Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



WDR27 Gene

protein-coding   GIFtS: 46
GCID: GC06M169857

WD Repeat Domain 27

  Search for WDR27
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
WD Repeat Domain 271 2
WD Repeat-Containing Protein 272

External Ids:    HGNC: 212481   Entrez Gene: 2537692   Ensembl: ENSG000001844657   UniProtKB: A2RRH53   

Export aliases for WDR27 gene to outside databases

Previous GC identifers: GC00U914116 GC06M169675 GC06M167278


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for WDR27 Gene:
WDR27 (WD repeat domain 27) is a protein-coding gene.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NT_025741.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the WDR27 gene promoter:
         Nkx3-1   Nkx3-1 v4   Nkx3-1 v1   STAT5A   E4BP4   AREB6   Nkx3-1 v2   POU2F1   POU2F1a   Nkx3-1 v3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidWDR27 promoter sequence
   Search Chromatin IP Primers for WDR27

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat WDR27


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q27   Ensembl cytogenetic band:  6q27   HGNC cytogenetic band: 6q27

WDR27 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WDR27 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M169857:  view genomic region     (about GC identifiers)

Start:
169,857,303 bp from pter      End:
170,102,159 bp from pter
Size:
244,857 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: WDR27_HUMAN, A2RRH5 (See protein sequence)
Recommended Name: WD repeat-containing protein 27  
Size: 827 amino acids; 90038 Da
Secondary accessions: A5PLM8 C9JGV0 Q5T066
Alternative splicing: 4 isoforms:  A2RRH5-1   A2RRH5-2   A2RRH5-3   A2RRH5-4   (No experimental confirmation available. Ref.2 (BC040606) sequence is in conflict in positions: 845:R->C, 875:L->F)

Explore the universe of human proteins at neXtProt for WDR27: NX_A2RRH5

Explore proteomics data for WDR27 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See WDR27 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001189479.1  NP_872358.4  

    ENSEMBL proteins: 
     ENSP00000416289   ENSP00000411915   ENSP00000449696   ENSP00000330265   ENSP00000397869  
     ENSP00000406114  

    WDR27 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for WDR27
    OriGene Custom MassSpec
    OriGene Custom Protein Services for WDR27
    GenScript Custom Purified and Recombinant Proteins Services for WDR27
    Novus Biologicals WDR27 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for WDR27

     
    Search eBioscience for Proteins for WDR27 

    WDR27 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for WDR27
    OriGene Custom Antibody Services for WDR27
    Novus Biologicals WDR27 Antibodies
    Abcam antibodies for WDR27
    Cloud-Clone Corp. Antibodies for WDR27
    Search ThermoFisher Antibodies for WDR27
    LSBio Antibodies in human, mouse, rat for WDR27

    WDR27 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for WDR27
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for WDR27
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for WDR27
    Cloud-Clone Corp. CLIAs for WDR27
    Search eBioscience for ELISAs for WDR27 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    WDR: WD repeat domain containing

    4 InterPro protein domains:
     IPR011047 Quinonprotein_ADH-like_supfam
     IPR001680 WD40_repeat
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry A2RRH5

    ProtoNet protein and cluster: A2RRH5

    UniProtKB/Swiss-Prot: WDR27_HUMAN, A2RRH5
    Similarity: Contains 10 WD repeats


    Find genes that share domains with WDR27           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with WDR27           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for WDR27:
     Decreased viability of wild-ty 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for WDR27
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for WDR27

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for WDR27
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for WDR27

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat WDR27 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate WDR27
    SwitchGear 3'UTR luciferase reporter plasmidWDR27 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for WDR27
    Predesigned siRNA for gene silencing in human, mouse, rat WDR27

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for WDR27

    Clone
    Products:
         
    OriGene clones in human, mouse for WDR27 (see all 7)
    OriGene ORF clones in mouse, rat for WDR27
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): WDR27 (NM_182552)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for WDR27
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR27

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for WDR27
    Browse ESI BIO Cell Lines and PureStem Progenitors for WDR27 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR27


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    endoplasmic reticulum1
    golgi apparatus1
    mitochondrion1
    nucleus1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--

    Find genes that share ontologies with WDR27           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for WDR27
    Interactions:

        Search GeneGlobe Interaction Network for WDR27

    STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

    Selected Interacting proteins for WDR27 (ENSP000003302654) via UniProtKB, MINT, STRING, and/or I2D (see all 15)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ADRM1ENSP000002530034STRING: ENSP00000253003
    PSMA4ENSP000000444624STRING: ENSP00000044462
    PSMD13ENSP000003969374STRING: ENSP00000396937
    PSMD9ENSP000002618174STRING: ENSP00000261817
    ELP3ENSP000002563984STRING: ENSP00000256398
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for WDR27



