Free for academic non-profit institutions. Other users need a Commercial license

Aliases for WDR55 Gene

Aliases for WDR55 Gene

  • WD Repeat Domain 55 2 3

External Ids for WDR55 Gene

Previous GeneCards Identifiers for WDR55 Gene

  • GC05P140026
  • GC05P140044
  • GC05P135189

Summaries for WDR55 Gene

GeneCards Summary for WDR55 Gene

WDR55 (WD Repeat Domain 55) is a Protein Coding gene.

UniProtKB/Swiss-Prot for WDR55 Gene

  • Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis (By similarity).

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR55 Gene

Genomics for WDR55 Gene

Regulatory Elements for WDR55 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for WDR55 Gene

140,664,676 bp from pter
140,674,124 bp from pter
9,449 bases
Plus strand

Genomic View for WDR55 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for WDR55 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WDR55 Gene

Proteins for WDR55 Gene

  • Protein details for WDR55 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    WD repeat-containing protein 55
    Protein Accession:
    Secondary Accessions:
    • Q9NXK4

    Protein attributes for WDR55 Gene

    383 amino acids
    Molecular mass:
    42070 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for WDR55 Gene


neXtProt entry for WDR55 Gene

Proteomics data for WDR55 Gene at MOPED

Post-translational modifications for WDR55 Gene

  • Ubiquitination at Lys320
  • Modification sites at PhosphoSitePlus

Other Protein References for WDR55 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for WDR55 Gene

Domains for WDR55 Gene

Gene Families for WDR55 Gene

  • WDR :WD repeat domain containing

Protein Domains for WDR55 Gene

Suggested Antigen Peptide Sequences for WDR55 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q9H6Y2
  • Belongs to the WD repeat WDR55 family.
  • Contains 7 WD repeats.
genes like me logo Genes that share domains with WDR55: view

Function for WDR55 Gene

Molecular function for WDR55 Gene

UniProtKB/Swiss-Prot Function: Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis (By similarity).

Gene Ontology (GO) - Molecular Function for WDR55 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with WDR55: view

Phenotypes for WDR55 Gene

MGI mutant phenotypes for WDR55:
inferred from 1 alleles
genes like me logo Genes that share phenotypes with WDR55: view

Animal Models for WDR55 Gene

MGI Knock Outs for WDR55:

Animal Model Products

CRISPR Products

miRNA for WDR55 Gene

miRTarBase miRNAs that target WDR55

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targeting and HOMER Transcription for WDR55 Gene

Localization for WDR55 Gene

Subcellular locations from UniProtKB/Swiss-Prot for WDR55 Gene

Nucleus, nucleolus. Cytoplasm.

Subcellular locations from

Jensen Localization Image for WDR55 Gene COMPARTMENTS Subcellular localization image for WDR55 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for WDR55 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0005634 nucleus IBA --
GO:0005730 nucleolus ISS --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with WDR55: view

Pathways for WDR55 Gene

SuperPathways for WDR55 Gene

No Data Available

Interacting Proteins for WDR55 Gene

Gene Ontology (GO) - Biological Process for WDR55 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006364 rRNA processing ISS --
GO:0008150 biological_process ND --
GO:0016070 RNA metabolic process IBA --
GO:0042273 ribosomal large subunit biogenesis IBA --
genes like me logo Genes that share ontologies with WDR55: view

No data available for Pathways by source for WDR55 Gene

Transcripts for WDR55 Gene

Unigene Clusters for WDR55 Gene

WD repeat domain 55:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for WDR55

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for WDR55

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for WDR55 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7

Relevant External Links for WDR55 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for WDR55 Gene

mRNA expression in normal human tissues for WDR55 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for WDR55 Gene

SOURCE GeneReport for Unigene cluster for WDR55 Gene Hs.286261

genes like me logo Genes that share expressions with WDR55: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for WDR55 Gene

Orthologs for WDR55 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for WDR55 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia WDR55 35
  • 99.22 (n)
  • 99.48 (a)
WDR55 36
  • 99 (a)
(Bos Taurus)
Mammalia WDR55 35
  • 89.61 (n)
  • 93.22 (a)
WDR55 36
  • 92 (a)
(Canis familiaris)
Mammalia WDR55 35
  • 89.49 (n)
  • 92.72 (a)
WDR55 36
  • 41 (a)
(Mus musculus)
Mammalia Wdr55 35
  • 83.12 (n)
  • 88.25 (a)
Wdr55 16
Wdr55 36
  • 87 (a)
(Monodelphis domestica)
Mammalia WDR55 36
  • 34 (a)
(Ornithorhynchus anatinus)
Mammalia WDR55 36
  • 78 (a)
(Rattus norvegicus)
Mammalia Wdr55 35
  • 84.51 (n)
  • 89.56 (a)
(Gallus gallus)
Aves WDR55 35
  • 69.8 (n)
  • 68.24 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.15646 35
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100490380 35
  • 64.52 (n)
  • 65.05 (a)
Str.15755 35
(Danio rerio)
Actinopterygii wdr55 35
  • 62.17 (n)
  • 63.07 (a)
wdr55 36
  • 60 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP008286 35
  • 47.89 (n)
  • 37.07 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG14722 35
  • 46.76 (n)
  • 34.93 (a)
CG14722 36
  • 24 (a)
(Caenorhabditis elegans)
Secernentea Y44F5A.1 36
  • 23 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G34260 35
  • 47.95 (n)
  • 38.36 (a)
(Oryza sativa)
Liliopsida Os07g0660700 35
  • 46.78 (n)
  • 39.66 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 34 (a)
Species with no ortholog for WDR55:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for WDR55 Gene

Gene Tree for WDR55 (if available)
Gene Tree for WDR55 (if available)

Paralogs for WDR55 Gene Pseudogenes for WDR55 Gene

genes like me logo Genes that share paralogs with WDR55: view

No data available for Paralogs for WDR55 Gene

Variants for WDR55 Gene

Sequence variations from dbSNP and Humsavar for WDR55 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs2251860 -- 140,668,624(-) AGACT(A/G)TTGAT synonymous-codon, reference, utr-variant-5-prime
rs2286394 - 140,668,959(-) CCCCA(A/G)ACTGA reference, missense
rs2302104 -- 140,668,015(-) TTTGC(A/G)CAAGA intron-variant
rs2530245 - 140,668,682(-) GAGAC(A/G)GATAC missense, reference, utr-variant-5-prime
rs2530246 -- 140,667,426(-) GGAGG(C/G)AGCAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for WDR55 Gene

Variant ID Type Subtype PubMed ID
nsv471435 CNV Duplication 19718026

Relevant External Links for WDR55 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WDR55 Gene

Disorders for WDR55 Gene

Relevant External Links for WDR55

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with WDR55: view

No data available for UniProtKB/Swiss-Prot for WDR55 Gene

Publications for WDR55 Gene

  1. Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study. (PMID: 17975119) Shiffman D. … Psaty B.M. (Arterioscler. Thromb. Vasc. Biol. 2008) 3 48
  2. Gene variants associated with ischemic stroke: the cardiovascular health study. (PMID: 19023099) Luke M.M. … Psaty B.M. (Stroke 2009) 3 48
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4

Products for WDR55 Gene

Sources for WDR55 Gene

Back to Top