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Aliases for WDR43 Gene

Aliases for WDR43 Gene

  • WD Repeat Domain 43 2 3
  • UTP5 2 3 4
  • UTP5, Small Subunit (SSU) Processome Component, Homolog 3
  • Small Subunit (SSU) Processome Component 2
  • WD Repeat-Containing Protein 43 3
  • Homolog (Yeast) 2
  • KIAA0007 4
  • NET12 3

External Ids for WDR43 Gene

Previous GeneCards Identifiers for WDR43 Gene

  • GC02P029004
  • GC02P028946
  • GC02P029117

Summaries for WDR43 Gene

GeneCards Summary for WDR43 Gene

WDR43 (WD Repeat Domain 43) is a Protein Coding gene. Among its related pathways are Ribosome biogenesis in eukaryotes.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR43 Gene

Genomics for WDR43 Gene

Regulatory Elements for WDR43 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for WDR43 Gene

28,894,643 bp from pter
28,948,222 bp from pter
53,580 bases
Plus strand

Genomic View for WDR43 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for WDR43 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WDR43 Gene

Proteins for WDR43 Gene

  • Protein details for WDR43 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    WD repeat-containing protein 43
    Protein Accession:
    Secondary Accessions:
    • Q15395
    • Q92577

    Protein attributes for WDR43 Gene

    677 amino acids
    Molecular mass:
    74891 Da
    Quaternary structure:
    • Forms a complex with CIRH1A, NOL11, UTP15 and WDR75.
    • Sequence=BAA05499.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAA05499.1; Type=Frameshift; Positions=614, 617; Evidence={ECO:0000305};

neXtProt entry for WDR43 Gene

Proteomics data for WDR43 Gene at MOPED

Post-translational modifications for WDR43 Gene

  • Ubiquitination at Lys181 and Lys191
  • Modification sites at PhosphoSitePlus

Other Protein References for WDR43 Gene

No data available for DME Specific Peptides for WDR43 Gene

Domains for WDR43 Gene

Gene Families for WDR43 Gene

  • WDR :WD repeat domain containing

Suggested Antigen Peptide Sequences for WDR43 Gene

Graphical View of Domain Structure for InterPro Entry



  • Q15061
  • Belongs to the UTP5 family.
  • Contains 6 WD repeats.
genes like me logo Genes that share domains with WDR43: view

Function for WDR43 Gene

Gene Ontology (GO) - Molecular Function for WDR43 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005488 binding --
GO:0005515 protein binding --
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with WDR43: view
genes like me logo Genes that share phenotypes with WDR43: view

Animal Model Products

CRISPR Products

miRNA for WDR43 Gene

miRTarBase miRNAs that target WDR43

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for WDR43 Gene

Localization for WDR43 Gene

Subcellular locations from UniProtKB/Swiss-Prot for WDR43 Gene

Nucleus, nucleolus.

Subcellular locations from

Jensen Localization Image for WDR43 Gene COMPARTMENTS Subcellular localization image for WDR43 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for WDR43 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
GO:0005730 nucleolus IEA --
genes like me logo Genes that share ontologies with WDR43: view

Pathways for WDR43 Gene

genes like me logo Genes that share pathways with WDR43: view

Pathways by source for WDR43 Gene

1 KEGG pathway for WDR43 Gene

Interacting Proteins for WDR43 Gene

Gene Ontology (GO) - Biological Process for WDR43 Gene


Transcripts for WDR43 Gene

Unigene Clusters for WDR43 Gene

WD repeat domain 43:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for WDR43

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for WDR43

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for WDR43 Gene

No ASD Table

Relevant External Links for WDR43 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for WDR43 Gene

mRNA expression in normal human tissues for WDR43 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for WDR43 Gene

SOURCE GeneReport for Unigene cluster for WDR43 Gene Hs.709228

genes like me logo Genes that share expressions with WDR43: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for WDR43 Gene