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for WDR27 gene (2 alternative transcripts): 
    NM_001202550.1  NM_182552.4  

    Unigene Cluster for WDR27:

    WD repeat domain 27
    Hs.131903  [show with all ESTs]
    Unigene Representative Sequence: NM_182552
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000479310 ENST00000448612(uc021zio.1) ENST00000546525 ENST00000441385
    ENST00000467418(uc003qwz.1) ENST00000486490 ENST00000476322 ENST00000496752
    ENST00000464249 ENST00000546953(uc010kkx.3) ENST00000474018 ENST00000333572(uc003qwx.3)
    ENST00000423258(uc003qwv.2 uc003qwy.3) ENST00000420344(uc011egw.1)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat WDR27 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate WDR27
    SwitchGear 3'UTR luciferase reporter plasmidWDR27 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for WDR27
    Predesigned siRNA for gene silencing in human, mouse, rat WDR27
    Clone
    Products:
         
    OriGene clones in human, mouse for WDR27 (see all 7)
    OriGene ORF clones in mouse, rat for WDR27
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): WDR27 (NM_182552)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for WDR27
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR27
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for WDR27
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat WDR27
      QuantiTect SYBR Green Assays in human, mouse, rat WDR27
      QuantiFast Probe-based Assays in human, mouse, rat WDR27

    Additional mRNA sequence: 

    BC035289.1 BC040606.1 BC131633.1 BX648854.1 

    19 DOTS entries:

    DT.100008587  DT.111152  DT.422763  DT.100641697  DT.438920  DT.309527  DT.441796  DT.92062632 
    DT.95295353  DT.409070  DT.102827768  DT.97815815  DT.92030489  DT.102827763  DT.121403674  DT.86841469 
    DT.87046654  DT.40208238  DT.91854374 

    Selected AceView cDNA sequences (see all 140):

    AI743363 AI867917 AA479979 AI207993 BC073148 AA835653 AA450086 AI990380 
    AI300988 H80337 BF061565 AW015631 AW963606 AA824637 AI637948 NM_182552 
    AW300877 AA315265 BQ447208 CA414712 AI917741 CD557568 AW778877 AA372514 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for WDR27 (see all 11)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b · 11c ^ 12 ^ 13 ^ 14a · 14b · 14c ^ 15 ^ 16 ^ 17a · 17b ^ 18 ^
    SP1:                                                  -           -     -     -     -                             -     -                             -         
    SP2:                                                                                                                                                  -         
    SP3:                                                  -                             -                 -           -     -                                       
    SP4:                                                                                -                 -           -     -                 -                     
    SP5:                                                                                                                                                  -     -   

    ExUns: 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^ 27 ^ 28
    SP1:                                                            
    SP2:                                      -                     
    SP3:                                                            
    SP4:                                                            
    SP5:  -     -     -     -                                       


    ECgene alternative splicing isoforms for WDR27

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    WDR27 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATTATTACA
    WDR27 Expression
    About this image

    WDR27 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    WDR27 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.131903
        Custom PCR Arrays for WDR27
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for WDR27
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat WDR27
    QuantiTect SYBR Green Assays in human, mouse, rat WDR27
    QuantiFast Probe-based Assays in human, mouse, rat WDR27
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR27

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for WDR27 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Wdr271 , 5 WD repeat domain 271, 5 71.92(n)1
    63.48(a)1
      17 (8.95 cM)5
    716821  NM_175173.31  NP_780382.21 
     148293315 
    chicken
    (Gallus gallus)
    Aves WDR271 WD repeat domain 27 61.14(n)
    51.84(a)
      100857387  XM_003640958.2  XP_003641006.1 
    lizard
    (Anolis carolinensis)
    Reptilia WDR276
    WD repeat domain 27
    56(a)
    1 ↔ 1
    1(223733395-223856867)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.204282 Transcribed sequence with weak similarity to protein more 74.39(n)    AL855812.2 
    zebrafish
    (Danio rerio)
    Actinopterygii wdr271 WD repeat domain 27 51.02(n)
    43.88(a)
      641503  XM_003199744.2  XP_003199792.2 


    ENSEMBL Gene Tree for WDR27 (if available)
    TreeFam Gene Tree for WDR27 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for WDR27 gene
    1 SIMAP similar gene for WDR27 using alignment to 5 protein entries:     WDR27_HUMAN (see all proteins):
    POC1B

