Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

WDR33 Gene

protein-coding   GIFtS: 51
GCID: GC02M128458

WD repeat domain 33

 Explore 1 disease affiliated with
WDR33 via our new
 Human Malady Compendium 
Biological research products
for WDR33
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
WD Repeat Domain 331 2     WD Repeat-Containing Protein WDC1462 3
WDC1461 2 3     FLJ112941
NET141 2     Pre-MRNA 3' End Processing Protein WDR332
WD Repeat-Containing Protein 332 3     

External Ids:    HGNC: 256511   Entrez Gene: 553392   Ensembl: ENSG000001367097   UniProtKB: Q9C0J83   

Export aliases for WDR33 gene to outside databases

Previous GC identifers: GC02M128557 GC02M128179 GC02M120768


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for WDR33:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately
40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or
multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle
progression, signal transduction, apoptosis, and gene regulation. This gene is highly expressed in testis and the
protein is localized to the nucleus. This gene may play important roles in the mechanisms of cytodifferentiation
and/or DNA recombination. Multiple alternatively spliced transcript variants encoding distinct isoforms have been
found for this gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: WDR33_HUMAN, Q9C0J8
Function: Essential for both cleavage and polyadenylation of pre-mRNA 3' ends

Gene Wiki entry for WDR33


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_022135.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the WDR33 gene promoter:
         E2F-4   E2F-3a   E2F-5   FOXF2   E2F-2   AREB6   E2F   E2F-1   POU2F1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidWDR33 promoter sequence
   Search SABiosciences Chromatin IP Primers for WDR33

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WDR33


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q14.3   Ensembl cytogenetic band:  2q14.3   HGNC cytogenetic band: 2q21.1

WDR33 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WDR33 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M128458:  view genomic region     (about GC identifiers)

Start:
128,458,596 bp from pter      End:
128,568,761 bp from pter
Size:
110,166 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: WDR33_HUMAN, Q9C0J8 (See protein sequence)
Recommended Name: pre-mRNA 3' end processing protein WDR33  
Size: 1336 amino acids; 145891 Da
Subunit: Component of the cleavage and polyadenylation specificity factor (CPSF) module of the pre-mRNA 3' end
processing complex. Interacts with CPSF3/CPSF73
Subcellular location: Nucleus
Secondary accessions: Q05DP8 Q53FG9 Q587J1 Q69YF7 Q6NUQ0 Q9NUL1
Alternative splicing: 3 isoforms:  Q9C0J8-1   Q9C0J8-2   Q9C0J8-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for WDR33: NX_Q9C0J8

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9C0J8

  • WDR33 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001006623.1  NP_001006624.1  NP_060853.3  

    ENSEMBL proteins: 
     ENSP00000325377   ENSP00000397547   ENSP00000376730   ENSP00000387186   ENSP00000386861  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom Protein Services for WDR33 
    GenScript Custom Purified and Recombinant Proteins Services for WDR33
    Novus Biologicals WDR33 Protein
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for WDR33

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005581collagen IEA--
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--


    WDR33 for ontologies           About GeneDecksing



    WDR33 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for WDR33 
    GenScript Custom Superior Antibodies Services for WDR33
    Novus Biologicals WDR33 Antibodies
    Search for Antibodies for WDR33 at Abcam  
    Uscn Antibodies for WDR33
    Search ThermoFisher Antibodies for WDR33

    Assay Products for WDR33: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for WDR33
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for WDR33


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    WDR33 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR001680 WD40_repeat
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom
     IPR008160 Collagen

    Graphical View of Domain Structure for InterPro Entry Q9C0J8

    ProtoNet protein and cluster: Q9C0J8

    1 Blocks protein family: IPB008160 Collagen triple helix repeat

    UniProtKB/Swiss-Prot: WDR33_HUMAN, Q9C0J8
    Similarity: Contains 1 collagen-like domain
    Similarity: Contains 7 WD repeats


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: WDR33_HUMAN, Q9C0J8
    Function: Essential for both cleavage and polyadenylation of pre-mRNA 3' ends

    miRNA
    Products:
        
    OriGene 3'-UTR Clone (see all 2): WDR33
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat WDR33
    8/49 QIAGEN miScript miRNA Assays for microRNAs that regulate WDR33 (see all 49):
    hsa-miR-485-3p hsa-let-7a-2* hsa-miR-624* hsa-miR-218 hsa-miR-1273d hsa-miR-1184 hsa-miR-4330 hsa-miR-23a
    SwitchGear 3'UTR luciferase reporter plasmidWDR33 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for WDR33 (see all 7)
    OriGene shRNA RFP: WDR33
    OriGene siRNA: WDR33
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat WDR33

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for WDR33

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WDR33 (see all 8)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WDR33 (see all 4)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 3): WDR33 (NM_018383)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for WDR33
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR33 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for WDR33
    Search LifeMap BioReagents cell lines for WDR33

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR33

    3 GenomeRNAi human phenotypes for WDR33:
     Abundance of large cells with   Increased gamma-H2AX phosphory  Increased influenza A virus in 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for WDR33

