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Aliases for WDR31 Gene

Aliases for WDR31 Gene

  • WD Repeat Domain 31 2 3
  • Similar To Spermatid WD-Repeat Protein 2

External Ids for WDR31 Gene

Previous GeneCards Identifiers for WDR31 Gene

  • GC09M111451
  • GC09M113155
  • GC09M115115
  • GC09M116077
  • GC09M085685

Summaries for WDR31 Gene

Entrez Gene Summary for WDR31 Gene

  • This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]

GeneCards Summary for WDR31 Gene

WDR31 (WD Repeat Domain 31) is a Protein Coding gene. An important paralog of this gene is GNB2L1.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR31 Gene

Genomics for WDR31 Gene

Regulatory Elements for WDR31 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for WDR31 Gene

113,313,222 bp from pter
113,340,340 bp from pter
27,119 bases
Minus strand

Genomic View for WDR31 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for WDR31 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WDR31 Gene

Proteins for WDR31 Gene

  • Protein details for WDR31 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    WD repeat-containing protein 31
    Protein Accession:
    Secondary Accessions:
    • Q5W0T9
    • Q96EG8

    Protein attributes for WDR31 Gene

    367 amino acids
    Molecular mass:
    40840 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for WDR31 Gene


neXtProt entry for WDR31 Gene

Proteomics data for WDR31 Gene at MOPED

Post-translational modifications for WDR31 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for WDR31 Gene

Antibody Products

No data available for DME Specific Peptides for WDR31 Gene

Domains for WDR31 Gene

Gene Families for WDR31 Gene

Suggested Antigen Peptide Sequences for WDR31 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 7 WD repeats.
  • Contains 7 WD repeats.
genes like me logo Genes that share domains with WDR31: view

Function for WDR31 Gene

Gene Ontology (GO) - Molecular Function for WDR31 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with WDR31: view

Phenotypes for WDR31 Gene

GenomeRNAi human phenotypes for WDR31:
genes like me logo Genes that share phenotypes with WDR31: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for WDR31 Gene

Localization for WDR31 Gene

Subcellular locations from

Jensen Localization Image for WDR31 Gene COMPARTMENTS Subcellular localization image for WDR31 gene
Compartment Confidence
cytosol 3
nucleus 3
mitochondrion 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for WDR31 Gene

Pathways for WDR31 Gene

SuperPathways for WDR31 Gene

No Data Available

Interacting Proteins for WDR31 Gene

Gene Ontology (GO) - Biological Process for WDR31 Gene


No data available for Pathways by source for WDR31 Gene

Transcripts for WDR31 Gene

Unigene Clusters for WDR31 Gene

WD repeat domain 31:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for WDR31

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for WDR31 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b
SP1: -
SP2: -
SP3: -
SP4: - -

Relevant External Links for WDR31 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for WDR31 Gene

mRNA expression in normal human tissues for WDR31 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for WDR31 Gene

This gene is overexpressed in Heart - Left Ventricle (4.4).

Protein differential expression in normal tissues for WDR31 Gene

This gene is overexpressed in Pancreatic juice (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for WDR31 Gene

SOURCE GeneReport for Unigene cluster for WDR31 Gene Hs.133331

genes like me logo Genes that share expressions with WDR31: view

Expression partners for WDR31 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for WDR31 Gene

Orthologs for WDR31 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for WDR31 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia WDR31 35
  • 86.98 (n)
  • 86.61 (a)
WDR31 36
  • 86 (a)
(Canis familiaris)
Mammalia WDR31 35
  • 89.22 (n)
  • 88.49 (a)
-- 36
  • 79 (a)
-- 36
  • 85 (a)
(Mus musculus)
Mammalia Wdr31 35
  • 85.1 (n)
  • 83.11 (a)
Wdr31 16
Wdr31 36
  • 83 (a)
(Pan troglodytes)
Mammalia WDR31 35
  • 99.64 (n)
  • 99.73 (a)
WDR31 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Wdr31 35
  • 85.2 (n)
  • 83.11 (a)
(Monodelphis domestica)
Mammalia WDR31 36
  • 70 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 55 (a)
-- 36
  • 76 (a)
(Gallus gallus)
Aves WDR31 35
  • 66.08 (n)
  • 63.64 (a)
WDR31 36
  • 62 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.17269 35
(Danio rerio)
Actinopterygii si:ch73-266o15.4 35
  • 59.84 (n)
  • 53.8 (a)
WDR31 36
  • 54 (a)
(Caenorhabditis elegans)
Secernentea T05A8.5 36
  • 24 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ASC1 36
  • 20 (a)
Species with no ortholog for WDR31:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for WDR31 Gene

Gene Tree for WDR31 (if available)
Gene Tree for WDR31 (if available)

Paralogs for WDR31 Gene

Paralogs for WDR31 Gene

(4) SIMAP similar genes for WDR31 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with WDR31: view

Variants for WDR31 Gene

Sequence variations from dbSNP and Humsavar for WDR31 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs730296 -- 113,322,242(+) aagac(A/C)cagac intron-variant
rs932708 -- 113,337,986(+) GAGCT(A/G)AAACT intron-variant
rs1323466 -- 113,320,968(-) AATAA(A/G)AAGCA intron-variant
rs1543535 -- 113,336,655(+) ATTTT(G/T)CTCAT intron-variant
rs2296075 -- 113,317,151(-) ACCCC(A/G)ACACT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for WDR31 Gene

Variant ID Type Subtype PubMed ID
nsv893744 CNV Gain 21882294
esv6353 CNV Gain 19470904
nsv521449 CNV Loss 19592680

Relevant External Links for WDR31 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WDR31 Gene

Disorders for WDR31 Gene

Relevant External Links for WDR31

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for WDR31 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for WDR31 Gene

Publications for WDR31 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study. (PMID: 17975119) Shiffman D. … Psaty B.M. (Arterioscler. Thromb. Vasc. Biol. 2008) 3 48
  4. Gene variants associated with ischemic stroke: the cardiovascular health study. (PMID: 19023099) Luke M.M. … Psaty B.M. (Stroke 2009) 3 48
  5. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4

Products for WDR31 Gene

Sources for WDR31 Gene

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