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Aliases for WDR38 Gene

Aliases for WDR38 Gene

  • WD Repeat Domain 38 2 3 5

External Ids for WDR38 Gene

Previous GeneCards Identifiers for WDR38 Gene

  • GC09P126657
  • GC09P127615
  • GC09P097229

Summaries for WDR38 Gene

GeneCards Summary for WDR38 Gene

WDR38 (WD Repeat Domain 38) is a Protein Coding gene. An important paralog of this gene is DAW1.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR38 Gene

Genomics for WDR38 Gene

Regulatory Elements for WDR38 Gene

Enhancers for WDR38 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09G124799 1.5 Ensembl ENCODE dbSUPER 12.1 -52.0 -52034 3.3 PKNOX1 SIN3A ZBTB7B GLIS2 ZNF766 GATA2 FOS KDM4B DEK ZNF263 WDR38 RPL35 ARPC5L OLFML2A GAPVD1 RNU6-1020P MIR181A2HG PIR55692
GH09G124795 1.4 Ensembl ENCODE dbSUPER 12.1 -56.6 -56601 3.5 ELF3 PKNOX1 FOXA2 SREBF2 ARID4B ZNF48 ZSCAN9 RAD21 RARA ZNF121 WDR38 RPL35 ARPC5L GAPVD1 RNU6-1020P MIR181A2HG PIR55692 OLFML2A
GH09G124768 1.2 ENCODE 13.6 -82.7 -82730 3.4 MLX CREB3L1 AGO1 FEZF1 YY1 ZNF143 ZNF263 SP3 NFYC TBX21 WDR38 ARPC5L RPL35 MIR181A2HG ENSG00000236643 NR6A1
GH09G124774 1.1 Ensembl ENCODE 13.6 -78.7 -78685 0.7 ELF3 ATF1 RB1 ARID4B KLF17 ZNF2 RAD21 RFX5 ZNF366 ZNF143 WDR38 RPL35 ARPC5L MIR181A2HG OLFML2A NR6A1
GH09G124756 1.2 Ensembl ENCODE 11.8 -93.9 -93870 5.4 PKNOX1 ARNT SIN3A TCF12 ZNF766 GATA2 CBX5 FOS JUNB SMARCB1 WDR38 RPL35 ARPC5L MIR181A2HG ENSG00000236643 GC09P124694
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around WDR38 on UCSC Golden Path with GeneCards custom track

Promoters for WDR38 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000241357 -47 601 PKNOX1 ATF1 AGO1 ARID4B SIN3A ZNF2 ZNF48 ZBTB7B GLIS2 ZNF143

Genomic Location for WDR38 Gene

124,853,347 bp from pter
124,857,891 bp from pter
4,545 bases
Plus strand

Genomic View for WDR38 Gene

Genes around WDR38 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
WDR38 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for WDR38 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WDR38 Gene

Proteins for WDR38 Gene

  • Protein details for WDR38 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    WD repeat-containing protein 38
    Protein Accession:
    Secondary Accessions:
    • A0PK24

    Protein attributes for WDR38 Gene

    314 amino acids
    Molecular mass:
    34312 Da
    Quaternary structure:
    No Data Available

neXtProt entry for WDR38 Gene

Post-translational modifications for WDR38 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for WDR38 Gene

No data available for DME Specific Peptides for WDR38 Gene

Domains & Families for WDR38 Gene

Gene Families for WDR38 Gene

Suggested Antigen Peptide Sequences for WDR38 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with WDR38: view

No data available for UniProtKB/Swiss-Prot for WDR38 Gene

Function for WDR38 Gene

genes like me logo Genes that share phenotypes with WDR38: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for WDR38 Gene

Localization for WDR38 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for WDR38 gene
Compartment Confidence
nucleus 2
cytosol 2
extracellular 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for WDR38 Gene

Pathways & Interactions for WDR38 Gene

SuperPathways for WDR38 Gene

No Data Available

Interacting Proteins for WDR38 Gene

Gene Ontology (GO) - Biological Process for WDR38 Gene


No data available for Pathways by source and SIGNOR curated interactions for WDR38 Gene

Drugs & Compounds for WDR38 Gene

No Compound Related Data Available

Transcripts for WDR38 Gene

mRNA/cDNA for WDR38 Gene

Unigene Clusters for WDR38 Gene

WD repeat domain 38:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for WDR38 Gene

No ASD Table

Relevant External Links for WDR38 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for WDR38 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for WDR38 Gene

mRNA differential expression in normal tissues according to GTEx for WDR38 Gene

This gene is overexpressed in Testis (x11.6), Fallopian Tube (x8.5), Cervix - Endocervix (x7.7), Lung (x6.1), and Brain - Hypothalamus (x4.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for WDR38 Gene

Protein tissue co-expression partners for WDR38 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of WDR38 Gene:


SOURCE GeneReport for Unigene cluster for WDR38 Gene:

genes like me logo Genes that share expression patterns with WDR38: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for WDR38 Gene

Orthologs for WDR38 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for WDR38 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia WDR38 35 34
  • 99.15 (n)
(Bos Taurus)
Mammalia WDR38 34 35
  • 83.9 (n)
(Rattus norvegicus)
Mammalia Wdr38 34
  • 79.11 (n)
(Mus musculus)
Mammalia Wdr38 34 16 35
  • 78.31 (n)
(Canis familiaris)
Mammalia WDR38 35
  • 75 (a)
(Monodelphis domestica)
Mammalia WDR38 35
  • 46 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia wdr38 34
  • 59.6 (n)
(Danio rerio)
Actinopterygii wdr38 34 35
  • 55.22 (n)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RSA4 35
  • 16 (a)
Species where no ortholog for WDR38 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for WDR38 Gene

Gene Tree for WDR38 (if available)
Gene Tree for WDR38 (if available)

Paralogs for WDR38 Gene

Paralogs for WDR38 Gene

genes like me logo Genes that share paralogs with WDR38: view

Variants for WDR38 Gene

Sequence variations from dbSNP and Humsavar for WDR38 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1001774536 -- 124,857,230(+) GTGGA(A/G)GTAGG intron-variant
rs1002575809 -- 124,852,809(+) CCTCA(A/G)ATGGC upstream-variant-2KB
rs1002772779 -- 124,856,020(+) ATGTC(A/T)CCAGT intron-variant
rs1003489784 -- 124,853,513(+) GGGGC(A/G)GGGCG utr-variant-5-prime
rs1003695555 -- 124,852,009(+) GGGTT(-/G)GGGGG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for WDR38 Gene

Variant ID Type Subtype PubMed ID
nsv831721 CNV gain 17160897
nsv951760 CNV deletion 24416366

Variation tolerance for WDR38 Gene

Residual Variation Intolerance Score: 89.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.27; 70.26% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for WDR38 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WDR38 Gene

Disorders for WDR38 Gene

Relevant External Links for WDR38

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for WDR38 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for WDR38 Gene

Publications for WDR38 Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for WDR38 Gene

Sources for WDR38 Gene

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