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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

WDR11 Gene

protein-coding   GIFtS: 55
GCID: GC10P122600

WD Repeat Domain 11

(Previous name: bromodomain and WD repeat domain containing 2)
(Previous symbol: BRWD2)
Alzheimer's & Parkinson's Diseases Congress
  See related diseases
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
WD Repeat Domain 111 2     KIAA13513 5
BRWD21 2 3 5     Bromodomain And WD Repeat Domain Containing 21
Bromodomain And WD Repeat-Containing Protein 22 3     HH142
WDR152 3     WD Repeat Domain 152
WD Repeat-Containing Protein 152 3     WD Repeat-Containing Protein 112
DR112 5     

External Ids:    HGNC: 138311   Entrez Gene: 557172   Ensembl: ENSG000001200087   OMIM: 6064175   UniProtKB: Q9BZH63   

Export aliases for WDR11 gene to outside databases

Previous GC identifers: GC10P121529 GC10P121854 GC10P122741 GC10P122275 GC10P116240


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for WDR11 Gene:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of
approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation
of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular
processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is
located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues,
and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests
that it is a candidate gene for the tumor suppressor locus. (provided by RefSeq, Jul 2008)

GeneCards Summary for WDR11 Gene: 
WDR11 (WD repeat domain 11) is a protein-coding gene. Diseases associated with WDR11 include glioblastoma, and alopecia universalis. GO annotations related to this gene include protein binding.

Gene Wiki entry for WDR11 (BRWD2) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NT_030059.13  NC_018921.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for WDR11
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidWDR11 promoter sequence
   Search SABiosciences Chromatin IP Primers for WDR11

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat WDR11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q26   Ensembl cytogenetic band:  10q26.12   HGNC cytogenetic band: 10q26

WDR11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
WDR11 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P122600:  view genomic region     (about GC identifiers)

Start:
122,610,687 bp from pter      End:
122,669,038 bp from pter
Size:
58,352 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: WDR11_HUMAN, Q9BZH6 (See protein sequence)
Recommended Name: WD repeat-containing protein 11  
Size: 1224 amino acids; 136685 Da
Subunit: Interacts with EMX1 (via the N-terminal and the central portion of the protein. The C-terminus does not.)
Subcellular location: Membrane; Single-pass membrane protein (Potential). Cytoplasm. Nucleus. Note=Might be
shuttling between the nucleus and the cytoplasm
Sequence caution: Sequence=BAA92589.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: Q5VWA1 Q9P2J6

Explore the universe of human proteins at neXtProt for WDR11: NX_Q9BZH6

Explore proteomics data for WDR11 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BZH6

  • WDR11 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    WDR11 Protein Expression
    REFSEQ proteins: NP_060587.8  
    ENSEMBL proteins: 
     ENSP00000263461   ENSP00000475076   ENSP00000474880   ENSP00000474595  

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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IDA--
    GO:0005765lysosomal membrane IDA17897319
    GO:0005929cilium IEA--
    GO:0016021integral to membrane IEA--

    WDR11 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    WDR: WD repeat domain containing

    4 InterPro protein domains:
     IPR019775 WD40_repeat_CS
     IPR001680 WD40_repeat
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q9BZH6

    ProtoNet protein and cluster: Q9BZH6

    UniProtKB/Swiss-Prot: WDR11_HUMAN, Q9BZH6
    Similarity: Contains 9 WD repeats


    WDR11 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    WDR11 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for WDR11:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for WDR11 
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    miRTarBase miRNAs that target WDR11:
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    5 QIAGEN miScript miRNA Assays for microRNAs that regulate WDR11:
    hsa-miR-3163 hsa-miR-9* hsa-miR-374b hsa-miR-374a hsa-miR-548n
    SwitchGear 3'UTR luciferase reporter plasmidWDR11 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for WDR11

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    5/7 Interacting proteins for WDR11 (Q9BZH63 ENSP000002634614) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBXN7O948883, ENSP000002963284I2D: score=2 STRING: ENSP00000296328
    GABARAPL1Q9H0R83I2D: score=3 
    CAMKK2Q96RR43I2D: score=1 
    KBTBD7Q8WVZ93I2D: score=1 
    WIPI2Q9Y4P83I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for WDR11

    Search CenterWatch for drugs/clinical trials and news about WDR11

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for WDR11 gene: 
    NM_018117.11  

    Unigene Cluster for WDR11:

    WD repeat domain 11
    Hs.144447  [show with all ESTs]
    Unigene Representative Sequence: AL137699
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000263461(uc010qte.2 uc021pzt.1) ENST00000605202 ENST00000605543
    ENST00000605069 ENST00000605178 ENST00000604585 ENST00000470052 ENST00000497136(uc001lfd.1)
    ENST00000462529 ENST00000604220 ENST00000604509 ENST00000605376 ENST00000478567
    ENST00000605320 ENST00000605659 ENST00000603658 ENST00000604714

    miRNA
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    5 QIAGEN miScript miRNA Assays for microRNAs that regulate WDR11:
    hsa-miR-3163 hsa-miR-9* hsa-miR-374b hsa-miR-374a hsa-miR-548n
    SwitchGear 3'UTR luciferase reporter plasmidWDR11 3' UTR sequence
    Inhib. RNA
    Products:
         
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat WDR11

    Additional mRNA sequence: 

    AB037772.2 AF320223.1 AK000579.1 AK001368.1 AK025050.1 AK092984.1 AK299524.1 AK301761.1 
    AK315145.1 AL137699.1 BC040469.1 BC071564.1 

    15 DOTS entries:

    DT.316698  DT.100781008  DT.100781006  DT.211849  DT.100781003  DT.100781007  DT.86844723  DT.91855659 
    DT.121264942  DT.40215187  DT.121264920  DT.121264983  DT.65284169  DT.92437188  DT.91850479 

    24/251 AceView cDNA sequences (see all 251):

    AA284135 BQ130051 CF593772 BQ130302 AK001368 AI140912 BM970662 AA954748 
    AA358765 BM510690 AA769523 AI659435 CA438540 AI569636 AI160395 BM721711 
    BU619984 AA969234 CB122062 BM677300 BF196913 CK905808 AA432080 AA789241 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    WDR11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATAAATAAAT
    WDR11 Expression
    About this image


    See WDR11 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for WDR11

    SOURCE GeneReport for Unigene cluster: Hs.144447

    UniProtKB/Swiss-Prot: WDR11_HUMAN, Q9BZH6
    Tissue specificity: Ubiquitous

        SABiosciences Expression via Pathway-Focused PCR Array including WDR11: 
              Epigenetic Chromatin Remodeling Factors in human mouse rat

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for WDR11 gene from 8/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Wdr111 , 5 WD repeat domain 111, 5 87.29(n)1
    94.35(a)1
      7 (72.37 cM)5
    2074251  NM_172255.31  NP_758459.21 
     1295918635 
    chicken
    (Gallus gallus)
    Aves WDR111 WD repeat domain 11 78.88(n)
    87.05(a)
      423935  XM_421795.3  XP_421795.2 
    lizard
    (Anolis carolinensis)
    Reptilia WDR116
    WD repeat domain 11
    86(a)
    1 ↔ 1
    3(65191921-65251045)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.27672 Xenopus laevis transcribed sequence with moderate similarity more 75.59(n)    CD255907.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wdr111 WD repeat domain 11 70.48(n)
    77.68(a)
      558865  XM_682139.4  XP_687231.3 
    worm
    (Caenorhabditis elegans)
    Secernentea Y110A7A.91 Protein Y110A7A.9 44.41(n)
    31.3(a)
      172144  NM_001026547.2  NP_001021718.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G266101 Transducin family protein / WD-40 repeat family protein 40.56(n)
    26.43(a)
      817202  NM_179752.1  NP_850083.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g01370001 hypothetical protein 41.36(n)
    28.64(a)
      4328234  NM_001052361.1  NP_001045826.2 


    ENSEMBL Gene Tree for WDR11 (if available)
    TreeFam Gene Tree for WDR11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for WDR11 gene
    1 SIMAP similar gene for WDR11 using alignment to 1 protein entry:     WDR11_HUMAN:
    DKFZp434L1715

    WDR11 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1452 SNPs in WDR11 are shown (see all 1452)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2010514801,2,4
    CHypogonadotropic hypogonadism 14 with or without anosmia (HH14)4 untested1122984543(+) ATTCAC/TGGAAC 2 R W mis11Minor allele frequency- T:0.00EU 1323
    rs3182407601,2,4
    CHypogonadotropic hypogonadism 14 with or without anosmia (HH14)4 pathogenic1122988963(+) AAAGTA/GCAATT 2 T A mis10--------
    rs1444405001,2,4
    C,FHypogonadotropic hypogonadism 14 with or without anosmia (HH14)4 untested1122989003(+) TCTGCG/AGGAAG 2 /Q /R mis11Minor allele frequency- A:0.00NA 4550
    rs1390077441,2,4
    C,FHypogonadotropic hypogonadism 14 with or without anosmia (HH14)4 untested1123024577(+) TACTTT/GGATAG 2 /L /F mis11Minor allele frequency- G:0.00NA 4550
    rs1445317021,2,4
    Cuntested1123021836(+) TCTAGA/CAATTT 2 K Q mis11Minor allele frequency- C:0.00NA 4354
    rs32174701,2
    C,F--122619467(-) TGTGTGT/-GTGTG 1 -- int12Minor allele frequency- -:0.50CSA 4
    rs681806641,2
    C--122619467(+) TTGAT-/ACAC  
            
