WDR60 Gene
protein-coding GIFtS: 41
GCID: GC07P158649
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WD repeat domain 60
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Aliases
for WDR60 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| WD Repeat Domain 601 2 | | FLJ103001 | | WD Repeat-Containing Protein 602 |
Export aliases for WDR60 gene to outside databasesPrevious GC identifers: GC07P158149 GC07P158342 GC07P152387 |
Summaries
for WDR60 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for WDR60 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007741.14 NT_079596.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the WDR60 gene promoter:
ZID Ik-3 Ik-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for WDR60
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WDR60 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q36.3 Ensembl cytogenetic band: 7q36.3 HGNC cytogenetic band: 7q36.3WDR60 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P158649: view genomic region
(about GC identifiers)
Start:
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158,649,269 bp from pter |
End:
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158,749,438 bp from pter |
Size:
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100,170 bases |
Orientation:
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plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 157,852,877-157,941,993 |
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Proteins
for WDR60 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: WDR60_HUMAN, Q8WVS4 (See
protein sequence)Recommended Name: WD repeat-containing protein 60 Size: 1066 amino acids; 122571 Da
Sequence caution: Sequence=BAA91528.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q9NW58Explore the universe of human proteins at neXtProt for WDR60: NX_Q8WVS4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8WVS4
WDR60 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_060521.4
ENSEMBL proteins: ENSP00000384290 ENSP00000380330 ENSP00000392608 ENSP00000399971
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005929 | cilium |
IEA | -- |
WDR60 for ontologies About GeneDecksing
WDR60 Antibody Products:
Assay Products for WDR60: |
Protein
Domains /
Families
for WDR60 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
WDR60 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8WVS4ProtoNet protein and cluster: Q8WVS4 UniProtKB/Swiss-Prot: WDR60_HUMAN, Q8WVS4Similarity: Contains 4 WD repeats |
Function
for WDR60 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WDR60 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WDR60
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: WDR60 (NM_018051) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for WDR60 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR60 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR60 |
|
Pathways & Interactions
for WDR60 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for WDR60
1 Interacting protein for WDR60 (Q8WVS42, 3) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for WDR60 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for WDR60
Search CenterWatch for drugs/clinical trials and news about WDR60
|
Transcripts
for WDR60 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for WDR60 gene: NM_018051.4 Unigene Cluster for WDR60: WD repeat domain 60 Hs.389945 [show with all ESTs]Unigene Representative Sequence: NM_0180515 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000407559(uc003woe.4 uc010lqv.3) ENST00000397143 ENST00000444851
ENST00000467220(uc010lqw.3) ENST00000454771
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WDR60 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WDR60
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: WDR60 (NM_018051) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for WDR60 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR60 |
Additional cDNA sequence: AK001162.1 AK025192.1 AK027228.1 AL137660.1 BC014491.1 12 DOTS entries: DT.209911 DT.121124149 DT.91712285 DT.97812955 DT.86997463 DT.91796216 DT.75100509 DT.86846180 DT.86857822 DT.101965009 DT.121124138 DT.92023399 24/91 AceView cDNA sequences (see all 91): CD721918 CN479201 AL137660 AI745205 AW612747 AL699716 AI816361 BU743018 AI697541 AA436642 AW341045 BM718580 BM836476 NM_018051 BI523955 AF188520 CR627036 AI694886 AI190221 AW070655 BG944610 AA489749 BE467358 BF943234
GeneLoc Exon Structure
|
Expression
for WDR60 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| WDR60 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAAATGTATC
About this image
See WDR60 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for WDR60
SOURCE GeneReport for Unigene cluster: Hs.389945
SABiosciences Custom PCR Arrays for WDR60
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for WDR60
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat WDR60 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDR60 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR60 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR60 |
Orthologs
for WDR60 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for WDR60 gene from 7/20 species (see all 20) About this table
ENSEMBL Gene Tree for WDR60 (if available)
TreeFam Gene Tree for WDR60 (if available) |
Paralogs
for WDR60 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for WDR60 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for WDR60 (158649269 - 158749438 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 42 variations for WDR60
15/30 CNVs (see all 30): 100215 82334 95054 95065 31410 82344 82340 95052 95059 82336 70135 0626 95063 82342 95066
12 Indels: 95062 82345 95061 95049 82339 82335 95064 62759 28582 95057 82341 28579 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing WDR60 |
|
Disorders
/ Diseases
for WDR60 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for WDR60 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for WDR60 gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with WDR60) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
- Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R....Peters J.M. (2010)
- Identification of ten loci associated with height highlights new biological pathways in human growth. (PubMed id 18391950)1 Lettre G....Hirschhorn J.N. (2008)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1 Scherer S.W.... Tsui L.-C. (2003)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)2 Hillier L.W.... Wilson R.K. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for WDR60 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing WDR60 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing WDR60 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing WDR60 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for WDR60 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for WDR60 gene:
Search GeneIP for patents involving WDR60
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for WDR60 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for WDR60 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for WDR60 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for WDR60 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for WDR60 | | OriGene 3'-UTR Clone for WDR60 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WDR60 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WDR60 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for WDR60 | | OriGene Custom Protein Services for WDR60 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat WDR60 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing WDR60 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WDR60 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat WDR60 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR60 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDR60 |
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 |  |  |  | |
| | | | Search Tocris compounds for WDR60 |
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 | | | WDR60 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR60 |
|  |  |  | | | | Search ThermoFisher Antibodies for WDR60 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR60 |
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