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WDR43 Gene

protein-coding   GIFtS: 49
GCID: GC02P029117

WD Repeat Domain 43

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
WD Repeat Domain 431 2     NET122
UTP51 2 3     UTP5, Small Subunit (SSU) Processome Component, Homolog2
Homolog (Yeast)1     WD Repeat-Containing Protein 432
Small Subunit (SSU) Processome Component1     KIAA00073

External Ids:    HGNC: 289451   Entrez Gene: 231602   Ensembl: ENSG000001638117   UniProtKB: Q150613   

Export aliases for WDR43 gene to outside databases

Previous GC identifers: GC02P029004 GC02P028946 GC02P028859


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for WDR43 Gene:
WDR43 (WD repeat domain 43) is a protein-coding gene. Diseases associated with WDR43 include malaria.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the WDR43 gene promoter:
         NF-1   NF-1/L   Lmo2   LCR-F1   AP-2gamma   c-Myb   AP-2beta   Pax-4a   AP-2alpha   AP-2alphaA   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for WDR43

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat WDR43


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p23.2   Ensembl cytogenetic band:  2p23.2   HGNC cytogenetic band: 2p23.3

WDR43 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WDR43 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P029117:  view genomic region     (about GC identifiers)

Start:
29,117,509 bp from pter      End:
29,171,088 bp from pter
Size:
53,580 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: WDR43_HUMAN, Q15061 (See protein sequence)
Recommended Name: WD repeat-containing protein 43  
Size: 677 amino acids; 74891 Da
Subunit: Forms a complex with CIRH1A, NOL11, UTP15 and WDR75
Sequence caution: Sequence=BAA05499.1; Type=Erroneous initiation; Sequence=BAA05499.1; Type=Frameshift;
Positions=614, 617;
Secondary accessions: Q15395 Q92577

Explore the universe of human proteins at neXtProt for WDR43: NX_Q15061

Explore proteomics data for WDR43 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys181, Lys191
  • Modification sites at PhosphoSitePlus

  • See WDR43 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055946.1  
    ENSEMBL proteins: 
     ENSP00000384302   ENSP00000390363   ENSP00000415355   ENSP00000296126   ENSP00000406083  

    WDR43 Human Recombinant Protein Products:

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    OriGene Purified Protein for WDR43
    OriGene Protein Over-expression Lysate for WDR43
    OriGene Custom MassSpec
    OriGene Custom Protein Services for WDR43
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    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for WDR43

    WDR43 Antibody Products:

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    Abcam antibodies for WDR43
    Cloud-Clone Corp. Antibodies for WDR43
    ThermoFisher Antibody for WDR43
    LSBio Antibodies in human, mouse, rat for WDR43

    WDR43 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for WDR43
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for WDR43
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for WDR43
    Cloud-Clone Corp. CLIAs for WDR43


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    WDR: WD repeat domain containing

    4 InterPro protein domains:
     IPR001680 WD40_repeat
     IPR007148 SSU_processome_Utp12
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q15061

    ProtoNet protein and cluster: Q15061

    1 Blocks protein domain: IPB012979 Protein of unknown function NUC189

    UniProtKB/Swiss-Prot: WDR43_HUMAN, Q15061
    Similarity: Belongs to the UTP5 family
    Similarity: Contains 6 WD repeats


    WDR43 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
    GO:0005515protein binding ----
    GO:0044822poly(A) RNA binding IDA--
         
    WDR43 for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for WDR43:
     Decreased TP53 protein express  Decreased viability of wild-ty  Increased S DNA content, incre  Nuclear 60S biogenesis defects 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for WDR43
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for WDR43

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for WDR43
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for WDR43

    miRNA
    Products:
        
    miRTarBase miRNAs that target WDR43:
    hsa-mir-16-5p (MIRT031487), hsa-mir-877-3p (MIRT037019), hsa-mir-30b-5p (MIRT046118)

    Block miRNA regulation of human, mouse, rat WDR43 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate WDR43 (see all 23):
    hsa-miR-4311 hsa-miR-136 hsa-miR-640 hsa-miR-520d-5p hsa-miR-513a-5p hsa-miR-200a hsa-miR-340 hsa-miR-141
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for WDR43
    Predesigned siRNA for gene silencing in human, mouse, rat WDR43

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for WDR43

    Clone
    Products:
         
    OriGene clones in human, mouse for WDR43 (see all 6)
    OriGene ORF clones in mouse, rat for WDR43
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: WDR43 (NM_015131)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for WDR43
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR43

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for WDR43 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR43


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    WDR43_HUMAN, Q15061: Nucleus, nucleolus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IEA--

    WDR43 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for WDR43 About    
    See pathways by source

    SuperPathContained pathways About
    1Ribosome biogenesis in eukaryotes
    Ribosome biogenesis in eukaryotes

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for WDR43):
        Ribosome biogenesis in eukaryotes


    WDR43 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for WDR43
    Interactions:

        Search GeneGlobe Interaction Network for WDR43

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for WDR43 (Q150613 ENSP000003843024) via UniProtKB, MINT, STRING, and/or I2D (see all 98)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CSO753903I2D: score=2 
    VAMP2P630273I2D: score=2 
    HEATR1ENSP000003555414STRING: ENSP00000355541
    CIRH1AENSP000003271794STRING: ENSP00000327179
    UTP15ENSP000002967924STRING: ENSP00000296792
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for WDR43



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for WDR43 gene: 
    NM_015131.1  

    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000407426(uc002rmo.2) ENST00000434238 ENST00000440983 ENST00000296126
    ENST00000466067 ENST00000446643
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat WDR43 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate WDR43 (see all 23):
    hsa-miR-4311 hsa-miR-136 hsa-miR-640 hsa-miR-520d-5p hsa-miR-513a-5p hsa-miR-200a hsa-miR-340 hsa-miR-141
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for WDR43
    Predesigned siRNA for gene silencing in human, mouse, rat WDR43
    Clone
    Products:
         