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    5/755 Interacting proteins for WDR33 (Q9C0J82, 3 ENSP000003253774) via UniProtKB, MINT, STRING, and/or I2D (see all 755)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SUMO1P631652, 3, ENSP000003760764MINT-7947479 I2D: score=2 STRING: ENSP00000376076
    SMARCAD1Q9H4L72, ENSP000003519474MINT-7945693 MINT-7947479 STRING: ENSP00000351947
    CDC5LQ994592, ENSP000003605324MINT-7945693 MINT-7947479 STRING: ENSP00000360532
    CPSF2Q9P2I02, ENSP000002988754MINT-7945693 MINT-7947479 STRING: ENSP00000298875
    ELAVL1Q157172, ENSP000003852694MINT-7945693 MINT-7947479 STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006301postreplication repair NAS11162572
    GO:0006397mRNA processing IEA--
    GO:0007283spermatogenesis NAS11162572


    WDR33 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for WDR33
    Search CenterWatch for drugs/clinical trials and news about WDR33 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for WDR33 gene (3 alternative transcripts): 
    NM_001006622.2  NM_001006623.2  NM_018383.4  

    Unigene Cluster for WDR33:

    WD repeat domain 33
    Hs.554831  [show with all ESTs]
    Unigene Representative Sequence: NM_018383
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000322313(uc002tpg.2) ENST00000436787 ENST00000393006(uc002tph.2)
    ENST00000409658(uc002tpi.2) ENST00000408998

    miRNA
    Products:
         
    OriGene 3'-UTR Clone (see all 2): WDR33
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat WDR33
    8/49 QIAGEN miScript miRNA Assays for microRNAs that regulate WDR33 (see all 49):
    hsa-miR-485-3p hsa-let-7a-2* hsa-miR-624* hsa-miR-218 hsa-miR-1273d hsa-miR-1184 hsa-miR-4330 hsa-miR-23a
    SwitchGear 3'UTR luciferase reporter plasmidWDR33 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for WDR33 (see all 7)
    OriGene shRNA RFP: WDR33
    OriGene siRNA: WDR33
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat WDR33
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WDR33 (see all 8)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WDR33 (see all 4)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 3): WDR33 (NM_018383)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for WDR33
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR33 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for WDR33
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat WDR33
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDR33
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR33

    Additional cDNA sequence: 

    AB044749.1 AK002156.1 AK098003.1 AK123510.1 AK223319.1 AL834365.1 BC005401.1 BC010283.1 
    BC013990.2 BC068484.1 BC108671.1 

    19 DOTS entries:

    DT.85105571  DT.101981406  DT.99988925  DT.210433  DT.95193952  DT.410657  DT.114076  DT.95277296 
    DT.100777349  DT.100751287  DT.100777350  DT.216281  DT.92436263  DT.95287644  DT.120966393  DT.120966449 
    DT.121488446  DT.40121162  DT.91988481 

    24/298 AceView cDNA sequences (see all 298):

    BF515130 BG644317 BQ011321 AA582649 BU846163 AI480300 BM994732 AA809425 
    AA235688 BU633446 AI288678 AW968222 BC068484 BE747336 AI678924 CB069962 
    BC013990 BU538276 BQ896760 BQ277834 BF593522 F12417 BM680528 AU138991 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for WDR33 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15a · 15b ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^
    SP1:                    -     -                                         -           -     -     -                             -                                 
    SP2:                    -     -                                         -           -     -                                                                     
    SP3:                                                                                                                                                            
    SP4:                    -     -                                                                                                                                 
    SP5:                    -                                                                                                                                       

    ExUns: 21a · 21b ^ 22a · 22b ^ 23a · 23b ^ 24 ^ 25 ^ 26 ^ 27
    SP1:                                                            
    SP2:                                                            
    SP3:                    -     -                                 
    SP4:                                                            
    SP5:                                                            


    ECgene alternative splicing isoforms for WDR33

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    WDR33 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGCTCTGTCA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See WDR33 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for WDR33

    SOURCE GeneReport for Unigene cluster: Hs.554831

    UniProtKB/Swiss-Prot: WDR33_HUMAN, Q9C0J8
    Tissue specificity: Most highly expressed in testis

        SABiosciences Custom PCR Arrays for WDR33
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for WDR33
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat WDR33
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDR33
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR33
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR33

