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Aliases for WDR64 Gene

Aliases for WDR64 Gene

  • WD Repeat Domain 64 2 3

External Ids for WDR64 Gene

Summaries for WDR64 Gene

GeneCards Summary for WDR64 Gene

WDR64 (WD Repeat Domain 64) is a Protein Coding gene. An important paralog of this gene is EFCAB8.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR64 Gene

Genomics for WDR64 Gene

Genomic Location for WDR64 Gene

Start:
241,652,278 bp from pter
End:
241,802,133 bp from pter
Size:
149,856 bases
Orientation:
Plus strand

Genomic View for WDR64 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for WDR64 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WDR64 Gene

Regulatory Elements for WDR64 Gene

Proteins for WDR64 Gene

  • Protein details for WDR64 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B1ANS9-WDR64_HUMAN
    Recommended name:
    WD repeat-containing protein 64
    Protein Accession:
    B1ANS9
    Secondary Accessions:
    • B1ANT0
    • Q7Z573
    • Q96LY9

    Protein attributes for WDR64 Gene

    Size:
    1081 amino acids
    Molecular mass:
    123631 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAP92796.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAB71525.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for WDR64 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for WDR64 Gene

Proteomics data for WDR64 Gene at MOPED

Post-translational modifications for WDR64 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for WDR64 Gene

No data available for DME Specific Peptides for WDR64 Gene

Domains for WDR64 Gene

Gene Families for WDR64 Gene

HGNC:
  • WDR :WD repeat domain containing

Protein Domains for WDR64 Gene

Suggested Antigen Peptide Sequences for WDR64 Gene

Graphical View of Domain Structure for InterPro Entry

B1ANS9

UniProtKB/Swiss-Prot:

WDR64_HUMAN
Similarity:
  • Contains 14 WD repeats.:
    • B1ANS9
genes like me logo Genes that share domains with WDR64: view

Function for WDR64 Gene

Gene Ontology (GO) - Molecular Function for WDR64 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with WDR64: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for WDR64 Gene

Localization for WDR64 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for WDR64 Gene COMPARTMENTS Subcellular localization image for WDR64 gene
Compartment Confidence
cytosol 2
nucleus 2
mitochondrion 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for WDR64 Gene

Pathways for WDR64 Gene

SuperPathways for WDR64 Gene

No Data Available

Interacting Proteins for WDR64 Gene

Gene Ontology (GO) - Biological Process for WDR64 Gene

None

No data available for Pathways by source for WDR64 Gene

Transcripts for WDR64 Gene

mRNA/cDNA for WDR64 Gene

(12) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(13) Selected AceView cDNA sequences:
(8) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for WDR64 Gene

WD repeat domain 64:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for WDR64 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22
SP1: -
SP2: - - - - - -

Relevant External Links for WDR64 Gene

GeneLoc Exon Structure for
WDR64
ECgene alternative splicing isoforms for
WDR64

Expression for WDR64 Gene

mRNA expression in normal human tissues for WDR64 Gene

mRNA differential expression in normal tissues according to GTEx for WDR64 Gene

This gene is overexpressed in Testis (35.8).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for WDR64 Gene

SOURCE GeneReport for Unigene cluster for WDR64 Gene Hs.97527

genes like me logo Genes that share expressions with WDR64: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for WDR64 Gene

Orthologs for WDR64 Gene

This gene was present in the common ancestor of animals.

Orthologs for WDR64 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia WDR64 35
  • 99.2 (n)
  • 98.98 (a)
WDR64 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia WDR64 35
  • 87.84 (n)
  • 85.37 (a)
WDR64 36
  • 83 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 36
  • 79 (a)
OneToMany
-- 36
  • 81 (a)
OneToMany
WDR64 35
  • 87.33 (n)
  • 84.55 (a)
mouse
(Mus musculus)
Mammalia Wdr64 35
  • 81.89 (n)
  • 80.8 (a)
Wdr64 16
Wdr64 36
  • 78 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia WDR64 36
  • 65 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia WDR64 36
  • 18 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Wdr64 35
  • 81.68 (n)
  • 80.41 (a)
chicken
(Gallus gallus)
Aves WDR64 35
  • 62.66 (n)
  • 51.26 (a)
WDR64 36
  • 48 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia WDR64 36
  • 53 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii si:dkey-1m11.8 36
  • 17 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta CG40583 36
  • 21 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 20 (a)
ManyToMany
Species with no ortholog for WDR64:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for WDR64 Gene

ENSEMBL:
Gene Tree for WDR64 (if available)
TreeFam:
Gene Tree for WDR64 (if available)

Paralogs for WDR64 Gene

Paralogs for WDR64 Gene

genes like me logo Genes that share paralogs with WDR64: view

Variants for WDR64 Gene

Sequence variations from dbSNP and Humsavar for WDR64 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs951098 -- 241,797,188(-) TAAGA(C/G)AGTCT intron-variant
rs952084 -- 241,782,992(-) TCATT(C/T)AATTG intron-variant
rs953597 -- 241,783,464(-) TGAAC(G/T)ATATA intron-variant
rs1342866 -- 241,797,367(+) AAGCT(C/T)TCAGG intron-variant
rs1342867 -- 241,800,414(+) AACAT(A/T)ACTGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for WDR64 Gene

Variant ID Type Subtype PubMed ID
nsv873368 CNV Gain 21882294
nsv873372 CNV Gain 21882294
esv2726240 CNV Deletion 23290073
esv2661246 CNV Deletion 23128226
nsv528015 CNV Gain 19592680
esv2726252 CNV Deletion 23290073
esv2624301 CNV Insertion 19546169
esv271922 CNV Insertion 20981092
esv2673784 CNV Deletion 23128226
nsv873373 CNV Gain 21882294

Relevant External Links for WDR64 Gene

HapMap Linkage Disequilibrium report
WDR64
Human Gene Mutation Database (HGMD)
WDR64

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WDR64 Gene

Disorders for WDR64 Gene

Relevant External Links for WDR64

Genetic Association Database (GAD)
WDR64
Human Genome Epidemiology (HuGE) Navigator
WDR64
genes like me logo Genes that share disorders with WDR64: view

No data available for UniProtKB/Swiss-Prot for WDR64 Gene

Publications for WDR64 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis. (PMID: 19626040) McCauley J.L. … Haines J.L. (Genes Immun. 2009) 3 48
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  4. Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines. (PMID: 20923822) Niu N. … Wang L. (Genome Res. 2010) 3 48
  5. A genome-wide association study of behavioral disinhibition. (PMID: 23942779) McGue M. … Iacono W.G. (Behav. Genet. 2013) 3

Products for WDR64 Gene

Sources for WDR64 Gene

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