Free for academic non-profit institutions. Other users need a Commercial license

Aliases for WDR13 Gene

Aliases for WDR13 Gene

  • WD Repeat Domain 13 2 3
  • WD Repeat-Containing Protein 13 3
  • MG21 3

External Ids for WDR13 Gene

Previous GeneCards Identifiers for WDR13 Gene

  • GC0XP047258
  • GC0XP046716
  • GC0XP047501
  • GC0XP048203
  • GC0XP048332
  • GC0XP048448
  • GC0XP046119

Summaries for WDR13 Gene

Entrez Gene Summary for WDR13 Gene

  • This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is widely expressed in various tissues. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2009]

GeneCards Summary for WDR13 Gene

WDR13 (WD Repeat Domain 13) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR13 Gene

Genomics for WDR13 Gene

Regulatory Elements for WDR13 Gene

Genomic Location for WDR13 Gene

Start:
48,590,042 bp from pter
End:
48,608,867 bp from pter
Size:
18,826 bases
Orientation:
Plus strand

Genomic View for WDR13 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for WDR13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WDR13 Gene

Proteins for WDR13 Gene

  • Protein details for WDR13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H1Z4-WDR13_HUMAN
    Recommended name:
    WD repeat-containing protein 13
    Protein Accession:
    Q9H1Z4
    Secondary Accessions:
    • Q06DW8
    • Q06DX0
    • Q06DX1
    • Q9BUL7
    • Q9NWW4

    Protein attributes for WDR13 Gene

    Size:
    485 amino acids
    Molecular mass:
    53696 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA91261.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for WDR13 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for WDR13 Gene

Proteomics data for WDR13 Gene at MOPED

Post-translational modifications for WDR13 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for WDR13 Gene

No data available for DME Specific Peptides for WDR13 Gene

Domains for WDR13 Gene

Gene Families for WDR13 Gene

HGNC:
  • WDR :WD repeat domain containing

Protein Domains for WDR13 Gene

Suggested Antigen Peptide Sequences for WDR13 Gene

Graphical View of Domain Structure for InterPro Entry

Q9H1Z4

UniProtKB/Swiss-Prot:

WDR13_HUMAN :
  • Q9H1Z4
Similarity:
  • Contains 7 WD repeats.
genes like me logo Genes that share domains with WDR13: view

Function for WDR13 Gene

Gene Ontology (GO) - Molecular Function for WDR13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with WDR13: view

miRNA for WDR13 Gene

miRTarBase miRNAs that target WDR13

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for WDR13 Gene

Localization for WDR13 Gene

Subcellular locations from UniProtKB/Swiss-Prot for WDR13 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for WDR13 Gene COMPARTMENTS Subcellular localization image for WDR13 gene
Compartment Confidence
nucleus 5
cytosol 3
mitochondrion 2
peroxisome 1

Gene Ontology (GO) - Cellular Components for WDR13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with WDR13: view

Pathways for WDR13 Gene

SuperPathways for WDR13 Gene

No Data Available

Interacting Proteins for WDR13 Gene

Selected Interacting proteins: Q9H1Z4-WDR13_HUMAN for WDR13 Gene via I2D

Symbol External ID(s) Details
TGFBR1

Gene Ontology (GO) - Biological Process for WDR13 Gene

None

No data available for Pathways by source for WDR13 Gene

Transcripts for WDR13 Gene

Unigene Clusters for WDR13 Gene

WD repeat domain 13:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for WDR13 Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d ^ 3a · 3b · 3c · 3d · 3e ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b ^ 11 ^ 12a ·
SP1: - - - -
SP2: - - - - -
SP3: - - -
SP4: - - - - - - - - - - - - - -
SP5: - - -
SP6: - - - -
SP7: - -
SP8: -
SP9: - - - - - -
SP10: - - -
SP11: - - - - - - -
SP12:
SP13:

ExUns: 12b ^ 13a · 13b · 13c · 13d
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:

Relevant External Links for WDR13 Gene

GeneLoc Exon Structure for
WDR13
ECgene alternative splicing isoforms for
WDR13

Expression for WDR13 Gene

mRNA expression in normal human tissues for WDR13 Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for WDR13 Gene

SOURCE GeneReport for Unigene cluster for WDR13 Gene Hs.521973

mRNA Expression by UniProt/SwissProt for WDR13 Gene

Q9H1Z4-WDR13_HUMAN
Tissue specificity: Widely expressed
genes like me logo Genes that share expressions with WDR13: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for WDR13 Gene

Orthologs for WDR13 Gene

This gene was present in the common ancestor of chordates.

Orthologs for WDR13 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia WDR13 35
  • 99.86 (n)
  • 100 (a)
WDR13 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia WDR13 35
  • 92.03 (n)
  • 99.79 (a)
WDR13 36
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia WDR13 35
  • 92.92 (n)
  • 99.59 (a)
WDR13 36
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Wdr13 35
  • 90.38 (n)
  • 99.18 (a)
Wdr13 16
Wdr13 36
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia WDR13 36
  • 64 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia WDR13 36
  • 83 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Wdr13 35
  • 89.82 (n)
  • 98.98 (a)
chicken
(Gallus gallus)
Aves WDR13 35
  • 73.83 (n)
  • 75.56 (a)
WDR13 36
  • 70 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia WDR13 36
  • 89 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.15354 35
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.13608 35
zebrafish
(Danio rerio)
Actinopterygii wdr13 35
  • 74.69 (n)
  • 83.4 (a)
wdr13 36
  • 83 (a)
OneToOne
wufa04f02 35
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.2089 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 57 (a)
OneToOne
Species with no ortholog for WDR13:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for WDR13 Gene

ENSEMBL:
Gene Tree for WDR13 (if available)
TreeFam:
Gene Tree for WDR13 (if available)

Paralogs for WDR13 Gene

Selected SIMAP similar genes for WDR13 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with WDR13: view

No data available for Paralogs for WDR13 Gene

Variants for WDR13 Gene

Sequence variations from dbSNP and Humsavar for WDR13 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs170999 -- 48,602,393(-) TGATA(C/T)GTGGA intron-variant
rs180445 -- 48,602,506(-) ACAGG(C/T)CTCTG intron-variant
rs235823 -- 48,592,129(-) ACATT(A/T)AAGCC intron-variant
rs235824 -- 48,597,835(+) CCGGG(G/T)GGGAG upstream-variant-2KB, utr-variant-5-prime, nc-transcript-variant, intron-variant
rs235840 -- 48,604,563(-) TGTGA(C/G)TTCTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for WDR13 Gene

Variant ID Type Subtype PubMed ID
esv32909 CNV Gain+Loss 17666407
nsv528292 CNV Gain 19592680

Relevant External Links for WDR13 Gene

HapMap Linkage Disequilibrium report
WDR13
Human Gene Mutation Database (HGMD)
WDR13
Locus Specific Mutation Databases (LSDB)
WDR13

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WDR13 Gene

Disorders for WDR13 Gene

Relevant External Links for WDR13

Genetic Association Database (GAD)
WDR13
genes like me logo Genes that share disorders with WDR13: view

No data available for UniProtKB/Swiss-Prot for WDR13 Gene

Publications for WDR13 Gene

  1. A highly conserved human gene encoding a novel member of WD-repeat family of proteins (WDR13). (PMID: 12659815) Singh B.N. … Singh L. (Genomics 2003) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. High-throughput mapping of a dynamic signaling network in mammalian cells. (PMID: 15761153) Barrios-Rodiles M. … Wrana J.L. (Science 2005) 3
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3

Products for WDR13 Gene

Sources for WDR13 Gene

Back to Top

Content