WDR64 Gene
protein-coding GIFtS: 40
GCID: GC01P241815
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WD repeat domain 64
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Aliases
for WDR64 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| WD Repeat Domain 641 2 | | FLJ329781 | | WD Repeat-Containing Protein 642 |
Export aliases for WDR64 gene to outside databasesPrevious GC identifers: GC01P238173 GC01P239882 GC01P212273 |
Summaries
for WDR64 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for WDR64 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_167186.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the WDR64 gene promoter:
HTF POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) CUTL1 POU3F2 LCR-F1 GATA-2 C/EBPalpha Ik-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for WDR64
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WDR64 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q43 Ensembl cytogenetic band: 1q43 HGNC cytogenetic band: 1q43WDR64 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P241815: view genomic region
(about GC identifiers)
Start:
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241,815,580 bp from pter |
End:
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241,965,435 bp from pter |
Size:
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149,856 bases |
Orientation:
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plus strand |
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Proteins
for WDR64 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: WDR64_HUMAN, B1ANS9 (See
protein sequence)Recommended Name: WD repeat-containing protein 64 Size: 1081 amino acids; 123631 Da
Sequence caution: Sequence=AAP92796.1; Type=Erroneous initiation; Sequence=BAB71525.1; Type=Erroneous initiation;
Secondary accessions: B1ANT0 Q7Z573 Q96LY9Alternative splicing: 2 isoforms: B1ANS9-1 B1ANS9-2 Explore the universe of human proteins at neXtProt for WDR64: NX_B1ANS9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_B1ANS9
WDR64 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_653226.4
ENSEMBL proteins: ENSP00000425552 ENSP00000406656 ENSP00000431729 ENSP00000406342 ENSP00000355510 ENSP00000402446
Human Recombinant Protein Products:
WDR64 Antibody Products:
Assay Products for WDR64: |
Protein
Domains /
Families
for WDR64 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
WDR64 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry B1ANS9ProtoNet protein and cluster: B1ANS9 UniProtKB/Swiss-Prot: WDR64_HUMAN, B1ANS9Similarity: Contains 12 WD repeats |
Function
for WDR64 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WDR64 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WDR64
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: WDR64 (NM_144625) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for WDR64 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR64 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR64 |
|
Pathways & Interactions
for WDR64 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for WDR64
|
Drugs & Compounds
for WDR64 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for WDR64
Search CenterWatch for drugs/clinical trials and news about WDR64
|
Transcripts
for WDR64 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for WDR64 gene: NM_144625.4 Unigene Cluster for WDR64: WD repeat domain 64 Hs.97527 [show with all ESTs]Unigene Representative Sequence: NM_1446259 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000468967 ENST00000461971 ENST00000496914 ENST00000414635 ENST00000472717
ENST00000425826 ENST00000478331 ENST00000366552(uc001hzg.2) ENST00000437684(uc021plh.1 uc021pli.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WDR64 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WDR64
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: WDR64 (NM_144625) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for WDR64 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR64 |
Additional cDNA sequence: AK057540.1 AK122927.1 AY327404.1 5 DOTS entries: DT.101979133 DT.101979134 DT.40277760 DT.205741 DT.95147648 13 AceView cDNA sequences: BE467936 AK122927 AI001791 AA960789 NM_144625 BG150247 AY327404 BE673668 AI478745 AK057540 AI457225 BE045079 BU198831
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for WDR64 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 |
|---|
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| SP1: | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for WDR64
|
Expression
for WDR64 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| WDR64 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTATGTGTTG
About this image
See WDR64 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for WDR64
SOURCE GeneReport for Unigene cluster: Hs.97527
SABiosciences Custom PCR Arrays for WDR64
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for WDR64
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat WDR64 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDR64 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR64 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR64 |
Orthologs
for WDR64 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for WDR64 gene from 2/12 species (see all 12) About this table
ENSEMBL Gene Tree for WDR64 (if available)
TreeFam Gene Tree for WDR64 (if available) |
Paralogs
for WDR64 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for WDR64 gene
- WDR492
WDR64 for paralogs About GeneDecksing
|
Genomic Variants
for WDR64 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for WDR64 (241815580 - 241965435 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for WDR64
4 CNVs: 84938 84937 97694 74960 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing WDR64 |
|
Disorders
/ Diseases
for WDR64 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
WDR64 for disorders About GeneDecksing
1  disease for WDR64: About MalaCardsmultiple sclerosis
Human Genome Epidemiology (HuGE) Navigator: WDR64 (2 documents)
Export disorders for WDR64 gene to outside databases
|
Publications
for WDR64 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for WDR64 gene integrated from 9 sources:
(articles sorted by number of sources associating them with WDR64) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines. (PubMed id 20923822)1 Niu N....Wang L. (2010)
- Follow-up examination of linkage and association to c hromosome 1q43 in multiple sclerosis. (PubMed id 19626040)1 McCauley J.L....Haines J.L. (2009)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
|
External Searches for WDR64 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing WDR64 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing WDR64 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing WDR64 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for WDR64 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for WDR64 gene:
Search GeneIP for patents involving WDR64
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for WDR64 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for WDR64 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for WDR64 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for WDR64 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for WDR64 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WDR64 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WDR64 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for WDR64 | | OriGene Custom Protein Services for WDR64 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat WDR64 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing WDR64 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WDR64 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat WDR64 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR64 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDR64 |
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 |  |  |  | |
| | | | Search Tocris compounds for WDR64 |
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 | | | WDR64 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR64 |
|  |  |  | | | | Search ThermoFisher Antibodies for WDR64 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR64 |
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