Orthologs for WDR43 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for WDR43 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia WDR43 35
  • 99.56 (n)
  • 99.7 (a)
WDR43 36
  • 100 (a)
(Bos Taurus)
Mammalia WDR43 35
  • 90.98 (n)
  • 91.72 (a)
WDR43 36
  • 92 (a)
(Canis familiaris)
Mammalia WDR43 35
  • 89.35 (n)
  • 91.12 (a)
WDR43 36
  • 93 (a)
(Mus musculus)
Mammalia Wdr43 35
  • 84.44 (n)
  • 85.33 (a)
Wdr43 16
Wdr43 36
  • 86 (a)
(Monodelphis domestica)
Mammalia WDR43 36
  • 80 (a)
(Ornithorhynchus anatinus)
Mammalia WDR43 36
  • 75 (a)
(Rattus norvegicus)
Mammalia Wdr43 35
  • 83.68 (n)
  • 85.76 (a)
(Gallus gallus)
Aves WDR43 35
  • 71.87 (n)
  • 70.64 (a)
WDR43 36
  • 72 (a)
(Anolis carolinensis)
Reptilia WDR43 36
  • 66 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia wdr43 35
  • 63.95 (n)
  • 63.05 (a)
(Danio rerio)
Actinopterygii -- 35
wdr43 35
  • 59.94 (n)
  • 55.9 (a)
wdr43 36
  • 56 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP010698 35
  • 38.78 (n)
  • 27.09 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG30349 35
  • 40.33 (n)
  • 28.82 (a)
CG30349 36
  • 27 (a)
(Caenorhabditis elegans)
Secernentea T10B5.3 36
  • 25 (a)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AFR398W 35
  • 39.29 (n)
  • 28.24 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes UTP5 35
  • 43.3 (n)
  • 31.07 (a)
UTP5 36
  • 22 (a)
UTP5 38
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0C06633g 35
  • 41.46 (n)
  • 28.6 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G11240 35
  • 41.54 (n)
  • 27.15 (a)
(Oryza sativa)
Liliopsida Os03g0300300 35
  • 41.7 (n)
  • 27.61 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes utp5 35
  • 39.75 (n)
  • 27.18 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.5747 36
  • 29 (a)
Species with no ortholog for WDR43:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for WDR43 Gene

Gene Tree for WDR43 (if available)
Gene Tree for WDR43 (if available)

Paralogs for WDR43 Gene

No data available for Paralogs for WDR43 Gene

Variants for WDR43 Gene

Sequence variations from dbSNP and Humsavar for WDR43 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs1131880 -- 28,947,810(+) TTTAT(C/G)TATGT utr-variant-3-prime
rs1131881 -- 28,947,847(+) CCTTT(A/G)CAAAT utr-variant-3-prime
rs1137797 -- 28,935,378(+) CAACC(C/T)TTATT intron-variant
rs1140697 -- 28,929,590(+) ATTGA(A/G)GAACG reference, synonymous-codon
rs3087649 -- 28,946,746(-) TCTAA(A/G)TCAGA synonymous-codon, reference

Structural Variations from Database of Genomic Variants (DGV) for WDR43 Gene

Variant ID Type Subtype PubMed ID
nsv817695 CNV Gain 17921354
esv2719844 CNV Deletion 23290073
esv1693261 CNV Deletion 17803354

Relevant External Links for WDR43 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WDR43 Gene

Disorders for WDR43 Gene

No disorders were found for WDR43 Gene.

No data available for UniProtKB/Swiss-Prot for WDR43 Gene

Publications for WDR43 Gene

  1. Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. (PMID: 7584026) Nomura N. … Tabata S. (DNA Res. 1994) 2 3 4
  2. Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement). (PMID: 7584028) Nomura N. … Tabata S. (DNA Res. 1994) 2 3
  3. Functional proteomic analysis of human nucleolus. (PMID: 12429849) Scherl A. … Diaz J.-J. (Mol. Biol. Cell 2002) 3 4
  4. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PMID: 16964243) Beausoleil S.A. … Gygi S.P. (Nat. Biotechnol. 2006) 3 4
  5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4

Products for WDR43 Gene

Sources for WDR43 Gene

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