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for WDR33 gene from 9/33 species (see all 33)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves WDR331 WD repeat domain 33 81.33(n)
    90.51(a)
      424753  XM_422575.3  XP_422575.2 
    lizard
    (Anolis carolinensis)
    Reptilia WDR336
    COPA6
    --
    84(a)
    11(a)
    1 ↔ 1
    possible ortholog
    3(36266342-36315008)
    AAWZ02039946(278-5338)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.151122 Xenopus laevis, Similar to hypothetical protein FLJ11294, more 75.39(n)    BC044081.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.123302 Transcribed sequence with weak similarity to protein more 79.2(n)    BI890241.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG11096
    --
    43(a)
    1 ↔ 1
    3R(1486359-1491168)
    worm
    (Caenorhabditis elegans)
    Secernentea pfs-21 Protein PFS-2 52.48(n)
    47.1(a)
      175092  NM_064584.2  NP_496985.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PFS2(YNL317W)4
    PFS21
    Integral subunit of the pre-mRNA cleavage and polyadenylation more4
    Pfs2p1
    48.95(n)1
    40.57(a)1
      14(40619-42016)4
    8553991, 4  NP_014082.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons FY1 Flowering time control protein FY 54.27(n)
    47.78(a)
      831191  NM_121351.4  NP_196852.3 
    rice
    (Oryza sativa)
    Liliopsida Os.160052 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 70.93(n)    AK111493.1 


    ENSEMBL Gene Tree for WDR33 (if available)
    TreeFam Gene Tree for WDR33 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for WDR33 gene
    PRH12  PRB42  PRB12  PRH22  PRB22  
    3 SIMAP similar genes for WDR33 using alignment to 3 protein entries:     WDR33_HUMAN (see all proteins):
    CORO1C    PF20    POC1B

    WDR33 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1931 NCBI SNPs in WDR33 are shown (see all 1931    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs133976701,2
    C,A,--128461472(+) ggatcA/Gcttga 2 -- int1 ds50010--------
    rs1845517461,2
    --128461519(+) AAACCC/TCATCG 2 -- int1 ds50010--------
    rs75847831,2
    C,F,A,H,--128461524(+) CCATCG/TCCACA 2 -- int1 ds500112Minor allele frequency- T:0.32NS EA NA WA CSA 741
    rs1892805541,2
    --128461534(+) AGAAAA/GTCTTC 2 -- int1 ds50010--------
    rs75754781,2
    C,F,A,H,--128461556(+) CAGATA/GTGGTG 2 -- ds5001 int120Minor allele frequency- G:0.35NS EA NA WA CSA 2337
    rs134119171,2
    C,--128461627(+) caggaA/Ggttga 2 -- int1 ds50010--------
    rs134119241,2
    C,--128461637(+) aggctA/Gcagtg 2 -- ds5001 int10--------
    rs133873801,2
    C,F,A,H,--128461734(+) ATCTAC/GTTTTT 2 -- ds5001 int15Minor allele frequency- G:0.01NS EA WA 528
    rs1819491031,2
    --128461875(+) TCCAGC/TAGAGC 2 -- ut31 int10--------
    rs1860513211,2
    --128462015(+) TGATAC/TGGGTT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for WDR33 (128458596 - 128568761 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for WDR33
         3 CNVs: 68157 30103 89945

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing WDR33
    DNA2.0 Custom Variant and Variant Library Synthesis for WDR33

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    WDR33 for disorders           About GeneDecksing

    1 disease for WDR33:    About MalaCards
    malaria


    Export disorders for WDR33 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for WDR33 gene, integrated from 9 sources (see all 34):
    (articles sorted by number of sources associating them with WDR33)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel WD40 repeat protein, WDC146, highly expressed during spermatogenesis in a stage-specific manner. (PubMed id 11162572)1, 2, 3 Ito S....Shimizu K. (2001)
    2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    5. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
    6. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    7. DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation. (PubMed id 22446626)1 Close P.... Svejstrup J.Q. (2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55339 HGNC: 25651 AceView: WDR33 Ensembl:ENSG00000136709 euGenes: HUgn55339
    ECgene: WDR33 H-InvDB: WDR33

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for WDR33 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for WDR33 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for WDR33 gene:
    Search GeneIP for patents involving WDR33

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for WDR33  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for WDR33   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for WDR33  
     Browse OriGene Protein Over-expression Lysates   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for WDR33   OriGene 3'-UTR Clone for WDR33  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WDR33   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WDR33  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for WDR33   OriGene Custom Protein Services for WDR33  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat WDR33
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing WDR33
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WDR33
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat WDR33
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR33
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDR33
     GenScript Custom Purified and Recombinant Proteins Services for WDR33 GenScript cDNA clones with any tag delivered in your preferred vector for WDR33
     GenScript Custom Assay Services for WDR33 GenScript Custom Superior Antibodies Services for WDR33
     GenScript Custom overexpressing Cell Line Services for WDR33 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in WDR33 promoter
     Search Chromatin IP Primers for WDR33
     RT2 qPCR Primer Assay in human, mouse, rat WDR33
     Search GNC Networks for WDR33
     SABiosciences Custom PCR Arrays for WDR33
     Search Tocris compounds for WDR33
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     WDR33 antibodies
     WDR33 proteins
     Search for Antibodies for WDR33 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for WDR33
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     WDR33 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for WDR33
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR33
     SwitchGear 3'UTR luciferase reporter plasmids for WDR33
     SwitchGear Promoter luciferase reporter plasmids for WDR33
     Search ThermoFisher Antibodies for WDR33
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR33
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      WDR33 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4