, and RNAi products in human, mouse, rat for WDR64
- Browse OriGene Inhibitory RNA Products For WDR64
- OriGene qPCR primer pairs for WDR64
- OriGene CRISPR knockouts for WDR64
- OriGene clones in human for WDR64
- OriGene ORF clones in human,mouse for WDR64
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for WDR64
- GenScript Custom Assay Services for WDR64
- GenScript Custom overexpressing Cell Line Services for WDR64
- Browse GenScript CRISPR for WDR64
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for WDR64
- Novus Biologicals Antibodies for WDR64
- Novus Biologicals proteins for WDR64
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ViGene Biosciences adenoviral particle packaged cDNA for WDR64 gene
- ViGene Biosciences lentiviral particle packaged cDNA for WDR64 gene
- ViGene Biosciences lentiviral particle packaged cDNA for WDR64 gene
- ViGene Biosciences ready-to-package AAV shRNAs for WDR64 gene
- ViGene Biosciences ready-to-package AAV shRNAs for WDR64 gene
- ViGene Biosciences ready-to-package AAV shRNAs for WDR64 gene
- Search ViGene Biosciences for WDR64
- Search ViGene Biosciences for WDR64
- Santa Cruz Biotechnology (SCBT) Antibodies for WDR64
- Search Santa Cruz Biotechnology (SCBT) for WDR64 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for WDR64
Sources for WDR64 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon