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WDR37 Gene

protein-coding   GIFtS: 53
GCID: GC10P001095

WD Repeat Domain 37

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
WD Repeat Domain 371 2
WD Repeat-Containing Protein 372
KIAA09823

External Ids:    HGNC: 314061   Entrez Gene: 228842   Ensembl: ENSG000000470567   UniProtKB: Q9Y2I83   

Export aliases for WDR37 gene to outside databases

Previous GC identifers: GC10P001056 GC10P001085 GC10P001092 GC10P001041


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for WDR37 Gene:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of
approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation
of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular
processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. (provided by
RefSeq, Jul 2008)

GeneCards Summary for WDR37 Gene:
WDR37 (WD repeat domain 37) is a protein-coding gene. An important paralog of this gene is WDR12.

Gene Wiki entry for WDR37 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NC_018921.2  NT_008705.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the WDR37 gene promoter:
         Elk-1   LHX3b/Lhx3b   CUTL1   NF-kappaB   NF-kappaB2   LHX3a/Lhx3a   aMEF-2   NF-kappaB1   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidWDR37 promoter sequence
   Search Chromatin IP Primers for WDR37

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat WDR37


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10p15.3   Ensembl cytogenetic band:  10p15.3   HGNC cytogenetic band: 10p15.3

WDR37 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WDR37 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P001095:  view genomic region     (about GC identifiers)

Start:
1,095,478 bp from pter      End:
1,178,237 bp from pter
Size:
82,760 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: WDR37_HUMAN, Q9Y2I8 (See protein sequence)
Recommended Name: WD repeat-containing protein 37  
Size: 494 amino acids; 54665 Da
Sequence caution: Sequence=BAA76826.2; Type=Erroneous initiation;
Secondary accessions: D3DRQ7 Q5SW03 Q9NTJ6

Explore the universe of human proteins at neXtProt for WDR37: NX_Q9Y2I8

Explore proteomics data for WDR37 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See WDR37 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_054742.2  
    ENSEMBL proteins: 
     ENSP00000350954   ENSP00000370730   ENSP00000263150   ENSP00000404346  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    WDR: WD repeat domain containing

    5 InterPro protein domains:
     IPR019775 WD40_repeat_CS
     IPR001680 WD40_repeat
     IPR020472 G-protein_beta_WD-40_rep
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q9Y2I8

    ProtoNet protein and cluster: Q9Y2I8

    UniProtKB/Swiss-Prot: WDR37_HUMAN, Q9Y2I8
    Similarity: Contains 7 WD repeats


    Find genes that share domains with WDR37           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with WDR37           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for WDR37:
     Increased S DNA content  Increased number of mitotic ce  Synthetic lethal with Ras 

         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Wdr37):
     behavior/neurological  hematopoietic system  homeostasis/metabolism  immune system  integument 

    Find genes that share phenotypes with WDR37           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for WDR37
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for WDR37
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for WDR37

    miRNA
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    miRTarBase miRNAs that target WDR37:
    hsa-mir-141-3p (MIRT021662), hsa-mir-92a-3p (MIRT049462), hsa-mir-200c-3p (MIRT021071), hsa-mir-744-5p (MIRT037566), hsa-mir-200a-3p (MIRT020348), hsa-mir-429 (MIRT016638), hsa-mir-200b-3p (MIRT024126), hsa-mir-30b-5p (MIRT046141)

    Block miRNA regulation of human, mouse, rat WDR37 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate WDR37 (see all 97):
    hsa-miR-579 hsa-miR-520e hsa-miR-520f hsa-miR-106a hsa-miR-4267 hsa-miR-10b* hsa-miR-93 hsa-miR-92b
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    Predesigned siRNA for gene silencing in human, mouse, rat WDR37

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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR37

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR37


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus2
    cytoskeleton1
    cytosol1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for WDR37
    Interactions:

        Search GeneGlobe Interaction Network for WDR37

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for WDR37 (Q9Y2I82, 3 ENSP000002631504) via UniProtKB, MINT, STRING, and/or I2D (see all 18)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SFNP319472, 3MINT-3976543 I2D: score=1 
    EWSR1Q018443, ENSP000003810314I2D: score=2 STRING: ENSP00000381031
    RELQ048643, ENSP000002950254I2D: score=1 STRING: ENSP00000295025
    TSC22D4Q9Y3Q83I2D: score=1 
    YWHAEP622583I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for WDR37



