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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

WDR36 Gene

protein-coding   GIFtS: 54
GCID: GC05P110427

WD repeat domain 36

(Previous names: glaucoma 1, open angle, G )
(Previous symbol: GLC1G)
 Explore 13 diseases affiliated with
WDR36 via our new
 Human Malady Compendium 
Biological research products
for WDR36
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
WD Repeat Domain 361 2     TAWDRP2 5
TA-WDRP1 2 3     Glaucoma 1, Open Angle, G1
GLC1G1 2 5     T-Cell Activation WD Repeat Protein2
UTP211 2     WD Repeat-Containing Protein 362
T-Cell Activation WD Repeat-Containing Protein2 3     

External Ids:    HGNC: 306961   Entrez Gene: 1344302   Ensembl: ENSG000001349877   OMIM: 6096695   UniProtKB: Q8NI363   

Export aliases for WDR36 gene to outside databases

Previous GC identifers: GC05P110505 GC05P110455 GC05P105606


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for WDR36:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately
40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or
multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle
progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with
adult-onset primary open-angle glaucoma (POAG). (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: WDR36_HUMAN, Q8NI36
Function: Involved in T-cell activation and highly co-regulated with IL2

Gene Wiki entry for WDR36


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.1  NT_034772.6  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the WDR36 gene promoter:
         POU3F2 (N-Oct-5b)   STAT5A   Egr-2   MEF-2A   POU2F1   POU2F1a   SEF-1 (1)   aMEF-2   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidWDR36 promoter sequence
   Search SABiosciences Chromatin IP Primers for WDR36

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WDR36


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q22.1   Ensembl cytogenetic band:  5q22.1   HGNC cytogenetic band: 5q22.2

WDR36 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WDR36 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P110427:  view genomic region     (about GC identifiers)

Start:
110,427,414 bp from pter      End:
110,466,200 bp from pter
Size:
38,787 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: WDR36_HUMAN, Q8NI36 (See protein sequence)
Recommended Name: WD repeat-containing protein 36  
Size: 951 amino acids; 105322 Da
Subcellular location: Nucleus, nucleolus
Sequence caution: Sequence=BAC04527.1; Type=Erroneous initiation;
Secondary accessions: A2RUS4 Q8N1Q2

Explore the universe of human proteins at neXtProt for WDR36: NX_Q8NI36

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8NI36

  • WDR36 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_644810.1  
    ENSEMBL proteins: 
     ENSP00000423067   ENSP00000424628   ENSP00000422158   ENSP00000426509  

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    Uscn Proteins for WDR36

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005730nucleolus IEA--
    GO:0032040small-subunit processome IEA--


    WDR36 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    WDR36 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR019775 WD40_repeat_CS
     IPR001680 WD40_repeat
     IPR007319 SSU_processome_Utp21
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q8NI36

    ProtoNet protein and cluster: Q8NI36

    1 Blocks protein family: IPB000873 AMP-binding signature

    UniProtKB/Swiss-Prot: WDR36_HUMAN, Q8NI36
    Similarity: Contains 9 WD repeats


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: WDR36_HUMAN, Q8NI36
    Function: Involved in T-cell activation and highly co-regulated with IL2

    miRNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR36

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--


    WDR36 for ontologies           About GeneDecksing


    5 GenomeRNAi human phenotypes for WDR36:
     Decreased homologous recombina  Increased gamma-H2AX phosphory  Nuclear 40S maturation defects  Nucleolar pre-40S maturation d 
     Synthetic lethal with Ras 

    Animal Models:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Wdr36):
     embryogenesis  mortality/aging 

    WDR36 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Ribosome biogenesis in eukaryotes
    Ribosome biogenesis in eukaryotes1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways



    1         Kegg Pathway  (Kegg details for WDR36):
        Ribosome biogenesis in eukaryotes


    WDR36 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for WDR36

    5/94 Interacting proteins for WDR36 (Q8NI363) via UniProtKB, MINT, STRING, and/or I2D (see all 94)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006364rRNA processing IEA--
    GO:0007601visual perception IEA--
    GO:0008150biological_process ND--
    GO:0050896response to stimulus IEA--


    WDR36 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for WDR36
    Search CenterWatch for drugs/clinical trials and news about WDR36 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for WDR36 gene: 
    NM_139281.2  

    Unigene Cluster for WDR36:

