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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

WDR5B Gene

protein-coding   GIFtS: 45
GCID: GC03M122081

WD Repeat Domain 5B

  Search for WDR5B
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
WD Repeat Domain 5B1 2
WD Repeat-Containing Protein 5B2

External Ids:    HGNC: 178261   Entrez Gene: 545542   Ensembl: ENSG000001969817   UniProtKB: Q86VZ23   

Export aliases for WDR5B gene to outside databases

Previous GC identifers: GC03M118854 GC03M123412 GC03M123453 GC03M123452 GC03M123613 GC03M119504


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for WDR5B Gene:
This intronless gene encodes a protein containing several WD40 repeats. WD repeats are approximately 30- to
40-amino acid domains containing several conserved residues, including a trp-asp at the C-terminal end. The
encoded protein may mediate protein-protein interactions. (provided by RefSeq, Jul 2008)

GeneCards Summary for WDR5B Gene: 
WDR5B (WD repeat domain 5B) is a protein-coding gene. An important paralog of this gene is WDR83.

UniProtKB/Swiss-Prot: WDR5B_HUMAN, Q86VZ2
Function: May function as a substrate receptor for CUL4-DDB1 ubiquitin E3 ligase complex (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.2  NT_005612.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the WDR5B gene promoter:
         Nkx3-1   Nkx3-1 v4   Nkx3-1 v1   RelA   GATA-1   Nkx3-1 v2   SEF-1 (1)   Nkx3-1 v3   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidWDR5B promoter sequence
   Search SABiosciences Chromatin IP Primers for WDR5B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WDR5B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q21.1   Ensembl cytogenetic band:  3q21.1   HGNC cytogenetic band: 3q21.1

WDR5B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WDR5B gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M122081:  view genomic region     (about GC identifiers)

Start:
122,130,700 bp from pter      End:
122,134,882 bp from pter
Size:
4,183 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: WDR5B_HUMAN, Q86VZ2 (See protein sequence)
Recommended Name: WD repeat-containing protein 5B  
Size: 330 amino acids; 36338 Da
Subunit: Probable part of a cullin-RING E3 protein ligase complex containing CUL4B-DDB1 and a substrate-recruiting
component (DCAF). Interacts with CUL4B and DDB1 (By similarity)
Secondary accessions: B2RCM9 Q9NUL4

Explore the universe of human proteins at neXtProt for WDR5B: NX_Q86VZ2

Explore proteomics data for WDR5B at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q86VZ2

  • WDR5B Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    WDR5B Protein Expression
    REFSEQ proteins: NP_061942.2  
    ENSEMBL proteins: 
     ENSP00000330381  

    Human Recombinant Protein Products for WDR5B: 
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    OriGene Protein Over-expression Lysate for WDR5B
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for WDR5B
    GenScript Custom Purified and Recombinant Proteins Services for WDR5B
    Novus Biologicals WDR5B Protein
    Novus Biologicals WDR5B Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for WDR5B 


    WDR5B Antibody Products: 
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    Cloud-Clone Corp. ELISAs for WDR5B 
    Cloud-Clone Corp. CLIAs for WDR5B


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    WDR: WD repeat domain containing

    5 InterPro protein domains:
     IPR019775 WD40_repeat_CS
     IPR001680 WD40_repeat
     IPR020472 G-protein_beta_WD-40_rep
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q86VZ2

    ProtoNet protein and cluster: Q86VZ2

    1 Blocks protein domain: IPB001632 Beta G-protein (transducin) signature

    UniProtKB/Swiss-Prot: WDR5B_HUMAN, Q86VZ2
    Similarity: Belongs to the WD repeat WDR5/wds family
    Similarity: Contains 7 WD repeats


    WDR5B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: WDR5B_HUMAN, Q86VZ2
    Function: May function as a substrate receptor for CUL4-DDB1 ubiquitin E3 ligase complex (By similarity)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    WDR5B for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for WDR5B:
     Decreased POU5F1-GFP protein e 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for WDR5B 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for WDR5B

