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WDR20 Gene

protein-coding   GIFtS: 50
GCID: GC14P102606

WD Repeat Domain 20

  See WDR20-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): antisense

Quality score for the ORGUL clustered with this gene is 3

Aliases
WD Repeat Domain 201 2
DMR2
WD Repeat-Containing Protein 202
Protein DMR3

External Ids:    HGNC: 196671   Entrez Gene: 918332   Ensembl: ENSG000001401537   UniProtKB: Q8TBZ33   
ORGUL members:         

Export aliases for WDR20 gene to outside databases

Previous GC identifers: GC14P096421 GC14P100596 GC14P101675 GC14P082785


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for WDR20 Gene:
This gene encodes a WD repeat-containing protein that functions to preserve and regulate the activity of the
USP12-UAF1 deubiquitinating enzyme complex. Multiple alternatively spliced transcript variants have been found
for this gene. (provided by RefSeq, Jun 2011)

GeneCards Summary for WDR20 Gene:
WDR20 (WD repeat domain 20) is a protein-coding gene. Diseases associated with WDR20 include enamel caries, and mitral valve insufficiency. An important paralog of this gene is DMWD.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NT_026437.13  NC_018925.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the WDR20 gene promoter:
         STAT1   Pbx1a   MyoD   Egr-4   CREB   deltaCREB   Pax-4a   Ik-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidWDR20 promoter sequence
   Search Chromatin IP Primers for WDR20

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat WDR20


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q32.31   Ensembl cytogenetic band:  14q32.31   HGNC cytogenetic band: 14q32.31

WDR20 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WDR20 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P102606:  view genomic region     (about GC identifiers)

Start:
102,605,840 bp from pter      End:
102,691,184 bp from pter
Size:
85,345 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: WDR20_HUMAN, Q8TBZ3 (See protein sequence)
Recommended Name: WD repeat-containing protein 20  
Size: 569 amino acids; 62893 Da
Sequence caution: Sequence=AAL56014.1; Type=Erroneous initiation;
Secondary accessions: B4DN18 E7EUY8 F8W9S4 G3V2F8 G3V5R0 H0YJJ1 Q86TU2 Q8NCN7 Q8WXX2 Q9UF86
Alternative splicing: 8 isoforms:  Q8TBZ3-1   Q8TBZ3-2   Q8TBZ3-3   Q8TBZ3-4   Q8TBZ3-5   Q8TBZ3-6   Q8TBZ3-7   Q8TBZ3-8   
(No experimental confirmation available)

Explore the universe of human proteins at neXtProt for WDR20: NX_Q8TBZ3

Explore proteomics data for WDR20 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See WDR20 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (8 alternative transcripts): 
    NP_001229343.1  NP_001229344.1  NP_001229345.1  NP_001229346.1  NP_001229347.1  NP_653175.2  NP_851808.1  NP_851825.1  

    ENSEMBL proteins: 
     ENSP00000335434   ENSP00000314209   ENSP00000452470   ENSP00000341037   ENSP00000450636  
     ENSP00000452774   ENSP00000299135   ENSP00000452539   ENSP00000451633   ENSP00000454151  
     ENSP00000452638   ENSP00000406084   ENSP00000395793   ENSP00000437927   ENSP00000443641  

    WDR20 Human Recombinant Protein Products:

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    Novus Biologicals WDR20 Protein
    Novus Biologicals WDR20 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for WDR20

     
    Search eBioscience for Proteins for WDR20 

     
    antibodies-online proteins for WDR20 (4 products) 

     
    antibodies-online peptides for WDR20

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    antibodies-online antibodies for WDR20 (22 products) 

    WDR20 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for WDR20
    Cloud-Clone Corp. CLIAs for WDR20
    Search eBioscience for ELISAs for WDR20 
    antibodies-online kits for WDR20 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    WDR: WD repeat domain containing

    3 InterPro protein domains:
     IPR001680 WD40_repeat
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q8TBZ3

    ProtoNet protein and cluster: Q8TBZ3

    UniProtKB/Swiss-Prot: WDR20_HUMAN, Q8TBZ3
    Similarity: Contains 5 WD repeats


    Find genes that share domains with WDR20           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with WDR20           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for WDR20

    miRNA
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    Block miRNA regulation of human, mouse, rat WDR20 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate WDR20 (see all 47):
    hsa-miR-302d hsa-miR-520e hsa-miR-374a hsa-miR-301a hsa-miR-519a hsa-miR-374c hsa-miR-372 hsa-miR-302b
    SwitchGear 3'UTR luciferase reporter plasmidWDR20 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for WDR20
    Predesigned siRNA for gene silencing in human, mouse, rat WDR20

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for WDR20

    Clone
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    OriGene clones in human, mouse for WDR20 (see all 20)
    OriGene ORF clones in mouse, rat for WDR20
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): WDR20 (NM_181291)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for WDR20
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR20

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for WDR20 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR20


