WDR12 Gene
protein-coding GIFtS: 50
GCID: GC02M203709
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WD repeat domain 12
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Aliases
for WDR12 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| WD Repeat Domain 121 2 | | YTM11 2 | | WD Repeat-Containing Protein 122 3 | | FLJ108811 | | Ribosome Biogenesis Protein WDR122 |
Export aliases for WDR12 gene to outside databasesPrevious GC identifers: GC02M201962 GC02M202469 GC02M203947 GC02M203570 GC02M203453 GC02M195592 |
Summaries
for WDR12 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for WDR12:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric ormultiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycleprogression, signal transduction, apoptosis, and gene regulation. This protein is highly similar to the mouse WDrepeat domain 12 protein at the amino acid level. The protein encoded by this gene is a component of a nucleolarprotein complex that affects maturation of the large ribosomal subunit.(provided by RefSeq, Dec 2008)
UniProtKB/Swiss-Prot: WDR12_HUMAN, Q9GZL7Function: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formationof the 60S ribosome
Gene Wiki entry for WDR12
|
Genomic Views
for WDR12 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_005403.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the WDR12 gene promoter:
Egr-1 FOXO3 AP-4 FOXO3b POU2F1 POU2F1a FOXO3a c-Myb MRF-2 NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for WDR12
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WDR12 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q33.2 Ensembl cytogenetic band: 2q33.2 HGNC cytogenetic band: 2q33.1WDR12 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M203709: view genomic region
(about GC identifiers)
Start:
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203,745,323 bp from pter |
End:
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203,879,521 bp from pter |
Size:
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134,199 bases |
Orientation:
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minus strand |
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Proteins
for WDR12 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: WDR12_HUMAN, Q9GZL7 (See
protein sequence)Recommended Name: Ribosome biogenesis protein WDR12 Size: 423 amino acids; 47708 Da
Subunit: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interactsdirectly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome
Subcellular location: Nucleus, nucleolus. Nucleus, nucleoplasm
Secondary accessions: B3KPA9 Q96HU0 Q9NV80 Q9NYI8Explore the universe of human proteins at neXtProt for WDR12: NX_Q9GZL7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9GZL7
WDR12 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_060726.3
ENSEMBL proteins: ENSP00000261015
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
WDR12 for ontologies About GeneDecksing
WDR12 Antibody Products:
Assay Products for WDR12: |
Protein
Domains /
Families
for WDR12 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
WDR12 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q9GZL7ProtoNet protein and cluster: Q9GZL7 1 Blocks protein family: IPB012972 NLE
UniProtKB/Swiss-Prot: WDR12_HUMAN, Q9GZL7Similarity: Belongs to the WD repeat WDR12/YTM1 familySimilarity: Contains 7 WD repeats |
Function
for WDR12 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: WDR12_HUMAN, Q9GZL7Function: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formationof the 60S ribosomeInduction: By MYC
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WDR12 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WDR12 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for WDR12 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR12 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR12 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table
WDR12 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for WDR12:
Animal Models:
1 MGI phenotypic allele  for Wdr12 (no phenotypes)
WDR12 for phenotypes About GeneDecksing
|
Pathways & Interactions
for WDR12 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Notch Signaling Pathway | |
1  BioSystems Pathway for WDR12
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for WDR12
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/77 Interacting proteins for WDR12 (Q9GZL71, 3 ENSP000002610154) via UniProtKB, MINT, STRING, and/or I2D (see all 77)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
WDR12 for ontologies About GeneDecksing
|
Drugs & Compounds
for WDR12 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for WDR12
Search CenterWatch for drugs/clinical trials and news about WDR12
|
Transcripts
for WDR12 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for WDR12 gene: NM_018256.3 Unigene Cluster for WDR12: WD repeat domain 12 Hs.73291 [show with all ESTs]Unigene Representative Sequence: NM_0182568 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000261015(uc002uzl.3) ENST00000467777 ENST00000464820 ENST00000463824
ENST00000477727 ENST00000475611 ENST00000478869 ENST00000477723
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WDR12 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WDR12 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: WDR12 (NM_018256) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for WDR12 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR12 |
Additional cDNA sequence: AF242546.1 AK001743.1 AK022781.1 AK022782.1 AK056092.1 AK299489.1 BC008082.2 EF011617.1 8 DOTS entries: DT.311726 DT.100785265 DT.100646866 DT.121032090 DT.92434391 DT.95154121 DT.121032085 DT.97780315 24/164 AceView cDNA sequences (see all 164): BU633688 BP871327 BM827535 BU190274 AA807928 AA587202 CR613990 CB131976 BG031765 BX281691 BU166535 BM467114 CB132835 BM800612 BP366830 CK430326 AI278377 AI680131 BG388924 BF170904 AI696102 AK056092 CA420134 CR622430
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for WDR12 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 |
|---|
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| SP1: | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for WDR12
|
Expression
for WDR12 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| WDR12 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAATTACATA
About this image
See WDR12 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for WDR12
SOURCE GeneReport for Unigene cluster: Hs.73291
SABiosciences Custom PCR Arrays for WDR12
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for WDR12
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat WDR12 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDR12 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR12 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR12 |
Orthologs
for WDR12 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for WDR12 gene from 9/32 species (see all 32) About this table
ENSEMBL Gene Tree for WDR12 (if available)
TreeFam Gene Tree for WDR12 (if available) |
Paralogs
for WDR12 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for WDR12 gene
- WDR372
WDR12 for paralogs About GeneDecksing
3 Pseudogenes.org Pseudogenes for WDR12
PGOHUM00000239533 PGOHUM00000246941 PGOHUM00000246013
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Genomic Variants
for WDR12 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for WDR12 (203745323 - 203879521 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for WDR12: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing WDR12 |
|
Disorders
/ Diseases
for WDR12 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
WDR12 for disorders About GeneDecksing
5  diseases for WDR12: About MalaCardsceroid lipofuscinosis neuronal ceroid-lipofuscinosis myocardial infarction gigantism
neuronitis
Human Genome Epidemiology (HuGE) Navigator: WDR12 (4 documents)
Export disorders for WDR12 gene to outside databases
|
Publications
for WDR12 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for WDR12 gene, integrated from 9 sources (see all 26):
(articles sorted by number of sources associating them with WDR12) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Interdependence of Pes1, Bop1, and WDR12 controls nucleolar localization and assembly of the PeBoW complex required for maturation of the 60S ribosomal subunit. (PubMed id 17353269)1, 2, 3 Rohrmoser M.... Eick D. (2007)
- Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation. (PubMed id 16043514)1, 2, 3 Holzel M....Eick D. (2005)
- Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex. (PubMed id 16738141)1, 2 Grimm T....Eick D. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (2002)
- Targeted ubiquitination and degradation of G-protein-c oupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex. (PubMed id 22952844)1 Wu Z....Ma L. (2012)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
|
External Searches for WDR12 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing WDR12 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing WDR12 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing WDR12 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for WDR12 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for WDR12 gene:
Search GeneIP for patents involving WDR12
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for WDR12 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for WDR12 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for WDR12 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for WDR12 | | | OriGene Protein Over-expression Lysate for WDR12 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for WDR12 | | OriGene 3'-UTR Clone for WDR12 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for WDR12 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for WDR12 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for WDR12 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for WDR12 | | OriGene Custom Protein Services for WDR12 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat WDR12 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing WDR12 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WDR12 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat WDR12 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR12 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat WDR12 |
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| |  |  |  |  | | | | |
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 | | | WDR12 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for WDR12 |
|  |  |  | | | | Search ThermoFisher Antibodies for WDR12 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat WDR12 |
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