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for WDR37 gene: 
    NM_014023.3  

    Unigene Cluster for WDR37:

    WD repeat domain 37
    Hs.188495  [show with all ESTs]
    Unigene Representative Sequence: NM_014023
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000358220(uc001igf.1 uc009xhm.1 uc009xhn.1 uc001igg.1)
    ENST00000381329(uc001ige.3) ENST00000263150 ENST00000436154 ENST00000482165

    miRNA
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    Block miRNA regulation of human, mouse, rat WDR37 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate WDR37 (see all 97):
    hsa-miR-579 hsa-miR-520e hsa-miR-520f hsa-miR-106a hsa-miR-4267 hsa-miR-10b* hsa-miR-93 hsa-miR-92b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat WDR37
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    GenScript: all cDNA clones in your preferred vector: WDR37 (NM_014023)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR37
    Primer
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    OriGene qPCR primer pairs and template standards for WDR37
    OriGene qSTAR qPCR primer pairs in human, mouse for WDR37
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat WDR37
      QuantiTect SYBR Green Assays in human, mouse, rat WDR37
      QuantiFast Probe-based Assays in human, mouse, rat WDR37

    Additional mRNA sequence: 

    AB023199.1 AK024605.1 AK292591.1 AK307259.1 AL136827.1 BC018044.1 BC018045.1 BC046195.1 
    BC046483.1 BC050720.2 

    20 DOTS entries:

    DT.100744756  DT.121257305  DT.92423348  DT.453773  DT.97817348  DT.97838100  DT.101961628  DT.408305 
    DT.99954241  DT.91953431  DT.95073110  DT.101957837  DT.121257197  DT.121257335  DT.86843284  DT.95328649 
    DT.97815776  DT.91888552  DT.91892985  DT.95255026 

    Selected AceView cDNA sequences (see all 126):

    CA976047 F06159 AA017342 AA700843 AI671988 NM_014023 AI131459 CB216081 
    AI421861 CK822348 AW592361 Z38858 AI422844 AW295951 C01597 BM667332 
    Z42698 Z39075 AK024605 AI862319 AL136827 BE669681 C18387 BE551396 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for WDR37 (see all 12)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b · 3c · 3d · 3e · 3f ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^
    SP1:        -     -     -     -     -     -     -                 -     -     -           -                                                     -     -     -   
    SP2:              -     -     -     -     -     -                 -     -     -           -                                                                     
    SP3:                                                              -           -           -                                                                     
    SP4:                                                              -     -     -           -                                                                     
    SP5:                                                                                                                                            -     -     -   

    ExUns: 15a · 15b ^ 16a · 16b ^ 17a · 17b ^ 18a · 18b · 18c ^ 19
    SP1:                          -                                 
    SP2:                                                            
    SP3:                                                            
    SP4:                                                            
    SP5:                          -                                 


    ECgene alternative splicing isoforms for WDR37

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    WDR37 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTTGCTTTG
    WDR37 Expression
    About this image


    WDR37 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Ovarian Mesenchymal Stroma Cells Ovary Interstitium
             Oviduct
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Limb (Muscoskeletal System)
             Prechondrocytic Mesenchymal Cells Zeugopod
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    WDR37 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    WDR37 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.188495
        Custom PCR Arrays for WDR37
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    QuantiFast Probe-based Assays in human, mouse, rat WDR37
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR37

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for WDR37 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Wdr371 , 5 WD repeat domain 371, 5 87.92(n)1
    96.96(a)1
      13 (3.60 cM)5
    2076151  NM_001039388.21  NP_001034477.11 
     88029955 
    chicken
    (Gallus gallus)
    Aves WDR371 WD repeat domain 37 79.28(n)
    93.93(a)
      420460  XM_418562.3  XP_418562.2 
    lizard
    (Anolis carolinensis)
    Reptilia WDR376
    WD repeat domain 37
    93(a)
    1 ↔ 1
    6(8123987-8167517)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia wdr371 WD repeat domain 37 76.79(n)
    91.5(a)
      100125083  NM_001102995.1  NP_001096465.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.72212 Transcribed sequence with moderate similarity to protein more 76.45(n)    CD751169.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG123331 CG12333 57.68(n)
    57.04(a)
      42218  NM_142466.3  NP_650723.1 
    worm
    (Caenorhabditis elegans)
    Secernentea C05D2.101 C05D2.10 51.71(n)
    48.29(a)
      175774  NM_065803.3  NP_498204.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YTM16
    Constituent of 66S pre-ribosomal particles, forms ...
    19(a)
    1 → many
    XV(832813-834195) YOR272W


