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WDR33 Gene

protein-coding   GIFtS: 54
GCID: GC02M128458

WD Repeat Domain 33

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
WD Repeat Domain 331 2
WDC1462 3
WD Repeat-Containing Protein 332 3
WD Repeat-Containing Protein WDC1462 3
NET142
Pre-MRNA 3' End Processing Protein WDR332

External Ids:    HGNC: 256511   Entrez Gene: 553392   Ensembl: ENSG000001367097   UniProtKB: Q9C0J83   

Export aliases for WDR33 gene to outside databases

Previous GC identifers: GC02M128557 GC02M128179 GC02M120768


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for WDR33 Gene:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of
approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation
of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular
processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is
highly expressed in testis and the protein is localized to the nucleus. This gene may play important roles in the
mechanisms of cytodifferentiation and/or DNA recombination. Multiple alternatively spliced transcript variants
encoding distinct isoforms have been found for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for WDR33 Gene:
WDR33 (WD repeat domain 33) is a protein-coding gene.

UniProtKB/Swiss-Prot: WDR33_HUMAN, Q9C0J8
Function: Essential for both cleavage and polyadenylation of pre-mRNA 3' ends

Gene Wiki entry for WDR33 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NT_005403.18  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the WDR33 gene promoter:
         E2F-4   E2F-3a   E2F-5   FOXF2   E2F-2   AREB6   E2F   E2F-1   POU2F1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidWDR33 promoter sequence
   Search Chromatin IP Primers for WDR33

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat WDR33


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q14.3   Ensembl cytogenetic band:  2q14.3   HGNC cytogenetic band: 2q21.1

WDR33 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WDR33 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M128458:  view genomic region     (about GC identifiers)

Start:
128,458,596 bp from pter      End:
128,568,761 bp from pter
Size:
110,166 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: WDR33_HUMAN, Q9C0J8 (See protein sequence)
Recommended Name: pre-mRNA 3' end processing protein WDR33  
Size: 1336 amino acids; 145891 Da
Subunit: Component of the cleavage and polyadenylation specificity factor (CPSF) module of the pre-mRNA 3'-end
processing complex. Interacts with CPSF3/CPSF73
Secondary accessions: Q05DP8 Q53FG9 Q587J1 Q69YF7 Q6NUQ0 Q9NUL1
Alternative splicing: 3 isoforms:  Q9C0J8-1   Q9C0J8-2   Q9C0J8-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for WDR33: NX_Q9C0J8

Explore proteomics data for WDR33 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys28, Lys46, Lys55, Lys65, Lys109, Lys119, Lys216
  • Modification sites at PhosphoSitePlus

  • See WDR33 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001006623.1  NP_001006624.1  NP_060853.3  

    ENSEMBL proteins: 
     ENSP00000325377   ENSP00000397547   ENSP00000376730   ENSP00000387186   ENSP00000386861  

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    Cloud-Clone Corp. Proteins for WDR33

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    WDR: WD repeat domain containing

    4 InterPro protein domains:
     IPR001680 WD40_repeat
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom
     IPR008160 Collagen

    Graphical View of Domain Structure for InterPro Entry Q9C0J8

    ProtoNet protein and cluster: Q9C0J8

    1 Blocks protein domain: IPB008160 Collagen triple helix repeat

    UniProtKB/Swiss-Prot: WDR33_HUMAN, Q9C0J8
    Similarity: Contains 1 collagen-like domain
    Similarity: Contains 7 WD repeats


    Find genes that share domains with WDR33           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: WDR33_HUMAN, Q9C0J8
    Function: Essential for both cleavage and polyadenylation of pre-mRNA 3' ends

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with WDR33           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for WDR33:
     Abundance of large cells with   Increased gamma-H2AX phosphory  Increased influenza A virus in 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for WDR33

    miRNA
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    miRTarBase miRNAs that target WDR33:
    hsa-mir-186-5p (MIRT021125), hsa-mir-19b-3p (MIRT031149), hsa-mir-615-3p (MIRT040378), hsa-let-7b-5p (MIRT032334), hsa-mir-1914-3p (MIRT035775), hsa-mir-93-5p (MIRT028001), hsa-mir-106b-5p (MIRT044276), hsa-mir-130b-3p (MIRT020148), hsa-mir-877-3p (MIRT036873), hsa-mir-1 (MIRT023762), hsa-mir-98-5p (MIRT027636)

