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Aliases & Descriptions for WDR23
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section
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Aliases DKFZp779A1629 2 GL014 1 , 2 OTTHUMP00000164696 2 PRO2389 1 , 2
Descriptions WD repeat domain 23 2
Search outside databases for aliases for WDR23 genePrevious GC identifers: GC14P018371 GC14P022574
Summaries for WDR23 (According to Entrez Gene ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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EntrezGene summary for WDR23 : This gene encodes a WD repeat-containing protein. Multiple alternatively spliced transcriptvariants have been found for this gene, but the full-length nature of some variants has not beendefined. [provided by RefSeq]
Genomic Location for WDR23
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 36) ,
and/or miRBase ,
Genomic Views according to
UCSC and
Ensembl ,
Transcription factor binding sites according to
SABiosciences )About This Section
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Genomic View : UCSC Golden Path with GeneCards custom track Transcription factor binding sites upstream to the WDR23 gene Entrez Gene cytogenetic band: 14q12 Ensembl cytogenetic band: 14q12 HGNC cytogenetic band: 14q11.2 WDR23 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 14 GeneLoc Exon Structure
GeneLoc location for GC14P023653:
(about GC identifiers )
Start:
23,653,861 bp from pter
End:
23,664,291 bp from pter
Size:
10,431 bases
Orientation:
plus strand
RefSeq DNA sequence: NC_000014.7 NT_026437.11 Proteins for WDR23
(According to
1 UniProtKB ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Enzo Life Sciences ,
Abnova ,
OriGene and/or,
Abcam ,
Biochemical Assays by
Invitrogen ,
Millipore ,
R&D Systems ,
Cell Signaling Technology , and/or
Enzo Life Sciences ,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene ,
Antibodies by Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Cell Signaling Technology ,
Abcam ,
Abnova , and/or
Novus Biologicals )
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UniProtKB/Swiss-Prot: WDR23_HUMAN, Q8TEB1 (See
protein sequence )Recommended Name: WD repeat-containing protein 23 Size : 546 amino acids; 61670 Da
Sequence caution : Sequence=AAG44727.1; Type=Frameshift; Positions=514, 516, 519, 535;
Secondary accessions : B3KQ83 Q5D039 Q86U00 Q86U39 Q8NDN2 Q9H2J0 Q9H3A3 Q9H5C9Alternative splicing : 3 isoforms : Q8TEB1-1 Q8TEB1-2 Q8TEB1-3
Post-translational modifications:
View phosphorylation sites using PhosphoSite 2
REFSEQ proteins (2 alternative transcripts):
NP_079506.3 NP_852002.1 ENSEMBL proteins: ENSP00000323680 ENSP00000380142 ENSP00000335410 ENSP00000380146 Human Recombinant Proteins                OriGene Purified Recombinant Human Proteins (see all 2 ): WDR23 Antibodies for WDR23: Assays for WDR23:
Protein
Domains/ Families for WDR23(According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Graphical View of Domain Structure for InterPro Entry Q8TEB1 ProtoNet protein and cluster: Q8TEB1
UniProtKB/Swiss-Prot: WDR23_HUMAN, Q8TEB1 Similarity : Contains 7 WD repeats
Gene Function for WDR23
(According to MGI Jun 06 2009, UniProtKB ,
IUBMB ,and/or Genatlas ,
shRNA from
OriGene ,
Sigma-Aldrich , RNAi from
Sigma-Aldrich ,
RNAi Products ,
Clones , and
Q-PCR Products
from Invitrogen ,
Millipore ,
OriGene , and/or
Abnova ,
siRNAs from
Applied Biosystems ,
SYBR primers from OriGene ,
Cell-based Assays from Millipore ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2 ): NM_025230 Applied Biosystems Silencer ® siRNAs for WDR23 Sigma-Aldrich siRNA for WDR23 Sigma-Aldrich shRNA for WDR23 Explore Sigma-Aldrich super-pooled esiRNAs                OriGene GFP tagged cDNA clones in CMV expression vector (see all 2 ): NM_025230                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 2 ): NM_025230                                  untagged cDNA clones in CMV expression vector (see all 3 ): NM_025230  Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_025230 Pathways & Interactions for WDR23
(Pathways according to Invitrogen
(maps by GeneGo ),
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Proteins Network according to
SABiosciences ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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1 Interacting protein for WDR23 (Q8TEB1 1 ) via UniProtKB, MINT, and/or STRING About this table
Drugs & Compounds for WDR23 (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
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Browse Tocris compounds for WDR23
Transcripts for WDR23(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from Invitrogen ,
Millipore , and/or
Abnova ,
siRNAs from Applied Biosystems ,
Sigma-Aldrich ,
shRNA from
Sigma-Aldrich ,
OriGene ,
Tagged/untagged cDNA clones from
OriGene , Expression Assays from Applied Biosystems )About This Section
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2 ): NM_025230 Sigma-Aldrich siRNA for WDR23 Sigma-Aldrich shRNA for WDR23 Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer ® siRNAs: NM_025230 NM_181357