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2
    golgi apparatus1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for WDR20
    Interactions:

        Search GeneGlobe Interaction Network for WDR20

    STRING Interaction Network Preview (showing 5 interactants - click image to see 21)

    Selected Interacting proteins for WDR20 (Q8TBZ33 ENSP000003354344) via UniProtKB, MINT, STRING, and/or I2D (see all 30)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COL11A2P139423, ENSP000003638404I2D: score=2 STRING: ENSP00000363840
    ENSG00000206290P139423I2D: score=2 
    ENSG00000227801P139423I2D: score=2 
    ENSG00000230930P139423I2D: score=2 
    ENSG00000235708P139423I2D: score=2 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for WDR20



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for WDR20 gene (9 alternative transcripts): 
    NM_001242414.1  NM_001242415.1  NM_001242416.1  NM_001242417.1  NM_001242418.1  NM_144574.3  NM_181291.2  NM_181308.2  
    NM_181302.1  

    Unigene Cluster for WDR20:

    WD repeat domain 20
    Hs.36859  [show with all ESTs]
    Unigene Representative Sequence: BX647751
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 22):
    ENST00000557485 ENST00000335263(uc001yld.3 uc001yle.3) ENST00000322340(uc001ylc.3)
    ENST00000561154 ENST00000555879 ENST00000342702(uc001ylf.3 uc001ykz.3 uc010txu.2)
    ENST00000556807 ENST00000558567 ENST00000299135 ENST00000556094 ENST00000556511
    ENST00000557186 ENST00000558854 ENST00000559708 ENST00000558135 ENST00000558448
    ENST00000555973 ENST00000559478
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat WDR20 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate WDR20 (see all 47):
    hsa-miR-302d hsa-miR-520e hsa-miR-374a hsa-miR-301a hsa-miR-519a hsa-miR-374c hsa-miR-372 hsa-miR-302b
    SwitchGear 3'UTR luciferase reporter plasmidWDR20 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for WDR20
    Predesigned siRNA for gene silencing in human, mouse, rat WDR20
    Clone
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    OriGene clones in human, mouse for WDR20 (see all 20)
    OriGene ORF clones in mouse, rat for WDR20
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): WDR20 (NM_181291)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for WDR20
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR20
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for WDR20
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat WDR20
      QuantiTect SYBR Green Assays in human, mouse, rat WDR20
      QuantiFast Probe-based Assays in human, mouse, rat WDR20

    Additional mRNA sequence: 

    AF327354.1 AK054748.1 AK056330.1 AK090580.1 AK090978.1 AK130824.1 AK225852.1 AK297727.1 
    AL133558.1 AL832242.1 AL832500.1 BC028387.2 BC030654.2 BX248274.1 BX647751.1 NR_038354.1 

    Selected DOTS entries (see all 28):

    DT.213857  DT.92060722  DT.111888  DT.92416089  DT.91728613  DT.95151401  DT.95274540  DT.101971764 
    DT.120782022  DT.97843329  DT.100794453  DT.101971236  DT.100794455  DT.92065259  DT.100794451  DT.100794452 
    DT.120782255  DT.95274539  DT.101972999  DT.120781802  DT.120782001  DT.99969779  DT.99973501  DT.91672950 

    Selected AceView cDNA sequences (see all 194):

    H47282 AI911558 BU632577 AW594032 BM686307 NM_181291 BQ101123 AL832242 
    AW514550 AK090580 AK054748 AL832500 NM_181302 AW589337 BQ898027 W52416 
    BU195758 AK056330 BQ581505 AA250983 AA489728 AI341938 BX248274 AI168315 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for WDR20 (see all 21)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g · 1h · 1i ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b · 12c ^ 13a · 13b · 13c ·
    SP1:                                                  -     -     -     -     -     -     -     -           -           -     -     -     -     -     -     -   
    SP2:                                                  -     -     -     -     -     -     -                 -     -     -     -     -     -                     
    SP3:                                                  -     -     -     -     -     -     -     -           -           -                                       
    SP4:                                                  -     -     -     -     -     -     -                 -     -     -                                       
    SP5:                                                  -     -     -     -     -     -     -     -           -     -     -                                       

    ExUns: 13d · 13e · 13f · 13g · 13h ^ 14 ^ 15 ^ 16
    SP1:  -     -     -     -     -                     
    SP2:                                                
    SP3:                                                
    SP4:                                                
    SP5:                          -     -     -         


    ECgene alternative splicing isoforms for WDR20

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    WDR20 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCCTCTGAG
    WDR20 Expression
    About this image

    WDR20 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    WDR20 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.36859
        Custom PCR Arrays for WDR20
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR20

