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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

WDR3 Gene

protein-coding   GIFtS: 58
GCID: GC01P118472

WD Repeat Domain 3

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
WD Repeat Domain 31 2
DIP22
UTP122
DJ776P7.2 (WD Repeat Domain 3)2
WD Repeat-Containing Protein 32

External Ids:    HGNC: 127551   Entrez Gene: 108852   Ensembl: ENSG000000651837   OMIM: 6047375   UniProtKB: Q9UNX43   

Export aliases for WDR3 gene to outside databases

Previous GC identifers: GC01P118934 GC01P117313 GC01P117622 GC01P117822 GC01P117818 GC01P118184 GC01P116328


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for WDR3 Gene:
This gene encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid
domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Proteins
belonging to the WD repeat family are involved in a variety of cellular processes, including cell cycle
progression, signal transduction, apoptosis, and gene regulation. (provided by RefSeq, Jul 2008)

GeneCards Summary for WDR3 Gene: 
WDR3 (WD repeat domain 3) is a protein-coding gene. Diseases associated with WDR3 include thyroid cancer, and thyroiditis.

Gene Wiki entry for WDR3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the WDR3 gene promoter:
         AP-1   FOXD3   LCR-F1   HNF-1A   Roaz   GATA-1   HEN1   Pax-3   HNF-1   Chx10   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidWDR3 promoter sequence
   Search SABiosciences Chromatin IP Primers for WDR3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WDR3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p12   Ensembl cytogenetic band:  1p12   HGNC cytogenetic band: 1p12

WDR3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WDR3 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P118472:  view genomic region     (about GC identifiers)

Start:
118,472,343 bp from pter      End:
118,503,049 bp from pter
Size:
30,707 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: WDR3_HUMAN, Q9UNX4 (See protein sequence)
Recommended Name: WD repeat-containing protein 3  
Size: 943 amino acids; 106099 Da
Subcellular location: Nucleus, nucleolus

Explore the universe of human proteins at neXtProt for WDR3: NX_Q9UNX4

Explore proteomics data for WDR3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9UNX4

  • WDR3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    WDR3 Protein Expression
    REFSEQ proteins: NP_006775.1  
    ENSEMBL proteins: 
     ENSP00000308179   ENSP00000358449  

    Human Recombinant Protein Products for WDR3: 
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    Cloud-Clone Corp. Proteins for WDR3 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--
    GO:0031965nuclear membrane IDA--

    WDR3 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    WDR: WD repeat domain containing

    5/6 InterPro protein domains (see all 6):
     IPR019775 WD40_repeat_CS
     IPR001680 WD40_repeat
     IPR020472 G-protein_beta_WD-40_rep
     IPR007148 SSU_processome_Utp12
     IPR017986 WD40_repeat_dom

    Graphical View of Domain Structure for InterPro Entry Q9UNX4

    ProtoNet protein and cluster: Q9UNX4

    1 Blocks protein domain: IPB007148 Dip2/Utp12

    UniProtKB/Swiss-Prot: WDR3_HUMAN, Q9UNX4
    Similarity: Belongs to the WD repeat WDR3/UTP12 family
    Similarity: Contains 13 WD repeats


    WDR3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:
         Genatlas biochemistry entry for WDR3:
    WD repeat domain 3,expressed in hematopoietic cell lines and in non hematopoietic tissues,involved in cell cycle
    progression,apoptosis gene regulation

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    WDR3 for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for WDR3:
     Decreased viability of wild-ty  Nuclear pre-40S maturation def  Synthetic lethal with Ras  Synthetic lethal with c-Myc af 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Wdr3):
     mortality/aging 

    WDR3 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for WDR3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for WDR3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for WDR3 
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    miRNA
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    5 QIAGEN miScript miRNA Assays for microRNAs that regulate WDR3:
    hsa-miR-203 hsa-miR-320a hsa-miR-320b hsa-miR-320d hsa-let-7f-2*
    SwitchGear 3'UTR luciferase reporter plasmidWDR3 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for WDR3 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Ribosome biogenesis in eukaryotes
    Ribosome biogenesis in eukaryotes

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for WDR3):
        Ribosome biogenesis in eukaryotes