    Find genes that share paralogs with WDR27           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for WDR27 (see all 5682)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1473354681,2
    --169856931(+) CCCACA/GGACAC 2 -- int10--------
    rs77583761,2
    C,F,A,H--169856967(+) ACAGGG/CAGAGG 2 -- int113Minor allele frequency- C:0.34NS EA WA NA CSA 786
    rs1928197311,2
    --169857022(+) ACGCAC/GAACCC 2 -- int10--------
    rs1410386211,2
    --169857150(+) ATGCAA/GAACCT 2 -- int10--------
    rs1170608011,2
    C,F--169857154(+) AGAACC/ATAGGG 2 -- int11Minor allele frequency- A:0.07EA 120
    rs773660541,2
    C,F--169857167(+) GAGGCC/TAGGCT 2 -- int12Minor allele frequency- T:0.06NA EA 240
    rs15354741,2
    C,F,A,H--169857203(-) GTGAGT/GGTGGC 2 -- int110Minor allele frequency- G:0.34NS EA NA WA CSA 782
    rs1853348691,2
    --169857214(+) CATGCA/GGAGCC 2 -- int10--------
    rs1886618181,2
    --169857393(+) ATTATC/GTTTTA 2 -- ut310--------
    rs10479101,2
    C,F,A,H--169857451(-) AATGGC/TGTCCA 2 -- ut3122Minor allele frequency- T:0.38MN NS EA NA WA CSA 2526

    HapMap Linkage Disequilibrium report for WDR27 (169857303 - 170102159 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for WDR27 (see all 38):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2733509CNV Deletion23290073
    esv2733514CNV Deletion23290073
    esv2733512CNV Deletion23290073
    esv2733508CNV Deletion23290073
    esv2733511CNV Deletion23290073
    esv2671793CNV Deletion23128226
    esv2733516CNV Deletion23290073
    esv2668169CNV Deletion23128226
    esv2733507CNV Deletion23290073
    esv2665981CNV Deletion23128226

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing WDR27
    DNA2.0 Custom Variant and Variant Library Synthesis for WDR27

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus

    Find genes that share disorders with WDR27           About GenesLikeMe

    Genetic Association Database (GAD): WDR27
    Human Genome Epidemiology (HuGE) Navigator: WDR27 (4 documents)

    Export disorders for WDR27 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for WDR27 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with WDR27)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    3. Common genetic variation and the control of HIV-1 in humans. (PubMed id 20041166)1, 4 Fellay J....Goldstein D.B. (PLoS Genet. 2009)
    4. A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci. (PubMed id 21980299)1 Bradfield J.P....Hakonarson H. (PLoS Genet. 2011)
    5. WD40 proteins propel cellular networks. (PubMed id 20451393)1 Stirnimann C.U....MA1ller C.W. (Trends Biochem. Sci. 2010)
    6. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)
    7. Diversity of WD-repeat proteins. (PubMed id 18925368)1 Smith T.F. (Subcell. Biochem. 2008)
    8. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)2 Mungall A.J.... Beck S. (Nature 2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 253769 HGNC: 21248 AceView: MGC43690 Ensembl:ENSG00000184465 euGenes: HUgn253769
    ECgene: WDR27 H-InvDB: WDR27

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for WDR27 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for WDR27 gene:
    Search GeneIP for patents involving WDR27

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for WDR27   OriGene RNAi products in human, mouse, rat for WDR27  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for WDR27  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for WDR27  
     OriGene qSTAR qPCR primer pairs in human, mouse for WDR27   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for WDR27   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for WDR27   OriGene Custom Protein Services for WDR27  

     
     
     Block miRNA regulation of human, mouse, rat WDR27 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing WDR27
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat WDR27 Predesigned siRNA for gene silencing in human, mouse, rat WDR27
     QuantiFast Probe-based Assays in human, mouse, rat WDR27 QuantiTect SYBR Green Assays in human, mouse, rat WDR27
     Custom PCR Arrays for WDR27 Search Chromatin IP Primers for WDR27
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat WDR27  Search GeneGlobe Interaction Network for WDR27
     Regulatory tfbs in WDR27 promoter
     GenScript Custom Purified and Recombinant Proteins Services for WDR27 GenScript cDNA clones with any tag delivered in your preferred vector for WDR27
     GenScript Custom Assay Services for WDR27 GenScript Custom overexpressing Cell Line Services for WDR27
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for WDR27
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     WDR27 antibodies
     WDR27 proteins
     Antibodies for WDR27
     See all of Abcam's Antibodies, Kits and Proteins for WDR27
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for WDR27
     Antibodies for WDR27
     ELISAs for WDR27
     CLIAs for WDR27



     Browse ESI BIO Cell Lines and PureStem Progenitors for WDR27
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR27
     SwitchGear 3'UTR luciferase reporter plasmids for WDR27
     SwitchGear Promoter luciferase reporter plasmids for WDR27
     Search ThermoFisher Antibodies for WDR27
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR27
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for WDR27
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for WDR27
     LSBio Antibodies in human, mouse, rat for WDR27
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for WDR27
      Search eBioscience for proteins for WDR27
      Search eBioscience for elisas for WDR27
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      WDR27 gene at Home site.
    Version: 3.12.212 17 Sep 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4