Aliases for WDR11 Gene
External Ids for WDR11 Gene
Previous HGNC Symbols for WDR11 Gene
Previous GeneCards Identifiers for WDR11 Gene
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus. [provided by RefSeq, Jul 2008]
GeneCards Summary for WDR11 Gene
WDR11 (WD Repeat Domain 11) is a Protein Coding gene. Diseases associated with WDR11 include wdr11-related isolated gonadotropin-releasing hormone deficiency and hypogonadotropic hypogonadism 14 with or without anosmia.