    WDR3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for WDR3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/96 Interacting proteins for WDR3 (Q9UNX42, 3 ENSP000003081794) via UniProtKB, MINT, STRING, and/or I2D (see all 96)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for WDR3

    Search CenterWatch for drugs/clinical trials and news about WDR3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for WDR3 gene: 
    NM_006784.2  

    Unigene Cluster for WDR3:

    WD repeat domain 3
    Hs.310809  [show with all ESTs]
    Unigene Representative Sequence: NM_006784
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000487202 ENST00000349139(uc001ehi.2 uc010oxe.1) ENST00000471680
    ENST00000369441(uc001ehh.2)
    miRNA
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    5 QIAGEN miScript miRNA Assays for microRNAs that regulate WDR3:
    hsa-miR-203 hsa-miR-320a hsa-miR-320b hsa-miR-320d hsa-let-7f-2*
    SwitchGear 3'UTR luciferase reporter plasmidWDR3 3' UTR sequence
    Inhib. RNA
    Products:
         
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR3
    Sirion Biotech Customized lentivirus for stable overexpression of WDR3 
                         Customized lentivirus expression plasmids for stable overexpression of WDR3 
    Primer
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    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat WDR3
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDR3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR3

    Additional mRNA sequence: 

    AB209201.1 AF083217.1 AK022858.1 AK292438.1 BC058836.1 BC128385.1 BC128454.1 BC148244.1 

    11 DOTS entries:

    DT.95370125  DT.412006  DT.121463746  DT.100022302  DT.100748877  DT.319947  DT.302646  DT.40290469 
    DT.423063  DT.95271952  DT.206431 

    24/111 AceView cDNA sequences (see all 111):

    BF062207 BU167311 AA916500 BM469992 BI093749 CB244006 AU124711 BU685685 
    BU160827 BU608104 CR620639 AI922229 AU124009 BM543069 BE745523 H42014 
    AI492156 AK022858 AA514680 BG105708 AA423985 BE505015 H42013 BF445663 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for WDR3 (see all 9)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b · 13c ^ 14a · 14b ^ 15 ^ 16 ^ 17a · 17b ^ 18 ^
    SP1:                                                                                                                                                            
    SP2:              -     -     -           -                                                                                                                     
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32
    SP1:                                                                                    
    SP2:                                                                                    
    SP3:                                                                          -         
    SP4:                                                                                    
    SP5:                                                                                    


    ECgene alternative splicing isoforms for WDR3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    WDR3 expression in normal human tissues (normalized intensities)      WDR3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATCTTAGAG
    WDR3 Expression
    About this image


    WDR3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/16 selected tissues (see all 16) fully expand
     
     Epithelium
             vagina ; squamous epithelial cells   
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
     
     Colon (Gastrointestinal Tract)    fully expand to see all 2 entries
             rectum ; glandular cells   
     
     Testis (Reproductive System)    fully expand to see all 2 entries
             testis ; cells in seminiferus ducts   
     
     Placenta (Extraembryonic Tissues)    fully expand to see all 2 entries
             placenta ; decidual cells   