    WD repeat domain 36
    Hs.533237  [show with all ESTs]
    Unigene Representative Sequence: NM_139281
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000506538(uc003kpd.3 uc010jbu.3) ENST00000513710 ENST00000505303
    ENST00000515784 ENST00000504122

    miRNA
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    8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate WDR36 (see all 11):
    hsa-miR-498 hsa-miR-607 hsa-miR-130a* hsa-miR-23c hsa-miR-3647-3p hsa-miR-23b hsa-miR-3613-3p hsa-miR-205*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Clone
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDR36
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR36

    Additional cDNA sequence: 

    AF385437.1 AK055664.1 AK074202.1 AK095312.1 AL832494.1 BC037427.1 BC133025.1 BC136517.1 
    CR749211.1 

    6 DOTS entries:

    DT.100024414  DT.95266600  DT.441426  DT.120828713  DT.102830676  DT.40122924 

    24/154 AceView cDNA sequences (see all 154):

    AA768963 AI452987 CB243764 AK095312 BM129741 AI695924 BQ420958 BQ218703 
    CA438568 CD514861 CD636847 AA442593 BP365899 BQ231864 AA057286 BX110480 
    CA429633 NM_139281 BF056935 BX112836 N28000 AF385437 AK055664 AA039378 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for WDR36    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23a · 23b
    SP1:              -                                                                                                                                             
    SP2:        -     -                                                                                                                       -                     
    SP3:                                                                                                                                                            


    ECgene alternative splicing isoforms for WDR36

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    WDR36 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GTGTCTGTTT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See WDR36 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for WDR36

    SOURCE GeneReport for Unigene cluster: Hs.533237

    UniProtKB/Swiss-Prot: WDR36_HUMAN, Q8NI36
    Tissue specificity: Expressed in heart, placenta, liver, skeletal muscle, kidney and pancreas. In ocular tissues,
    strong expression in iris, sclera, ciliary muscle, ciliary body, retina and optic nerve

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for WDR36 gene from 10/34 species (see all 34)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Wdr361 , 5 WD repeat domain 361, 5 86.77(n)1
    88.85(a)1
      18 (18.13 cM)5
    2253481  NM_001110015.11  NP_001103485.11 
     328372255 
    chicken
    (Gallus gallus)
    Aves WDR361 WD repeat domain 36 73.25(n)
    73.93(a)
      415609  NM_001044634.1  NP_001038099.1 
    lizard
    (Anolis carolinensis)
    Reptilia WDR366
    --
    72(a)
    1 ↔ 1
    GL343193.1(6226867-6277140)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC531822 similar to T-cell activation WD repeat protein 74.61(n)    BC047972.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb33e102 wufb33e10 75.16(n)   321745  BC057514.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG97991 CG9799 48.3(n)
    40.5(a)
      41647  NM_142027.3  NP_650284.2 
    worm
    (Caenorhabditis elegans)
    Secernentea Y45F10D.76
    --
    28(a)
    1 ↔ 1
    IV(13788911-13796199)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes UTP211 Utp21p 46.29(n)
    34.42(a)
      851125   NP_013513.3 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G049401 transducin/WD40 domain-containing protein 48.44(n)
    39.77(a)
      825833  NM_116732.2  NP_567275.1 
    rice
    (Oryza sativa)
    Liliopsida --
    WD repeat-containing protein, putative, expressed
    34(a)
    1 ↔ 1
    6(26302840-26311415)


    ENSEMBL Gene Tree for WDR36 (if available)
    TreeFam Gene Tree for WDR36 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/859 NCBI SNPs in WDR36 are shown (see all 859    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs345952521,2
    C,F,pathogenic162319635(-) AGCAGT/CCTATA 2 /D /G mis14Minor allele frequency- C:0.01NA EU 5945
    rs1165298821,2
    C,F,pathogenic162328382(+) ACATCG/AAGGAA 2 /Q /R mis13Minor allele frequency- A:0.00NA EU 5983
    rs1182040221,2
    Cpathogenic162334320(+) TGACAA/GTGCTC 2 N S mis11Minor allele frequency- G:0.00NA 4496
    rs100455771,2
    C,--105605508(+) cggtgC/Tgcgca 1 -- us2k10--------
    rs1115323121,2
    C,--105605611(+) CTCACA/GCTGGG 1 -- us2k10--------
    rs98855721,2
    C,F,--105605725(+) TTTAAG/ATCATA 1 -- us2k14Minor allele frequency- A:0.15NA WA 124
    rs764536151,2
    C,--105606036(+) GTAGAG/CACAGA 1 -- us2k12Minor allele frequency- C:0.12CSA WA 120
    rs794659051,2
    C,F,--105606064(+) AAGTAC/AATTTA 1 -- us2k11Minor allele frequency- A:0.05WA 118
    rs100506521,2
    C,F,--105606070(+) ATTTAC/GATTAG 1 -- us2k1 tfbs34Minor allele frequency- G:0.11NA WA 124
    rs772989711,2
    C,--105606380(+) CTAAGA/GCACTC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for WDR36 (110427414 - 110466200 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for WDR36
         2 CNVs: 51524 34442
    Human Gene Mutation Database (HGMD): WDR36

