Aliases for WDR60 Gene
External Ids for WDR60 Gene
Previous GeneCards Identifiers for WDR60 Gene
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) and may facilitate the formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein contains four WD repeats and may play a role in the formation of cilia. Mutations in this gene have been associated with short-rib polydactyly and Jeune syndromes. [provided by RefSeq, Mar 2014]
GeneCards Summary for WDR60 Gene
WDR60 (WD Repeat Domain 60) is a Protein Coding gene. Diseases associated with WDR60 include Short-Rib Thoracic Dysplasia 8 With Or Without Polydactyly and Short-Rib Thoracic Dysplasia 3 With Or Without Polydactyly. Among its related pathways are Intraflagellar transport and Organelle biogenesis and maintenance.
UniProtKB/Swiss-Prot for WDR60 Gene
May play a role in ciliogenesis.