Free for academic non-profit institutions. Other users need a Commercial license

Aliases for WDR13 Gene

Aliases for WDR13 Gene

  • WD Repeat Domain 13 2 3 5
  • MG21 3

External Ids for WDR13 Gene

Previous GeneCards Identifiers for WDR13 Gene

  • GC0XP047258
  • GC0XP046716
  • GC0XP047501
  • GC0XP048203
  • GC0XP048332
  • GC0XP048448
  • GC0XP046119

Summaries for WDR13 Gene

Entrez Gene Summary for WDR13 Gene

  • This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is widely expressed in various tissues. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2009]

GeneCards Summary for WDR13 Gene

WDR13 (WD Repeat Domain 13) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for WDR13 Gene

Genomics for WDR13 Gene

Regulatory Elements for WDR13 Gene

Enhancers for WDR13 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around WDR13 on UCSC Golden Path with GeneCards custom track

Genomic Location for WDR13 Gene

48,590,042 bp from pter
48,608,867 bp from pter
18,826 bases
Plus strand

Genomic View for WDR13 Gene

Genes around WDR13 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
WDR13 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for WDR13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for WDR13 Gene

Proteins for WDR13 Gene

  • Protein details for WDR13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    WD repeat-containing protein 13
    Protein Accession:
    Secondary Accessions:
    • Q06DW8
    • Q06DX0
    • Q06DX1
    • Q9BUL7
    • Q9NWW4

    Protein attributes for WDR13 Gene

    485 amino acids
    Molecular mass:
    53696 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA91261.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for WDR13 Gene


neXtProt entry for WDR13 Gene

Proteomics data for WDR13 Gene at MOPED

Post-translational modifications for WDR13 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for WDR13 Gene

No data available for DME Specific Peptides for WDR13 Gene

Domains & Families for WDR13 Gene

Gene Families for WDR13 Gene

Protein Domains for WDR13 Gene

Suggested Antigen Peptide Sequences for WDR13 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 7 WD repeats.
  • Contains 7 WD repeats.
genes like me logo Genes that share domains with WDR13: view

Function for WDR13 Gene

genes like me logo Genes that share phenotypes with WDR13: view

Animal Models for WDR13 Gene

MGI Knock Outs for WDR13:

Animal Model Products

miRNA for WDR13 Gene

miRTarBase miRNAs that target WDR13

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for WDR13 Gene

Localization for WDR13 Gene

Subcellular locations from UniProtKB/Swiss-Prot for WDR13 Gene

Subcellular locations from

Jensen Localization Image for WDR13 Gene COMPARTMENTS Subcellular localization image for WDR13 gene
Compartment Confidence
nucleus 5
cytosol 3
mitochondrion 2
peroxisome 1

Gene Ontology (GO) - Cellular Components for WDR13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with WDR13: view

Pathways & Interactions for WDR13 Gene

SuperPathways for WDR13 Gene

No Data Available

Interacting Proteins for WDR13 Gene

Selected Interacting proteins: Q9H1Z4-WDR13_HUMAN for WDR13 Gene via I2D

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for WDR13 Gene


No data available for Pathways by source and SIGNOR curated interactions for WDR13 Gene

Drugs & Compounds for WDR13 Gene

No Compound Related Data Available

Transcripts for WDR13 Gene

Unigene Clusters for WDR13 Gene

WD repeat domain 13:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for WDR13 Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d ^ 3a · 3b · 3c · 3d · 3e ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b ^ 11 ^ 12a ·
SP1: - - - -
SP2: - - - - -
SP3: - - -
SP4: - - - - - - - - - - - - - -
SP5: - - -
SP6: - - - -
SP7: - -
SP8: -
SP9: - - - - - -
SP10: - - -
SP11: - - - - - - -

ExUns: 12b ^ 13a · 13b · 13c · 13d

Relevant External Links for WDR13 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for WDR13 Gene

mRNA expression in normal human tissues for WDR13 Gene

Protein differential expression in normal tissues from HIPED for WDR13 Gene

This gene is overexpressed in Uterus (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for WDR13 Gene

SOURCE GeneReport for Unigene cluster for WDR13 Gene Hs.521973

mRNA Expression by UniProt/SwissProt for WDR13 Gene

Tissue specificity: Widely expressed.
genes like me logo Genes that share expression patterns with WDR13: view

Protein tissue co-expression partners for WDR13 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for WDR13 Gene

Orthologs for WDR13 Gene

This gene was present in the common ancestor of chordates.

Orthologs for WDR13 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia WDR13 35
  • 92.03 (n)
  • 99.79 (a)
WDR13 36
  • 100 (a)
(Canis familiaris)
Mammalia WDR13 35
  • 92.92 (n)
  • 99.59 (a)
WDR13 36
  • 95 (a)
(Mus musculus)
Mammalia Wdr13 35
  • 90.38 (n)
  • 99.18 (a)
Wdr13 16
Wdr13 36
  • 99 (a)
(Pan troglodytes)
Mammalia WDR13 35
  • 99.86 (n)
  • 100 (a)
WDR13 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Wdr13 35
  • 89.82 (n)
  • 98.98 (a)
(Monodelphis domestica)
Mammalia WDR13 36
  • 64 (a)
(Ornithorhynchus anatinus)
Mammalia WDR13 36
  • 83 (a)
(Gallus gallus)
Aves WDR13 35
  • 73.83 (n)
  • 75.56 (a)
WDR13 36
  • 70 (a)
(Anolis carolinensis)
Reptilia WDR13 36
  • 89 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.13608 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.15354 35
(Danio rerio)
Actinopterygii wdr13 35
  • 74.69 (n)
  • 83.4 (a)
wufa04f02 35
wdr13 36
  • 83 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.2089 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 57 (a)
Species with no ortholog for WDR13:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for WDR13 Gene

Gene Tree for WDR13 (if available)
Gene Tree for WDR13 (if available)

Paralogs for WDR13 Gene

(1) SIMAP similar genes for WDR13 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with WDR13: view

No data available for Paralogs for WDR13 Gene

Variants for WDR13 Gene

Sequence variations from dbSNP and Humsavar for WDR13 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs235842 - 48,601,926(-) TGCCA(C/T)GGTCA nc-transcript-variant, reference, missense
rs170999 -- 48,602,393(-) TGATA(C/T)GTGGA intron-variant
rs180445 -- 48,602,506(-) ACAGG(C/T)CTCTG intron-variant
rs235823 -- 48,592,129(-) ACATT(A/T)AAGCC intron-variant
rs235824 -- 48,597,835(+) CCGGG(G/T)GGGAG intron-variant, nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for WDR13 Gene

Variant ID Type Subtype PubMed ID
esv32909 CNV Gain+Loss 17666407
nsv528292 CNV Gain 19592680

Variation tolerance for WDR13 Gene

Residual Variation Intolerance Score: 33.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.30; 6.68% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for WDR13 Gene

Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for WDR13 Gene

Disorders for WDR13 Gene

Relevant External Links for WDR13

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for WDR13 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for WDR13 Gene

Publications for WDR13 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. High-throughput mapping of a dynamic signaling network in mammalian cells. (PMID: 15761153) Barrios-Rodiles M. … Wrana J.L. (Science 2005) 3

Products for WDR13 Gene

Sources for WDR13 Gene