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Aliases for WDR41 Gene

Aliases for WDR41 Gene

  • WD Repeat Domain 41 2 3 5
  • MSTP048 3

External Ids for WDR41 Gene

Previous GeneCards Identifiers for WDR41 Gene

  • GC05M076813
  • GC05M076763
  • GC05M076721
  • GC05M071934

Summaries for WDR41 Gene

GeneCards Summary for WDR41 Gene

WDR41 (WD Repeat Domain 41) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR41 Gene

Genomics for WDR41 Gene

Regulatory Elements for WDR41 Gene

Enhancers for WDR41 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around WDR41 on UCSC Golden Path with GeneCards custom track

Genomic Location for WDR41 Gene

77,425,970 bp from pter
77,620,611 bp from pter
194,642 bases
Minus strand

Genomic View for WDR41 Gene

Genes around WDR41 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
WDR41 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for WDR41 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WDR41 Gene

Proteins for WDR41 Gene

  • Protein details for WDR41 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    WD repeat-containing protein 41
    Protein Accession:
    Secondary Accessions:
    • B4DT55
    • Q7Z792
    • Q8IWG3
    • Q8IXA9
    • Q8NDA7
    • Q9NV62

    Protein attributes for WDR41 Gene

    459 amino acids
    Molecular mass:
    51728 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAO06948.1; Type=Frameshift; Positions=188; Evidence={ECO:0000305};

    Alternative splice isoforms for WDR41 Gene


neXtProt entry for WDR41 Gene

Proteomics data for WDR41 Gene at MOPED

Post-translational modifications for WDR41 Gene

  • Ubiquitination at Lys 276, Lys 319, and Lys 354
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for WDR41 Gene

Domains & Families for WDR41 Gene

Gene Families for WDR41 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 6 WD repeats.
  • Contains 6 WD repeats.
genes like me logo Genes that share domains with WDR41: view

Function for WDR41 Gene

genes like me logo Genes that share phenotypes with WDR41: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for WDR41 Gene

Localization for WDR41 Gene

Subcellular locations from

Jensen Localization Image for WDR41 Gene COMPARTMENTS Subcellular localization image for WDR41 gene
Compartment Confidence
lysosome 5
vacuole 5
cytosol 3
nucleus 3
golgi apparatus 2
mitochondrion 2
endoplasmic reticulum 1
peroxisome 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for WDR41 Gene

Pathways & Interactions for WDR41 Gene

SuperPathways for WDR41 Gene

No Data Available

Interacting Proteins for WDR41 Gene

Gene Ontology (GO) - Biological Process for WDR41 Gene


No data available for Pathways by source and SIGNOR curated interactions for WDR41 Gene

Drugs & Compounds for WDR41 Gene

No Compound Related Data Available

Transcripts for WDR41 Gene

Unigene Clusters for WDR41 Gene

WD repeat domain 41:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for WDR41 Gene

No ASD Table

Relevant External Links for WDR41 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for WDR41 Gene

mRNA expression in normal human tissues for WDR41 Gene

Protein differential expression in normal tissues from HIPED for WDR41 Gene

This gene is overexpressed in Testis (30.0), Frontal cortex (16.0), and Peripheral blood mononuclear cells (9.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for WDR41 Gene

SOURCE GeneReport for Unigene cluster for WDR41 Gene Hs.482573

genes like me logo Genes that share expression patterns with WDR41: view

Protein tissue co-expression partners for WDR41 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for WDR41 Gene

Orthologs for WDR41 Gene

This gene was present in the common ancestor of chordates.

Orthologs for WDR41 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia WDR41 35
  • 91.21 (n)
  • 89.98 (a)
WDR41 36
  • 90 (a)
(Canis familiaris)
Mammalia WDR41 35
  • 93.03 (n)
  • 92.36 (a)
WDR41 36
  • 91 (a)
(Mus musculus)
Mammalia Wdr41 35
  • 83.26 (n)
  • 85.53 (a)
Wdr41 16
Wdr41 36
  • 85 (a)
(Pan troglodytes)
Mammalia WDR41 35
  • 99.64 (n)
  • 99.35 (a)
WDR41 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Wdr41 35
  • 80.89 (n)
  • 84.91 (a)
(Monodelphis domestica)
Mammalia WDR41 36
  • 86 (a)
(Ornithorhynchus anatinus)
Mammalia WDR41 36
  • 84 (a)
(Gallus gallus)
Aves WDR41 35
  • 77.41 (n)
  • 77.85 (a)
WDR41 36
  • 78 (a)
(Anolis carolinensis)
Reptilia WDR41 36
  • 72 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.33944 35
(Danio rerio)
Actinopterygii wdr41 35
  • 60.92 (n)
  • 57.72 (a)
wdr41 36
  • 57 (a)
Species with no ortholog for WDR41:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for WDR41 Gene

Gene Tree for WDR41 (if available)
Gene Tree for WDR41 (if available)

Paralogs for WDR41 Gene

No data available for Paralogs for WDR41 Gene

Variants for WDR41 Gene

Sequence variations from dbSNP and Humsavar for WDR41 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs33204 - 77,438,259(-) TGCAC(A/G)TTGCC reference, missense
rs389319 - 77,464,795(-) TGCTG(A/G)TGATG reference, missense
rs17751013 - 77,440,917(+) GTTGC(A/G)TTCAT reference, missense
rs722346 -- 77,567,503(+) CTTGA(C/T)CCATG intron-variant
rs3149 -- 77,432,611(+) TTTTA(A/C)AATTA utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for WDR41 Gene

Variant ID Type Subtype PubMed ID
nsv820138 CNV Loss 19587683
esv273296 CNV Insertion 20981092
esv270539 CNV Insertion 20981092

Variation tolerance for WDR41 Gene

Residual Variation Intolerance Score: 87.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.93; 49.09% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for WDR41 Gene

Disorders for WDR41 Gene

Relevant External Links for WDR41

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for WDR41 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for WDR41 Gene

Publications for WDR41 Gene

  1. Discovery and replication of dopamine-related gene effects on caudate volume in young and elderly populations (N=1198) using genome-wide search. (PMID: 21502949) Stein J.L. … Thompson P.M. (Mol. Psychiatry 2011) 3 48 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. (PMID: 26871637) Yang X. … Vidal M. (Cell 2016) 3
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  5. A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. (PMID: 26638075) Gupta G.D. … Pelletier L. (Cell 2015) 3

Products for WDR41 Gene

Sources for WDR41 Gene