    See WDR3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for WDR3

    SOURCE GeneReport for Unigene cluster: Hs.310809

    UniProtKB/Swiss-Prot: WDR3_HUMAN, Q9UNX4
    Tissue specificity: Ubiquitous

        SABiosciences Custom PCR Arrays for WDR3
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for WDR3 gene from 10/25 species (see all 25)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Wdr31 , 5 WD repeat domain 31, 5 85.8(n)1
    91.18(a)1
      3 (43.46 cM)5
    2694701  NM_175552.41  NP_780761.11 
     1001381805 
    chicken
    (Gallus gallus)
    Aves WDR31 WD repeat domain 3 75.2(n)
    80.28(a)
      427952  NM_001031485.1  NP_001026656.1 
    lizard
    (Anolis carolinensis)
    Reptilia WDR36
    Uncharacterized protein
    75(a)
    1 ↔ 1
    GL343218.1(879296-910320)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.48342 Xenopus laevis transcribed sequence with moderate similarity more 74.82(n)    CD303393.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wdr32 WD repeat domain 3 75.68(n)   321058  BC057490.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG80641 , 3 CG80641 41(a)3
    50.67(n)1
    44.97(a)1
      91A13
    421961  NM_142448.31  NP_650705.11 
    worm
    (Caenorhabditis elegans)
    Secernentea F13H8.21 , 3 beta transducin Trp-Asp domains3
    Protein F13H8.21
    33(a)3
    48.9(n)1
    35.82(a)1
      II(6270322-6273677)3
    1740381  NM_062855.31  NP_495256.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes DIP2(YLR129W)4
    DIP21
    Nucleolar protein, specifically associated with the more4
    Dip2p1
    50.98(n)1
    41.61(a)1
      12(399657-402488)4
    8508201, 4  NP_013230.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G215401 transducin/WD40 domain-containing protein 49.56(n)
    41.69(a)
      821708  NM_113049.3  NP_188791.3 
    rice
    (Oryza sativa)
    Liliopsida Os.96222 Oryza sativa (japonica cultivar-group) isolate 29961 more 75.27(n)    AK101270.1 


    ENSEMBL Gene Tree for WDR3 (if available)
    TreeFam Gene Tree for WDR3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/494 SNPs in WDR3 are shown (see all 494)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1474250271,2
    --118474354(+) GAGTCC/TGGAGG 1 -- int10--------
    rs1381049501,2
    C--118474381(+) AAAGAA/GTTAAT 1 -- int10--------
    rs1874453541,2
    --118474464(+) TGGTTC/TCTGTG 1 -- int10--------
    rs170377541,2
    C,F,H--118474542(+) TTTTTG/TTGTTA 1 -- int118Minor allele frequency- T:0.08NA NS EA WA CSA 2119
    rs1129492001,2
    C--118474542(+) TTTTTG/-TGTTA 1 -- int11Minor allele frequency- -:0.50CSA 2
    rs1855265761,2
    --118474558(+) AAACAA/GCATTT 1 -- int10--------
    rs1904291781,2
    C--118474601(+) ACCAAA/CCAAAG 1 -- int10--------
    rs1816595641,2
    --118474635(+) AAACAA/GCTCCT 1 -- int10--------
    rs1163725361,2
    C,F--118474642(+) TCCTCA/GTAAAA 1 -- int11Minor allele frequency- G:0.05WA 118
    rs1161729481,2
    C,F--118474688(+) GCATGG/AGTGTT 1 -- int11Minor allele frequency- A:0.04WA 118

    HapMap Linkage Disequilibrium report for WDR3 (118472343 - 118503049 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for WDR3:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv34191CNV Loss18971310
    nsv528470CNV Loss19592680

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604737    OMIM disorders: --

    2 diseases for WDR3:    About MalaCards
    thyroid cancer    thyroiditis


    WDR3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): WDR3
    Human Genome Epidemiology (HuGE) Navigator: WDR3 (1 document)

    Export disorders for WDR3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for WDR3 gene, integrated from 9 sources (see all 37):
    (articles sorted by number of sources associating them with WDR3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and expression analysis of a novel WD repeat gene, WDR3, mapping to 1p12-p13. (PubMed id 10395803)1, 2, 3 Claudio J.O....Hawley R.G. (1999)
    2. WDR3 gene haplotype is associated with thyroid cancer risk in a Spanish population. (PubMed id 20578902)1, 4 Akdi A....VelA!zquez A. (2010)
    3. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (2002)
    4. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. (PubMed id 23667531)1 Cox J.L....Rizzino A. (2013)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    6. Host cell interactome of HIV-1 Rev includes RNA helica ses involved in multiple facets of virus production. (PubMed id 22174317)1 Naji S....Gerace L. (2012)
    7. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    8. Possible role of the WDR3 gene on genome stability in thyroid cancer patients. (PubMed id 23049746)1 Garcia-Quispes W.A....Marcos R. (2012)
    9. Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10885 HGNC: 12755 AceView: WDR3 Ensembl:ENSG00000065183 euGenes: HUgn10885
    ECgene: WDR3 Kegg: 10885 H-InvDB: WDR3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for WDR3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for WDR3 gene:
    Search GeneIP for patents involving WDR3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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