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for WDR5B 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for WDR5B 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat WDR5B
    6 QIAGEN miScript miRNA Assays for microRNAs that regulate WDR5B:
    hsa-miR-2114 hsa-miR-595 hsa-miR-96* hsa-miR-3115 hsa-miR-129-5p hsa-miR-150
    SwitchGear 3'UTR luciferase reporter plasmidWDR5B 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for WDR5B
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    Gene Editing
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    Clone
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    OriGene clones in human, mouse for WDR5B (see all 7)
    OriGene ORF clones in mouse, rat for WDR5B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: WDR5B (NM_019069)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for WDR5B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR5B
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                         Customized lentivirus expression plasmids for stable overexpression of WDR5B 

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for WDR5B
    Search LifeMap BioReagents cell lines for WDR5B
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR5B


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for WDR5B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    5/13 Interacting proteins for WDR5B (Q86VZ23 ENSP000003303814) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ASH2LQ9UBL33, ENSP000003408964I2D: score=1 STRING: ENSP00000340896
    GRWD1Q9BQ673, ENSP000002532374I2D: score=1 STRING: ENSP00000253237
    KMT2DO146863, ENSP000003010674I2D: score=1 STRING: ENSP00000301067
    RBBP5Q152913, ENSP000002645154I2D: score=1 STRING: ENSP00000264515
    WDR5P619643, ENSP000003514464I2D: score=1 STRING: ENSP00000351446
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for WDR5B

    Search CenterWatch for drugs/clinical trials and news about WDR5B

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for WDR5B gene: 
    NM_019069.3  

    Unigene Cluster for WDR5B:

    WD repeat domain 5B
    Hs.567513  [show with all ESTs]
    Unigene Representative Sequence: NM_019069
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000330689(uc003efa.1)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat WDR5B
    6 QIAGEN miScript miRNA Assays for microRNAs that regulate WDR5B:
    hsa-miR-2114 hsa-miR-595 hsa-miR-96* hsa-miR-3115 hsa-miR-129-5p hsa-miR-150
    SwitchGear 3'UTR luciferase reporter plasmidWDR5B 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for WDR5B
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat WDR5B
    Clone
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    OriGene clones in human, mouse for WDR5B (see all 7)
    OriGene ORF clones in mouse, rat for WDR5B
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    GenScript: all cDNA clones in your preferred vector: WDR5B (NM_019069)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for WDR5B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR5B
    Sirion Biotech Customized lentivirus for stable overexpression of WDR5B 
                         Customized lentivirus expression plasmids for stable overexpression of WDR5B 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for WDR5B
    OriGene qSTAR qPCR primer pairs in human, mouse for WDR5B
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat WDR5B
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDR5B
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR5B

    Additional mRNA sequence: 

    AK002149.1 AK315186.1 BC025762.1 BC043494.1 CR457279.1 

    4 DOTS entries:

    DT.439023  DT.91669635  DT.100779998  DT.120892719 

    24/80 AceView cDNA sequences (see all 80):

    AA651788 D62687 AA135595 CA432764 CR592490 AA135682 BX097346 CB157726 
    AI091922 BM989318 BC043494 CN478842 AU138933 BQ921194 BC025762 AI092356 
    F11059 BU627497 CA313436 BQ224110 NM_019069 BP351809 BG504014 AL544275 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    WDR5B expression in normal human tissues (normalized intensities)      WDR5B embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGTTGCAAA
    WDR5B Expression
    About this image


    WDR5B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Epithelium (Respiratory System)    fully expand to see all 2 entries
             bronchial epithelial cells   
     
     Adipose (Muscoskeletal System)
             Mesenchymal Stem Cells Subcutaneous White Adipose