    Block miRNA regulation of human, mouse, rat WDR33 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate WDR33 (see all 49):
    hsa-miR-485-3p hsa-let-7a-2* hsa-miR-624* hsa-miR-218 hsa-miR-1273d hsa-miR-1184 hsa-miR-4330 hsa-miR-23a
    SwitchGear 3'UTR luciferase reporter plasmidWDR33 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    WDR33_HUMAN, Q9C0J8: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    extracellular3
    cytosol2
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005581collagen IEA--
    GO:0005634nucleus IDA11162572

    Find genes that share ontologies with WDR33           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for WDR33 About    
    See pathways by source

    SuperPathContained pathways About
    1mRNA surveillance pathway
    mRNA surveillance pathway


    Find genes that share SuperPaths with WDR33           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for WDR33):
        mRNA surveillance pathway

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for WDR33
    Interactions:

        Search GeneGlobe Interaction Network for WDR33

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for WDR33 (Q9C0J82, 3 ENSP000003253774) via UniProtKB, MINT, STRING, and/or I2D (see all 822)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SUMO1P631652, 3, ENSP000003760764MINT-7947479 I2D: score=2 STRING: ENSP00000376076
    SMARCAD1Q9H4L72, ENSP000003519474MINT-7945693 MINT-7947479 STRING: ENSP00000351947
    BUB1BO605662, ENSP000002875984MINT-7945693 MINT-7947479 STRING: ENSP00000287598
    CDC5LQ994592, ENSP000003605324MINT-7945693 MINT-7947479 STRING: ENSP00000360532
    BUB1O436832, ENSP000003025304MINT-7945693 MINT-7947479 STRING: ENSP00000302530
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006301postreplication repair NAS11162572
    GO:0006397mRNA processing IEA--
    GO:0007283spermatogenesis NAS11162572

    Find genes that share ontologies with WDR33           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for WDR33



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for WDR33 gene (3 alternative transcripts): 
    NM_001006622.2  NM_001006623.2  NM_018383.4  

    Unigene Cluster for WDR33:

    WD repeat domain 33
    Hs.554831  [show with all ESTs]
    Unigene Representative Sequence: NM_018383
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000322313(uc002tpg.2) ENST00000436787 ENST00000393006(uc002tph.2)
    ENST00000409658(uc002tpi.2) ENST00000408998
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate WDR33 (see all 49):
    hsa-miR-485-3p hsa-let-7a-2* hsa-miR-624* hsa-miR-218 hsa-miR-1273d hsa-miR-1184 hsa-miR-4330 hsa-miR-23a
    SwitchGear 3'UTR luciferase reporter plasmidWDR33 3' UTR sequence
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      QuantiFast Probe-based Assays in human, mouse, rat WDR33

    Additional mRNA sequence: 

    AB044749.1 AK002156.1 AK098003.1 AK123510.1 AK223319.1 AL834365.1 BC005401.1 BC010283.1 
    BC013990.2 BC068484.1 BC108671.1 

    19 DOTS entries:

    DT.85105571  DT.101981406  DT.99988925  DT.210433  DT.95193952  DT.410657  DT.114076  DT.95277296 
    DT.100777349  DT.100751287  DT.100777350  DT.216281  DT.92436263  DT.95287644  DT.120966393  DT.120966449 
    DT.121488446  DT.40121162  DT.91988481 

    Selected AceView cDNA sequences (see all 298):

    F10034 BQ640405 AL834365 BM751741 BX377265 CR591938 BM751937 Z41772 
    AW243049 AW167162 BQ233548 AI418601 AI039494 AW407659 AA809425 F12417 
    BM994732 BC013990 BF515130 CB069962 AA235688 AA908953 AA062884 AI288678 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for WDR33 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15a · 15b ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^
    SP1:                    -     -                                         -           -     -     -                             -                                 
    SP2:                    -     -                                         -           -     -                                                                     
    SP3:                                                                                                                                                            
    SP4:                    -     -                                                                                                                                 
    SP5:                    -                                                                                                                                       

    ExUns: 21a · 21b ^ 22a · 22b ^ 23a · 23b ^ 24 ^ 25 ^ 26 ^ 27
    SP1:                                                            
    SP2:                                                            
    SP3:                    -     -                                 
    SP4:                                                            
    SP5:                                                            


    ECgene alternative splicing isoforms for WDR33

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    WDR33 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGCTCTGTCA
    WDR33 Expression
    About this image

    WDR33 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    WDR33 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.554831

    UniProtKB/Swiss-Prot: WDR33_HUMAN, Q9C0J8
    Tissue specificity: Most highly expressed in testis