    ACACA
    1 -- int10--------
    rs611850151,2
    C--122624869(+) GATTGT/-TTTTT 1 -- int11Minor allele frequency- -:0.00NA 2
    rs105856351,2
    C--122628458(+) TAACA-/CAATTTT 1 -- int10--------
    rs2019642531,2
    --122628618(+) TACAG-/GTTTTTT 1 -- int10--------

    HapMap Linkage Disequilibrium report for WDR11 (122610687 - 122669038 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for WDR11:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv7573CNV Insertion18451855
    esv269915CNV Insertion20981092
    nsv525609CNV Loss19592680
    nsv428239CNV Gain+Loss18775914
    dgv321e1CNV Complex17122850


    Human Gene Mutation Database (HGMD): WDR11
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing WDR11
    DNA2.0 Custom Variant and Variant Library Synthesis for WDR11

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606417    OMIM disorders: --

    UniProtKB/Swiss-Prot: WDR11_HUMAN, Q9BZH6
  • Note=A chromosomal aberration involving WDR11 is found in a form of glioblastoma. Translocation
    t(10;19)(q26;q13.3) with ZNF320
  • Note=A chromosomal aberration involving WDR11 is found in a form of Kallmann syndrome. Translocation
    46,XY,t(10;12)(q26.12;q13.11)
  • Hypogonadotropic hypogonadism 14 with or without anosmia (HH14) [MIM:614858]: A disorder characterized by
    absent or incomplete sexual maturation by the age of 18 years, in conjunction with low levels of circulating
    gonadotropins and testosterone and no other abnormalities of the hypothalamic-pituitary axis. In some cases, it
    is associated with non-reproductive phenotypes, such as anosmia, cleft palate, and sensorineural hearing loss.
    Anosmia or hyposmia is related to the absence or hypoplasia of the olfactory bulbs and tracts. Hypogonadism is
    due to deficiency in gonadotropin-releasing hormone and probably results from a failure of embryonic migration of
    gonadotropin-releasing hormone-synthesizing neurons. In the presence of anosmia, idiopathic hypogonadotropic
    hypogonadism is referred to as Kallmann syndrome, whereas in the presence of a normal sense of smell, it has been
    termed normosmic idiopathic hypogonadotropic hypogonadism (nIHH). Note=The disease is caused by mutations
    affecting the gene represented in this entry

  • 8 diseases for WDR11:    About MalaCards
    glioblastoma    alopecia universalis    hypogonadotropism    hypersensitivity reaction type ii disease
    alopecia    hypogonadism    schizophrenia    alzheimer's disease

    1 disease from the University of Copenhagen DISEASES database for WDR11:
    Hypersensitivity reaction type II disease

    WDR11 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): WDR11
    Human Genome Epidemiology (HuGE) Navigator: WDR11 (1 document)

    Export disorders for WDR11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for WDR11 gene, integrated from 9 sources (see all 26):
    (articles sorted by number of sources associating them with WDR11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel member of the WD-repeat gene family, WDR11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells. (PubMed id 11536051)1, 2, 3, 9 Chernova O.B....Cowell J.K. (2001)
    2. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2, 3 Nagase T.... Ohara O. (2000)
    3. WDR11, a WD protein that interacts with transcription factor EMX1, is mutated in idiopathic hypogonadotropic hypogonadism and Kallma nn syndrome. (PubMed id 20887964)1, 2 Kim H.G....Layman L.C. (2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
    6. Genome-wide association study of lung function decline in adults with and without asthma. (PubMed id 22424883)4 Imboden M....Probst-Hensch N.M. (2012)
    7. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (2012)
    8. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PubMed id 22589738)1 Fox C.S....Borecki I.B. (2012)
    9. NOTCH1 nuclear interactome reveals key regulators of i ts transcriptional activity and oncogenic function. (PubMed id 23022380)1 Yatim A....Benkirane M. (2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55717 HGNC: 13831 AceView: WDR11 Ensembl:ENSG00000120008 euGenes: HUgn55717
    ECgene: WDR11 H-InvDB: WDR11

    (According to HUGE)
    About This Section
    HUGE: KIAA1351

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for WDR11 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for WDR11 gene:
    Search GeneIP for patents involving WDR11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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