    See WDR5B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for WDR5B

    SOURCE GeneReport for Unigene cluster: Hs.567513
        SABiosciences Custom PCR Arrays for WDR5B
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for WDR5B
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR5B
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR5B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for WDR5B gene from 10/21 species (see all 21)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Wdr5b1 , 5 WD repeat domain 5B1, 5 84.81(n)1
    83.79(a)1
      16 (25.43 cM)5
    695441  NM_027113.21  NP_081389.11 
     360411905 
    chicken
    (Gallus gallus)
    Aves WDR56
    WD repeat-containing protein 5
    84(a)
    1 ↔ 1
    17(7198594-7208667)
    lizard
    (Anolis carolinensis)
    Reptilia WDR5B6
    WD repeat domain 5B
    84(a)
    1 ↔ 1
    GL343736.1(5912-21922)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.128202 Xenopus laevis transcribed sequence with strong similarity more 78.4(n)    CB558728.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufk47f042 Danio rerio cDNA clone MGC56591 IMAGE5915175, complete more 76.85(n)    BC052124.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta wds3   -- 84(a)
    (best of 2)
      3A6   --
    worm
    (Caenorhabditis elegans)
    Secernentea C14B1.43 guanine nucleotide binding protein 66(a)
    (best of 3)
      III(3777094-3778384)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PRP46
    Splicing factor, component of the U4/U6-U5 snRNP c...
    18(a)
    1 → many
    XVI(892332-893729)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G027301 transducin/WD40 domain-containing protein 56.91(n)
    59.49(a)
      828189  NM_116507.2  NP_192182.1 
    rice
    (Oryza sativa)
    Liliopsida Os.255322 Oryza sativa (japonica cultivar-group) cDNA clone0 more 70(n)    AK112085.1 


    ENSEMBL Gene Tree for WDR5B (if available)
    TreeFam Gene Tree for WDR5B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for WDR5B gene
    WDR832  POC1B2  WDR52  WDR482  ATG16L12  SNRNP402  PAFAH1B12  SMU12  
    DAW12  PRPF42  WDR382  ATG16L22  POC1A2  
    16 SIMAP similar genes for WDR5B using alignment to 1 protein entry:     WDR5B_HUMAN:
    WDR5    POC1A    DAW1    DKFZp762M0115    POC1B    WDR51B
    FBXW7    WDR57    SNRNP40    WDR83    WDR38    SPAG16
    PAFAH1B1    GNB2L1    PLRG1    SMU1

    WDR5B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/150 SNPs in WDR5B are shown (see all 150)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1922956711,2
    --122130259(+) ACCTAC/TACCAA 1 -- ds50010--------
    rs1123986301,2
    C--122130370(+) TATAAT/-ATGTA 1 -- ds50011Minor allele frequency- -:0.50CSA 2
    rs1814622311,2
    --122130401(+) TTTAAC/TGAAAC 1 -- ds50010--------
    rs58522961,2
    C--122130408(+) AAACCT/-TTTTT 1 -- ds50011Minor allele frequency- -:0.00NA 2
    rs1481307951,2
    --122130520(+) CTCAG-/CCTCCTCA 1 -- ds50010--------
    rs1420379381,2
    --122130536(+) ACTGGC/TATTAT 1 -- ds50010--------
    rs115530851,2
    C,F,H--122130751(+) TGTTAC/TTATGC 1 -- ut3129Minor allele frequency- T:0.49NA NS EA WA CSA 2912
    rs98431651,2
    C,F,H--122131111(+) AGTGGG/CCAGAA 1 -- ut318Minor allele frequency- C:0.24NS EA WA NA 780
    rs1861617071,2
    --122131139(+) ATTTCC/GTGTAA 1 -- ut310--------
    rs1901414131,2
    --122131182(+) GGTTAC/TGGTTA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for WDR5B (122130700 - 122134882 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for WDR5B:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv3973CNV Loss18451855

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing WDR5B
    DNA2.0 Custom Variant and Variant Library Synthesis for WDR5B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for WDR5B gene integrated from 9 sources:
    (articles sorted by number of sources associating them with WDR5B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Extensive gene order differences within regions of conserved synteny between the Fugu and human genomes: implications for chromosomal evolution and the cloning of disease genes. (PubMed id 10369878)1, 3 Gilley J. and Fried M. (1999)
    4. Identification of novel ATP13A2 interactors and their role in a-synuclein misfolding and toxicity. (PubMed id 22645275)1 Usenovic M....Krainc D. (2012)
    5. Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels. (PubMed id 20705733)1 O'Seaghdha C.M....KAPttgen A. (2010)
    6. CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation. (PubMed id 17041588)1 Higa L.A.... Zhang H. (2006)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    8. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
    9. Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. (PubMed id 7566098)1 Adams M.D....White O. (1995)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54554 HGNC: 17826 AceView: WDR5B Ensembl:ENSG00000196981 euGenes: HUgn54554
    ECgene: WDR5B H-InvDB: WDR5B

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for WDR5B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for WDR5B gene:
    Search GeneIP for patents involving WDR5B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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