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Aliases & Descriptions for WDR20
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section
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Aliases DMR 1 , 2 FLJ33659 1 , 2 MGC33177 1 , 2 MGC33183 2
Descriptions Protein DMR 3 WD repeat domain 20 2
Search outside databases for aliases for WDR20 genePrevious GC identifers: GC14P096421 GC14P100596
Summaries for WDR20 (According to Entrez Gene ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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EntrezGene summary for WDR20 : This gene encodes a WD repeat-containing protein. Multiple alternatively spliced transcriptvariants have been found for this gene, but the full-length nature of some variants has not beendefined. [provided by RefSeq]
Genomic Location for WDR20
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 36) ,
and/or miRBase ,
Genomic Views according to
UCSC and
Ensembl ,
Transcription factor binding sites according to
SABiosciences )About This Section
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Genomic View : UCSC Golden Path with GeneCards custom track Transcription factor binding sites upstream to the WDR20 gene Entrez Gene cytogenetic band: 14q32.31 Ensembl cytogenetic band: 14q32.31 HGNC cytogenetic band: 14q32.31 WDR20 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 14 GeneLoc Exon Structure
GeneLoc location for GC14P101675:
(about GC identifiers )
Start:
101,675,965 bp from pter
End:
101,759,763 bp from pter
Size:
83,799 bases
Orientation:
plus strand
RefSeq DNA sequence: NC_000014.7 NT_026437.11 Proteins for WDR20
(According to
1 UniProtKB ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Enzo Life Sciences ,
Abnova ,
OriGene and/or,
Abcam ,
Biochemical Assays by
Invitrogen ,
Millipore ,
R&D Systems ,
Cell Signaling Technology , and/or
Enzo Life Sciences ,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene ,
Antibodies by Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Cell Signaling Technology ,
Abcam ,
Abnova , and/or
Novus Biologicals )
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UniProtKB/Swiss-Prot: WDR20_HUMAN, Q8TBZ3 (See
protein sequence )Recommended Name: WD repeat-containing protein 20 Size : 569 amino acids; 62893 Da
Secondary accessions : Q8WXX2 Q9UF86Alternative splicing : 2 isoforms : Q8TBZ3-1 Q8TBZ3-2
Post-translational modifications:
View phosphorylation sites using PhosphoSite 2
REFSEQ proteins (4 alternative transcripts):
NP_653175.2 NP_851808.1 NP_851819.1 NP_851825.1 ENSEMBL proteins: ENSP00000341037 ENSP00000299135 ENSP00000314209 ENSP00000335434 ENSP00000385755 Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 2 Gene Ontology (GO) cellular component terms (links to tree view) :
About this table Antibodies for WDR20: Assays for WDR20:
Protein
Domains/ Families for WDR20(According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Graphical View of Domain Structure for InterPro Entry Q8TBZ3 ProtoNet protein and cluster: Q8TBZ3
UniProtKB/Swiss-Prot: WDR20_HUMAN, Q8TBZ3 Similarity : Contains 5 WD repeats
Gene Function for WDR20
(According to MGI Jun 06 2009, UniProtKB ,
IUBMB ,and/or Genatlas ,
shRNA from
OriGene ,
Sigma-Aldrich , RNAi from
Sigma-Aldrich ,
RNAi Products ,
Clones , and
Q-PCR Products
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Millipore ,
OriGene , and/or
Abnova ,
siRNAs from
Applied Biosystems ,
SYBR primers from OriGene ,
Cell-based Assays from Millipore ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 5 ): BC030654 Applied Biosystems Silencer ® siRNAs for WDR20 Sigma-Aldrich siRNA for WDR20 Sigma-Aldrich shRNA for WDR20 Explore Sigma-Aldrich super-pooled esiRNAs                OriGene GFP tagged cDNA clones in CMV expression vector (see all 4 ): NM_144574                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 4 ): NM_144574                                  untagged cDNA clones in CMV expression vector (see all 4 ): NM_144574  Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_181291 Pathways & Interactions for WDR20
(Pathways according to Invitrogen
(maps by GeneGo ),
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Proteins Network according to
SABiosciences ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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5/22 Interacting proteins for WDR20 (ENSP00000335434 3 ) via UniProtKB, MINT, and/or STRING (see all 22
)About this table
Drugs & Compounds for WDR20 (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
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Browse Tocris compounds for WDR20
Transcripts for WDR20(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from Invitrogen ,
Millipore , and/or
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shRNA from
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OriGene ,
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 5 ): BC030654 Sigma-Aldrich siRNA for WDR20 Sigma-Aldrich shRNA for WDR20 Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer ® siRNAs: NM_144574 NM_181291 NM_181302 NM_181308
REFSEQ mRNAs for WDR20 gene (4 alternative transcripts): NM_144574.2 NM_181291.1 NM_181302.1 NM_181308.1