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for WDR20 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Wdr20a5
    Wdr201
    WD repeat domain 20A5
    WD repeat domain 201
    93.5(n)1
    98.23(a)1
      12 (60.78 cM)5
    696411  NM_027149.21  NP_081425.21 
     1107379495 
    chicken
    (Gallus gallus)
    Aves WDR201 WD repeat domain 20 88.56(n)
    98.1(a)
      423464  XM_003641434.2  XP_003641482.2 
    lizard
    (Anolis carolinensis)
    Reptilia WDR206
    WD repeat domain 20
    97(a)
    1 ↔ 1
    GL343232.1(1837284-1889292)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.120322 Xenopus laevis DMR-N9 protein mRNA, partial cds 80.7(n)    AF170334.1 
    zebrafish
    (Danio rerio)
    Actinopterygii 570888782   -- 78.78(n)    57088878 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG64201 CG6420 55.97(n)
    55.35(a)
      43218  NM_143242.2  NP_651499.2 
    worm
    (Caenorhabditis elegans)
    Secernentea hpo-221 hpo-22 49.64(n)
    46.35(a)
      179410  NM_001269254.1  NP_001256183.1 
    soybean
    (Glycine max)
    eudicotyledons BM094053.12   -- 74.63(n)    BM094053.1 


    ENSEMBL Gene Tree for WDR20 (if available)
    TreeFam Gene Tree for WDR20 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for WDR20 gene
    DMWD2  ENSG000002684342  
    2 SIMAP similar genes for WDR20 using alignment to 8 protein entries:     WDR20_HUMAN (see all proteins):
    DKFZp686P0251    DMWD

    Find genes that share paralogs with WDR20           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for WDR20 (see all 1694)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs665308231,2
    C--82843328(+) TTTAT-/TTATTTATTTATTTAT/
    TTATTTATTTATTTATTTAT
    GAGAC
    9 -- int11NA 2
    rs11905871,2
    C,F,H--102608093(-) AAGACG/AGCAGC 9 -- int119Minor allele frequency- A:0.14NS EA NA WA CSA 1295
    rs11905861,2
    C,F,A,H--102608103(-) TATCAC/ATGTCA 9 -- int115Minor allele frequency- A:0.34NS EA NA WA CSA 927
    rs11905851,2
    C,F,A,H--102608252(-) AAAAAT/ATTTTT 9 -- int1 trp37Minor allele frequency- A:0.39NA WA EA 370
    rs1890212541,2
    --102608392(+) TGGGAC/TGCTAT 9 -- int10--------
    rs1151982381,2
    F--102608393(+) GGGACG/ACTATT 9 -- int11Minor allele frequency- A:0.01WA 118
    rs1808628381,2
    --102608474(+) AAATAC/TGTAAA 9 -- int10--------
    rs1853620981,2
    --102608622(+) TTTCCA/GTGAAT 9 -- int10--------
    rs1886140471,2
    --102608761(+) ACAAAC/TATATT 9 -- int10--------
    rs596219221,2
    C,F--102608864(+) TCGTTC/AACTAC 9 -- int13Minor allele frequency- A:0.12WA NA EA 358

    HapMap Linkage Disequilibrium report for WDR20 (102605840 - 102691184 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for WDR20:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2669943CNV Deletion23128226
    esv2678767CNV Deletion23128226
    esv2668977CNV Deletion23128226
    esv2665920CNV Deletion23128226
    nsv819548CNV Loss19587683
    nsv1429CNV Loss18451855
    nsv512376CNV Loss21212237
    dgv25n68CNV Loss17160897
    esv22037CNV Gain19812545

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    2 diseases for WDR20:    
    About MalaCards
    enamel caries    mitral valve insufficiency

    4 diseases from the University of Copenhagen DISEASES database for WDR20:
    Silver-Russell syndrome     Beckwith-Wiedemann syndrome     Enamel caries     Mitral valve insufficiency

    Find genes that share disorders with WDR20           About GenesLikeMe

    Genetic Association Database (GAD): WDR20
    Human Genome Epidemiology (HuGE) Navigator: WDR20 (3 documents)

    Export disorders for WDR20 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for WDR20 gene, integrated from 10 sources (see all 26):
    (articles sorted by number of sources associating them with WDR20)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    5. 14-3-3 proteins sequester a pool of soluble TRIM32 ubiquitin ligase to repress autoubiquitylation and cytoplasmic body formation. (PubMed id 23444366)1 Ichimura T....Hachiya N. (J. Cell. Sci. 2013)
    6. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    7. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    8. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    9. Regulation of histone H2A and H2B deubiquitination and Xenopus development by USP12 and USP46. (PubMed id 21183687)1 Joo H.Y....Wang H. (J. Biol. Chem. 2011)
    10. WDR20 regulates activity of the USP12 x UAF1 deubiquitinating enzyme complex. (PubMed id 20147737)1 Kee Y....D'Andrea A.D. (J. Biol. Chem. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 91833 HGNC: 19667 AceView: WDR20 Ensembl:ENSG00000140153 euGenes: HUgn91833
    ECgene: WDR20 H-InvDB: WDR20

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for WDR20 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for WDR20 gene:
    Search GeneIP for patents involving WDR20

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

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