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Aliases for WDR38 Gene

Aliases for WDR38 Gene

  • WD Repeat Domain 38 2 3 5

External Ids for WDR38 Gene

Previous GeneCards Identifiers for WDR38 Gene

  • GC09P126657
  • GC09P127615
  • GC09P097229

Summaries for WDR38 Gene

GeneCards Summary for WDR38 Gene

WDR38 (WD Repeat Domain 38) is a Protein Coding gene. An important paralog of this gene is WDR5B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR38 Gene

Genomics for WDR38 Gene

Regulatory Elements for WDR38 Gene

Promoters for WDR38 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around WDR38 on UCSC Golden Path with GeneCards custom track

Genomic Location for WDR38 Gene

Chromosome:
9
Start:
124,853,347 bp from pter
End:
124,857,891 bp from pter
Size:
4,545 bases
Orientation:
Plus strand

Genomic View for WDR38 Gene

Genes around WDR38 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
WDR38 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for WDR38 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WDR38 Gene

Proteins for WDR38 Gene

  • Protein details for WDR38 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5JTN6-WDR38_HUMAN
    Recommended name:
    WD repeat-containing protein 38
    Protein Accession:
    Q5JTN6
    Secondary Accessions:
    • A0PK24

    Protein attributes for WDR38 Gene

    Size:
    314 amino acids
    Molecular mass:
    34312 Da
    Quaternary structure:
    No Data Available

neXtProt entry for WDR38 Gene

Proteomics data for WDR38 Gene at MOPED

Post-translational modifications for WDR38 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for WDR38 Gene

No data available for DME Specific Peptides for WDR38 Gene

Domains & Families for WDR38 Gene

Gene Families for WDR38 Gene

Suggested Antigen Peptide Sequences for WDR38 Gene

Graphical View of Domain Structure for InterPro Entry

Q5JTN6

UniProtKB/Swiss-Prot:

WDR38_HUMAN :
  • Contains 7 WD repeats.
Similarity:
  • Contains 7 WD repeats.
genes like me logo Genes that share domains with WDR38: view

Function for WDR38 Gene

Phenotypes for WDR38 Gene

genes like me logo Genes that share phenotypes with WDR38: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for WDR38 Gene

Localization for WDR38 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for WDR38 Gene COMPARTMENTS Subcellular localization image for WDR38 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for WDR38 Gene

Pathways & Interactions for WDR38 Gene

SuperPathways for WDR38 Gene

No Data Available

Interacting Proteins for WDR38 Gene

Gene Ontology (GO) - Biological Process for WDR38 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for WDR38 Gene

Drugs & Compounds for WDR38 Gene

No Compound Related Data Available

Transcripts for WDR38 Gene

mRNA/cDNA for WDR38 Gene

Unigene Clusters for WDR38 Gene

WD repeat domain 38:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for WDR38 Gene

No ASD Table

Relevant External Links for WDR38 Gene

GeneLoc Exon Structure for
WDR38
ECgene alternative splicing isoforms for
WDR38

Expression for WDR38 Gene

mRNA expression in normal human tissues for WDR38 Gene

mRNA differential expression in normal tissues according to GTEx for WDR38 Gene

This gene is overexpressed in Testis (x11.6), Fallopian Tube (x8.5), Cervix - Endocervix (x7.7), Lung (x6.1), and Brain - Hypothalamus (x4.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for WDR38 Gene



SOURCE GeneReport for Unigene cluster for WDR38 Gene Hs.343383

genes like me logo Genes that share expression patterns with WDR38: view

Protein tissue co-expression partners for WDR38 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for WDR38 Gene

Orthologs for WDR38 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for WDR38 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia WDR38 35
  • 83.9 (n)
  • 80.07 (a)
WDR38 36
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Wdr38 35
  • 78.31 (n)
  • 76.61 (a)
Wdr38 16
Wdr38 36
  • 75 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia WDR38 35
  • 99.15 (n)
  • 98.73 (a)
WDR38 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Wdr38 35
  • 79.11 (n)
  • 75.65 (a)
dog
(Canis familiaris)
Mammalia WDR38 36
  • 75 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia WDR38 36
  • 46 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia wdr38 35
  • 59.6 (n)
  • 53 (a)
zebrafish
(Danio rerio)
Actinopterygii wdr38 35
  • 55.22 (n)
  • 50.51 (a)
wdr38 36
  • 50 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RSA4 36
  • 16 (a)
OneToMany
Species with no ortholog for WDR38:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for WDR38 Gene

ENSEMBL:
Gene Tree for WDR38 (if available)
TreeFam:
Gene Tree for WDR38 (if available)

Paralogs for WDR38 Gene

Paralogs for WDR38 Gene

genes like me logo Genes that share paralogs with WDR38: view

Variants for WDR38 Gene

Sequence variations from dbSNP and Humsavar for WDR38 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs2274970 - 124,856,497(-) AGATG(C/G/T)GTACG reference, missense
rs10760381 - 124,856,560(+) CAGTG(C/G)CAACA reference, missense
rs3814131 -- 124,853,716(-) TACTC(C/T)GGACT intron-variant, upstream-variant-2KB
rs3814132 -- 124,853,697(-) TGAGC(C/T)ACTGC intron-variant, upstream-variant-2KB
rs4837002 -- 124,851,890(+) ACAAG(G/T)TCTAC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for WDR38 Gene

Variant ID Type Subtype PubMed ID
nsv831721 CNV Gain 17160897

Variation tolerance for WDR38 Gene

Residual Variation Intolerance Score: 89.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.27; 70.26% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for WDR38 Gene

HapMap Linkage Disequilibrium report
WDR38

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WDR38 Gene

Disorders for WDR38 Gene

Relevant External Links for WDR38

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
WDR38

No disorders were found for WDR38 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for WDR38 Gene

Publications for WDR38 Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for WDR38 Gene

Sources for WDR38 Gene

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