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Aliases for WDR38 Gene

Aliases for WDR38 Gene

  • WD Repeat Domain 38 2 3 5

External Ids for WDR38 Gene

Previous GeneCards Identifiers for WDR38 Gene

  • GC09P126657
  • GC09P127615
  • GC09P097229

Summaries for WDR38 Gene

GeneCards Summary for WDR38 Gene

WDR38 (WD Repeat Domain 38) is a Protein Coding gene. An important paralog of this gene is DAW1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR38 Gene

Genomics for WDR38 Gene

Regulatory Elements for WDR38 Gene

Enhancers for WDR38 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09F124772 0.4 ENCODE 13.6 -80.7 -80741 0.1 ELF1 WDR38 RPL35 ARPC5L NR6A1 OLFML2A
GH09F124769 1.2 ENCODE 13.6 -82.7 -82730 3.4 HDGF ARNT CREB3L1 MLX WRNIP1 ARID4B SIN3A FEZF1 YY1 ZNF207 GOLGA1 WDR38 ARPC5L RPL35 MIR181A2HG ENSG00000236643 NR6A1
GH09F124774 0.8 Ensembl ENCODE 13.6 -78.7 -78685 0.7 ELF3 ATF1 KLF17 ARID4B ZNF2 RAD21 RFX5 ZNF366 ZNF143 RCOR1 WDR38 RPL35 ARPC5L MIR181A2HG NR6A1 OLFML2A
GH09F124894 1.1 ENCODE 12.2 +41.4 41440 0.2 HDGF CTCF ZNF654 WRNIP1 BHLHE40 CEBPB TRIM22 RAD21 TEAD3 SMC3 ARPC5L RPL35 WDR38 RABEPK RPSAP76 GC09M124888 RNU4-82P GC09P124941
GH09F124897 1.2 ENCODE 12.2 +44.5 44538 1.0 TBP RARA CREM MIXL1 THAP11 CEBPB KAT8 ATF4 MIER3 KLF16 ARPC5L RPL35 WDR38 RPSAP76 RABEPK GOLGA1 GC09M124888 RNU4-82P GC09P124941
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around WDR38 on UCSC Golden Path with GeneCards custom track

Promoters for WDR38 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001314210 53 801 ATF1 PKNOX1 CREB3L1 ARID4B SIN3A ZNF48 ZNF2 GLIS2 ZNF143 ZNF207

Genomic Location for WDR38 Gene

124,853,347 bp from pter
124,857,891 bp from pter
4,545 bases
Plus strand

Genomic View for WDR38 Gene

Genes around WDR38 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
WDR38 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for WDR38 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WDR38 Gene

Proteins for WDR38 Gene

  • Protein details for WDR38 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    WD repeat-containing protein 38
    Protein Accession:
    Secondary Accessions:
    • A0PK24

    Protein attributes for WDR38 Gene

    314 amino acids
    Molecular mass:
    34312 Da
    Quaternary structure:
    No Data Available

neXtProt entry for WDR38 Gene

Post-translational modifications for WDR38 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for WDR38 Gene

No data available for DME Specific Peptides for WDR38 Gene

Domains & Families for WDR38 Gene

Gene Families for WDR38 Gene

Suggested Antigen Peptide Sequences for WDR38 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 7 WD repeats.
  • Contains 7 WD repeats.
genes like me logo Genes that share domains with WDR38: view

Function for WDR38 Gene

genes like me logo Genes that share phenotypes with WDR38: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for WDR38 Gene

Localization for WDR38 Gene

Subcellular locations from

Jensen Localization Image for WDR38 Gene COMPARTMENTS Subcellular localization image for WDR38 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for WDR38 Gene

Pathways & Interactions for WDR38 Gene

SuperPathways for WDR38 Gene

No Data Available

Interacting Proteins for WDR38 Gene

Gene Ontology (GO) - Biological Process for WDR38 Gene


No data available for Pathways by source and SIGNOR curated interactions for WDR38 Gene

Transcripts for WDR38 Gene

mRNA/cDNA for WDR38 Gene

Unigene Clusters for WDR38 Gene

WD repeat domain 38:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for WDR38 Gene

No ASD Table

Relevant External Links for WDR38 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for WDR38 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for WDR38 Gene

mRNA differential expression in normal tissues according to GTEx for WDR38 Gene

This gene is overexpressed in Testis (x11.6), Fallopian Tube (x8.5), Cervix - Endocervix (x7.7), Lung (x6.1), and Brain - Hypothalamus (x4.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for WDR38 Gene

Protein tissue co-expression partners for WDR38 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of WDR38 Gene:


SOURCE GeneReport for Unigene cluster for WDR38 Gene:

genes like me logo Genes that share expression patterns with WDR38: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for WDR38 Gene

Orthologs for WDR38 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for WDR38 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia WDR38 34 35
  • 99.15 (n)
(Bos Taurus)
Mammalia WDR38 34 35
  • 83.9 (n)
(Rattus norvegicus)
Mammalia Wdr38 34
  • 79.11 (n)
(Mus musculus)
Mammalia Wdr38 34 16 35
  • 78.31 (n)
(Canis familiaris)
Mammalia WDR38 35
  • 75 (a)
(Monodelphis domestica)
Mammalia WDR38 35
  • 46 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia wdr38 34
  • 59.6 (n)
(Danio rerio)
Actinopterygii wdr38 34 35
  • 55.22 (n)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RSA4 35
  • 16 (a)
Species where no ortholog for WDR38 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for WDR38 Gene

Gene Tree for WDR38 (if available)
Gene Tree for WDR38 (if available)

Paralogs for WDR38 Gene

Paralogs for WDR38 Gene

genes like me logo Genes that share paralogs with WDR38: view

Variants for WDR38 Gene

Sequence variations from dbSNP and Humsavar for WDR38 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs10533023 -- 124,854,515(+) ACACA(-/AC)TACAT intron-variant
rs10593927 -- 124,858,202(+) CACAC(-/AT)GTCAC intron-variant, downstream-variant-500B
rs10760379 -- 124,852,953(+) ATCCT(C/T)AACCT upstream-variant-2KB
rs10760380 -- 124,854,044(+) GACTC(C/G)AGAGA intron-variant
rs10760381 -- 124,856,560(+) CAGTG(C/G)CAACA reference, missense

Structural Variations from Database of Genomic Variants (DGV) for WDR38 Gene

Variant ID Type Subtype PubMed ID
nsv831721 CNV gain 17160897
nsv951760 CNV deletion 24416366

Variation tolerance for WDR38 Gene

Residual Variation Intolerance Score: 89.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.27; 70.26% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for WDR38 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WDR38 Gene

Disorders for WDR38 Gene

Relevant External Links for WDR38

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for WDR38 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for WDR38 Gene

Publications for WDR38 Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for WDR38 Gene

Sources for WDR38 Gene

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