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Aliases for WDR41 Gene

Aliases for WDR41 Gene

  • WD Repeat Domain 41 2 3
  • WD Repeat-Containing Protein 41 3
  • MSTP048 3

External Ids for WDR41 Gene

Summaries for WDR41 Gene

GeneCards Summary for WDR41 Gene

WDR41 (WD Repeat Domain 41) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR41 Gene

Genomics for WDR41 Gene

Genomic Location for WDR41 Gene

Start:
77,425,970 bp from pter
End:
77,620,611 bp from pter
Size:
194,642 bases
Orientation:
Minus strand

Genomic View for WDR41 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for WDR41 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WDR41 Gene

Regulatory Elements for WDR41 Gene

Proteins for WDR41 Gene

  • Protein details for WDR41 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9HAD4-WDR41_HUMAN
    Recommended name:
    WD repeat-containing protein 41
    Protein Accession:
    Q9HAD4
    Secondary Accessions:
    • B4DT55
    • Q7Z792
    • Q8IWG3
    • Q8IXA9
    • Q8NDA7
    • Q9NV62

    Protein attributes for WDR41 Gene

    Size:
    459 amino acids
    Molecular mass:
    51728 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAO06948.1; Type=Frameshift; Positions=188; Evidence={ECO:0000305};

    Alternative splice isoforms for WDR41 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for WDR41 Gene

Proteomics data for WDR41 Gene at MOPED

Post-translational modifications for WDR41 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys276, Lys319, and Lys354

No data available for DME Specific Peptides for WDR41 Gene

Domains for WDR41 Gene

Gene Families for WDR41 Gene

HGNC:
  • WDR :WD repeat domain containing

UniProtKB/Swiss-Prot:

WDR41_HUMAN
Similarity:
  • Contains 6 WD repeats.:
    • Q9HAD4
genes like me logo Genes that share domains with WDR41: view

Function for WDR41 Gene

Gene Ontology (GO) - Molecular Function for WDR41 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with WDR41: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for WDR41 Gene

Localization for WDR41 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for WDR41 Gene COMPARTMENTS Subcellular localization image for WDR41 gene
Compartment Confidence
cytosol 2
mitochondrion 2
endoplasmic reticulum 1
golgi apparatus 1
nucleus 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for WDR41 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005765 lysosomal membrane IDA 17897319
genes like me logo Genes that share ontologies with WDR41: view

Pathways for WDR41 Gene

SuperPathways for WDR41 Gene

No Data Available

Interacting Proteins for WDR41 Gene

Gene Ontology (GO) - Biological Process for WDR41 Gene

None

No data available for Pathways by source for WDR41 Gene

Transcripts for WDR41 Gene

Unigene Clusters for WDR41 Gene

WD repeat domain 41:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for WDR41 Gene

No ASD Table

Relevant External Links for WDR41 Gene

GeneLoc Exon Structure for
WDR41
ECgene alternative splicing isoforms for
WDR41

Expression for WDR41 Gene

mRNA expression in normal human tissues for WDR41 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for WDR41 Gene

SOURCE GeneReport for Unigene cluster for WDR41 Gene Hs.482573

genes like me logo Genes that share expressions with WDR41: view

Orthologs for WDR41 Gene

This gene was present in the common ancestor of chordates.

Orthologs for WDR41 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia WDR41 36
  • 99.64 (n)
  • 99.35 (a)
WDR41 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia WDR41 36
  • 91.21 (n)
  • 89.98 (a)
WDR41 37
  • 90 (a)
OneToOne
dog
(Canis familiaris)
Mammalia WDR41 36
  • 93.03 (n)
  • 92.36 (a)
WDR41 37
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Wdr41 36
  • 83.26 (n)
  • 85.53 (a)
Wdr41 16
Wdr41 37
  • 85 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia WDR41 37
  • 86 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia WDR41 37
  • 84 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Wdr41 36
  • 80.89 (n)
  • 84.91 (a)
chicken
(Gallus gallus)
Aves WDR41 36
  • 77.41 (n)
  • 77.85 (a)
WDR41 37
  • 78 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia WDR41 37
  • 72 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.33944 36
zebrafish
(Danio rerio)
Actinopterygii wdr41 36
  • 60.92 (n)
  • 57.72 (a)
wdr41 37
  • 57 (a)
OneToOne
Species with no ortholog for WDR41:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for WDR41 Gene

ENSEMBL:
Gene Tree for WDR41 (if available)
TreeFam:
Gene Tree for WDR41 (if available)

Paralogs for WDR41 Gene

No data available for Paralogs for WDR41 Gene

Variants for WDR41 Gene

Sequence variations from dbSNP and Humsavar for WDR41 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs3149 -- 77,432,611(+) TTTTA(A/C)AATTA utr-variant-3-prime, intron-variant
rs33197 -- 77,448,685(-) TCTCC(A/G)TATTG intron-variant
rs33198 -- 77,493,440(-) ACATT(A/C)TGCCT upstream-variant-2KB
rs33204 - 77,438,259(-) TGCAC(A/G)TTGCC missense, reference, nc-transcript-variant
rs33205 -- 77,438,435(-) TCACA(C/T)GAGGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for WDR41 Gene

Variant ID Type Subtype PubMed ID
nsv820138 CNV Loss 19587683
esv273296 CNV Insertion 20981092
esv270539 CNV Insertion 20981092

Relevant External Links for WDR41 Gene

HapMap Linkage Disequilibrium report
WDR41

Disorders for WDR41 Gene

Relevant External Links for WDR41

Genetic Association Database (GAD)
WDR41
Human Genome Epidemiology (HuGE) Navigator
WDR41
genes like me logo Genes that share disorders with WDR41: view

No data available for UniProtKB/Swiss-Prot for WDR41 Gene

Publications for WDR41 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Discovery and replication of dopamine-related gene effects on caudate volume in young and elderly populations (N=1198) using genome-wide search. (PMID: 21502949) Stein J.L. … Thompson P.M. (Mol. Psychiatry 2011) 3 49
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49

Products for WDR41 Gene

  • Addgene plasmids for WDR41

Sources for WDR41 Gene

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