    OriGene clones in human, mouse for WDR43 (see all 6)
    OriGene ORF clones in mouse, rat for WDR43
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: WDR43 (NM_015131)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for WDR43
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR43
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for WDR43
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat WDR43
      QuantiTect SYBR Green Assays in human, mouse, rat WDR43
      QuantiFast Probe-based Assays in human, mouse, rat WDR43

    Selected AceView cDNA sequences (see all 142):

    AW593733 BE408569 AL532397 BG036013 BQ053985 T29045 AW009935 BX475682 
    CR612320 AA315159 CR618449 BM473523 BG760680 AW999532 BU188794 AA865370 
    BI061925 CB133931 CB126579 AI669485 BG825535 BX954765 BM754426 BM825148 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    WDR43 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAAGCTCACC
    WDR43 Expression
    About this image

    WDR43 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    WDR43 Protein Expression
        Custom PCR Arrays for WDR43
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for WDR43
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat WDR43
    QuantiTect SYBR Green Assays in human, mouse, rat WDR43
    QuantiFast Probe-based Assays in human, mouse, rat WDR43
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR43

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for WDR43 gene from Selected species (see all 23)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Wdr431 , 5 WD repeat domain 431, 5 84.44(n)1
    85.33(a)1
      17 (41.87 cM)5
    725151  NM_175639.11  NP_783570.11 
     716162155 
    chicken
    (Gallus gallus)
    Aves WDR431 WD repeat domain 43 71.87(n)
    70.64(a)
      421295  NM_001006396.1  NP_001006396.1 
    lizard
    (Anolis carolinensis)
    Reptilia WDR436
    WD repeat domain 43
    66(a)
    1 ↔ 1
    1(248317000-248354687)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC043856.12   -- 75.57(n)    BC043856.1 
    zebrafish
    (Danio rerio)
    Actinopterygii AF506230.12   -- 72.77(n)   317637  AF506230.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG303491 CG30349 40.33(n)
    28.82(a)
      35885  NM_136577.1  NP_610421.1 
    worm
    (Caenorhabditis elegans)
    Secernentea T10B5.36
    Protein T10B5.3 (T10B5.3) mRNA, complete cds
    25(a)
    1 ↔ 1
    V(1864191-1868567) WBGene00020389
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes UTP5(YDR398W)4
    UTP51
    Subunit of U3-containing Small Subunit (SSU) processome more4
    UTP51
    43.3(n)1
    31.07(a)1
      4(1267471-1269402)4
    8520071, 4  NP_010686.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G112401 AT5G11240 41.54(n)
    27.15(a)
      830994  NM_121162.4  NP_196685.2 
    rice
    (Oryza sativa)
    Liliopsida Os03g03003001 Os03g0300300 41.7(n)
    27.61(a)
      4332567  NM_001056391.1  NP_001049856.1 


    ENSEMBL Gene Tree for WDR43 (if available)
    TreeFam Gene Tree for WDR43 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for WDR43 (see all 1161)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1915729301,2
    --29115691(+) GAACCA/GGAAGG 1 -- us2k10--------
    rs1827998991,2
    --29115703(+) GGAGGC/TTGCAG 1 -- us2k10--------
    rs1478038211,2
    C--29115712(+) AGTGAA/GCTGAG 1 -- us2k10--------
    rs1867997671,2
    --29115818(+) GCTCCA/GTAGCT 1 -- us2k10--------
    rs1897198481,2
    --29115832(+) AAAGCA/TTGAGC 1 -- us2k10--------
    rs1142381321,2
    C,F--29115845(+) TCCCAT/CGGCCA 1 -- us2k11Minor allele frequency- C:0.02NA 120
    rs1416637041,2
    --29115867(+) TTTATC/TTTTCC 1 -- us2k10--------
    rs1461997111,2
    --29116169(+) AATAGC/TTGTTC 1 -- us2k10--------
    rs1391051521,2
    C--29116175(+) TGTTCC/TGATCA 1 -- us2k10--------
    rs1822473331,2
    --29116188(+) ACTTTC/TACATT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for WDR43 (29117509 - 29171088 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for WDR43:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1693261CNV Deletion17803354
    esv2719844CNV Deletion23290073
    nsv817695CNV Gain17921354

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing WDR43
    DNA2.0 Custom Variant and Variant Library Synthesis for WDR43

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for WDR43:    
    About MalaCards
    malaria


    WDR43 for disorders           About GeneDecksing


    Export disorders for WDR43 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for WDR43 gene, integrated from 10 sources (see all 28):
    (articles sorted by number of sources associating them with WDR43)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. (PubMed id 7584026)1, 2, 3 Nomura N.... Tabata S. (DNA Res. 1994)
    2. Recruitment of factors linking transcription and processing of pre-rRNA to NOR chromatin is UBF-dependent and occurs independent of transcription in human cells. (PubMed id 17699751)1, 3 Prieto J.L. and McStay B. (amp 2007)
    3. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (Nat. Biotechnol. 2006)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    5. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (Mol. Biol. Cell 2002)
    6. Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement). (PubMed id 7584028)1, 3 Nomura N....Tabata S. (DNA Res. 1994)
    7. VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (PLoS ONE 2013)
    8. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23160 HGNC: 28945 AceView: WDR43 Ensembl:ENSG00000163811 euGenes: HUgn23160
    ECgene: WDR43 Kegg: 23160 H-InvDB: WDR43

    (According to HUGE)
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    HUGE: KIAA0007

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for WDR43 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for WDR43 gene:
    Search GeneIP for patents involving WDR43

    GeneCards and IP:
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