WDR41 Gene
protein-coding GIFtS: 41
GCID: GC05M076721
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WD repeat domain 41
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Aliases
for WDR41 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| WD Repeat Domain 411 2 | | FLJ109041 | | WD Repeat-Containing Protein 412 |
Export aliases for WDR41 gene to outside databasesPrevious GC identifers: GC05M076813 GC05M076763 GC05M071934 |
Summaries
for WDR41 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for WDR41 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_006713.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the WDR41 gene promoter:
NF-AT Arnt AREB6 NF-AT4 IRF-2 NF-AT2 FOXO1a NF-AT3 FOXO1 NF-AT1
Other transcription factors
Search SABiosciences Chromatin IP Primers for WDR41
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WDR41 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q13.3 Ensembl cytogenetic band: 5q14.1 HGNC cytogenetic band: 5q14WDR41 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05M076721: view genomic region
(about GC identifiers)
Start:
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76,721,795 bp from pter |
End:
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76,916,436 bp from pter |
Size:
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194,642 bases |
Orientation:
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minus strand |
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Proteins
for WDR41 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: WDR41_HUMAN, Q9HAD4 (See
protein sequence)Recommended Name: WD repeat-containing protein 41 Size: 459 amino acids; 51728 Da
Sequence caution: Sequence=AAO06948.1; Type=Frameshift; Positions=188;
Secondary accessions: Q7Z792 Q8IWG3 Q8IXA9 Q8NDA7 Q9NV62Explore the universe of human proteins at neXtProt for WDR41: NX_Q9HAD4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9HAD4
WDR41 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_060738.2
ENSEMBL proteins: ENSP00000296679 ENSP00000426499 ENSP00000424287 ENSP00000425563 ENSP00000427291 ENSP00000427652 ENSP00000423540 ENSP00000425249 ENSP00000424327 ENSP00000427219 ENSP00000423462 ENSP00000426937 ENSP00000421166 ENSP00000422510 ENSP00000426141 ENSP00000422922 ENSP00000425813 ENSP00000392931
Human Recombinant Protein Products:
WDR41 Antibody Products:
Assay Products for WDR41: |
Protein
Domains /
Families
for WDR41 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
WDR41 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9HAD4ProtoNet protein and cluster: Q9HAD4 UniProtKB/Swiss-Prot: WDR41_HUMAN, Q9HAD4Similarity: Contains 6 WD repeats |
Function
for WDR41 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WDR41 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WDR41 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: WDR41 (NM_018268) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for WDR41 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR41 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR41 |
|
Pathways & Interactions
for WDR41 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for WDR41
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for WDR41 (Q9HAD43 ENSP000002966794) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for WDR41 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for WDR41
Search CenterWatch for drugs/clinical trials and news about WDR41
|
Transcripts
for WDR41 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for WDR41 gene: NM_018268.2 Unigene Cluster for WDR41: WD repeat domain 41 Hs.482573 [show with all ESTs]Unigene Representative Sequence: AL83413818/29 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 29): ENST00000514878 ENST00000512033 ENST00000508154 ENST00000296679(uc003kff.1 uc011csy.1 uc011csz.1 uc011cta.1 uc011ctb.1)
ENST00000502528 ENST00000515253 ENST00000507029 ENST00000511630 ENST00000507654
ENST00000509701 ENST00000511791 ENST00000505129 ENST00000506307 ENST00000507452
ENST00000509892 ENST00000515321 ENST00000513417 ENST00000514559
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WDR41 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WDR41 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: WDR41 (NM_018268) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for WDR41 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR41 |
Additional cDNA sequence: AF115511.1 AK001766.1 AK021855.1 AK023977.1 AK293316.1 AK295249.1 AK296423.1 AK300058.1 AK304329.1 AL834138.1 BC001807.1 BC040241.1 13 DOTS entries: DT.317436 DT.99928286 DT.454882 DT.92434568 DT.120884503 DT.120884517 DT.120884549 DT.92396000 DT.92434560 DT.95174198 DT.95174199 DT.120884594 DT.99967074 24/308 AceView cDNA sequences (see all 308): T87894 AI087179 AW151776 AA902245 BM975454 BM802697 AI917015 AA825403 CR625903 N33742 BU627096 BQ000743 BM974328 CR616409 CA429646 BP357514 BU182042 BM754574 AI474186 AA190883 AA278159 AA453973 AL599014 AW274855
GeneLoc Exon Structure
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Expression
for WDR41 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| WDR41 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TACGCCAAGG
About this image
See WDR41 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for WDR41
SOURCE GeneReport for Unigene cluster: Hs.482573
SABiosciences Custom PCR Arrays for WDR41
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for WDR41
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat WDR41 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDR41 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR41 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR41 |
Orthologs
for WDR41 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for WDR41 gene from 5/13 species (see all 13) About this table
ENSEMBL Gene Tree for WDR41 (if available)
TreeFam Gene Tree for WDR41 (if available) |
Paralogs
for WDR41 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for WDR41 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for WDR41 (76721795 - 76916436 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for WDR41
1 Indel: 59273 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing WDR41 |
|
Disorders
/ Diseases
for WDR41 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 WDR41 for disorders About MalaCards
WDR41 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: WDR41 (4 documents)
Export disorders for WDR41 gene to outside databases
|
Publications
for WDR41 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for WDR41 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with WDR41) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Discovery and replication of dopamine-related gene ef fects on caudate volume in young and elderly populations (N=1198) using genome- wide search. (PubMed id 21502949)1 Stein J.L....Thompson P.M. (2011)
- Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
- Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
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External Searches for WDR41 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing WDR41 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing WDR41 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing WDR41 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for WDR41 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for WDR41 gene:
Search GeneIP for patents involving WDR41
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for WDR41 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for WDR41 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for WDR41 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for WDR41 | | | OriGene Protein Over-expression Lysate for WDR41 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for WDR41 | | OriGene 3'-UTR Clone for WDR41 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WDR41 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WDR41 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for WDR41 | | OriGene Custom Protein Services for WDR41 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat WDR41 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing WDR41 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WDR41 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat WDR41 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR41 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDR41 |
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| | | | Search Tocris compounds for WDR41 |
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 | | | WDR41 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR41 |
|  |  |  | | | | ThermoFisher Antibodies for WDR41 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR41 |
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