REFSEQ mRNAs for WDR23 gene (2 alternative transcripts): NM_025230.3 NM_181357.1
Applied Biosystems TaqMan ® Gene Expression Assays: NM_025230 NM_181357
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2 ): NM_025230                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 2 ): NM_025230                                  untagged cDNA clones in CMV expression vector (see all 3 ): NM_025230  
Additional cDNA sequence: AB209073.1 AF130070.1 AF267858.1 AF283773.2 AK027223.1 AK057636.1 AK074296.1 AK094478.1 AK292797.1 AK296742.1 AK307849.1 AL833831.1 BC008858.2 BC067132.1 BX161405.1 BX247970.1 BX648224.1 CR591345.1 CR591826.1 CR593514.1 CR608759.1 CR611586.1 CR612369.1 CR614614.1 CR616798.1
24/42 DOTS entries (see all 42
): DT.100800736 DT.100803170 DT.312352 DT.117168 DT.92410643 DT.100866229 DT.92464285 DT.100866231 DT.100866220 DT.92464288 DT.120792065 DT.91850921 DT.100866221 DT.95361584 DT.95320451 DT.100775953 DT.91860627 DT.100866236 DT.120792296 DT.120792127 DT.100769101 DT.120792179 DT.120792297 DT.95361582
24/382 AceView cDNA sequences (see all 382
):BQ574746 BU176358 BM716221 BG828935 CR612369 AU130368 AL602608 BM474209 NM_203402 BU167583 BU173185 BX161405 BX463696 BM846447 CR614614 BG403808 BU188056 BP346446 AI301190 AW003607 AA332097 AU142106 AK074296 CB994436
highest scoring ESTs for WDR23 :AW006674 AA112485 AA225567 AA225654 AA311169 AA323418 AA334230 AA348966 AA384311 AA554543
Unigene Cluster for WDR23: WD repeat domain 23 Hs.525251 [show with all ESTs ] Unigene Representative Sequence: NM_025230 GeneLoc Exon Structure 5/25 Alternative Splicing Database (ASD) splice patterns (SP) for WDR23 (see all 25
) ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d · 2e ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c ^ 9a · 9b · 9c · SP1 :       -   -   -   -   -   -   -   -   -                               SP2 :                 -   -                                   SP3 :                       -     -   -                         SP4 :                           -                           SP5 :       -   -   -   -   -   -   -   -       -                          
ExUns: 9d ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b SP1 :     -       -                 SP2 :     -       -                 SP3 :     -       -                 SP4 :     -       -                 SP5 :                          
About this scheme ECgene alternative splicing isoforms for WDR23 4 Ensembl transcripts including schematic representations : ENST00000326009
ENST00000396936
ENST00000334688
ENST00000396941
Expression for WDR23
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Expression Assays from
Applied Biosystems
)
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WDR23 expression in normal and diseased human tissues Applied Biosystems TaqMan ® Gene Expression Assays for WDR23 1 / 2 / 3
7 probe-sets matching WDR23 gene Data from
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: CTGGAGGCACSOURCE GeneReport for Unigene cluster: Hs.525251 Expression variation in blood from EXPOLDB for WDR23
Orthologs for WDR23
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
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Orthologs for WDR23 gene from 5/12 species (see all 12
)
About this table Species with no ortholog for WDR23 ENSEMBL Gene Tree for WDR23 Paralogs for WDR23 (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section
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--
SNPs/Variants for WDR23 (According to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Genotyping Reagents from
Applied Biosystems )
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HapMap Linkage Disequilibrium images for WDR23 (up to first 250kb)
Disorders & Mutations for WDR23
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
HGMD, GAD ,
HuGE Navigator ,
BCGD ,
and/or TGDB .)
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Medical News for WDR23 (Possibly Related Articles in
Doctor's Guide )
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Publications for WDR23 (in
PubMed .
Associations of this gene to articles via
1 Novoseek ,
2 HGNC ,
3 Entrez Gene ,
4 UniProtKB/Swiss-Prot ,
5 UniProtKB/TrEMBL ,
6 GAD , and/or
7 PharmGKB )
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6 PubMed articles for WDR23 gene :
Search for WDR23
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing WDR23
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
and/or
H-InvDB )
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Other Databases showing WDR23
(According to HUGE )
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Specialized Databases showing WDR23 (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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-- Services for WDR23 (Reagents available from Applied Biosystems , Antibodies and assays by Cell
Signaling Technology , Abcam , Novus Biologicals ,Sigma-Aldrich , R&D Systems , Millipore , Abnova , and/or Invitrogen , Clones available from OriGene ,and/or Invitrogen , Drugs and/or compounds by Sigma-Aldrich , Enzo Life Sciences , and/or Tocris Bioscience )About This Section
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