    ENSEMBL Gene Tree for WDR37 (if available)
    TreeFam Gene Tree for WDR37 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for WDR37 gene
    WDR122  
    1 SIMAP similar gene for WDR37 using alignment to 4 protein entries:     WDR37_HUMAN (see all proteins):
    PF20

    Find genes that share paralogs with WDR37           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for WDR37 (see all 1877)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1175526001,2
    F--1100852(+) GGACAT/AGGAAA 1 -- us2k11Minor allele frequency- A:0.01NA 120
    rs1451122011,2
    --1100913(+) TAGACA/GCTGAG 1 -- us2k10--------
    rs1404584511,2
    --1101092(+) TGATGC/TCAGCC 1 -- us2k10--------
    rs1824297371,2
    --1101190(+) TTTTAC/GTTTAT 1 -- us2k10--------
    rs727609291,2
    --1101210(+) TTGGGA/GATTAA 1 -- us2k10--------
    rs1442063951,2
    --1101312(+) CTTTTA/GTGGAA 1 -- us2k10--------
    rs1113886721,2
    C,F--1101347(+) TTACAT/ATAGCG 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs43738451,2
    C,H--1101389(+) TCCAGC/AAAAAT 1 -- us2k116Minor allele frequency- A:0.00NS EA NA WA CSA 792
    rs109033571,2
    C,F,A,H--1101535(+) CTCTAA/CAAGTT 1 -- us2k116Minor allele frequency- C:0.14NS EA NA WA 2326
    rs1932792661,2
    --1101620(+) AAGTTG/TTATTA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for WDR37 (1095478 - 1178237 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for WDR37 (see all 14):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2660097CNV Deletion23128226
    esv2729439CNV Deletion23290073
    esv2662183CNV Deletion23128226
    esv2729406CNV Deletion23290073
    esv2573324CNV Deletion19546169
    esv1356116CNV Deletion17803354
    esv1009406CNV Deletion20482838
    esv2729417CNV Deletion23290073
    esv2729428CNV Deletion23290073
    dgv590n71CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with WDR37           About GenesLikeMe

    Genetic Association Database (GAD): WDR37
    Human Genome Epidemiology (HuGE) Navigator: WDR37 (6 documents)

    Export disorders for WDR37 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for WDR37 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with WDR37)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (Genome Res. 2001)
    2. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 1999)
    3. Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. (PubMed id 19851296)1, 4 Oguri M....Yamada Y. (Am. J. Hypertens. 2010)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    5. An approach based on a genome-wide association study reveals candidate loci for narcolepsy. (PubMed id 20677014)1, 4 Shimada M....Tokunaga K. (Hum. Genet. 2010)
    6. Association of genetic variants with hemorrhagic stroke in Japanese individuals. (PubMed id 20198315)1, 4 Yoshida T....Yamada Y. (Int. J. Mol. Med. 2010)
    7. New loci associated with kidney function and chronic kidney disease. (PubMed id 20383146)1, 4 KAPttgen A....Fox C.S. (Nat. Genet. 2010)
    8. Association of gene polymorphisms with chronic kidney disease in Japanese individuals. (PubMed id 19724895)1, 4 Yoshida T....Yamada Y. (Int. J. Mol. Med. 2009)
    9. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)
    10. Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans. (PubMed id 23400010)1 Del-Aguila J.L....Boerwinkle E. (Pharmacogenomics J. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 22884 HGNC: 31406 AceView: WDR37 Ensembl:ENSG00000047056 euGenes: HUgn22884
    ECgene: WDR37 H-InvDB: WDR37

    (According to HUGE)
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    HUGE: KIAA0982

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for WDR37 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for WDR37 gene:
    Search GeneIP for patents involving WDR37

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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