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing WDR36
    DNA2.0 Custom Variant and Variant Library Synthesis for WDR36

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    WDR36 for disorders           About GeneDecksing

    OMIM gene information: 609669   
    OMIM disorders: 609887  
    UniProtKB/Swiss-Prot: WDR36_HUMAN, Q8NI36
  • Defects in WDR36 are the cause of primary open angle glaucoma type 1G (GLC1G) [MIM:609887]. Primary open angle
  • glaucoma (POAG) is characterized by a specific pattern of optic nerve and visual field defects. The angle of the
    anterior chamber of the eye is open, and usually the intraocular pressure is increased. The disease is asymptomatic
    until the late stages, by which time significant and irreversible optic nerve damage has already taken place

    13 diseases for WDR36:    About MalaCards
    open-angle glaucoma    glaucoma 1, open angle, g    primary open angle glaucoma    glaucoma
    primary open anle glaucoma    primary congenital glaucoma    myocardial infarction    polyposis
    blindness    asthma    obesity    esophagitis
    malaria

    2 diseases from the University of Copenhagen DISEASES database for WDR36:
    Glaucoma     Blindness

    2 Novoseek disease relationships for WDR36 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    glaucoma open-angle 85.1 10 16723468 (2), 19347049 (2), 17960130 (2), 16966629 (2) (see all 6)
    glaucoma 74.8 9 16876519 (2), 16723468 (1), 16877390 (1), 17563717 (1) (see all 6)

    Human Genome Epidemiology (HuGE) Navigator: WDR36 (14 documents)

    Export disorders for WDR36 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for WDR36 gene, integrated from 9 sources (see all 46):
    (articles sorted by number of sources associating them with WDR36)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of a novel adult-onset primary open-angle glaucoma (POAG) gene on 5q22.1. (PubMed id 15677485)1, 2, 3, 9 Monemi S.... Sarfarazi M. (2005)
    2. The small-subunit processome is a ribosome assembly i ntermediate. (PubMed id 15590835)1, 3 Bernstein K.A....Baserga S.J. (2004)
    3. T lymphocyte activation gene identification by coregulated expression on DNA microarrays. (PubMed id 15177553)1, 2 Mao M.... Linsley P.S. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Distribution of WDR36 DNA sequence variants in patients with primary open-angle glaucoma. (PubMed id 16723468)1, 9 Hauser M.A....Wiggs J.L. (2006)
    6. Different WDR36 mutation pattern in Chinese patients with primary open-angle glaucoma. (PubMed id 19347049)1, 9 Fan B.J....Pang C.P. (2009)
    7. The role of the WDR36 gene on chromosome 5q22.1 in a large family with primary open-angle glaucoma mapped to this region. (PubMed id 16966629)1, 9 Kramer P.L....Wirtz M.K. (2006)
    8. [Genetic variants of CYP1B1 and WDR36 in the patients with primary congenital glaucoma and primary open angle glaucoma from Saint-Pe tersburg] (PubMed id 20198978)1, 9 Motushchuk A.E....Vasil'ev V.B. (2009)
    9. Multiple gene polymorphisms analysis revealed a different profile of genetic polymorphisms of primary open-angle glaucoma in northern Chinese. (PubMed id 19145250)1, 9 Jia L.Y....Wang N.L. (2009)
    10. Association between primary open-angle glaucoma and WDR36 DNA sequence variants in Japanese. (PubMed id 17960130)1, 9 Miyazawa A....Nishida K. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 134430 HGNC: 30696 AceView: WDR36 Ensembl:ENSG00000134987 euGenes: HUgn134430
    ECgene: WDR36 Kegg: 134430 H-InvDB: WDR36

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for WDR36 Pharmacogenomics, SNPs, Pathways
    GeneReviewshttp://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/WDR36

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for WDR36 gene:
    Search GeneIP for patents involving WDR36

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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