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Aliases & Descriptions for WDR13
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| DKFZp779C2057 2 | | FLJ20563 2 | | MG21 2 | | OTTHUMP00000025798 2 | | OTTHUMP00000025799 2 |
| | | Descriptions |
|---|
| WD repeat domain 13 2 | | WD repeat domain 13 protein 2 | | located at OATL1 2 |
|
| | Search outside databases for aliases for WDR13 genePrevious GC identifers: GC0XP047258 GC0XP046716 GC0XP047501 GC0XP048203 |
Summaries for WDR13(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| EntrezGene summary for WDR13: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is widely expressed in various tissues, and located in chromosome X. The function of this gene has not been determined. [provided by RefSeq]
|
Genomic Location for WDR13
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the WDR13 gene 
Entrez Gene cytogenetic band: Xp11.23 Ensembl cytogenetic band: Xp11.23 HGNC cytogenetic band: Xp11.23WDR13 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP048332:
(about GC identifiers)
Start:
|
48,332,467 bp from pter |
End:
|
48,348,518 bp from pter |
Size:
|
16,052 bases |
Orientation:
|
plus strand |
RefSeq DNA sequence:- NC_000023.9 NT_079573.3
| Proteins for WDR13
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: WDR13_HUMAN, Q9H1Z4 (See
protein sequence)Recommended Name: WD repeat-containing protein 13 Size: 485 amino acids; 53715 Da
Subcellular location: Nucleus
Secondary accessions: Q06DX1 Q9BUL7 Q9NWW4Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_060353.2
ENSEMBL proteins: ENSP00000218056 ENSP00000343203 ENSP00000365919
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
3 Gene Ontology (GO) cellular component terms (links to tree view): About this table
Antibodies for WDR13: Assays for WDR13: | Protein
Domains/ Families for WDR13(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q9H1Z4
ProtoNet protein and cluster: Q9H1Z4 UniProtKB/Swiss-Prot: WDR13_HUMAN, Q9H1Z4Similarity: Contains 5 WD repeats | Gene Function for WDR13
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_017883
Applied Biosystems Silencer® siRNAs for WDR13
Sigma-Aldrich siRNA for WDR13  Sigma-Aldrich shRNA for WDR13  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_017883                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_017883                                  untagged cDNA clone in CMV expression vector: NM_017883 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_017883
| Pathways & Interactions for WDR13
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| -- |
Drugs & Compounds for WDR13(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for WDR13
|
Transcripts for WDR13(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_017883
Sigma-Aldrich siRNA for WDR13  Sigma-Aldrich shRNA for WDR13  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_017883 REFSEQ mRNAs for WDR13 gene: NM_017883.3
Applied Biosystems TaqMan ® Gene Expression Assays: NM_017883               OriGene GFP tagged cDNA clone in CMV expression vector: NM_017883                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_017883                                  untagged cDNA clone in CMV expression vector: NM_017883  Additional cDNA sequence: AF329819.4 AK000570.1 AK225542.1 AK301186.1 AK314739.1 BC002507.2 BC067094.1 BC080579.1 BX649101.1 CR591373.1 CR593655.1 CR594799.1 CR595978.1 CR597236.1 CR598742.1 CR598919.1 CR601096.1 CR601751.1 CR602069.1 CR602306.1 CR602965.1 CR603392.1 CR604375.1 CR613575.1 CR616329.1 CR619297.1 CR620990.1 CR621485.1 CR623068.1 CR623686.1 CR624965.1 DQ907252.1 DQ907253.1 DQ907254.1 DQ907255.1 L08237.1 24/30 DOTS entries (see all 30
): DT.448318 DT.95369648 DT.121290946 DT.95369636 DT.100030267 DT.100846235 DT.100688082 DT.95369645 DT.100831352 DT.95369633 DT.121290947 DT.100665888 DT.97767429 DT.97855125 DT.100846228 DT.100846237 DT.100846248 DT.92018266 DT.95369647 DT.100846226 DT.100846259 DT.40296783 DT.95369640 DT.100771447 24/458 AceView cDNA sequences (see all 458
):CR598742 AI878966 BG058665 BX113632 AI654318 CR623686 CA488714 BM753291 BM746507 CR597236 BU147000 CR620990 BM742490 BE888289 CR603392 BM821820 BE796085 BM463723 BQ669278 BQ951128 BU739680 F09364 BM055139 BU736394
highest scoring ESTs for WDR13:AI660689 AA074547 AA079858 AA161211 AA161235 AA349220 AA402272 AA477143 AA477390 AA488064 Unigene Cluster for WDR13: WD repeat domain 13 Hs.521973 [show with all ESTs]Unigene Representative Sequence: L08237
GeneLoc Exon Structure
5/13 Alternative Splicing Database (ASD) splice patterns (SP) for WDR13 (see all 13
)
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3a | · | 3b | · | 3c | · | 3d | · | 3e | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | - |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | - |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | - |   | |
| SP4: | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | - |   | - |   | |   | |   | - |   | |
| SP5: | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 12b | ^ | 13a | · | 13b | · | 13c | · | 13d | |
| SP1: | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   |
About this scheme
ECgene alternative splicing isoforms for WDR13
3 Ensembl transcripts including schematic representations: ENST00000218056
ENST00000344046
ENST00000376729
|
Expression for WDR13
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| WDR13 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for WDR13
1 / 2 / 3 4 probe-sets matching WDR13 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.521973 UniProtKB/Swiss-Prot: WDR13_HUMAN, Q9H1Z4Tissue specificity: Widely expressed |
Orthologs for WDR13
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for WDR13 gene from 5/12 species (see all 12
)
About this table Species with no ortholog for WDR13
ENSEMBL Gene Tree for WDR13 | Paralogs for WDR13(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| -- |
SNPs/Variants for WDR13(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for WDR13 (up to first 250kb)
|
Disorders & Mutations for WDR13
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 300512
|
Medical News for WDR13(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for WDR13 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 9 PubMed articles for WDR13 gene: |
Search for WDR13
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing WDR13
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing WDR13
(According to HUGE)
About This Section
| -- |
Specialized Databases showing WDR13(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for WDR13(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for WDR13:

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GeneCards Homepage - Last full update: 2 Jul 2009
Incremental update: 13 Oct 2009
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