        Custom PCR Arrays for WDR33
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for WDR33 gene from Selected species (see all 23)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Wdr331 , 5 WD repeat domain 331, 5 90.26(n)1
    96.43(a)1
      18 (17.85 cM)5
    743201  NM_028866.31  NP_083142.21 
     318040575 
    chicken
    (Gallus gallus)
    Aves WDR331 WD repeat domain 33 80.77(n)
    89.64(a)
      424753  XM_004936955.1  XP_004937012.1 
    lizard
    (Anolis carolinensis)
    Reptilia WDR336
    WD repeat domain 33
    87(a)
    1 ↔ 1
    3(36266342-36326082)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.151122 Xenopus laevis, Similar to hypothetical protein FLJ11294, more 75.39(n)    BC044081.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.123302 Transcribed sequence with weak similarity to protein more 79.2(n)    BI890241.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG11096
    --
    50(a)
    1 ↔ 1
    3R(1486359-1491168)
    worm
    (Caenorhabditis elegans)
    Secernentea pfs-26
    Protein PFS-2 (pfs-2) mRNA, complete cds
    43(a)
    1 ↔ 1
    II(14358392-14361683) WBGene00011051
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PFS2(YNL317W)4
    PFS21
    Integral subunit of the pre-mRNA cleavage and polyadenylation more4
    PFS21
    49.95(n)1
    41.6(a)1
      14(40619-42016)4
    8553991, 4  NP_014082.11, 4 
    rice
    (Oryza sativa)
    Liliopsida Os.160052 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 70.93(n)    AK111493.1 


    ENSEMBL Gene Tree for WDR33 (if available)
    TreeFam Gene Tree for WDR33 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for WDR33 gene
    3 SIMAP similar genes for WDR33 using alignment to 3 protein entries:     WDR33_HUMAN (see all proteins):
    CORO1C    PF20    POC1B

    Find genes that share paralogs with WDR33           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for WDR33 (see all 2310)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1860513211,2
    --128462015(+) TGATAC/TGGGTT 1 -- ut310--------
    rs1487095681,2
    C--128462108(+) AGAAAC/TACCCA 1 -- ut310--------
    rs790032091,2
    C,F--128462134(+) TTGAGC/TCTCCT 1 -- ut311Minor allele frequency- T:0.05EA 120
    rs1908187161,2
    --128462155(+) TTATGC/GTGGAG 1 -- ut310--------
    rs1437105821,2
    C--128462161(+) TGGAGC/TGCTGA 1 -- ut310--------
    rs1468261651,2
    C--128462403(+) AGATCG/TGCAAT 1 -- ut310--------
    rs1812435571,2
    --128462478(+) ACAAAC/GTGGTG 1 -- ut310--------
    rs1405890411,2
    --128462512(+) CACACA/TCAAAA 1 -- ut310--------
    rs744662421,2
    C,F--128462513(+) ACACAC/AAAAAA 1 -- ut316Minor allele frequency- A:0.08WA CSA NA EA 364
    rs134013321,2
    C,A--128462538(+) gtggcA/Gtatgc 1 -- ut31 ese30--------

    HapMap Linkage Disequilibrium report for WDR33 (128458596 - 128568761 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for WDR33:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2672967CNV Deletion23128226
    esv2659176CNV Deletion23128226
    nsv875030CNV Loss21882294
    nsv470482CNV Loss18288195
    nsv875033CNV Loss21882294
    dgv4301n71CNV Loss21882294
    esv26495CNV Loss19812545
    nsv875015CNV Loss21882294
    dgv4299n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing WDR33
    DNA2.0 Custom Variant and Variant Library Synthesis for WDR33

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for WDR33 gene, integrated from 10 sources (see all 40):
    (articles sorted by number of sources associating them with WDR33)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel WD40 repeat protein, WDC146, highly expressed during spermatogenesis in a stage-specific manner. (PubMed id 11162572)1, 2, 3 Ito S....Shimizu K. (Biochem. Biophys. Res. Commun. 2001)
    2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Genetics of coronary artery calcification among African Americans, a meta-analysis. (PubMed id 23870195)1 Wojczynski M.K....Reilly M.P. (BMC Med. Genet. 2013)
    5. Gene network analysis in a pediatric cohort identifies novel lung function genes. (PubMed id 24023788)1 Ong B.A....Hakonarson H. (PLoS ONE 2013)
    6. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
    7. The functional interactome landscape of the human histone deacetylase family. (PubMed id 23752268)1 Joshi P....Cristea I.M. (Mol. Syst. Biol. 2013)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    9. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    10. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55339 HGNC: 25651 AceView: WDR33 Ensembl:ENSG00000136709 euGenes: HUgn55339
    ECgene: WDR33 Kegg: 55339 H-InvDB: WDR33

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for WDR33 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for WDR33 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for WDR33 gene:
    Search GeneIP for patents involving WDR33

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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