Applied Biosystems TaqMan ® Gene Expression Assays: NM_144574 NM_181291 NM_181302 NM_181308
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 4 ): NM_144574                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 4 ): NM_144574                                  untagged cDNA clones in CMV expression vector (see all 4 ): NM_144574  
Additional cDNA sequence: AB209148.1 AF327354.1 AK054748.1 AK056330.1 AK090978.1 AK130824.1 AK225852.1 AK297727.1 AL133558.1 AL832242.1 BC028387.2 BC030654.2 BX248274.1 BX647751.1 CR599444.1
24/29 DOTS entries (see all 29
): DT.213857 DT.92060722 DT.111888 DT.92416089 DT.91728613 DT.95151401 DT.101971236 DT.95274540 DT.97843329 DT.100794453 DT.101971764 DT.120782022 DT.92065259 DT.100794455 DT.100794451 DT.100794452 DT.120782255 DT.91672950 DT.95274539 DT.101972999 DT.120781802 DT.120782001 DT.91901778 DT.99932361
24/194 AceView cDNA sequences (see all 194
):CB159530 AI435929 AI085828 AK054748 AI911558 AI125926 AW473525 AI168315 AI341938 BM023222 AA885446 AA489728 NM_181291 CB240608 BM968464 BU674132 BE674667 AL832242 BE796137 AK090978 AI337039 BQ130108 BQ581505 CF243166
highest scoring ESTs for WDR20 :AI092930 AA004578 AA131031 AA195670 AA437270 AA812073 AA884060 AA927998 AF327354 AI087332
Unigene Cluster for WDR20: WD repeat domain 20 Hs.36859 [show with all ESTs ] Unigene Representative Sequence: AB209148 GeneLoc Exon Structure 5/21 Alternative Splicing Database (ASD) splice patterns (SP) for WDR20 (see all 21
) ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g · 1h · 1i ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b · 12c ^ 13a · 13b · 13c · SP1 :                 -   -   -   -   -   -   -   -     -     -   -   -   -   -   -   -   SP2 :                 -   -   -   -   -   -   -       -   -   -   -   -   -         SP3 :                 -   -   -   -   -   -   -   -     -     -               SP4 :                 -   -   -   -   -   -   -       -   -   -               SP5 :                 -   -   -   -   -   -   -   -     -   -   -              
ExUns: 13d · 13e · 13f · 13g · 13h ^ 14 ^ 15 ^ 16 SP1 : -   -   -   -   -         SP2 :                 SP3 :                 SP4 :                 SP5 :         -   -   -    
About this scheme ECgene alternative splicing isoforms for WDR20 5 Ensembl transcripts including schematic representations : ENST00000342702
ENST00000299135
ENST00000322340
ENST00000335263
ENST00000401892
Expression for WDR20
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Expression Assays from
Applied Biosystems
)
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WDR20 expression in normal and diseased human tissues Applied Biosystems TaqMan ® Gene Expression Assays for WDR20 1 / 2 / 3
7 probe-sets matching WDR20 gene Data from
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: GCCCTCTGAGSOURCE GeneReport for Unigene cluster: Hs.36859
Orthologs for WDR20
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
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Orthologs for WDR20 gene from 5/14 species (see all 14
)
About this table Species with no ortholog for WDR20 ENSEMBL Gene Tree for WDR20 Paralogs for WDR20 (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section
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Paralogs for WDR20 gene DMWD 2
SNPs/Variants for WDR20 (According to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Genotyping Reagents from
Applied Biosystems )
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HapMap Linkage Disequilibrium images for WDR20 (up to first 250kb)
Disorders & Mutations for WDR20
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
HGMD, GAD ,
HuGE Navigator ,
BCGD ,
and/or TGDB .)
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--
Medical News for WDR20 (Possibly Related Articles in
Doctor's Guide )
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--
Publications for WDR20 (in
PubMed .
Associations of this gene to articles via
1 Novoseek ,
2 HGNC ,
3 Entrez Gene ,
4 UniProtKB/Swiss-Prot ,
5 UniProtKB/TrEMBL ,
6 GAD , and/or
7 PharmGKB )
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10 PubMed articles for WDR20 gene :
Search for WDR20
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing WDR20
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
and/or
H-InvDB )
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Other Databases showing WDR20
(According to HUGE )
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Specialized Databases showing WDR20 (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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-- Services for WDR20 (Reagents available from Applied Biosystems , Antibodies and assays by Cell
Signaling Technology , Abcam , Novus Biologicals ,Sigma-Aldrich , R&D Systems , Millipore , Abnova , and/or Invitrogen , Clones available from OriGene ,and/or Invitrogen , Drugs and/or compounds by Sigma-Aldrich , Enzo Life Sciences , and/or Tocris Bioscience )About This Section
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Products for WDR20:
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